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The map label for this gene is nuoC [H]

Identifier: 188528051

GI number: 188528051

Start: 1284279

End: 1285076

Strand: Direct

Name: nuoC [H]

Synonym: HPSH_06540

Alternate gene names: 188528051

Gene position: 1284279-1285076 (Clockwise)

Preceding gene: 188528050

Following gene: 188528052

Centisome position: 79.84

GC content: 40.35

Gene sequence:

>798_bases
ATGGTAAGAAAACAATCCCCCTATGAAGATGTACAAAAACAATCGCGCCAGCATGACCCCTATAAAATCATAGAACCCAC
CCCTAAAAAATATTTAGAGGGCAGTGCTTATGAAGTCATTTACAACCACCTTTCTTACAAACATGAGATTTTAGACAAAT
ATATAGAAACTAACACGGCTGTGTTTTGGATCAAAAAAGACGATATTTTTTCTGTCGCTACGACTTTAAGGCATTTGGGT
TATGAATGTTTGAGCGAAATGAGCGCGATAGATTTGTGCGCTAAAAAAGGGCATTTTGAATTGTTTTATCAATTTGTGGG
TTTTAGCGATAGCTGTAAAAACCGCCGTAGGGTGCGCGTGAAATGCATTCTGTTGCCTAATGAAAGCGTGGATTCTTTGA
GTTTTTTATACCGATCGGCTAATTGGAGCGAGAGGGAAGCGTATGACATGCTTGGTATTGTGTTTGACAAACACCCCTAT
TTGAAACGCCTTATCATGCCGCATGATTGGGTGGGCCACCCTTTATTGCGTTCCTATCCGCTTAAAGGCGATGAATTCGC
CCAATGGTATGAAGTGGATAAAATTTTTGGTAAAGAATACCGAGAAGTGGTGGGTAAAGAGCAACGAGACAGCGCGAGAG
TGGATGAAAAAGACACTTTCAATTTCGCCAAAATTGGCTATGAGCAGGGCAAGGGCGAAGAATTAAAAGAAACAGAAGAA
AAGCATGCGTTTAAGAAAATCCCTTTTGTCAAAGATTTGCACAAAATCGCCCCCACTATCTTAAAAAAGAGGCTATAA

Upstream 100 bases:

>100_bases
CGCCGCGTCCAGAGACTTTACAATACGCTCTTATGGTTTTGCAAGATAAAATCAGACGCTCTAAAGCGATCAAACAAGAC
GCTCCTAAAAGGTTGGTGTG

Downstream 100 bases:

>100_bases
AATGGCTCAAAATTTCACGAAACTCAACCCTCAGTTTGAAAACATCATTTTTGAACATGACGACAACCAAATGATTTTAA
ACTTTGGCCCCCAACACCCC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTAVFWIKKDDIFSVATTLRHLG
YECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRVKCILLPNESVDSLSFLYRSANWSEREAYDMLGIVFDKHPY
LKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETEE
KHAFKKIPFVKDLHKIAPTILKKRL

Sequences:

>Translated_265_residues
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTAVFWIKKDDIFSVATTLRHLG
YECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRVKCILLPNESVDSLSFLYRSANWSEREAYDMLGIVFDKHPY
LKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETEE
KHAFKKIPFVKDLHKIAPTILKKRL
>Mature_265_residues
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTAVFWIKKDDIFSVATTLRHLG
YECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRVKCILLPNESVDSLSFLYRSANWSEREAYDMLGIVFDKHPY
LKRLIMPHDWVGHPLLRSYPLKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETEE
KHAFKKIPFVKDLHKIAPTILKKRL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=147, Percent_Identity=30.6122448979592, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI145693162, Length=182, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71990788, Length=103, Percent_Identity=32.0388349514563, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32563621, Length=103, Percent_Identity=32.0388349514563, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24656494, Length=158, Percent_Identity=29.1139240506329, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 31390; Mature: 31390

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTA
CCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCE
VFWIKKDDIFSVATTLRHLGYECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCEEEE
KCILLPNESVDSLSFLYRSANWSEREAYDMLGIVFDKHPYLKRLIMPHDWVGHPLLRSYP
EEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHCC
LKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETEE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHH
KHAFKKIPFVKDLHKIAPTILKKRL
HHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVRKQSPYEDVQKQSRQHDPYKIIEPTPKKYLEGSAYEVIYNHLSYKHEILDKYIETNTA
CCCCCCCHHHHHHHHHCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCE
VFWIKKDDIFSVATTLRHLGYECLSEMSAIDLCAKKGHFELFYQFVGFSDSCKNRRRVRV
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHCCCCEEEE
KCILLPNESVDSLSFLYRSANWSEREAYDMLGIVFDKHPYLKRLIMPHDWVGHPLLRSYP
EEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHCC
LKGDEFAQWYEVDKIFGKEYREVVGKEQRDSARVDEKDTFNFAKIGYEQGKGEELKETEE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHCCCCCCCCHHHHHHH
KHAFKKIPFVKDLHKIAPTILKKRL
HHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA