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The map label for this gene is yeiJ [C]

Identifier: 188527968

GI number: 188527968

Start: 1199813

End: 1201069

Strand: Reverse

Name: yeiJ [C]

Synonym: HPSH_06115

Alternate gene names: 188527968

Gene position: 1201069-1199813 (Counterclockwise)

Preceding gene: 188527971

Following gene: 188527967

Centisome position: 74.67

GC content: 44.87

Gene sequence:

>1257_bases
ATGATTTTTAGCTCTCTTTTTAGTATTGTAGGGATGGCGGTGCTTTTTCTTATTGCTTGGGTGTTTTCTAGCAATAAAAG
GGCTATTAATTATCGCACGATTATCAGCGCGTTTGTGATCCAGGTGGCTTTGGGGGCGTTGGCTTTATATGTGCCTTTGG
GTAGGGAAATGCTGCAAGGTTTAGCCAGTGGCATACAAAGCGTGATTGGTTATGGCTATGAGGGGGTGCGTTTTTTATTT
GGGAGTCTCGCTCCAAACGCTAAGGGCGATCAAGGGATAGGAGGCTTTATCTTTGCGATCAATGTTTTAGCGATCATTAT
CTTTTTTGCTAGCTTGATTTCACTCCTATACTATTTAAAAATCATGCCTTTAGTGATCAATCTCATCGGTGGGGCGTTGC
AAAAATGCTTAGGCACTTCTAAAGCAGAAAGCATGAGCGCAGCGGCTAATATTTTTGTAGCGCACACAGAAGCGCCCTTA
GTCATTAAACCTTATTTGAAAAGCATGAGCGATTCAGAGATTTTTGCGGTCATGTGCGTGGGCATGGCTAGCGTTGCGGG
GCCGGTGTTGGCCGGGTATGCGAGCATGGGCATTCCTTTGCCTTATTTAATAGCCGCTTCGTTTATGTCCGCTCCTGGGG
GTTTGTTGTTCGCTAAAATCATTTACCCGCAAAACGAAACCATTTCTAGCCATGCAGATGCTTCTGTAGAAAAGCATGTC
AATGCCATAGAAGCTATCGCTAATGGGGCAAGCACAGGGCTAAATTTAGCTTTGCATGTGGGAGCGATGCTTTTAGCCTT
TGTGGGGATGCTCGCACTCATCAACGGGCTTTTAGGGGTTGTAGGGGGATTTTTAGGCATGGAGCATTTGTCTTTGGGGT
TGATTTTAGGCACGCTCTTAAAACCCTTAGCTTTTATGCTAGGCATTCCTTGGAGTCAGGCCGGGATTGCCGGAGAAATC
ATAGGCATTAAAATCGCGCTCAATGAATTTGTGGGCTATATGCAATTTTTACCTTATTTGGGCGATAACCCTCCTTTAAT
CTTGAGCGAGAAAACTAAAGCGATCATCACTTTTGCGTTGTGCGGGTTTGCTAACTTAAGCTCAGTCGCTATGCTTATTG
GGGGGCTTGGCAGTTTGGTGCCTAAAAAGAAAGATCTCATTGTAAGGCTTGCTTTAAAAGCGGTGCTTGTAGGCACGCTT
TCTAATTTCATGAGCGCGACTATCGCTGGGTTATTCATAGGGCTAAACGCTCATTAA

Upstream 100 bases:

>100_bases
TTGATTTAATCTTCATTTAATATCCGTTTAATCTTTTTTTTAGCAAATCTAAACTACAATAACTCTGCATCTTTTAATTT
CTTACATTAGGGATTTGACG

Downstream 100 bases:

>100_bases
AAGGACAAAACATGCAAAAAAGAGTGGTAATCTTATTATTGGATTCTTTTGGTATAGGGGCTAGTGAAGACGCTAGAGAT
TTTGGCGATTTGGGAGCGAA

Product: pyrimidine nucleoside transport protein (nupC)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MIFSSLFSIVGMAVLFLIAWVFSSNKRAINYRTIISAFVIQVALGALALYVPLGREMLQGLASGIQSVIGYGYEGVRFLF
GSLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLKIMPLVINLIGGALQKCLGTSKAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADASVEKHV
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQFLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTL
SNFMSATIAGLFIGLNAH

