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The map label for this gene is gmhB [H]

Identifier: 188527295

GI number: 188527295

Start: 483931

End: 484455

Strand: Direct

Name: gmhB [H]

Synonym: HPSH_02510

Alternate gene names: 188527295

Gene position: 483931-484455 (Clockwise)

Preceding gene: 188527294

Following gene: 188527296

Centisome position: 30.08

GC content: 36.57

Gene sequence:

>525_bases
ATGAGCGCCACTAACAAAGCCCTTTTTTTGGACAGAGACGGCATTATCAATATTGATAAAGGCTATGTGAGTCAAAAAGA
AGATTTTGAGTTCCAAAAAGGGATTTTTGAATTACTAAACCATGCGAAATCTTTAGGCTACAAACTGCTTTTAATCACCA
ACCAATCTGGGATCAACCGGGGTTATTACACCCTTAAAGATTTTGAAACACTCACCGAATACCTTCAAGAAAGCTTGCTT
AAAGAATTAGGTTTTAATTTGGATGGCATCTATTTTTGCAGGCACGCCCCAGAAGAAAATTGCGCTTGCAGAAAGCCAAA
GCCCTCTTTGATTTTGCAAGCCGCTAAAGAGCATCAAATTTGCTTGGAGCAATCTTTTATGATAGGCGATAAAGAGAGCG
ACATGTTAGCCGGCTTGAACGCTAAAGTTAAAAACAACCTTTTATTGACCACAAATGTTTTAAAAACTCCTCATTCTTGG
ATACAATGTAAAGATTTTAAAGAGATAATAGATCTAATCAAATAA

Upstream 100 bases:

>100_bases
CTTTATATTCTTTATATGGGGATCATGCTCATTAACCACCAAAACCCCCATGCGATGCATCATTCAAGCGAAACCACCCA
ACACGATCACAAGGGAATGC

Downstream 100 bases:

>100_bases
GGACAAGAATGCGTTATATTGATGATGAGTTAGAAAATCAAACGATTTTAATCACCGGTGGGGCTGGCTTTGTAGGCAGT
AATTTGGCCTTTTATTTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MSATNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLNHAKSLGYKLLLITNQSGINRGYYTLKDFETLTEYLQESLL
KELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLTTNVLKTPHSW
IQCKDFKEIIDLIK

Sequences:

>Translated_174_residues
MSATNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLNHAKSLGYKLLLITNQSGINRGYYTLKDFETLTEYLQESLL
KELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLTTNVLKTPHSW
IQCKDFKEIIDLIK
>Mature_173_residues
SATNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLNHAKSLGYKLLLITNQSGINRGYYTLKDFETLTEYLQESLLK
ELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQICLEQSFMIGDKESDMLAGLNAKVKNNLLLTTNVLKTPHSWI
QCKDFKEIIDLIK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=166, Percent_Identity=41.566265060241, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082027, Length=135, Percent_Identity=31.1111111111111, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: 3.1.1.-

Molecular weight: Translated: 19909; Mature: 19778

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLNHAKSLGYKLLLITNQSGINR
CCCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
GYYTLKDFETLTEYLQESLLKELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQI
CCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
CLEQSFMIGDKESDMLAGLNAKVKNNLLLTTNVLKTPHSWIQCKDFKEIIDLIK
HHHHHHHCCCCCCHHHHCCCCHHHCCEEEEEHHHHCCCHHEEHHHHHHHHHHHC
>Mature Secondary Structure 
SATNKALFLDRDGIINIDKGYVSQKEDFEFQKGIFELLNHAKSLGYKLLLITNQSGINR
CCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCCCCC
GYYTLKDFETLTEYLQESLLKELGFNLDGIYFCRHAPEENCACRKPKPSLILQAAKEHQI
CCEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
CLEQSFMIGDKESDMLAGLNAKVKNNLLLTTNVLKTPHSWIQCKDFKEIIDLIK
HHHHHHHCCCCCCHHHHCCCCHHHCCEEEEEHHHHCCCHHEEHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 12101286 [H]