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The map label for this gene is corA [H]

Identifier: 188528132

GI number: 188528132

Start: 1348708

End: 1349664

Strand: Reverse

Name: corA [H]

Synonym: HPSH_06955

Alternate gene names: 188528132

Gene position: 1349664-1348708 (Counterclockwise)

Preceding gene: 188528133

Following gene: 188528131

Centisome position: 83.91

GC content: 37.72

Gene sequence:

>957_bases
ATGGTGAATGTGTTTTTCAAACAGCAAAAATTTGTCATTAAAAAACGCTTTAATGATTTTAATGGCTTTGATATAGAAGA
AAATGAGGTTTTATGGTTTGAGCTCATCAACCCTACGCCCAATGAATTGGCCACTCTAAGCCAAGAATACGCTATCCATT
ACAACACAGACCATTCCCAACGAGTCTCATCAGTTACCAAATATTGGGAAGACAGCTCCAGCGTTACGATCAACGCCTTT
TTCACTAATCAGGATGAAAATGAAACTTTCCACACGGAAATGGCGACCTTTATTTTGTCCAATAACATTCTTTTCACGTT
TTATTACGGGACTTTAGAAATCTTTGATTCTATCCAAAAAAAGGTTTTGGCTAGCCCTAAGAAATTTGAAGACGGGTTTG
ATATTCTAACCAAAATCTTTGAAGTGTATTTTGAAAAAGGGGTAGAATGCCTAGAGTGGATCAACAAACAAACGAGCCTG
TTGCGCAAAAACATCATTTTCAAAGAAACTTCTACGCATGATGATATTTTAGTGCGCTTGTCCAATTTGCAAGAATTTAA
TGTGGCTTTAAGGGATTCCTTTTTTGACAAACGGCGCATTATTACCGCTTTATTAAGGAGCAATAAAGTGGATAGCGATA
CTAAAAATAATTTAAATATCATTTTAACCGATTTTAGCTCTTTAGTGGAGTCTACAACGGTCAATCTCAACTCCCTAGAC
AATATTCAAAACCTGTTCGCTTCTCAAGTCAATGTGGAGCAAAATAAAATCATCAAGCTCTTCACGGTGGCGACCATGGC
GATGATGCCCCCCACTTTGATCGGCACGATTTATGGCATGAATTTTAAATTCATGCCGGAGTTAGAATGGCAATACGGGT
ATCTTTTCGCACTGATTGTCATGGCGATTTCTACGATCCTCCCAGTGGTTTATTTTAAAAAGAAAGGCTGGTTGTAG

Upstream 100 bases:

>100_bases
TATTTCCACCGGTGGGGGAGCGAGTTTGGAATTATTAGAGGGCAAGATTTTACCTTGTTTTGAGGTTTTGGATAAACGCC
ATTAACTCTAAGGATCGCTT

Downstream 100 bases:

>100_bases
CCTTTCATGGAATTTTTGTCCTCACTATTAGATGCTCTTTCTACAACGCATGGCATAATCTCCTTGACTACGCTCACGCT
TTTAGAAATCATTTTAGGGA

Product: magnesium and cobalt transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELATLSQEYAIHYNTDHSQRVSSVTKYWEDSSSVTINAF
FTNQDENETFHTEMATFILSNNILFTFYYGTLEIFDSIQKKVLASPKKFEDGFDILTKIFEVYFEKGVECLEWINKQTSL
LRKNIIFKETSTHDDILVRLSNLQEFNVALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESTTVNLNSLD
NIQNLFASQVNVEQNKIIKLFTVATMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIVMAISTILPVVYFKKKGWL

Sequences:

>Translated_318_residues
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELATLSQEYAIHYNTDHSQRVSSVTKYWEDSSSVTINAF
FTNQDENETFHTEMATFILSNNILFTFYYGTLEIFDSIQKKVLASPKKFEDGFDILTKIFEVYFEKGVECLEWINKQTSL
LRKNIIFKETSTHDDILVRLSNLQEFNVALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESTTVNLNSLD
NIQNLFASQVNVEQNKIIKLFTVATMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIVMAISTILPVVYFKKKGWL
>Mature_318_residues
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELATLSQEYAIHYNTDHSQRVSSVTKYWEDSSSVTINAF
FTNQDENETFHTEMATFILSNNILFTFYYGTLEIFDSIQKKVLASPKKFEDGFDILTKIFEVYFEKGVECLEWINKQTSL
LRKNIIFKETSTHDDILVRLSNLQEFNVALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESTTVNLNSLD
NIQNLFASQVNVEQNKIIKLFTVATMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIVMAISTILPVVYFKKKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=307, Percent_Identity=26.0586319218241, Blast_Score=135, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 37126; Mature: 37126

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELATLSQEYAIHYNTDHSQ
CCCEEEHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHEEEEECCCHHH
RVSSVTKYWEDSSSVTINAFFTNQDENETFHTEMATFILSNNILFTFYYGTLEIFDSIQK
HHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
KVLASPKKFEDGFDILTKIFEVYFEKGVECLEWINKQTSLLRKNIIFKETSTHDDILVRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
SNLQEFNVALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESTTVNLNSLD
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHHH
NIQNLFASQVNVEQNKIIKLFTVATMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
MAISTILPVVYFKKKGWL
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVNVFFKQQKFVIKKRFNDFNGFDIEENEVLWFELINPTPNELATLSQEYAIHYNTDHSQ
CCCEEEHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHEEEEECCCHHH
RVSSVTKYWEDSSSVTINAFFTNQDENETFHTEMATFILSNNILFTFYYGTLEIFDSIQK
HHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
KVLASPKKFEDGFDILTKIFEVYFEKGVECLEWINKQTSLLRKNIIFKETSTHDDILVRL
HHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
SNLQEFNVALRDSFFDKRRIITALLRSNKVDSDTKNNLNIILTDFSSLVESTTVNLNSLD
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECHHHHHHHHCCCCHHHH
NIQNLFASQVNVEQNKIIKLFTVATMAMMPPTLIGTIYGMNFKFMPELEWQYGYLFALIV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCHHHHHHHHHH
MAISTILPVVYFKKKGWL
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]