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The map label for this gene is mrdB [H]

Identifier: 188527413

GI number: 188527413

Start: 595914

End: 597035

Strand: Direct

Name: mrdB [H]

Synonym: HPSH_03120

Alternate gene names: 188527413

Gene position: 595914-597035 (Clockwise)

Preceding gene: 188527396

Following gene: 188527421

Centisome position: 37.05

GC content: 40.64

Gene sequence:

>1122_bases
ATGCATTTTGATTTCTTGCCTTTTGTGTTTATCATCCCCTTGCTTGTGGTTTCTTTTTTATTGATTTTTGAGAGCAGCGC
GGTTTTGAGCTTAAAGCAAGGGGTTTATTATGCGATAGGGTTTCTTCTCTTTTGGATCGTGTTTTTTATCCCTTTCAGGA
AGCTTGATCGGTGGCTCTTTGTGTTTTATTGGGCGTGCGTTATTTTATTAGCGTTAGTGGATTTTATGGGATCGAGCAAG
CTTGGGGCACAGCGATGGCTAGTCATTCCCTTTACCTCTATCACCTTACAGCCTAGCGAACCCGTGAAAATCGCTATCCT
TCTATTATTGGCGCATTTGATTAAAATAAACCCACCCCCTTTTAAGGGCTATGATTGGGGCATGTTTTTAAAGCTTAGTT
TTTACATTTGCTTACCGGCGGCTTTGATTTTAAAACAGCCTGATTTAGGCACGGCTCTTATTGTGTTAATCATGGGTTTT
GGGATTTTATTGATCGTGGGTTTAAGGACTAGGGTGTGGCTCCCTCTTTTTATCGCTCTTTTAGTGGCTTCGCCTATCGC
TTATCACTTTTTGCACGATTATCAAAAAAAGCGCATCGCAGACTTCCTTTCTGAAAAGCCTAGTTACCATGTCATGCAAT
CCATTATCGCTATAGGATCGGGCGGGTTTTTAGGCAAATCTAAAGAAGCCTGCACGCAAACCAAATTCAAATTCTTGCCT
ATCGCAACGAGCGATTTTATCTTCGCTTACTTCGTGGAGCGTTTTGGGTTTTTAGGGGCTATGTTGCTTTTTGCAATTTA
TATAGGCTTGAGTTTGCATTTATTTTTTTACATGTTTGAGAGCAACAGCGATTGGTTTTTAAAGATTGTAGCCCTTGGGA
TTTCTATTTTAATCTTTGTTTATTCCAGCGTGAATATCGCCATGACTTTAGGGTTAACCCCTGTGGTGGGGATTCCCTTG
CCCTTATTTAGCTATGGAGGGAGCAGTTTTATCACTTTTATGATCTTATTTGGGATCTTAGAAAACCTGCTTGCTTTTCG
CTATATTTTTGGATACAATAGCAAACCATCCTTTGGGAATTTTGGATTCTTAGCTCAGCTGGTCAGAGCGCTCGGCTCAT
AA

Upstream 100 bases:

>100_bases
CTTTTTAAGGAGAGTTATCTCAGTTTGGATACTATCAAAAAATTAAAACCATAAGATTAGGGGTTATGAAAAACGCATGG
CATTAGACAAAAGAATCTGG

Downstream 100 bases:

>100_bases
CCGATTGGTCGTAGGTTCAAGTCCTACAGAATCCACCACTCCCCCTTTTTGATCTCTCCCTTTTTAACTGCCCCCTTTTT
AACTGCTCTCTTTTTAAGTG

Product: rod shape-determining protein (mreB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MHFDFLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFLLFWIVFFIPFRKLDRWLFVFYWACVILLALVDFMGSSK
LGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGF
GILLIVGLRTRVWLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPSYHVMQSIIAIGSGGFLGKSKEACTQTKFKFLP
IATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYMFESNSDWFLKIVALGISILIFVYSSVNIAMTLGLTPVVGIPL
PLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS

Sequences:

>Translated_373_residues
MHFDFLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFLLFWIVFFIPFRKLDRWLFVFYWACVILLALVDFMGSSK
LGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGF
GILLIVGLRTRVWLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPSYHVMQSIIAIGSGGFLGKSKEACTQTKFKFLP
IATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYMFESNSDWFLKIVALGISILIFVYSSVNIAMTLGLTPVVGIPL
PLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS
>Mature_373_residues
MHFDFLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFLLFWIVFFIPFRKLDRWLFVFYWACVILLALVDFMGSSK
LGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPPFKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGF
GILLIVGLRTRVWLPLFIALLVASPIAYHFLHDYQKKRIADFLSEKPSYHVMQSIIAIGSGGFLGKSKEACTQTKFKFLP
IATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYMFESNSDWFLKIVALGISILIFVYSSVNIAMTLGLTPVVGIPL
PLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGNFGFLAQLVRALGS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=323, Percent_Identity=39.0092879256966, Blast_Score=169, Evalue=4e-43,
Organism=Escherichia coli, GI1786277, Length=317, Percent_Identity=29.6529968454259, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42147; Mature: 42147

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFDFLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFLLFWIVFFIPFRKLDRWLF
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFYWACVILLALVDFMGSSKLGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPP
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
FKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGFGILLIVGLRTRVWLPLFIAL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVASPIAYHFLHDYQKKRIADFLSEKPSYHVMQSIIAIGSGGFLGKSKEACTQTKFKFLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEE
IATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYMFESNSDWFLKIVALGISILIFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
YSSVNIAMTLGLTPVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGN
HHCCCEEEEECCCCHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FGFLAQLVRALGS
HHHHHHHHHHHCC
>Mature Secondary Structure
MHFDFLPFVFIIPLLVVSFLLIFESSAVLSLKQGVYYAIGFLLFWIVFFIPFRKLDRWLF
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFYWACVILLALVDFMGSSKLGAQRWLVIPFTSITLQPSEPVKIAILLLLAHLIKINPPP
HHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
FKGYDWGMFLKLSFYICLPAALILKQPDLGTALIVLIMGFGILLIVGLRTRVWLPLFIAL
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVASPIAYHFLHDYQKKRIADFLSEKPSYHVMQSIIAIGSGGFLGKSKEACTQTKFKFLP
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEE
IATSDFIFAYFVERFGFLGAMLLFAIYIGLSLHLFFYMFESNSDWFLKIVALGISILIFV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHH
YSSVNIAMTLGLTPVVGIPLPLFSYGGSSFITFMILFGILENLLAFRYIFGYNSKPSFGN
HHCCCEEEEECCCCHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
FGFLAQLVRALGS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]