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The map label for this gene is deoD

Identifier: 188527966

GI number: 188527966

Start: 1197859

End: 1198563

Strand: Reverse

Name: deoD

Synonym: HPSH_06105

Alternate gene names: 188527966

Gene position: 1198563-1197859 (Counterclockwise)

Preceding gene: 188527967

Following gene: 188527964

Centisome position: 74.51

GC content: 42.84

Gene sequence:

>705_bases
ATGACCCCTCACATCAACGCCAAAATCGGCGATTTTTACCCTCAATGCCTTTTATGTGGCGATCCTTTAAGGGTGAGCTA
CATTGCGAAAAAATTCTTACAAGACGCCAAAGAGATCACGAATGTGCGTAACATGCTAGGCTTTAGCGGGAAGTATAAGG
GTAAGGGGATTTCTTTAATGGGGCATGGCATGGGCATTGCGTCATGCACGATTTATGTAACAGAGCTCATTAAAACCTAT
CAGGTTAAAGAGCTTTTAAGGATTGGCACTTGCGGGGCGATTAGCCCAAAAGTTGGCCTGAAAGACATCATCATGGCGAT
GGGGGCTTCAACGGATTCTAAAACCAATCGGGTGCGTTTTTTAAACCACGATTTGAGTGCGACGCCTGATTTTGAATTGA
GCTTAAGAGCGTATCAAACGGCAAAGCGTTTGGGTATTGATTTGAAAGTGGGCAATGTTTTTTCAAGCGATTTTTTCTAT
TCCTTTGAAACGCATGCCTTTGATTTAATGGTCCAATACAACCACTTGGCTATTGAAATGGAAGCGGCAGGGTTATACGC
CACGGCGATGGAATTGAATGCTAAGGCTTTATGCTTATGCTCGGTTTCAGATCACTTGATCACTAAAGAAGCCTTAAGCC
CTAAAGAAAGGGTAGAAAGCTTTGATAACATGATAATTCTGGCTTTAGAGATGATGACGCAATGA

Upstream 100 bases:

>100_bases
AGAGCGAGTCGTTTGCGGATATTGGGCAAAGCATCGCTTATTTTTTGGGATTAAGCCCCTTAGATTATGGCAAAAACTTA
TTAAACTTTAAAGGACAATC

Downstream 100 bases:

>100_bases
CGATTGAAAAATCATTGTAAATCTTTTTTGATAAAAGCCTTTGATTTTTGTTGGGCTGGATTAGGGGGTTTTGAAGCGTT
AAAACCACGCCTAAAACAAC

Product: purine-nucleoside phosphorylase

Products: NA

Alternate protein names: PNP

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLMGHGMGIASCTIYVTELIKTY
QVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFY
SFETHAFDLMVQYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMTQ

Sequences:

>Translated_234_residues
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLMGHGMGIASCTIYVTELIKTY
QVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFY
SFETHAFDLMVQYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMTQ
>Mature_233_residues
TPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLMGHGMGIASCTIYVTELIKTYQ
VKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRFLNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYS
FETHAFDLMVQYNHLAIEMEAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMTQ

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family

Homologues:

Organism=Escherichia coli, GI1790844, Length=229, Percent_Identity=55.0218340611354, Blast_Score=279, Evalue=1e-76,
Organism=Escherichia coli, GI1790265, Length=190, Percent_Identity=27.8947368421053, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOD_HELPS (B2UUU1)

Other databases:

- EMBL:   CP001072
- RefSeq:   YP_001910653.1
- GeneID:   6297099
- GenomeReviews:   CP001072_GR
- KEGG:   hps:HPSH_06105
- HOGENOM:   HBG617197
- OMA:   SFETHAF
- ProtClustDB:   CLSK496399
- HAMAP:   MF_01627
- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- PANTHER:   PTHR21234
- TIGRFAMs:   TIGR00107

Pfam domain/function: PF01048 PNP_UDP_1

EC number: =2.4.2.1

Molecular weight: Translated: 25959; Mature: 25827

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLM
CCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEE
LNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMVQYNHLAIEM
EECCCCCCCCCEEEHHHHHHHHHHCCEEEECCEECCCEEEEECCCEEEEEEEECEEEEEE
EAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMTQ
ECCCEEEEEEECCCCEEEEEECCCHHHHHHHCCHHHHHHHHHCHHEEEEEHHCC
>Mature Secondary Structure 
TPHINAKIGDFYPQCLLCGDPLRVSYIAKKFLQDAKEITNVRNMLGFSGKYKGKGISLM
CCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEE
GHGMGIASCTIYVTELIKTYQVKELLRIGTCGAISPKVGLKDIIMAMGASTDSKTNRVRF
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEE
LNHDLSATPDFELSLRAYQTAKRLGIDLKVGNVFSSDFFYSFETHAFDLMVQYNHLAIEM
EECCCCCCCCCEEEHHHHHHHHHHCCEEEECCEECCCEEEEECCCEEEEEEEECEEEEEE
EAAGLYATAMELNAKALCLCSVSDHLITKEALSPKERVESFDNMIILALEMMTQ
ECCCEEEEEEECCCCEEEEEECCCHHHHHHHCCHHHHHHHHHCHHEEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA