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The map label for this gene is 188528037

Identifier: 188528037

GI number: 188528037

Start: 1271329

End: 1272351

Strand: Reverse

Name: 188528037

Synonym: HPSH_06460

Alternate gene names: NA

Gene position: 1272351-1271329 (Counterclockwise)

Preceding gene: 188528038

Following gene: 188528036

Centisome position: 79.1

GC content: 35.68

Gene sequence:

>1023_bases
ATGTATCGTAAAGATTTGGACAATTATTTAAAACAACGACTCCCTAAAGCGGTGTTTTTGTATGGGGAGTTTGATTTTTT
TATCCATTATTATATTCAAACGATTAGCTCGCTTTTTAAATGCAATAACCCTGACACAGAAACTTCGTTTTTTTATGCGA
GCGATTATGAAAAAAGCCAAATTGCGACCCTTTTAGAGCAGGATTCTTTATTTGGAGGGAGCAGTTTAGTCATTTTAAAA
CTGGATTTTGTATTGCATAAGAAATTTAAGGAAAATGACATCAATCTTTTTTTAAAAGCTTTAGAGCGGCCTAGCCATAA
CAGGCTTATCATAGGGCTTTATAATTCTAAAAGCGACACCACAAAATACAAATACACTAGCGAAATTATCGTTAAACTTT
TCCAAAAAAGCCCCTTGAAAGATGAAGCAATCCATGCGCGCTTTTTTATCCCTAAAGCGTGGGAGAGTTTGAGATTCTTA
CAAGAAAGGGCGAATTCTTTACATTTAGACATCAGCAGTCATCTTTTAAACGCTCTTTTTGAAACCAATAACGAAGATTT
AAGCATTTCGTTTAACGATTTAGACAAGCTAGCGATATTAAACGCGCCCATCGCTTTAGAAGACATTCAAGAATTAAGCT
CCAATGCGGGGGATATGGATTTACAAAAGCTCATTTTAGGGCTTTTTTTAAAAAAAAGCGTGCTTGATATTTATGATTAT
TTGTTAAAAGAGGGCAAAAAAGATGCGGATATTTTAAGGGGGTTAGAGCGCTATTTTTACCAGCTTTTTTTATTTTTCGC
TCATATTAAAACGAGCGGTTTAATGGATGCTAAAGAGGTTTTAGGCTACGCTCCCCCTAAAGAGATTGCCCAAAATTACG
CTAAAAACGCCCTGCGTTTGAAAGAAGCCGGCTATAAGAGGGTTTTTGAAATTTTTAGGTTATGGCACATTCAAAGCATG
CAAGGGCAAAAGGAATTGGGTTTTTTGTATTTGACCCCCATTCAAAAAATCATCAACCCTTGA

Upstream 100 bases:

>100_bases
AAGGTTTTTAAGTCTTTAGAAAAGGTGCGCGTTAAAATCACGCATGCGGATTTGGTTTTAGGGCAAGTTTGGGGTGAAAT
CACAGAAAGGATTAAAGAGC

Downstream 100 bases:

>100_bases
AAAATGATCTATTTTTGAACTTTAATATTCCAATAAAACTCAATTTAATCCAAAAACAAGCGAAAGCAAGGTATAATCAA
AAGTTTTTTAGACCTTGCTC

Product: DNA polymerase III subunit delta

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MYRKDLDNYLKQRLPKAVFLYGEFDFFIHYYIQTISSLFKCNNPDTETSFFYASDYEKSQIATLLEQDSLFGGSSLVILK
LDFVLHKKFKENDINLFLKALERPSHNRLIIGLYNSKSDTTKYKYTSEIIVKLFQKSPLKDEAIHARFFIPKAWESLRFL
QERANSLHLDISSHLLNALFETNNEDLSISFNDLDKLAILNAPIALEDIQELSSNAGDMDLQKLILGLFLKKSVLDIYDY
LLKEGKKDADILRGLERYFYQLFLFFAHIKTSGLMDAKEVLGYAPPKEIAQNYAKNALRLKEAGYKRVFEIFRLWHIQSM
QGQKELGFLYLTPIQKIINP

Sequences:

>Translated_340_residues
MYRKDLDNYLKQRLPKAVFLYGEFDFFIHYYIQTISSLFKCNNPDTETSFFYASDYEKSQIATLLEQDSLFGGSSLVILK
LDFVLHKKFKENDINLFLKALERPSHNRLIIGLYNSKSDTTKYKYTSEIIVKLFQKSPLKDEAIHARFFIPKAWESLRFL
QERANSLHLDISSHLLNALFETNNEDLSISFNDLDKLAILNAPIALEDIQELSSNAGDMDLQKLILGLFLKKSVLDIYDY
LLKEGKKDADILRGLERYFYQLFLFFAHIKTSGLMDAKEVLGYAPPKEIAQNYAKNALRLKEAGYKRVFEIFRLWHIQSM
QGQKELGFLYLTPIQKIINP
>Mature_340_residues
MYRKDLDNYLKQRLPKAVFLYGEFDFFIHYYIQTISSLFKCNNPDTETSFFYASDYEKSQIATLLEQDSLFGGSSLVILK
LDFVLHKKFKENDINLFLKALERPSHNRLIIGLYNSKSDTTKYKYTSEIIVKLFQKSPLKDEAIHARFFIPKAWESLRFL
QERANSLHLDISSHLLNALFETNNEDLSISFNDLDKLAILNAPIALEDIQELSSNAGDMDLQKLILGLFLKKSVLDIYDY
LLKEGKKDADILRGLERYFYQLFLFFAHIKTSGLMDAKEVLGYAPPKEIAQNYAKNALRLKEAGYKRVFEIFRLWHIQSM
QGQKELGFLYLTPIQKIINP

Specific function: Could be the functional equivalent of DNA polymerase III delta subunit (holA) [H]

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010372 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 39625; Mature: 39625

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRKDLDNYLKQRLPKAVFLYGEFDFFIHYYIQTISSLFKCNNPDTETSFFYASDYEKSQ
CCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHH
IATLLEQDSLFGGSSLVILKLDFVLHKKFKENDINLFLKALERPSHNRLIIGLYNSKSDT
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCC
TKYKYTSEIIVKLFQKSPLKDEAIHARFFIPKAWESLRFLQERANSLHLDISSHLLNALF
CHHHHHHHHHHHHHHCCCCCCHHHHHEEECHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
ETNNEDLSISFNDLDKLAILNAPIALEDIQELSSNAGDMDLQKLILGLFLKKSVLDIYDY
HCCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLKEGKKDADILRGLERYFYQLFLFFAHIKTSGLMDAKEVLGYAPPKEIAQNYAKNALRL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
KEAGYKRVFEIFRLWHIQSMQGQKELGFLYLTPIQKIINP
HHHHHHHHHHHHHHHHHHHCCCCHHCCEEEECCHHHHCCC
>Mature Secondary Structure
MYRKDLDNYLKQRLPKAVFLYGEFDFFIHYYIQTISSLFKCNNPDTETSFFYASDYEKSQ
CCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHH
IATLLEQDSLFGGSSLVILKLDFVLHKKFKENDINLFLKALERPSHNRLIIGLYNSKSDT
HHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEEECCCCCC
TKYKYTSEIIVKLFQKSPLKDEAIHARFFIPKAWESLRFLQERANSLHLDISSHLLNALF
CHHHHHHHHHHHHHHCCCCCCHHHHHEEECHHHHHHHHHHHHHHCCEEEEHHHHHHHHHH
ETNNEDLSISFNDLDKLAILNAPIALEDIQELSSNAGDMDLQKLILGLFLKKSVLDIYDY
HCCCCCEEEECCCCHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LLKEGKKDADILRGLERYFYQLFLFFAHIKTSGLMDAKEVLGYAPPKEIAQNYAKNALRL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHH
KEAGYKRVFEIFRLWHIQSMQGQKELGFLYLTPIQKIINP
HHHHHHHHHHHHHHHHHHHCCCCHHCCEEEECCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]