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The map label for this gene is rpoBC [H]

Identifier: 188527984

GI number: 188527984

Start: 1218301

End: 1226973

Strand: Reverse

Name: rpoBC [H]

Synonym: HPSH_06195

Alternate gene names: 188527984

Gene position: 1226973-1218301 (Counterclockwise)

Preceding gene: 188527986

Following gene: 188527983

Centisome position: 76.28

GC content: 43.54

Gene sequence:

>8673_bases
ATGTCAAAAAAAATTCCCCTAAAAAACCGCTTGAGAGCTGATTTTACAAAAACCCCAACAGATTTAGAAGTCCCTAATTT
ATTATTATTGCAACGAGATAGTTATGATTCTTTTTTGTATTCTAAAGAGGGTAAAGAGAGCGGGATTGAAAAGGTTTTTA
AATCCATTTTCCCTATCCAAGATGAGCATAACCGCATCACTTTAGAATACGCGGGTTGCGAATTTGGCAAGTCTAAATAC
ACTGTTAGAGAAGCGATGGAGAGAGGCATTACCTACTCTATCCCCCTCAAAATTAAAGTGCGCTTGATCTTGTGGGAAAA
AGATACCAAAAGTGGCGAAAAGAACGGCATTAAGGATATTAAAGAACAAAGCATTTTCATTCGTGAGATCCCTTTGATGA
CAGAACGCACTTCATTTATCATTAATGGGGTGGAGCGCGTGGTCGTCAATCAACTCCACAGAAGCCCCGGTGTGATTTTC
AAAGAAGAAGAGTCCAGCACTTCTTTAAACAAGCTCATTTACACAGGGCAAATCATCCCTGATAGGGGTTCGTGGCTGTA
TTTTGAATACGATTCTAAAGATGTTTTATACGCTCGTATCAACAAACGCCGTAAAGTGCCTGTTACTATTTTATTCAGGG
CGATGGACTATCAAAAACAAGACATTATCAAAATGTTCTACCCGCTTGTTAAAGTGCGTTATGAAAACGATAAATATTTG
ATCCCGTTTGCTTCATTAGACGCCAATCAAAGAATGGAATTTGACTTGAAAGATCCTCAAGGCAAGGTTATTCTTTTAGC
GGGAAAAAAGCTCACTTCAAGAAAGATTAAAGAGCTTAAAGAAAACCATTTAGAATGGGTGGAATACCCTATGGATATTT
TACTCAATCGTCATTTAGCTGAGCCTGTTATGGTAGGGAAAGAAGTCTTATTAGACATGCTCACTCAGCTAGATAAGAAT
AGGTTAGAAAAAATCCACGATTTAGGCGTGCAAGAATTTGTGATCATCAACGATCTAGCGTTAGGGCATGACGCTTCCAT
TATCCAATCTTTTTCAGCCGATTCTGAGTCTTTGAAACTACTCAAGCAAACTGAAAAAATTGATGATGAAAACGCTCTAG
CGGCGATTCGTATTCATAAGGTTATGAAGCCAGGCGATCCTGTTACGACTGAAGTGGCTAAGCAGTTTGTCAAAAAACTT
TTCTTTGATCCTGAACGCTATGATTTGACCATGGTGGGCCGTATGAAAATGAATCACAAGTTAGGCTTGCATGTGCCTGA
TTACATTACGACCTTAACGCATGAAGATATTATCACCACCGTTAAATATCTCATGAAGATCAAAAACAATCAGGGCAAGA
TTGATGACAGGGACCACTTGGGCAATCGTAGGATCAGGGCGGTAGGGGAATTATTGGCCAATGAATTGCATTCAGGCTTA
GTGAAAATGCAAAAGACCATTAAAGACAAGCTCACTACCATGAGCGGGACTTTTGATTCGCTCATGCCTCATGACTTGGT
CAATTCTAAAATGATCACAAGCACCATCATGGAATTTTTCATGGGCGGCCAGCTCTCGCAATTTATGGATCAAACTAACC
CCTTGAGTGAAGTTACGCACAAGCGCCGCCTTTCAGCGCTCGGTGAAGGGGGATTGGTGAAAGACAGGGTAGGTTTTGAA
GCTAGGGATGTGCACCCCACGCATTATGGCCGAATTTGCCCCATTGAAACCCCAGAAGGTCAAAATATCGGTTTGATCAA
CACCCTTTCCACTTTCACAAGAGTGAATGATTTAGGCTTTATTGAAGCCCCTTATAAAAAGGTTGTGGATGGCAAGGTAG
