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The map label for this gene is gapA [H]

Identifier: 188527745

GI number: 188527745

Start: 960014

End: 961009

Strand: Direct

Name: gapA [H]

Synonym: HPSH_04850

Alternate gene names: 188527745

Gene position: 960014-961009 (Clockwise)

Preceding gene: 188527739

Following gene: 188527746

Centisome position: 59.68

GC content: 41.67

Gene sequence:

>996_bases
ATGAAAATTTTTATCAATGGATTTGGCCGCATTGGGAGATGCGTTTTAAGAGCGATTTTAGAGCGTAGCGATAACCCTCA
CTTAGAAGTGATAGGCATCAATGACCCTGCTAATTGGGAAATCCTCGCTTATCTTTTAGAGCATGACAGCGCGCATGGGC
TGCTCAATAAAGAGGCGCGTTATTCTAATGGTAAGCTTATTATCGGCTCGTTAGAAATCCCTGTTTTTAATAGCATCAAA
GACTTGAAAGGCGTGGATGTCATCATAGAGTGTTCAGGGAAGTTTTTAGAGCCTAAAACGCTGGAAAATTATCTTTTGCT
TGGGGCTAAAAAGGTTCTGTTATCCGCTCCCTTTATAGGCGAATACGATGAAAAACAATACCCTACTTTGGTGTATGGGG
TCAATCACTCTCTCTATCAAAACCAGGCCATTGTTTCTAACGCCTCTTGCACGACTAACGCTATCGCGCCCATTTGCGCG
ATTTTAGATAAAGCTTTTGGCATTAAAGAGGGCATGCTAACGACCATTCATAGTTATACAAGCGATCAAAAACTCATTGA
TTTGGCCCACCCTTTGGACAAACGGCGCTCAAGAGCGGCTGCAAGCAACATTATCCCTACCACCACTAAAGCCGCTCTGG
CCTTGCATAAAGTTTTACCCAATCTCAAAAACAAAATGCATGGGCATAGCGTGAGGGTGCCTAGCCTTGATGTGTCCATG
ATAGATTTGAGTTTGTTTTTAGAAAAAAAGGCCCCTAAAGATCCCATCAATGGTTTATTGATTGAAGCTTCCAAAGGGGT
TTTAAAAGGCGTGTTAGAGATAGATTTAAAAGAAAGGGTGAGTTCTGATTTCATTTCTAACCCTAGTAGCGTCATAATCG
CGCCTGATTTGACTTTCACGCTAGAGAATATGGTCAAAATCATGGGGTGGTATGATAATGAATGGGGGTATTCTCATCGT
TTGGTGGATATGGCGCAATTTATGTATCATTATTAA

Upstream 100 bases:

>100_bases
CCTACAGCTAGGTTCAATATAATAGCGCAAAATGTAGTAAAATACCAAACAAAACCCCCTAAAATTGAAATTGAAGTCTG
AAAATAGGATAATGGTTACG

Downstream 100 bases:

>100_bases
GTCATTTTGCGAATCTTTTTGAGCTTGTTTAACATCAAGTTGTATAATGTGGGATTTATAAAAACGATCGGAGTTTAAAT
GGCGTTTAAAAAGGCTGGAT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKIFINGFGRIGRCVLRAILERSDNPHLEVIGINDPANWEILAYLLEHDSAHGLLNKEARYSNGKLIIGSLEIPVFNSIK
DLKGVDVIIECSGKFLEPKTLENYLLLGAKKVLLSAPFIGEYDEKQYPTLVYGVNHSLYQNQAIVSNASCTTNAIAPICA
ILDKAFGIKEGMLTTIHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSM
IDLSLFLEKKAPKDPINGLLIEASKGVLKGVLEIDLKERVSSDFISNPSSVIIAPDLTFTLENMVKIMGWYDNEWGYSHR
LVDMAQFMYHY

Sequences:

