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The map label for this gene is serB [C]

Identifier: 188527499

GI number: 188527499

Start: 691959

End: 692582

Strand: Direct

Name: serB [C]

Synonym: HPSH_03595

Alternate gene names: 188527499

Gene position: 691959-692582 (Clockwise)

Preceding gene: 188527498

Following gene: 188527500

Centisome position: 43.02

GC content: 41.19

Gene sequence:

>624_bases
GTGCAAAAACTAGCCGTTTTTGATTTTGACTCCACGCTAGTCAATGCTGAGACGATTGAGTCTTTAGCGAGGGCGTGGGG
GGTTTTTGATGAAGTGAGAAAAATCACTTCACAAGCCATGAATGGCGAAACAGATTTTCATAAAAGTCTTATTTTAAGGG
TTTCTAAACTCAAAAACATGCCCTTAAAACTAGCCAAAGAAGTTTGTGAAAGTCTGCCTTTATTTGAAGGAGCGCTTGAG
CTTGTTAGCGCCTTAAAAGAGAAAAATTATAAGGTGGTTTGCTTCAGCGGGGGCTTTGATCTAGCGACGAATTATTATAG
GGATTTATTAAAATTAGATGCGGCTTTCAGTAACACGCTGATAGTGGAAAATGACGCCTTAAACGGCTTGGTTACGGGGC
ATATGATGTTTTCACACTCTAAAGGCGAAATGCTTCTCGCCCTACAACGCTTGTTAAATATCAGTAAAACGAACACTTTA
GTCGTGGGCGATGGGGCGAATGACTTGAGCATGTTCAAACATGCCCGCATTAAAATCGCTTTCAACGCTAAAGAGGTTTT
AAAACAGCACGCCACGCATTGCATCAATGAGCCTGATTTAGCCCTAATCAAGCCTTTGATTTAA

Upstream 100 bases:

>100_bases
AATTGAGTTGATTGGTAATGAAAACCATGGCTTGTATTTGGCCGATCAGTATGTCAAAGGGATCGCTAAAAGCAGGAAAT
CTTAATTTTAGGGTCATTGA

Downstream 100 bases:

>100_bases
AAAATTTTTTTTGTAAAATACTCCTTTAAACCATAAGGATAAGAGAATGTTCCAACCCTTACTAGACGCCTTCATAGAAA
GCGCTTCAATTAAAAAAAAA

Product: phosphoserine phosphatase (serB)

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVRKITSQAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGALE
LVSALKEKNYKVVCFSGGFDLATNYYRDLLKLDAAFSNTLIVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKTNTL
VVGDGANDLSMFKHARIKIAFNAKEVLKQHATHCINEPDLALIKPLI

Sequences:

>Translated_207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVRKITSQAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGALE
LVSALKEKNYKVVCFSGGFDLATNYYRDLLKLDAAFSNTLIVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKTNTL
VVGDGANDLSMFKHARIKIAFNAKEVLKQHATHCINEPDLALIKPLI
>Mature_207_residues
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVRKITSQAMNGETDFHKSLILRVSKLKNMPLKLAKEVCESLPLFEGALE
LVSALKEKNYKVVCFSGGFDLATNYYRDLLKLDAAFSNTLIVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKTNTL
VVGDGANDLSMFKHARIKIAFNAKEVLKQHATHCINEPDLALIKPLI

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=188, Percent_Identity=30.8510638297872, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI1790849, Length=197, Percent_Identity=37.0558375634518, Blast_Score=122, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321647, Length=195, Percent_Identity=38.974358974359, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 23028; Mature: 23028

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVRKITSQAMNGETDFHKSLILRVSKLKNM
CCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
PLKLAKEVCESLPLFEGALELVSALKEKNYKVVCFSGGFDLATNYYRDLLKLDAAFSNTL
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCE
IVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKTNTLVVGDGANDLSMFKHARIKIA
EEECCCCCHHEEHHHEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHEEEE
FNAKEVLKQHATHCINEPDLALIKPLI
ECHHHHHHHHHHHCCCCCCHHHHCCCC
>Mature Secondary Structure
MQKLAVFDFDSTLVNAETIESLARAWGVFDEVRKITSQAMNGETDFHKSLILRVSKLKNM
CCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
PLKLAKEVCESLPLFEGALELVSALKEKNYKVVCFSGGFDLATNYYRDLLKLDAAFSNTL
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCE
IVENDALNGLVTGHMMFSHSKGEMLLALQRLLNISKTNTLVVGDGANDLSMFKHARIKIA
EEECCCCCHHEEHHHEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHEEEE
FNAKEVLKQHATHCINEPDLALIKPLI
ECHHHHHHHHHHHCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087; 11342136; 12051918 [H]