TGGGTGAGACGATTTATTTGACCGCTATTCAAGAAGACAGCCACATCATCGCTCCCGCAAGCACCCCCATTGATGAAGAG
GGTAATATTTTAGGCGATTTGATTGAAACGCGCGTGGAAGGCGAGATCGTTTTGAACGAAAAAAGCAAAGTAACCTTAAT
GGATTTAAGCTCTAGCATGCTAGTAGGGGTAGCTGCATCGCTCATTCCTTTCTTAGAGCATGATGACGCCAACCGCGCCT
TAATGGGGACTAACATGCAGCGCCAAGCGGTGCCGTTATTAAGAAACGACGCTCCCATTGTAGGCACAGGGATTGAAAAA
ATTATCGCTAGGGATTCTTGGGGAGCGATCAAAGCCAATCGTGCAGGTGTTGTAGAAAAAATTGATTCTAAAAATATTTA
TATTTTAGGCGAAGGTAAAGAAGAAGCCTATATTGATGCGTATTCTTTGCAAAAAAACTTGCGCACCAACCAAAACACCA
GTTTCAATCAAATCCCTATCGTTAAAGTGGGCGACAAAGTGGAAGCCGGACAAATCATCGCTGATGGCCCTAGCATGGAT
AGAGGCGAGTTAGCGTTAGGGAAAAATGTGCGCGTGGCGTTCATGCCTTGGAATGGCTATAACTTTGAAGACGCTATCGT
GGTGAGTGAGCGCATCACTAAAGATGATATTTTCACTTCCACCCACATTTATGAAAAAGAAGTGGATGCCAGGGAGCTTA
AGCATGGCGTGGAAGAATTTACCGCTGACATTCCTGATGTGAAAGAAGAAGCGCTCGCTCATCTTGATGAAAGCGGGATC
GTTAAAGTGGGCACTTATGTGAGCGCTGGCATGATTTTAGTGGGTAAGACTTCTCCTAAAGGCGAGATTAAAAGCACGCC
TGAAGAGCGGCTTTTAAGGGCTATTTTTGGGGATAAAGCCGGGCATGTGGTCAATAAGAGTTTGTATTGCCCCCCAAGTT
TGGAAGGCACGGTGATTGATGTGAAAGTCTTCACTAAAAAAGGCTATGAGAAAGACGCGCGGGTTTTGAGCGCGTATGAA
GAAGAAAAAGCCAAGCTTGATATGGAGCATTTTGACCGCTTGACCATGCTCAATAGAGAAGAATTGTTGCGCGTCAGTTC
GCTCCTTTCTCAAGCGATTTTAGAAGAGCCTTTCAGCCATAATGGCAAGGATTATAAAGAAGGCGATCAAATCCCTAAAG
AAGAAATCGCTTCAATCAACCGCTTCACTTTGGCTAGTTTGGTGAAAAAGTATTCTAAAGAAGTGCAAAACCACTATGAA
ATCACTAAAAACAATTTCTTAGAGCAAAAGAAAGTCTTGGGCGAAGAGCATGAAGAAAAGCTTTCTATTTTAGAAAAAGA
TGATATTTTGCCTAATGGCGTGATCAAAAAAGTCAAGCTCTATATCGCTACAAAACGAAAGCTTAAAGTGGGCGATAAAA
TGGCAGGAAGGCATGGGAATAAAGGGATTGTGTCTAATATCGTGCCGGTTGCGGACATGCCTTATACCGCTGATGGCGAG
CCTGTAGATATTGTCTTAAACCCTTTAGGCGTGCCAAGCCGCATGAACATCGGGCAGATTTTAGAAATGCATTTAGGCTT
AGTGGGGAAAGAATTTGGGAAACAAATCGCTAGCATGCTAGAGGATAAAACCAAAGATTTTGCCAAAGAACTGCGCGCTA
AAATGCTAGAAATCGCTAACGCCATCAATGGAAAAGACCCCTTGACAATCCATGTGCTTGAGAGTTGTTCTGATGAAGAG
CTTTTGGAATACGCTAAAGATTGGAGCAAGGGCGTTAAGATGGCTATCCCTGTGTTTGAAGGCATCTCGCAAGAAAAATT
TTATAAGCTATTTGAATTAGCCAAGATCGCTATGGATGGCAAAATGGATCTGTATGATGGGCGCACAGGCGAGAAAATGA
GGGAGCGCGTGAATGTGGGCTATATGTATATGATCAAACTCCACCATTTAGTGGATGAAAAAGTCCATGCCAGAAGCACA
GGCCCTTATAGCTTGGTAACGCACCAGCCTGTGGGGGGTAAAGCGCTTTTTGGGGGTCAAAGGTTTGGGGAAATGGAAGT
GTGGGCGCTAGAAGCTTATGGCGCAGCGCACACTCTAAAAGAAATGCTCACCATTAAATCCGATGATATTAGAGGCAGAG
AGAACGCTTATAGGGCTATCGCTAAAGGTGAGCAAGTGGGCGAGAGCGAAATCCCTGAGACTTTCTATGTCTTGACTAAA
GAATTGCAATCGCTCGCTTTGGATATTAATATTTTTGGGGACGATGTGGATGAAGATGGATCGCCTAAACCCATTGTCAT