>Translated_331_residues
MKIFINGFGRIGRCVLRAILERSDNPHLEVIGINDPANWEILAYLLEHDSAHGLLNKEARYSNGKLIIGSLEIPVFNSIK
DLKGVDVIIECSGKFLEPKTLENYLLLGAKKVLLSAPFIGEYDEKQYPTLVYGVNHSLYQNQAIVSNASCTTNAIAPICA
ILDKAFGIKEGMLTTIHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSM
IDLSLFLEKKAPKDPINGLLIEASKGVLKGVLEIDLKERVSSDFISNPSSVIIAPDLTFTLENMVKIMGWYDNEWGYSHR
LVDMAQFMYHY
>Mature_331_residues
MKIFINGFGRIGRCVLRAILERSDNPHLEVIGINDPANWEILAYLLEHDSAHGLLNKEARYSNGKLIIGSLEIPVFNSIK
DLKGVDVIIECSGKFLEPKTLENYLLLGAKKVLLSAPFIGEYDEKQYPTLVYGVNHSLYQNQAIVSNASCTTNAIAPICA
ILDKAFGIKEGMLTTIHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSM
IDLSLFLEKKAPKDPINGLLIEASKGVLKGVLEIDLKERVSSDFISNPSSVIIAPDLTFTLENMVKIMGWYDNEWGYSHR
LVDMAQFMYHY

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=339, Percent_Identity=38.6430678466077, Blast_Score=242, Evalue=4e-64,
Organism=Homo sapiens, GI7669492, Length=337, Percent_Identity=38.8724035608309, Blast_Score=229, Evalue=2e-60,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=40.1812688821752, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1789295, Length=336, Percent_Identity=38.6904761904762, Blast_Score=234, Evalue=8e-63,
Organism=Caenorhabditis elegans, GI17534677, Length=342, Percent_Identity=40.3508771929825, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17534679, Length=342, Percent_Identity=40.0584795321637, Blast_Score=238, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI32566163, Length=342, Percent_Identity=38.5964912280702, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17568413, Length=342, Percent_Identity=38.5964912280702, Blast_Score=228, Evalue=5e-60,
Organism=Saccharomyces cerevisiae, GI6322409, Length=338, Percent_Identity=40.5325443786982, Blast_Score=246, Evalue=4e-66,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=39.8809523809524, Blast_Score=237, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=39.4029850746269, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=39.4658753709199, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=39.4658753709199, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=39.4658753709199, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=39.4658753709199, Blast_Score=225, Evalue=4e-59,
Organism=Drosophila melanogaster, GI19922412, Length=334, Percent_Identity=40.4191616766467, Blast_Score=224, Evalue=5e-59,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36829; Mature: 36829

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIFINGFGRIGRCVLRAILERSDNPHLEVIGINDPANWEILAYLLEHDSAHGLLNKEAR
CEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
YSNGKLIIGSLEIPVFNSIKDLKGVDVIIECSGKFLEPKTLENYLLLGAKKVLLSAPFIG
CCCCCEEEEEECCCCHHCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
EYDEKQYPTLVYGVNHSLYQNQAIVSNASCTTNAIAPICAILDKAFGIKEGMLTTIHSYT
CCCCCCCCEEEEECCCHHHCCCHHEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
SDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSM
CCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHH
IDLSLFLEKKAPKDPINGLLIEASKGVLKGVLEIDLKERVSSDFISNPSSVIIAPDLTFT
HHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
LENMVKIMGWYDNEWGYSHRLVDMAQFMYHY
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIFINGFGRIGRCVLRAILERSDNPHLEVIGINDPANWEILAYLLEHDSAHGLLNKEAR
CEEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCC
YSNGKLIIGSLEIPVFNSIKDLKGVDVIIECSGKFLEPKTLENYLLLGAKKVLLSAPFIG
CCCCCEEEEEECCCCHHCHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
EYDEKQYPTLVYGVNHSLYQNQAIVSNASCTTNAIAPICAILDKAFGIKEGMLTTIHSYT
CCCCCCCCEEEEECCCHHHCCCHHEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHCC
SDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSM
CCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCHHH
IDLSLFLEKKAPKDPINGLLIEASKGVLKGVLEIDLKERVSSDFISNPSSVIIAPDLTFT
HHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHH
LENMVKIMGWYDNEWGYSHRLVDMAQFMYHY
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]