Click here to switch to the map view.

The map label for this gene is opuCC [H]

Identifier: 188527337

GI number: 188527337

Start: 524952

End: 526613

Strand: Reverse

Name: opuCC [H]

Synonym: HPSH_02720

Alternate gene names: 188527337

Gene position: 526613-524952 (Counterclockwise)

Preceding gene: 188527338

Following gene: 188527336

Centisome position: 32.74

GC content: 40.07

Gene sequence:

>1662_bases
ATGCCAAGCATGGGCGTTTTTAAACATTTATTCAAAGAATTGCATGAATGGTTGCTCCATTCTGTAGATGTAATCACACA
GCATTTAGTTGCCATAGTGCTAAAAATAAGCGTGGTAAAACATTTGATACAAGAATTTCATGATCGCTTCATTTATTTTG
TAGATTTACTCGCGCAGCATTTTATCATCGTTGCACTTTCTAGCTTTCTTGTGCTGGTGTTTGGGGTTTTGATTGGGGTT
TTTGTGTTTTACAACTCAAAGGCTAGGGCGTTCTTGCTCCCTATAGTGAATTTCCTCTACACCATCCCATCGCTTGCGTT
ATTCGCGTTATTCATTCCTTTAATTGGGGTGGGGTTAAAAAATGCGCTTTTAGTGTTGGTCTTATACGGCTTATTACCCA
TTGTCCATAGCACTTATAACGCTTTAAAAGAGGTGAGAGAAGAGGTGATTAAGGCCGCTATCGGACTAGGGTGTAACCCA
AAAGAGTTGTTTTTTAGGGTGCGATTCTTGCTCGCTATCCCCCAAATTTTAGTGGGCTTAAGGATTGCGGTGGTGATGCT
AGTAGCGATGGCTGGGATTGGGGCGCTCATTGGGGCTGGGGGATTAGGGCAGGCGATTTTTAGAGGGCTAAACACGCAAA
ACACCACGCTTTTAGTGGCGGGCAGTTTGATCATTGCTCTTTTTAGTGTTTTAGCGGATCAATTTGTGAGCGTCTTTCAG
CATGAAAACGCCTTGCAACGCCTATTTTCTCAAAACGCCACCAAAAAACAAAAAAGAAAAGTTTATCTCAATTTAGCGGT
GTTCCTTTTTTTATTGCTAGCGAGCGCTTTATGGCTCATTCCTAGAAACGCCATAGAAGAAAAGCCCTTAGTCGTGGCGG
CAAAACCCAGCAGCGAGCAGTATATTTTGGGCGAGATTTTAAGCCTTTTGTTAGAAAAACACCATATCCCTATCAAGCGA
GCGTTTGGCATTGGTGGGGGGACGATGAATATCCATCCGGCATTAATTAGGGGCGATTTTGATTTGTATGTGGAATATAC
CGGCACCGCTTGGGTGAATACGCTCAAAAACCCTTTGACTCAAAAAGTGGATTTTGAAACGATTAAAAAGCGTTATGAGA
AGGAATTCAATCTTTTATGGGTGGGGCTTTTGGGCTTTAATAACACCTATTCCTTAGCGATTTCTAAAGAAGACGCTCAA
AAATACGCTATAGAAACTTTCAGCGATTTAGCCTTTCATAGCCCAAATTTTGATTTTGGAGCGGAGTTTGACTTTTTTGA
AAGAGAGGACGCTTTTAAAGGCTTAGTGAAAGCCTATCCATTCCATTTTAGAAGTTTGCATGAAATGGATATTAATTTGC
GCTATAAAAGTTTTGAATCCCATAAAATCAACGCTTTAGATGTCTTCACTACAGACGCTCAAATCAAAGAGTTGGATTTA
AGAGTGCTTAAGGATGATAAAGGGTTTTTCCCCAATTATCAGGCCGGTATTGTTATGAGAAAAGAAATTGTAAAAAAGTA
TCCGGAAGCGTTAAAAATCTTAGAAAAATTGGATTCAAAATTTAGCGATGAGGTGATGCAAGATTTAAACTATCAGGTGG
AAGTGTTGAAAAAAAGCCCCCAAATAGTCGCTAAAGATTTTTTAGAGAGATTGGGGTTATAG

Upstream 100 bases:

>100_bases
AGGTAACATGAAAGAGTATTATAACAAAGCCCACTCATTAAACGCTTACCCCCATGCAAAAACTAAATAAAACCCCTTTA
TTCAAATAAGTTTAGTTATA

Downstream 100 bases:

>100_bases
TATGAAAGAAGTCGTTACAATAGAGAATGTGTCTTTTAACTACCACAATCGCACTATTTTTAAGGGTTTTAATTTAAGCA
TTCAAGAAGGGGATTTTTTA

Product: osmoprotection protein (proWX)

Products: NA

Alternate protein names: Osmoprotectant-binding protein [H]

Number of amino acids: Translated: 553; Mature: 552

Protein sequence:

>553_residues
MPSMGVFKHLFKELHEWLLHSVDVITQHLVAIVLKISVVKHLIQEFHDRFIYFVDLLAQHFIIVALSSFLVLVFGVLIGV
FVFYNSKARAFLLPIVNFLYTIPSLALFALFIPLIGVGLKNALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNP
KELFFRVRFLLAIPQILVGLRIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSLIIALFSVLADQFVSVFQ
HENALQRLFSQNATKKQKRKVYLNLAVFLFLLLASALWLIPRNAIEEKPLVVAAKPSSEQYILGEILSLLLEKHHIPIKR
AFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLTQKVDFETIKKRYEKEFNLLWVGLLGFNNTYSLAISKEDAQ
KYAIETFSDLAFHSPNFDFGAEFDFFEREDAFKGLVKAYPFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
RVLKDDKGFFPNYQAGIVMRKEIVKKYPEALKILEKLDSKFSDEVMQDLNYQVEVLKKSPQIVAKDFLERLGL