TAAAGAAGATGACAGGCCTAAAGACTTTAGTTCTTTCCAACTCACTCTAGCCAGTCCTGAAAAAATCCATTCTTGGAGTT
ATGGGGAAGTTAAAAAGCCAGAAACGATCAATTATCGCACCCTAAAACCTGAACGAGACGGCTTGTTTTGCATGAAAATC
TTTGGCCCCACTAAAGATTATGAATGCTTGTGCGGTAAATACAAAAAGCCTCGCTTCAAAGACATTGGCACATGCGAAAA
ATGCGGCGTAGCGATCACGCACTCCAAAGTCAGGCGTTTCAGAATGGGGCATATTGAATTAGCCACTCCTGTAGCGCATA
TCTGGTATGTCAATTCCTTGCCTAGCCGTATCGGCACGCTTTTAGGCGTTAAGATGAAAGACTTAGAGCGCGTGTTGTAT
TATGAAGCTTATATCGTTAAAGAGCCAGGCGAAGCCGCTTATGACAATGAAGGCACTAAGCTTGTGATGAAATACGATAT
TTTGAATGAAGAGCAGTATCAAAATATCTCACGAAGATACGAAGACAGGGGCTTTGTAGCGCAAATGGGCGGCGAAGCGA
TCAAGGATTTGCTAGAAGAAATTGATTTGATCACCTTATTGCAGAGTTTGAAAGAAGAAGTGAAAGACACCAATTCTGAT
GCGAAAAAGAAAAAACTCATTAAGCGTTTGAAAGTGGTAGAAAGCTTTTTAAATTCTGGTAACAGGCCTGAGTGGATGAT
GCTCACGGTTTTACCGGTATTGCCACCGGATTTAAGGCCTTTAGTCGCGCTAGATGGCGGGAAGTTTGCGGTCAGCGATG
TGAATGAACTGTATCGTCGTGTCATCAATCGTAACCAACGCTTGAAACGCTTAATGGAGCTTGGGGCACCAGAAATCATT
GTGCGCAATGAAAAAAGGATGCTGCAAGAAGCCGTGGATGTGCTTTTTGATAACGGCCGCAGCACCAATGCGGTTAAAGG
GGCTAACAAGCGCCCTTTAAAATCGCTCAGTGAAATCATTAAAGGCAAGCAAGGGCGTTTCAGGCAAAACCTTTTAGGCA
AGCGCGTGGATTTTTCAGGCAGAAGCGTGATTGTGGTTGGGCCAAACCTCAAGATGGATGAGTGCGGATTGCCTAAAAAC
ATGGCGTTGGAACTCTTCAAACCGCATTTGTTATCCAAGCTTGAAGAGAGAGGCTATGCCACCACGCTCAAACAGGCTAA
ACGCATGATTGAACAAAAAAGCAATGAAGTGTGGGAGTGCTTGCAAGAAATCACAGAAGGGTATCCGGTGCTACTCAACC
GCGCTCCTACTTTGCACAAGCAATCCATTCAAGCGTTCCATCCAAAGCTAATTGATGGCAAAGCGATCCAATTGCACCCG
TTAGTGTGTTCAGCGTTCAATGCCGATTTTGACGGGGACCAAATGGCGGTGCATGTGCCTTTAAGCCAGGAAGCGATCGC
TGAATGCAAGGTGTTGATGCTAAGCTCTATGAATATCCTTTTGCCTGCTAGCGGTAAAGCCGTAGTCATTCCTAGCCAGG
ATATGGTTTTAGGGCTTTATTATCTTTCTTTAGAAAAGAGCGGGGTCAAGGGCGAGCATAAACTTTTTTCTAGCGTGAAT
GAAATCATCACCGCCATTGACACGAAAGAATTAGACATCCACGCAAAGATTAGGGTTTTAGATCAAGGGAATATTATCGC
TACGAGCGCGGGGCGCATGATTATTAAGTCCATTCTGCCTGATTTTATCCCTACTGATTTGTGGAACAGACCCATGAAGA
AAAAAGATATTGGCGTGCTTGTGGATTATGTGCATAAAGTCGGCGGTATCGGCATTACTGCAACCTTTTTGGATAATTTA
AAAACGCTTGGCTTTAGGTATGCGACTAAGGCTGGTATTTCTATCTCTATGGAAGATATTATCACGCCAAAAGACAAGCA
AAAAATGGTGGAAAAAGCCAAAGTAGAGGTTAAGAAAATCCAGCAACAATACGATCAAGGGCTGCTCACTGACCAAGAGC
GTTACAATAAGATCATTGACACTTGGACTGAAGTCAATGACAAAATGAGTAAAGAAATGATGAGCACTATCGCGCAAGAT
AAAGAGGGCTTTAACTCTATTTATATGATGGCAGATAGCGGTGCAAGGGGGAGTGCGGCGCAAATCCGTCAGCTTTCAGC
GATGAGGGGCCTTATGACAAAGCCAGATGGCAGCATCATTGAAACGCCCATTATTTCTAACTTTAAAGAGGGGTTGAATG
TCTTAGAATACTTTAACTCCACGCATGGCGCTAGAAAGGGCTTAGCGGATACAGCGCTAAAAACAGCCAATGCGGGGTAT
TTGACCAGAAAGCTCATTGATGTTTCGCAAAATGTCAAGGTGGTGTCTGATGATTGTGGCACGCATGAAGGGATTGAAAT
CACGGATATTGCGGTGGGGAGTGAGCTGATTGAACCTTTAGAGGAGCGTATTTTTGGGCGCGTTTTATTAGAAGATGTGA
TCGATCCCATTACGAATGAAATCTTGCTTTATGCGGACACTTTGATTGATGAAGAGGGCGCTAAAAAGGTGGTTGAAGCC
GGGATTAAATCCATTACGATCCGCACCCCAGTAACTTGTAAAGCGCCAAAGGGCGTGTGCGCGAAATGCTATGGCTTGAA
TTTGGGCGAAGGCAAGATGAGTTATCCGGGTGAAGCGGTGGGCGTGGTGGCTGCGCAATCTATCGGGGAGCCTGGAACTC
AGCTCACTTTAAGGACTTTCCATGTGGGCGGGACAGCGAGCAGGAGTCAGGATGAGCGCGAAATTGTAGCGAGCAAAGAA
GGTTTTGTGCGTTTCTACAACCTTAGGACTTACACGAATAAAGAGGGTAAAAGCATTATCGCTAACCGCCGTAACGCTTC
TATTTTAGTGGTAGAGCCTAAGATTAAAGCGCCTTTTGATGGGGAATTACGCATTGAAACGGTCTATGAAGAAGTCGTTG
TGAGCGTGAAAAATGGCGATCAAGAAGCTAAATTTGTTTTAAGAAGAAGCGATATTGTCAAGCCAAGCGAATTAGCCGGC
GTTGGCGGTAAGATTGAGGGGAAAGTGTATTTGCCTTATGCTAGTGGGCATAAGGTGCATAAGGGGGGAAGTATCGCTGA
TATTATCCAAGAGGGCTGGAATGTGCCTAATCGCATCCCTTATGCGAGCGAATTGCTAGTCAAGGATAATGACCCTATTG
CGCAAGATGTGTATGCCAAAGAAAAAGGTGCAATCAAATACTATGTTTTAGAGGCTAATCATTTAGAGCGCACCCATGGG
ATCAAAAAGGGCGATATTGTGAGCGAAAAAGGCTTGTTTGCGGTGATAGCTGATGATAATGGTAGGGAAGCCGCTCGCCA
TTATATCGCTAGGGGTTCTGAGATCTTGATTGATGATAATAGTGAAGTGGGCGCTAATAGCGTGATTTCTAAACCCACGA
CTAACACTTTCAAAACGATTGCCACATGGGATCCTTACAACACCCCTATTATTGCGGACTTTAAAGGTAAGGTGGGTTTT
GTGGATATTATCGCAGGGGTTACGGTCGCTGAAAAAGAAGACGAAAATACCGGTACCACAAGCTTAGTGGTGAATGATTA
CATTCCAAGCGGATACAAACCAAGCTTGTTTTTAGAGGGGATTAATGGCGAAGAGGTGCGTTATTTCTTAGAGCCAAAAA
CTTCTATCGCTATTAGCGATGGCGTTAGCGTGGAGCAGGCTGAAGTGTTAGCGAAAATCCCTAAAGCGACCGTTAAATCC
AGGGATATTACCGGGGGTCTCCCAAGGGTTTCGGAACTCTTTGAAGCGAGAAAACCCAAGCCTAAAGATGTGGCGATCCT
TTCTGAAGTTGATGGGATAGTGAGTTTTGGCAAACCCATTCGCAATAAAGAGCACATCATCGTAACCTCCAAAGATGGCC
GTCCCATGGATTATTTTGTGGATAAGGGCAAGCAAATTTTAGTGCATGCTGATGAATTTGTGCATGCGGGAGAAGCGATG
ACGGATGGAGTGGTTTCAAGCCATGATATTTTAAGGATCAGCGGCGAAAAAGAGCTTTATAAATACATTGTGAGCGAAGT
CCAGCAAGTGTATCGCAGGCAGGGGGTAAGCATTGCGGACAAGCACATTGAAATCATTGTTTCTCAAATGCTAAGGCAAG
TGCGTATTTTAGACAGCGGGGATAGCAAATTTATTGAAGGGGATTTAGTCAGTAAAAAACTCTTCAAAGAAGAAAACGCT
CGTGTGATCGCTTTAAAAGGCGAGCCAGCGATTGCTGAACCGGTGCTTTTAGGGATCACTAGAGCAGCTATTGGGAGCGA
TAGCATCATCTCAGCGGCCTCTTTCCAAGAAACGACTAAAGTTTTAACAGAAGCCAGTATCGCTATGAAAAAAGACTTTT
TAGAAGACTTGAAAGAGAATGTGGTGTTGGGGAGGATGATCCCTGTGGGAACAGGCATGTATAAGAATAAAAAAATCGTG
TTAAGAACGCTTGAAGATGACCCTAAATTTTGA

Upstream 100 bases:

>100_bases
TTTTTATCATGGATGGTTCTAAAGTTTAAAGATCCTTTTGCAATGCTTACTTGAATTAATGCATTAAATAACTCAAAATT
TTTGATTAAAGGCTTGAAAT

Downstream 100 bases:

>100_bases
CAAAAAAATCGGTTAAGATTTTTAAAAGAAAAATTAGGGTAAAATGGGAGAACTTTTAGTTTTAAATTTTTAGAATAAGG
AAAAATAGTGCCTACTATCA

Product: DNA-directed RNA polymerase subunit beta/beta'

Products: NA

Alternate protein names: DNA-directed RNA polymerase subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta; DNA-directed RNA polymerase subunit beta'; RNA polymerase beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 2890; Mature: 2889

Protein sequence:

>2890_residues
MSKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKY
TVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIF
KEEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLAEPVMVGKEVLLDMLTQLDKN
RLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKL
FFDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
VKMQKTIKDKLTTMSGTFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFE
ARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEE
GNILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRNDAPIVGTGIEK
IIARDSWGAIKANRAGVVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQIPIVKVGDKVEAGQIIADGPSMD
RGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGI
VKVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYE
ITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGE
PVDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIASMLEDKTKDFAKELRAKMLEIANAINGKDPLTIHVLESCSDEE
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARST
GPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTK
ELQSLALDINIFGDDVDEDGSPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRIGTLLGVKMKDLERVLY
YEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSD
AKKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKN
MALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHP
LVCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVVIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNL
KTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMSTIAQD
KEGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEA
GIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKE
GFVRFYNLRTYTNKEGKSIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGAIKYYVLEANHLERTHG
IKKGDIVSEKGLFAVIADDNGREAARHYIARGSEILIDDNSEVGANSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGF
VDIIAGVTVAEKEDENTGTTSLVVNDYIPSGYKPSLFLEGINGEEVRYFLEPKTSIAISDGVSVEQAEVLAKIPKATVKS
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRPMDYFVDKGKQILVHADEFVHAGEAM
TDGVVSSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENA
RVIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
LRTLEDDPKF

Sequences:

>Translated_2890_residues
MSKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKY
TVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIF
KEEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLAEPVMVGKEVLLDMLTQLDKN
RLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKL
FFDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
VKMQKTIKDKLTTMSGTFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFE
ARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEE
GNILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRNDAPIVGTGIEK
IIARDSWGAIKANRAGVVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQIPIVKVGDKVEAGQIIADGPSMD
RGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGI
VKVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYE
ITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGE
PVDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIASMLEDKTKDFAKELRAKMLEIANAINGKDPLTIHVLESCSDEE
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARST
GPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTK
ELQSLALDINIFGDDVDEDGSPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRIGTLLGVKMKDLERVLY
YEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSD
AKKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKN
MALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHP
LVCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVVIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNL
KTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMSTIAQD
KEGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEA
GIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKE
GFVRFYNLRTYTNKEGKSIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGAIKYYVLEANHLERTHG
IKKGDIVSEKGLFAVIADDNGREAARHYIARGSEILIDDNSEVGANSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGF
VDIIAGVTVAEKEDENTGTTSLVVNDYIPSGYKPSLFLEGINGEEVRYFLEPKTSIAISDGVSVEQAEVLAKIPKATVKS
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRPMDYFVDKGKQILVHADEFVHAGEAM
TDGVVSSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENA
RVIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
LRTLEDDPKF
>Mature_2889_residues
SKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKYT
VREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFK
EEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYLI
PFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLAEPVMVGKEVLLDMLTQLDKNR
LEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLF
FDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGLV
KMQKTIKDKLTTMSGTFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFEA
RDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEG
NILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRNDAPIVGTGIEKI
IARDSWGAIKANRAGVVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQIPIVKVGDKVEAGQIIADGPSMDR
GELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIV
KVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYEE
EKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYEI
TKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEP
VDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIASMLEDKTKDFAKELRAKMLEIANAINGKDPLTIHVLESCSDEEL
LEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARSTG
PYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTKE
LQSLALDINIFGDDVDEDGSPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKIF
GPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRIGTLLGVKMKDLERVLYY
EAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDA
KKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEIIV
RNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKNM
ALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPL
VCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVVIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVNE
IITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNLK
TLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMSTIAQDK
EGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGYL
TRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEAG
IKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEG
FVRFYNLRTYTNKEGKSIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAGV
GGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGAIKYYVLEANHLERTHGI
KKGDIVSEKGLFAVIADDNGREAARHYIARGSEILIDDNSEVGANSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGFV
DIIAGVTVAEKEDENTGTTSLVVNDYIPSGYKPSLFLEGINGEEVRYFLEPKTSIAISDGVSVEQAEVLAKIPKATVKSR
DITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRPMDYFVDKGKQILVHADEFVHAGEAMT
DGVVSSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENAR
VIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIVL
RTLEDDPKF

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=847, Percent_Identity=26.0920897284534, Blast_Score=196, Evalue=2e-49,
Organism=Homo sapiens, GI39725938, Length=314, Percent_Identity=31.2101910828025, Blast_Score=139, Evalue=5e-32,
Organism=Homo sapiens, GI103471997, Length=607, Percent_Identity=25.3706754530478, Blast_Score=119, Evalue=3e-26,
Organism=Homo sapiens, GI33469941, Length=257, Percent_Identity=30.7392996108949, Blast_Score=115, Evalue=6e-25,
Organism=Homo sapiens, GI238908505, Length=300, Percent_Identity=29.6666666666667, Blast_Score=115, Evalue=6e-25,
Organism=Homo sapiens, GI212286172, Length=257, Percent_Identity=30.7392996108949, Blast_Score=115, Evalue=6e-25,
Organism=Homo sapiens, GI4505941, Length=169, Percent_Identity=29.585798816568, Blast_Score=82, Evalue=9e-15,
Organism=Homo sapiens, GI238908503, Length=138, Percent_Identity=36.231884057971, Blast_Score=75, Evalue=1e-12,
Organism=Escherichia coli, GI1790419, Length=1389, Percent_Identity=46.796256299496, Blast_Score=1221, Evalue=0.0,
Organism=Escherichia coli, GI2367335, Length=990, Percent_Identity=54.5454545454545, Blast_Score=1114, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=899, Percent_Identity=25.5839822024472, Blast_Score=189, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI25145495, Length=490, Percent_Identity=28.5714285714286, Blast_Score=147, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17552304, Length=308, Percent_Identity=29.5454545454545, Blast_Score=118, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17506623, Length=253, Percent_Identity=30.0395256916996, Blast_Score=97, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25144348, Length=146, Percent_Identity=34.2465753424658, Blast_Score=78, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320061, Length=891, Percent_Identity=24.8035914702581, Blast_Score=204, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324690, Length=328, Percent_Identity=31.4024390243902, Blast_Score=141, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324781, Length=300, Percent_Identity=29.3333333333333, Blast_Score=117, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324725, Length=257, Percent_Identity=31.5175097276265, Blast_Score=115, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325267, Length=256, Percent_Identity=29.296875, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI17530899, Length=837, Percent_Identity=25.3285543608124, Blast_Score=180, Evalue=1e-44,
Organism=Drosophila melanogaster, GI281360912, Length=310, Percent_Identity=30.6451612903226, Blast_Score=135, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17647875, Length=357, Percent_Identity=27.4509803921569, Blast_Score=110, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136446, Length=320, Percent_Identity=27.5, Blast_Score=99, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136444, Length=169, Percent_Identity=29.585798816568, Blast_Score=82, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17647877, Length=89, Percent_Identity=42.6966292134831, Blast_Score=74, Evalue=2e-12,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR007120
- InterPro:   IPR000722
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5; PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_po

