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The map label for this gene is engD [H]

Identifier: 188527584

GI number: 188527584

Start: 786425

End: 787525

Strand: Direct

Name: engD [H]

Synonym: HPSH_04030

Alternate gene names: 188527584

Gene position: 786425-787525 (Clockwise)

Preceding gene: 188527583

Following gene: 188527585

Centisome position: 48.89

GC content: 41.42

Gene sequence:

>1101_bases
ATGGGCTTGTCTGTAGGCATTGTGGGTTTGCCTAATGTGGGCAAATCCAGCACCTTTAACGCGCTCACTAAAACCCAAAA
CGCAGAGAGCGCGAACTACCCTTTTTGCACCATTGAACCCAATAAAGCCATCGTGAATGTGCCTGATAGGCGGCTTGATG
CGTTGGCTCAAATCGTAAAGCCTGAACGCATTTTGCATTCTGTGGTGGAATTTGTGGATATTGCCGGGTTGATTAAGGGA
GCGAGCAAGGGGGAGGGTTTAGGCAATCAATTTTTAGCCAATATCAAGGAATGCGAAGTGATCTTGCAAGTGGTGCGCTG
TTTTGAAGATGACAATGTCACGCATGTGAATGATAAAATTGACCCCCTAAATGATATAGAGATCATTGAATTGGAGTTGA
TTTTAGCGGATATTGCCACTTTAGACAAAAGGATCGATCGCTTGCAAAAAGCCCTAAAAAGCTCAAAAGACGCTAAAAAT
CTTTTAGAATGCGCTTTGAGTTTAAAAACGCATTTAGAAGAATTAAAGCCGGCGAAAACTTTTCCCTTGAATGCGAGCGA
GGCTTTTTTAGAATTGGACAAGGAATTGCGCTTTTTATCTAATAAAAAAATGATCTATGCCGCTAATGTGGGCGAAGAAG
ATTTAAACGCTCTCAATGAGCATGCTAAAAAAGTCCAAAATTATGCGAAAGATCAAAATAGCGAGTTTGTTGCCTTGTGC
GCTAAATTAGAAGAAGAAATGGTTTCTATGAGTGAAGATGAAGTCAAAGAATTTTTGCAAAGTTTAGGCGTAGAAGAAAG
CGGGCTAGAAAAGACCATTCGTTTGAGTTTTAAGGAATTAGGCTTGATCAATTACTTTACCGCTGGAGTCAAGGAAGTGC
GATCATGGACCATTAAAAAAGGCTCTAGTGCGCCTGTGGCTGCTGGGGTGATCCATAAGGATTTTGAAAAAGGCTTTATC
AGAGCTGAAACCATCAGTTATGATGATTTTATCGCTTATAAGGGCGAAGCCGGAGCGAAAGAAAAGGGAGCGTTACGCAT
TGAAGGTAAGGATTATATCGTTCAAGATGGCGATGTGTTGCATTTTCGCTTCAATGTCTAG

Upstream 100 bases:

>100_bases
TATGTGGAAAAAGAATGGGATGTGAATAGCTTTGGAGCGAGTGGGGCTGGGGTTAGGGCTTGCACAGCTTTTGTGGAAGA
ATTTTTGAAAAAGGCTTGAA

Downstream 100 bases:

>100_bases
TGTCTTTTCAAACAAGCGTTACTATTTTCTGAATTGACACCCAGTAAGAAACTTTTTAAAAAGATCTATATAGAGTTAAG
CGATATTTGCGGGTTGCAAT

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MGLSVGIVGLPNVGKSSTFNALTKTQNAESANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILHSVVEFVDIAGLIKG
ASKGEGLGNQFLANIKECEVILQVVRCFEDDNVTHVNDKIDPLNDIEIIELELILADIATLDKRIDRLQKALKSSKDAKN
LLECALSLKTHLEELKPAKTFPLNASEAFLELDKELRFLSNKKMIYAANVGEEDLNALNEHAKKVQNYAKDQNSEFVALC
AKLEEEMVSMSEDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKKGSSAPVAAGVIHKDFEKGFI
RAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVLHFRFNV

Sequences:

>Translated_366_residues
MGLSVGIVGLPNVGKSSTFNALTKTQNAESANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILHSVVEFVDIAGLIKG
ASKGEGLGNQFLANIKECEVILQVVRCFEDDNVTHVNDKIDPLNDIEIIELELILADIATLDKRIDRLQKALKSSKDAKN
LLECALSLKTHLEELKPAKTFPLNASEAFLELDKELRFLSNKKMIYAANVGEEDLNALNEHAKKVQNYAKDQNSEFVALC
AKLEEEMVSMSEDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKKGSSAPVAAGVIHKDFEKGFI
RAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVLHFRFNV
>Mature_365_residues
GLSVGIVGLPNVGKSSTFNALTKTQNAESANYPFCTIEPNKAIVNVPDRRLDALAQIVKPERILHSVVEFVDIAGLIKGA
SKGEGLGNQFLANIKECEVILQVVRCFEDDNVTHVNDKIDPLNDIEIIELELILADIATLDKRIDRLQKALKSSKDAKNL
LECALSLKTHLEELKPAKTFPLNASEAFLELDKELRFLSNKKMIYAANVGEEDLNALNEHAKKVQNYAKDQNSEFVALCA
KLEEEMVSMSEDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKKGSSAPVAAGVIHKDFEKGFIR
AETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVLHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=370, Percent_Identity=41.8918918918919, Blast_Score=280, Evalue=1e-75,
Organism=Homo sapiens, GI58761502, Length=228, Percent_Identity=35.5263157894737, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24308117, Length=113, Percent_Identity=34.5132743362832, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=54.7683923705722, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1789574, Length=167, Percent_Identity=32.3353293413174, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=368, Percent_Identity=41.5760869565217, Blast_Score=278, Evalue=4e-75,
Organism=Saccharomyces cerevisiae, GI6319499, Length=374, Percent_Identity=39.0374331550802, Blast_Score=233, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=34.9869451697128, Blast_Score=196, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6321649, Length=165, Percent_Identity=36.969696969697, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=41.0326086956522, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=41.0326086956522, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=41.0326086956522, Blast_Score=266, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=38.9570552147239, Blast_Score=215, Evalue=4e-56,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 40593; Mature: 40462

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLSVGIVGLPNVGKSSTFNALTKTQNAESANYPFCTIEPNKAIVNVPDRRLDALAQIVK
CCCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHC
PERILHSVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNVTHVNDKI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLNDIEIIELELILADIATLDKRIDRLQKALKSSKDAKNLLECALSLKTHLEELKPAKT
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
FPLNASEAFLELDKELRFLSNKKMIYAANVGEEDLNALNEHAKKVQNYAKDQNSEFVALC
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKLEEEMVSMSEDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKK
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVL
CCCCCHHHHHHHHHHHHCCEEEEEECCCHHEEECCCCCCCCCCEEEECCCEEEEECCCEE
HFRFNV
EEEECC
>Mature Secondary Structure 
GLSVGIVGLPNVGKSSTFNALTKTQNAESANYPFCTIEPNKAIVNVPDRRLDALAQIVK
CCEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCCCEEECCHHHHHHHHHHHC
PERILHSVVEFVDIAGLIKGASKGEGLGNQFLANIKECEVILQVVRCFEDDNVTHVNDKI
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCC
DPLNDIEIIELELILADIATLDKRIDRLQKALKSSKDAKNLLECALSLKTHLEELKPAKT
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
FPLNASEAFLELDKELRFLSNKKMIYAANVGEEDLNALNEHAKKVQNYAKDQNSEFVALC
CCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
AKLEEEMVSMSEDEVKEFLQSLGVEESGLEKTIRLSFKELGLINYFTAGVKEVRSWTIKK
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSSAPVAAGVIHKDFEKGFIRAETISYDDFIAYKGEAGAKEKGALRIEGKDYIVQDGDVL
CCCCCHHHHHHHHHHHHCCEEEEEECCCHHEEECCCCCCCCCCEEEECCCEEEEECCCEE
HFRFNV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]