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The map label for this gene is xseA

Identifier: 188527802

GI number: 188527802

Start: 1027745

End: 1028107

Strand: Reverse

Name: xseA

Synonym: HPSH_05210

Alternate gene names: 188527802

Gene position: 1028107-1027745 (Counterclockwise)

Preceding gene: 188527803

Following gene: 188527801

Centisome position: 63.92

GC content: 40.5

Gene sequence:

>363_bases
ATGGACACTATTTGTTTAAAAGAAGGGCAGGAAGTGGTTGTTTTTGGGGGCATTAGCGCGTATGTTCCAAGGGGGGATTA
TCAAATCAATTGCTTTGAAATAGAGCCTAAAGATATAGGTTCATTAACCCTAGCTTTAGAGCAATTGAAAGAAAAATTAC
GCCTTAACACAAAAAACGCTTTTGATGCGATTGTGGTGGCTAGGGGTGGGGGGAGCATAGAAGATTTGTATCCTTTCAAT
GATGAGAAAATCGCTGATGCATTGCATTTGGCTAAAACTTTCAGCATGTCAGCTATTGGGCATGAGAGCGATTTTTTATT
GAGCGATTTGGTAGCGGATTTAAGGGCTTCTACGCCTTTTTGA

Upstream 100 bases:

>100_bases
GCAAGCGGTGGGGTATGATGTTCATTGTAGCGGTTTTAATGCTGGCGTTTATCGCTCAAGCGAATGATAGTTATGTGCAA
AAAAGCCCTTTTTAAAAGCT

Downstream 100 bases:

>100_bases
ACCTGGAAGTCAAGCTCTTCATCGCTGATAATACTGCTCTTTTCAAGAGTGGGAATGCAGGTCGGTGCAGGGATAGGGAA
ATGTTTTAGTCTTGCTTTTT

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MDTICLKEGQEVVVFGGISAYVPRGDYQINCFEIEPKDIGSLTLALEQLKEKLRLNTKNAFDAIVVARGGGSIEDLYPFN
DEKIADALHLAKTFSMSAIGHESDFLLSDLVADLRASTPF

Sequences:

>Translated_120_residues
MDTICLKEGQEVVVFGGISAYVPRGDYQINCFEIEPKDIGSLTLALEQLKEKLRLNTKNAFDAIVVARGGGSIEDLYPFN
DEKIADALHLAKTFSMSAIGHESDFLLSDLVADLRASTPF
>Mature_120_residues
MDTICLKEGQEVVVFGGISAYVPRGDYQINCFEIEPKDIGSLTLALEQLKEKLRLNTKNAFDAIVVARGGGSIEDLYPFN
DEKIADALHLAKTFSMSAIGHESDFLLSDLVADLRASTPF

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=64, Percent_Identity=51.5625, Blast_Score=79, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 13139; Mature: 13139

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTICLKEGQEVVVFGGISAYVPRGDYQINCFEIEPKDIGSLTLALEQLKEKLRLNTKNA
CCCCCCCCCCEEEEECCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
FDAIVVARGGGSIEDLYPFNDEKIADALHLAKTFSMSAIGHESDFLLSDLVADLRASTPF
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDTICLKEGQEVVVFGGISAYVPRGDYQINCFEIEPKDIGSLTLALEQLKEKLRLNTKNA
CCCCCCCCCCEEEEECCCEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
FDAIVVARGGGSIEDLYPFNDEKIADALHLAKTFSMSAIGHESDFLLSDLVADLRASTPF
CEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA