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The map label for this gene is pgl [H]

Identifier: 188527881

GI number: 188527881

Start: 1116592

End: 1117275

Strand: Direct

Name: pgl [H]

Synonym: HPSH_05660

Alternate gene names: 188527881

Gene position: 1116592-1117275 (Clockwise)

Preceding gene: 188527880

Following gene: 188527882

Centisome position: 69.42

GC content: 39.33

Gene sequence:

>684_bases
ATGGGTTATCAATTGTTTGAATTTGAAAATTTAGAAAATTGCCACAAGGCTTTAACAGAGCGTTTTAAAGAATTTTTTAA
CGCCACCTTAAAAAAGCACCATCAAGTTTCTATCGCTTTTTCTGGGGGCCGTTCGCCCATTGGTTTGTTGCAAAAATTGA
GCGTTTTAGATCTCAAATGGCATGCGTGTTTAGTCAGTTTGGTGGATGAGCGCATTATAGACACAAATCATGATGATAGC
AACACCAAATTATTGCGCGACTACTTGTTGCAAAATAACGCCTTAAAAGCTTCTTTCATCCCGCTTTTGCCTGAAAAGAT
TTCTAACGATACAAACGCGCTTTTTAATTTTGCTAACCAGCATTTCAAACAGCCCCATTTAGCCATTTTGGGCATGGGGA
CTGACGGGCATACGGCTAGCCTTTTTCCTGAAACGAGCGCTTTTTTAAACGAAGAAAAAGAAAATATCGTCTTAGTTAAG
CCAGCTAACGCTCCTTATGAGCGCTTGAGCATGTCTATTAACGCCTTAGAAAATTGCGAAAAACTTTTCTTAAGCATTAG
CGGAGCGCAAAAAAGGGGAGTTTTAGAAAACGCTTTAAAAGAAAACGCTCCCTATTCTCTGCCGATTGCTCGGATTTTAC
ATTCTCAAAAAGTTACCACGGAGGTGTTTTATGCCAAAAACTGA

Upstream 100 bases:

>100_bases
GAAGGTTTTATGAATAACGCCACGCCCTTATATTCCTATGAAAGCCACAATCTAAACGAATCCGAATTTTTAAAACCACT
CTATCAATGAAAGGGATTTC

Downstream 100 bases:

>100_bases
AACTTACCCAAGACTATTAGCCGATATTGGCGGCACGAACGCGCGCTTTGGCTTAGAAGTCGCCCCACGACAGATTGAAT
GCATTGAAGTCTTGCCATGC

Product: glucose-6-phosphate 1-dehydrogenase (devB)

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MGYQLFEFENLENCHKALTERFKEFFNATLKKHHQVSIAFSGGRSPIGLLQKLSVLDLKWHACLVSLVDERIIDTNHDDS
NTKLLRDYLLQNNALKASFIPLLPEKISNDTNALFNFANQHFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLVK
PANAPYERLSMSINALENCEKLFLSISGAQKRGVLENALKENAPYSLPIARILHSQKVTTEVFYAKN

Sequences:

>Translated_227_residues
MGYQLFEFENLENCHKALTERFKEFFNATLKKHHQVSIAFSGGRSPIGLLQKLSVLDLKWHACLVSLVDERIIDTNHDDS
NTKLLRDYLLQNNALKASFIPLLPEKISNDTNALFNFANQHFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLVK
PANAPYERLSMSINALENCEKLFLSISGAQKRGVLENALKENAPYSLPIARILHSQKVTTEVFYAKN
>Mature_226_residues
GYQLFEFENLENCHKALTERFKEFFNATLKKHHQVSIAFSGGRSPIGLLQKLSVLDLKWHACLVSLVDERIIDTNHDDSN
TKLLRDYLLQNNALKASFIPLLPEKISNDTNALFNFANQHFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLVKP
ANAPYERLSMSINALENCEKLFLSISGAQKRGVLENALKENAPYSLPIARILHSQKVTTEVFYAKN

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=208, Percent_Identity=29.3269230769231, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25613; Mature: 25481

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYQLFEFENLENCHKALTERFKEFFNATLKKHHQVSIAFSGGRSPIGLLQKLSVLDLKW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHH
HACLVSLVDERIIDTNHDDSNTKLLRDYLLQNNALKASFIPLLPEKISNDTNALFNFANQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHCCHHHHHHHHHHH
HFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLVKPANAPYERLSMSINALENCE
HCCCCCEEEEEECCCCCCEECCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KLFLSISGAQKRGVLENALKENAPYSLPIARILHSQKVTTEVFYAKN
HHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHEEEEEECC
>Mature Secondary Structure 
GYQLFEFENLENCHKALTERFKEFFNATLKKHHQVSIAFSGGRSPIGLLQKLSVLDLKW
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHH
HACLVSLVDERIIDTNHDDSNTKLLRDYLLQNNALKASFIPLLPEKISNDTNALFNFANQ
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHCCCCHHHHCCHHHHHHHHHHH
HFKQPHLAILGMGTDGHTASLFPETSAFLNEEKENIVLVKPANAPYERLSMSINALENCE
HCCCCCEEEEEECCCCCCEECCCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
KLFLSISGAQKRGVLENALKENAPYSLPIARILHSQKVTTEVFYAKN
HHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]