Sequences:

>Translated_553_residues
MPSMGVFKHLFKELHEWLLHSVDVITQHLVAIVLKISVVKHLIQEFHDRFIYFVDLLAQHFIIVALSSFLVLVFGVLIGV
FVFYNSKARAFLLPIVNFLYTIPSLALFALFIPLIGVGLKNALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNP
KELFFRVRFLLAIPQILVGLRIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSLIIALFSVLADQFVSVFQ
HENALQRLFSQNATKKQKRKVYLNLAVFLFLLLASALWLIPRNAIEEKPLVVAAKPSSEQYILGEILSLLLEKHHIPIKR
AFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLTQKVDFETIKKRYEKEFNLLWVGLLGFNNTYSLAISKEDAQ
KYAIETFSDLAFHSPNFDFGAEFDFFEREDAFKGLVKAYPFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
RVLKDDKGFFPNYQAGIVMRKEIVKKYPEALKILEKLDSKFSDEVMQDLNYQVEVLKKSPQIVAKDFLERLGL
>Mature_552_residues
PSMGVFKHLFKELHEWLLHSVDVITQHLVAIVLKISVVKHLIQEFHDRFIYFVDLLAQHFIIVALSSFLVLVFGVLIGVF
VFYNSKARAFLLPIVNFLYTIPSLALFALFIPLIGVGLKNALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNPK
ELFFRVRFLLAIPQILVGLRIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSLIIALFSVLADQFVSVFQH
ENALQRLFSQNATKKQKRKVYLNLAVFLFLLLASALWLIPRNAIEEKPLVVAAKPSSEQYILGEILSLLLEKHHIPIKRA
FGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLTQKVDFETIKKRYEKEFNLLWVGLLGFNNTYSLAISKEDAQK
YAIETFSDLAFHSPNFDFGAEFDFFEREDAFKGLVKAYPFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDLR
VLKDDKGFFPNYQAGIVMRKEIVKKYPEALKILEKLDSKFSDEVMQDLNYQVEVLKKSPQIVAKDFLERLGL

Specific function: Member of a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine, and choline [H]

COG id: COG1732

COG function: function code M; Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788452, Length=285, Percent_Identity=26.6666666666667, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788451, Length=209, Percent_Identity=33.4928229665072, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788449, Length=185, Percent_Identity=32.4324324324324, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1789033, Length=200, Percent_Identity=23, Blast_Score=85, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 62626; Mature: 62495

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSMGVFKHLFKELHEWLLHSVDVITQHLVAIVLKISVVKHLIQEFHDRFIYFVDLLAQH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIIVALSSFLVLVFGVLIGVFVFYNSKARAFLLPIVNFLYTIPSLALFALFIPLIGVGLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNPKELFFRVRFLLAIPQILVGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSLIIALFSVLADQFVSVFQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
HENALQRLFSQNATKKQKRKVYLNLAVFLFLLLASALWLIPRNAIEEKPLVVAAKPSSEQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEECCCCCC
YILGEILSLLLEKHHIPIKRAFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLT
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCEECHHEEECCEEEEEEECCHHHHHHHHHHHH
QKVDFETIKKRYEKEFNLLWVGLLGFNNTYSLAISKEDAQKYAIETFSDLAFHSPNFDFG
HCCCHHHHHHHHHHHHCEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCC
AEFDFFEREDAFKGLVKAYPFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCHHHHHHH
RVLKDDKGFFPNYQAGIVMRKEIVKKYPEALKILEKLDSKFSDEVMQDLNYQVEVLKKSP
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCH
QIVAKDFLERLGL
HHHHHHHHHHHCC
>Mature Secondary Structure 
PSMGVFKHLFKELHEWLLHSVDVITQHLVAIVLKISVVKHLIQEFHDRFIYFVDLLAQH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FIIVALSSFLVLVFGVLIGVFVFYNSKARAFLLPIVNFLYTIPSLALFALFIPLIGVGLK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NALLVLVLYGLLPIVHSTYNALKEVREEVIKAAIGLGCNPKELFFRVRFLLAIPQILVGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
RIAVVMLVAMAGIGALIGAGGLGQAIFRGLNTQNTTLLVAGSLIIALFSVLADQFVSVFQ
HHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
HENALQRLFSQNATKKQKRKVYLNLAVFLFLLLASALWLIPRNAIEEKPLVVAAKPSSEQ
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCEEEEECCCCCC
YILGEILSLLLEKHHIPIKRAFGIGGGTMNIHPALIRGDFDLYVEYTGTAWVNTLKNPLT
HHHHHHHHHHHHHCCCCHHHHCCCCCCCCEECHHEEECCEEEEEEECCHHHHHHHHHHHH
QKVDFETIKKRYEKEFNLLWVGLLGFNNTYSLAISKEDAQKYAIETFSDLAFHSPNFDFG
HCCCHHHHHHHHHHHHCEEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCC
AEFDFFEREDAFKGLVKAYPFHFRSLHEMDINLRYKSFESHKINALDVFTTDAQIKELDL
CCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEECCCCCCCCEEEEEECCCHHHHHHH
RVLKDDKGFFPNYQAGIVMRKEIVKKYPEALKILEKLDSKFSDEVMQDLNYQVEVLKKSP
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCH
QIVAKDFLERLGL
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]