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The map label for this gene is murG

Identifier: 188527939

GI number: 188527939

Start: 1170248

End: 1171309

Strand: Direct

Name: murG

Synonym: HPSH_05960

Alternate gene names: 188527939

Gene position: 1170248-1171309 (Clockwise)

Preceding gene: 188527938

Following gene: 188527940

Centisome position: 72.75

GC content: 41.43

Gene sequence:

>1062_bases
ATGAAATTCGCTCTCACAGGGGGAGGCACAGGCGGGCATCTCTCTATCGCTAAAGCCTTAGCCATAGAATTAGAAAAGCA
AGGCATAGAGGCTATTTATTTAGGCTCAACTTATGGGCAAGATAAGGAATGGTTTGAAAATAGCCCCCTATTTAGCGAAC
GCTATTTTTTCAACACGCAAGGCGTGGTCAATAAAAGCTTTTTTAAAAAAATAGGCTCTTTATTCTTGCAAGCTAAAGCC
GCATTTAAGGCTAAAGAAATCTTAAAAAAACACCAGATCACGCACACCATTAGCGTGGGAGGGTTTAGTGCAGGGCCTGC
AAGTTTTGCAAGCTTACTCAATAAAATACCCCTTTATATCCATGAGCAAAATGCGATTAAAGGCTCTCTTAATCGCTACC
TTTCCCCTAAAGCTAAGGCGGTGTTTTCAAGCTATGCCTTTAAAGATAAAGGAAATCATGTTTTAACCTCCTATCCCGTG
CAAAACGCTTTTTTTGATTTTGCTAGGACTCGCACGGAAATCAAGCATATTTTATTTTTAGGCGGTTCGCAAGGGGCAAA
AGCGATCAATGAATTCGCTTTATTAAACGCTCCTAAACTCACCAAACAAGGGATTAAGATCACGCATATTTGCGGCTCAG
ACGCTCATGAAAGAATGCGTTTTTTTTACCAAGAATTGGGGCTGTTGGATAAGGTAGAATTGTTCGCTTTCCACAACAAC
ATCACAGAAGTCATGCACAGGGCGGATTTGTGTGTGAGCCGAGCCGGAGCGAGCAGCGTGTGGGAATTGTGCGCCAATGG
CTTACCCACGATTTTTATCCCCTACCCTTTTGCGAGCAATAACCACCAGTATTACAATGTCTTAGAATTTGAAAAAGAAA
ACCTATGCTATGTCGTGCCTCAAAACGAATTATTGCCTAAAAAACTCTTTGAAGTCATTAGAAAGCTCAACCAAAAAGAC
GATCAAGGCAATAAAAACCTCACCACTATCAGCAACCAATTGCAACAAAAAATCGCTAAAGACGGCGCAAAAACCATCAT
TGAAACGATTTTGAGCGCCTAA

Upstream 100 bases:

>100_bases
AAGTCGCGCTTTCTATGATGGATTATCCGGATTTTGGCTTTAGAGATCCTTTAAAAAGCTTTGTGATTCAAGAAAGAGAA
CGAGCTTAAGGGTTTTTAAC

Downstream 100 bases:

>100_bases
AATAGCCCATTTTAATCAACAATTAAGCGACCAACCATTAAACTTAAGCGATAAATAAGATAAAATTTAGGATAACTCAA
ATCTTTTAAAAAGAAAAGGA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKA
AFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPV
QNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGSDAHERMRFFYQELGLLDKVELFAFHNN
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVPQNELLPKKLFEVIRKLNQKD
DQGNKNLTTISNQLQQKIAKDGAKTIIETILSA

Sequences:

>Translated_353_residues
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKA
AFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPV
QNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGSDAHERMRFFYQELGLLDKVELFAFHNN
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVPQNELLPKKLFEVIRKLNQKD
DQGNKNLTTISNQLQQKIAKDGAKTIIETILSA
>Mature_353_residues
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKA
AFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPV
QNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGSDAHERMRFFYQELGLLDKVELFAFHNN
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVPQNELLPKKLFEVIRKLNQKD
DQGNKNLTTISNQLQQKIAKDGAKTIIETILSA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=311, Percent_Identity=27.0096463022508, Blast_Score=115, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39456; Mature: 39456

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCC
GVVNKSFFKKIGSLFLQAKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEE
HEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPVQNAFFDFARTRTEIKHILFL
ECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEE
GGSQGAKAINEFALLNAPKLTKQGIKITHICGSDAHERMRFFYQELGLLDKVELFAFHNN
CCCCCHHHHHHHHHCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEEC
QNELLPKKLFEVIRKLNQKDDQGNKNLTTISNQLQQKIAKDGAKTIIETILSA
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQ
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCCCCCCCCEEECCC
GVVNKSFFKKIGSLFLQAKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCEEE
HEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGNHVLTSYPVQNAFFDFARTRTEIKHILFL
ECCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHEEEEE
GGSQGAKAINEFALLNAPKLTKQGIKITHICGSDAHERMRFFYQELGLLDKVELFAFHNN
CCCCCHHHHHHHHHCCCCCHHHCCCEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVVP
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEEECCCCEEEEEC
QNELLPKKLFEVIRKLNQKDDQGNKNLTTISNQLQQKIAKDGAKTIIETILSA
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA