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The map label for this gene is queD [H]

Identifier: 188527755

GI number: 188527755

Start: 975402

End: 976004

Strand: Direct

Name: queD [H]

Synonym: HPSH_04910

Alternate gene names: 188527755

Gene position: 975402-976004 (Clockwise)

Preceding gene: 188527754

Following gene: 188527756

Centisome position: 60.64

GC content: 38.31

Gene sequence:

>603_bases
ATGGTTATCAGGCGATTGTATAAATTTTGCGCTAGCCATGTGGTGCGCAATTGCTCTTCTTTAAAATGCGCTCAAAATAT
CCATGGGCATAATTATGAAGTGGAGGTTTTTATTGAAACCAACCGCTTAGACAGCGCGAACATGGCGTTAGATTTTGGGC
TGATGCAACAAGAAATGCAAGTTTTCATTGAGTCGTTTGATCATGCCCATCATTTTTGGGACAAAGAAAGCGATGAGTTT
CAGCGTTTTATAGAAAATCATTGCGTTCGTTATGTGAAATGCTCGTTCAATTTGAGCGCAGAGAGTTACGCTCTCATGTT
TTTATACTACCTGACAAAGATCTTACAAAAAAGCGTTTTTTCCAATAACGAAGGGGAGTTAAAAATCTCTAGCGTGCGCG
TGCATGAGACTAAAAACGGCTATGCGGAGAGCTTTTTAAAAGATTTAGAAAACCCACACTTTAAATCTTTAGTGCATAAT
TGTTGCGTTTCTTTCTCACAAGGCATTCAAAATTTGTGGCATGATAAGGATTTTTTTAATAAAATCATTAGCGATGAAAA
ACAATGCTTTTTCCACGCTAAGCCCCTACACCAGATCCCATGA

Upstream 100 bases:

>100_bases
GATTAAAAGCACGATCAAGCGCATTGATTTTAACCGCCCTGAACGCTACTATTATAATTTAAGACTGCCCCTTTATCAGC
CATGTTATAGGCAATGAGCA

Downstream 100 bases:

>100_bases
AACTCCCGGTCGTTGAGAGCTTTTTTTCCTTACAAGGTGAAGGAAAAAGGATAGGCAAACCCAGTCTTTTTTTGCGCTTA
GGGGGGTGTAATCTTTCATG

Product: hypothetical protein

Products: NA

Alternate protein names: CPH4 synthase; Queuosine biosynthesis protein queD [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDSANMALDFGLMQQEMQVFIESFDHAHHFWDKESDEF
QRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVFSNNEGELKISSVRVHETKNGYAESFLKDLENPHFKSLVHN
CCVSFSQGIQNLWHDKDFFNKIISDEKQCFFHAKPLHQIP

Sequences:

>Translated_200_residues
MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDSANMALDFGLMQQEMQVFIESFDHAHHFWDKESDEF
QRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVFSNNEGELKISSVRVHETKNGYAESFLKDLENPHFKSLVHN
CCVSFSQGIQNLWHDKDFFNKIISDEKQCFFHAKPLHQIP
>Mature_200_residues
MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDSANMALDFGLMQQEMQVFIESFDHAHHFWDKESDEF
QRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVFSNNEGELKISSVRVHETKNGYAESFLKDLENPHFKSLVHN
CCVSFSQGIQNLWHDKDFFNKIISDEKQCFFHAKPLHQIP

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 23616; Mature: 23616

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDSANMALDFGLMQQEMQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHH
VFIESFDHAHHFWDKESDEFQRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
SNNEGELKISSVRVHETKNGYAESFLKDLENPHFKSLVHNCCVSFSQGIQNLWHDKDFFN
CCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KIISDEKQCFFHAKPLHQIP
HHHCCCHHHEEECCCCCCCC
>Mature Secondary Structure
MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDSANMALDFGLMQQEMQ
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHH
VFIESFDHAHHFWDKESDEFQRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVF
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHH
SNNEGELKISSVRVHETKNGYAESFLKDLENPHFKSLVHNCCVSFSQGIQNLWHDKDFFN
CCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHH
KIISDEKQCFFHAKPLHQIP
HHHCCCHHHEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]