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 323621; Mature: 323490

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQ
CCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCCCC
DEHNRITLEYAGCEFGKSKYTVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDI
CCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECEEEEEEEEEEECCCCCCCCCCHHHH
KEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEEESSTSLNKLIYTGQIIP
HHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEEECEEEC
DRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
CCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHEEEECCCCEE
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLA
EEEECCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPVMVGKEVLLDMLTQLDKNRLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHH
LKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLFFDPERYDLTMVGRMKMNHK
HHHHHHCCCCCCEEHEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
LGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
VKMQKTIKDKLTTMSGTFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTH
HHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
KRRLSALGEGGLVKDRVGFEARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGF
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCC
IEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEGNILGDLIETRVEGEIVLNE
CCCCHHHHCCCEEECCEEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECC
KSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRNDAPIVGTGIEK
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCHHCCCCCEEECCHHH
IIARDSWGAIKANRAGVVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQIPI
HHHCCCCCCEECCCCCHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHCCCCCCCCCCEEE
VKVGDKVEAGQIIADGPSMDRGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTS
EEECCCCCCCEEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHCCHHHHHCC
THIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIVKVGTYVSAGMILVGKTSPK
CHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEEEEECCCCC
GEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
CCCCCCHHHHHHHHHHCCCCCCEECCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASIN
HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCH
RFTLASLVKKYSKEVQNHYEITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHEEE
YIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQI
EEEECCHHCCCCHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
LEMHLGLVGKEFGKQIASMLEDKTKDFAKELRAKMLEIANAINGKDPLTIHVLESCSDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVG
HHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCC
YMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLK
EEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEHHCHHHHHH
EMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTKELQSLALDINIFGDDVDEDG
HHHHHCCCCCCCHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
SPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
CCCCEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEE
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSL
CCCCCCHHHHHCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHCCCEEECCHHHHEEEHHHH
PSRIGTLLGVKMKDLERVLYYEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRY
HHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
EDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDAKKKKLIKRLKVVESFLNSG
HCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
CCCCEEEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSG
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
RSVIVVGPNLKMDECGLPKNMALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWEC
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHH
LQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPLVCSAFNADFDGDQMAVHVP
HHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEC
LSQEAIAECKVLMLSSMNILLPASGKAVVIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
CCHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVL
HHHHHHCCCEEEEEEEEEEEECCCEEEECCHHHHHHHHCHHHCCHHHHCCCCCCCHHHHH
VDYVHKVGGIGITATFLDNLKTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHH
QQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMSTIAQDKEGFNSIYMMADSGARGSAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHH
QIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCH
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNE
HHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYADTLIDEEGAKKVVEAGIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAV
EEEEHHHHHCCHHHHHHHHCCHHEEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCHH
GVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEGFVRFYNLRTYTNKEGKSII
HHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEEEECCCCCCHHH
ANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
CCCCCCEEEEECCCCCCCCCCCEEHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCC
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAK
CCCEECCEEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHC
EKGAIKYYVLEANHLERTHGIKKGDIVSEKGLFAVIADDNGREAARHYIARGSEILIDDN
CCCCEEEEEEECCHHHHHCCCCCCCEECCCCEEEEEECCCCHHHHHHHHHCCCEEEEECC
SEVGANSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGFVDIIAGVTVAEKEDENTGTT
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHCCEEECCCCCCCCCE
SLVVNDYIPSGYKPSLFLEGINGEEVRYFLEPKTSIAISDGVSVEQAEVLAKIPKATVKS
EEEEECCCCCCCCCCEEEECCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCHHHHCC
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRPMDYFV
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
DKGKQILVHADEFVHAGEAMTDGVVSSHDILRISGEKELYKYIVSEVQQVYRRQGVSIAD
CCCCEEEEECHHHHHCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHH
KHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENARVIALKGEPAIAEPVLLGIT
HHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
RAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEE
LRTLEDDPKF
EEECCCCCCC
>Mature Secondary Structure 
SKKIPLKNRLRADFTKTPTDLEVPNLLLLQRDSYDSFLYSKEGKESGIEKVFKSIFPIQ
CCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCHHHCCCCCHHHHHHHHHHHHCCCC
DEHNRITLEYAGCEFGKSKYTVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDI
CCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECEEEEEEEEEEECCCCCCCCCCHHHH
KEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEEESSTSLNKLIYTGQIIP
HHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEEECEEEC
DRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
CCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHEEEECCCCEE
IPFASLDANQRMEFDLKDPQGKVILLAGKKLTSRKIKELKENHLEWVEYPMDILLNRHLA
EEEECCCCCCCEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPVMVGKEVLLDMLTQLDKNRLEKIHDLGVQEFVIINDLALGHDASIIQSFSADSESLKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCHHHHHHHCCCHHHHHH
LKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLFFDPERYDLTMVGRMKMNHK
HHHHHHCCCCCCEEHEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
LGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
VKMQKTIKDKLTTMSGTFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTH
HHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
KRRLSALGEGGLVKDRVGFEARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGF
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCC
IEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEGNILGDLIETRVEGEIVLNE
CCCCHHHHCCCEEECCEEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECC
KSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRNDAPIVGTGIEK
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHCCCHHCCCCCEEECCHHH
IIARDSWGAIKANRAGVVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQIPI
HHHCCCCCCEECCCCCHHHCCCCCCEEEEECCCCCCEEEHHHHHHHHCCCCCCCCCCEEE
VKVGDKVEAGQIIADGPSMDRGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTS
EEECCCCCCCEEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHCCHHHHHCC
THIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIVKVGTYVSAGMILVGKTSPK
CHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEEEEECCCCC
GEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
CCCCCCHHHHHHHHHHCCCCCCEECCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASIN
HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCH
RFTLASLVKKYSKEVQNHYEITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHEEE
YIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQI
EEEECCHHCCCCHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
LEMHLGLVGKEFGKQIASMLEDKTKDFAKELRAKMLEIANAINGKDPLTIHVLESCSDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHH
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVG
HHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCC
YMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLK
EEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEHHCHHHHHH
EMLTIKSDDIRGRENAYRAIAKGEQVGESEIPETFYVLTKELQSLALDINIFGDDVDEDG
HHHHHCCCCCCCHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
SPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
CCCCEEEECCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEE
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSL
CCCCCCHHHHHCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHCCCEEECCHHHHEEEHHHH
PSRIGTLLGVKMKDLERVLYYEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRY
HHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
EDRGFVAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDAKKKKLIKRLKVVESFLNSG
HCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
CCCCEEEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSG
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
RSVIVVGPNLKMDECGLPKNMALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWEC
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHH
LQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPLVCSAFNADFDGDQMAVHVP
HHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEC
LSQEAIAECKVLMLSSMNILLPASGKAVVIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
CCHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVL
HHHHHHCCCEEEEEEEEEEEECCCEEEECCHHHHHHHHCHHHCCHHHHCCCCCCCHHHHH
VDYVHKVGGIGITATFLDNLKTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHH
QQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMSTIAQDKEGFNSIYMMADSGARGSAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHH
QIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCH
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNE
HHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYADTLIDEEGAKKVVEAGIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAV
EEEEHHHHHCCHHHHHHHHCCHHEEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCHH
GVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEGFVRFYNLRTYTNKEGKSII
HHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEEEECCCCCCHHH
ANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGDQEAKFVLRRSDIVKPSELAG
CCCCCCEEEEECCCCCCCCCCCEEHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCC
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAK
CCCEECCEEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHC
EKGAIKYYVLEANHLERTHGIKKGDIVSEKGLFAVIADDNGREAARHYIARGSEILIDDN
CCCCEEEEEEECCHHHHHCCCCCCCEECCCCEEEEEECCCCHHHHHHHHHCCCEEEEECC
SEVGANSVISKPTTNTFKTIATWDPYNTPIIADFKGKVGFVDIIAGVTVAEKEDENTGTT
CCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCCHHHHHHCCEEECCCCCCCCCE
SLVVNDYIPSGYKPSLFLEGINGEEVRYFLEPKTSIAISDGVSVEQAEVLAKIPKATVKS
EEEEECCCCCCCCCCEEEECCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHCCHHHHCC
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRPMDYFV
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHH
DKGKQILVHADEFVHAGEAMTDGVVSSHDILRISGEKELYKYIVSEVQQVYRRQGVSIAD
CCCCEEEEECHHHHHCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHH
KHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENARVIALKGEPAIAEPVLLGIT
HHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
RAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEE
LRTLEDDPKF
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA