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The map label for this gene is 188527421

Identifier: 188527421

GI number: 188527421

Start: 602536

End: 603690

Strand: Direct

Name: 188527421

Synonym: HPSH_03160

Alternate gene names: NA

Gene position: 602536-603690 (Clockwise)

Preceding gene: 188527413

Following gene: 188527422

Centisome position: 37.46

GC content: 41.65

Gene sequence:

>1155_bases
ATGATACCTTTTAAATTCTCTCAAAAATTAAAGGTTAATTTTAACATGTTGCTTTTCACTCCAGGCCCTGTAGCCATTAG
CGAAGAGATGCGCTCAAGCTTTTCTCAGCCAATGCCCCACCACCGCACCAAAGATTTTGAAAAGATTTTCCAAAGCGTGC
GAGAAAATTTAAAAAAAATGACCGGTTTAGAAGAAGTTTTGCTTTTAAATAGTAGCGGGACGGGGGCTATGGAAGCGAGC
GTGGTTTCGTTGTGTCAAAAAGAGTTGCTTTTTGTTAATGCGGGAAAGTTTGGCGAAAGGTTTGGCAAGATCGCTAAAGC
CCATTCTATCAAAGCCCATGAATTAGTCTATGAATGGGACACGCCGGCTCAAGTGGATGGGATATTAAACGCGCTTAAAG
CCAACCCTAACATTGATGCGTTTTGCATTCAAGCATGCGAGTCCAGTGGGGGGTTACGACACCCTGTAGAAAGAATCGCT
CAAGCGATCAAAGAAACTAACCCAAATATTTTTGTGATAGTGGATGCTATCACCGCTTTAGGGGTTGAGCCTTTAGAAAT
AACGCATATTGATGCGCTCATTGGAGGGAGTCAAAAAGCGTTCATGCTGCCTCCTGCGATGAGCCTAATCGCATTGAGCC
AGAAGGCGATTGAACGCATAGAAGAACGCAATGTGGGGTTTTATTTCAATTTAAAGAGCGAATTGAAAAACCAAAGAAAT
AACACCACAAGCTACACCGCTCCTATTTTACACACTTTAGGGTTGCAACGCTATTTTGAATTGGTGCAAAATTTAGGGGG
CTTTGAAGCGCTCTATAAAGAAACTAAAAAAGTCGCTTTAGCCACTCAAAAAGCCGTTTTAGCTTTGGGTTTAAAGATTT
TCCCTAAAAGCCCAAGCTTGAGCATGACAACAATTATTAGCGAGCATGCCAAAGAATTGAGAAACCTTTTAAAAGAAAAA
TACCAGGTGCAATTTGCGGGCGGTCAAGAGCCTTATAAAGACGCGCTCATTCGTATCAACCACATGGGGATCATTCCTGT
TTACAAAAGCGCTTACGCTTTAAACGCCCTAGAATTAGCCCTAAACGACTTGAATTTAAGGGAGTTTGACGGCGTGGCGA
ATACAACCTTTTTGAAGCAATATTATGAAATTTAA

Upstream 100 bases:

>100_bases
TTGCCTTAAATTCTTTTTAAATCATGGCATTTTAGCATTTTATTTGCATTAAAAAGCGATTTTCTTAAACAATAAGGCTT
AATTTTAAGCGCGTTTTAGT

Downstream 100 bases:

>100_bases
GGATTATAATGCATTATTCTTATGAAACCTTTTTAAAAGACAGCCTAGAATTAGTCAAACAAGTAGAGCGAATTTGCGGT
GTCCCAGAAGCCCTTGTGTG

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MIPFKFSQKLKVNFNMLLFTPGPVAISEEMRSSFSQPMPHHRTKDFEKIFQSVRENLKKMTGLEEVLLLNSSGTGAMEAS
VVSLCQKELLFVNAGKFGERFGKIAKAHSIKAHELVYEWDTPAQVDGILNALKANPNIDAFCIQACESSGGLRHPVERIA
QAIKETNPNIFVIVDAITALGVEPLEITHIDALIGGSQKAFMLPPAMSLIALSQKAIERIEERNVGFYFNLKSELKNQRN
NTTSYTAPILHTLGLQRYFELVQNLGGFEALYKETKKVALATQKAVLALGLKIFPKSPSLSMTTIISEHAKELRNLLKEK
YQVQFAGGQEPYKDALIRINHMGIIPVYKSAYALNALELALNDLNLREFDGVANTTFLKQYYEI

Sequences:

>Translated_384_residues
MIPFKFSQKLKVNFNMLLFTPGPVAISEEMRSSFSQPMPHHRTKDFEKIFQSVRENLKKMTGLEEVLLLNSSGTGAMEAS
VVSLCQKELLFVNAGKFGERFGKIAKAHSIKAHELVYEWDTPAQVDGILNALKANPNIDAFCIQACESSGGLRHPVERIA
QAIKETNPNIFVIVDAITALGVEPLEITHIDALIGGSQKAFMLPPAMSLIALSQKAIERIEERNVGFYFNLKSELKNQRN
NTTSYTAPILHTLGLQRYFELVQNLGGFEALYKETKKVALATQKAVLALGLKIFPKSPSLSMTTIISEHAKELRNLLKEK
YQVQFAGGQEPYKDALIRINHMGIIPVYKSAYALNALELALNDLNLREFDGVANTTFLKQYYEI
>Mature_384_residues
MIPFKFSQKLKVNFNMLLFTPGPVAISEEMRSSFSQPMPHHRTKDFEKIFQSVRENLKKMTGLEEVLLLNSSGTGAMEAS
VVSLCQKELLFVNAGKFGERFGKIAKAHSIKAHELVYEWDTPAQVDGILNALKANPNIDAFCIQACESSGGLRHPVERIA
QAIKETNPNIFVIVDAITALGVEPLEITHIDALIGGSQKAFMLPPAMSLIALSQKAIERIEERNVGFYFNLKSELKNQRN
NTTSYTAPILHTLGLQRYFELVQNLGGFEALYKETKKVALATQKAVLALGLKIFPKSPSLSMTTIISEHAKELRNLLKEK
YQVQFAGGQEPYKDALIRINHMGIIPVYKSAYALNALELALNDLNLREFDGVANTTFLKQYYEI

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=348, Percent_Identity=24.1379310344828, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17536281, Length=353, Percent_Identity=24.929178470255, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321079, Length=392, Percent_Identity=23.9795918367347, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17530823, Length=346, Percent_Identity=22.2543352601156, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42879; Mature: 42879

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPFKFSQKLKVNFNMLLFTPGPVAISEEMRSSFSQPMPHHRTKDFEKIFQSVRENLKKM
CCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TGLEEVLLLNSSGTGAMEASVVSLCQKELLFVNAGKFGERFGKIAKAHSIKAHELVYEWD
CCHHHEEEECCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCHHHEEEECC
TPAQVDGILNALKANPNIDAFCIQACESSGGLRHPVERIAQAIKETNPNIFVIVDAITAL
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHC
GVEPLEITHIDALIGGSQKAFMLPPAMSLIALSQKAIERIEERNVGFYFNLKSELKNQRN
CCCCEEEEEEHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCC
NTTSYTAPILHTLGLQRYFELVQNLGGFEALYKETKKVALATQKAVLALGLKIFPKSPSL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
SMTTIISEHAKELRNLLKEKYQVQFAGGQEPYKDALIRINHMGIIPVYKSAYALNALELA
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHEEEECCCEEHHHHHHHHHHHHHHH
LNDLNLREFDGVANTTFLKQYYEI
HHCCCHHHHCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIPFKFSQKLKVNFNMLLFTPGPVAISEEMRSSFSQPMPHHRTKDFEKIFQSVRENLKKM
CCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
TGLEEVLLLNSSGTGAMEASVVSLCQKELLFVNAGKFGERFGKIAKAHSIKAHELVYEWD
CCHHHEEEECCCCCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCHHHEEEECC
TPAQVDGILNALKANPNIDAFCIQACESSGGLRHPVERIAQAIKETNPNIFVIVDAITAL
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHC
GVEPLEITHIDALIGGSQKAFMLPPAMSLIALSQKAIERIEERNVGFYFNLKSELKNQRN
CCCCEEEEEEHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHCCCC
NTTSYTAPILHTLGLQRYFELVQNLGGFEALYKETKKVALATQKAVLALGLKIFPKSPSL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
SMTTIISEHAKELRNLLKEKYQVQFAGGQEPYKDALIRINHMGIIPVYKSAYALNALELA
HHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHEEEECCCEEHHHHHHHHHHHHHHH
LNDLNLREFDGVANTTFLKQYYEI
HHCCCHHHHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]