Sequences:

>Translated_418_residues
MIFSSLFSIVGMAVLFLIAWVFSSNKRAINYRTIISAFVIQVALGALALYVPLGREMLQGLASGIQSVIGYGYEGVRFLF
GSLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLKIMPLVINLIGGALQKCLGTSKAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADASVEKHV
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQFLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTL
SNFMSATIAGLFIGLNAH
>Mature_418_residues
MIFSSLFSIVGMAVLFLIAWVFSSNKRAINYRTIISAFVIQVALGALALYVPLGREMLQGLASGIQSVIGYGYEGVRFLF
GSLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLKIMPLVINLIGGALQKCLGTSKAESMSAAANIFVAHTEAPL
VIKPYLKSMSDSEIFAVMCVGMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADASVEKHV
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLLKPLAFMLGIPWSQAGIAGEI
IGIKIALNEFVGYMQFLPYLGDNPPLILSEKTKAIITFALCGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTL
SNFMSATIAGLFIGLNAH

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI227116277, Length=422, Percent_Identity=34.8341232227488, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI42542381, Length=423, Percent_Identity=34.51536643026, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI11545853, Length=379, Percent_Identity=33.509234828496, Blast_Score=226, Evalue=5e-59,
Organism=Escherichia coli, GI1788485, Length=412, Percent_Identity=45.1456310679612, Blast_Score=324, Evalue=6e-90,
Organism=Escherichia coli, GI1788488, Length=412, Percent_Identity=45.3883495145631, Blast_Score=311, Evalue=7e-86,
Organism=Escherichia coli, GI1788737, Length=405, Percent_Identity=28.1481481481481, Blast_Score=159, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71991794, Length=404, Percent_Identity=31.4356435643564, Blast_Score=194, Evalue=9e-50,
Organism=Caenorhabditis elegans, GI17560276, Length=399, Percent_Identity=31.077694235589, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI25146537, Length=226, Percent_Identity=30.0884955752212, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI45552519, Length=413, Percent_Identity=35.1089588377724, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI45552517, Length=413, Percent_Identity=35.1089588377724, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI19921868, Length=413, Percent_Identity=35.1089588377724, Blast_Score=258, Evalue=7e-69,
Organism=Drosophila melanogaster, GI281360430, Length=408, Percent_Identity=32.5980392156863, Blast_Score=220, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43709; Mature: 43709

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFSSLFSIVGMAVLFLIAWVFSSNKRAINYRTIISAFVIQVALGALALYVPLGREMLQG
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LASGIQSVIGYGYEGVRFLFGSLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLK
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMPLVINLIGGALQKCLGTSKAESMSAAANIFVAHTEAPLVIKPYLKSMSDSEIFAVMCV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEHHHHHCCCCCHHHHHHHH
GMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADASVEKHV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHCHHHHHHHH
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLAFMLGIPWSQAGIAGEIIGIKIALNEFVGYMQFLPYLGDNPPLILSEKTKAIITFAL
HHHHHHHCCCCCCCCCCEEHEEHEEHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
CGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTLSNFMSATIAGLFIGLNAH
HHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIFSSLFSIVGMAVLFLIAWVFSSNKRAINYRTIISAFVIQVALGALALYVPLGREMLQG
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LASGIQSVIGYGYEGVRFLFGSLAPNAKGDQGIGGFIFAINVLAIIIFFASLISLLYYLK
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMPLVINLIGGALQKCLGTSKAESMSAAANIFVAHTEAPLVIKPYLKSMSDSEIFAVMCV
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCEEEHHHHHCCCCCHHHHHHHH
GMASVAGPVLAGYASMGIPLPYLIAASFMSAPGGLLFAKIIYPQNETISSHADASVEKHV
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHCHHHHHHHH
NAIEAIANGASTGLNLALHVGAMLLAFVGMLALINGLLGVVGGFLGMEHLSLGLILGTLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KPLAFMLGIPWSQAGIAGEIIGIKIALNEFVGYMQFLPYLGDNPPLILSEKTKAIITFAL
HHHHHHHCCCCCCCCCCEEHEEHEEHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHH
CGFANLSSVAMLIGGLGSLVPKKKDLIVRLALKAVLVGTLSNFMSATIAGLFIGLNAH
HHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]