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The map label for this gene is prmA

Identifier: 188527189

GI number: 188527189

Start: 379127

End: 380116

Strand: Reverse

Name: prmA

Synonym: HPSH_01980

Alternate gene names: 188527189

Gene position: 380116-379127 (Counterclockwise)

Preceding gene: 188527190

Following gene: 188527188

Centisome position: 23.63

GC content: 37.68

Gene sequence:

>990_bases
GTGTTAAAGCCAATGTATTATGAATTTTTCTTTATCTTCCCTAAGGAGCAAGAGCTTTTTGAGAGCTTTCTTTTAGACAC
CACGCATCTAGCCCTAGAAGAATCAAGCCTAGAAAGTTTAAAAGCGTTTGACGATAAAGAAACCATTGAATTTATAAGCC
AATCCAGTTGGCATTATTTCGCCACTCATGACCCTTTAAAAGAAAATTTAAAAGAAAAACCCCCACACCTCAAAAATTTC
GTTATTTTACGCTCTCAAAAGGATTTGAACGACTCACTCATTCCAGCATTAAAAGCGTTTTGCTTGAGCTTGCAACAAAA
CCTGCAAAGCGGGTTTGATTTTTTCTATCTTTCACGCAATTTGGCTTCAAAAGATTGGCTAGAAGCCTACAAACAAGCTA
TTTTGCCGGTGCAATGCGCCAAATTTTACATACACCCTAGCTGGCATCAAAAACCAAGCCATGTCGCTACAGATGATAGC
ATAATGATTGATCCGGCTCTTGCCTTTGGATCAGGCCATCATGAAAGCACTTCTATATGTTTGGAACTGCTCTCTAACCT
TGATTTAAAACGCAAAAACGCTTTAGATGTGGGCTGTGGGAGCGGGATTTTAAGCATCGCTTTAAAAAAACAAGGCGTTA
GCGCTTTAAGCGCTTGCGATACGGATAGTTTAGCCGTTGAAGAAACCCTAAAAAATTTTAGTTTGAATCAAATCACCCTA
TTAGCGCAAGATAAAGTCATTCATGGCTCTACGCAAAAAATTGAAGGGCGTTTTGATATTATTGTAGCGAACATTGTCGC
TGATGTGATTAAGAGTTTGTATAGTGAATTTGTGCGGCTTTGTAACCACACTCTTATTTTATCAGGGATTTTAGAAACCC
ATTTAAACTCTGTTTTACAGATCTATTATAATGGATTTGAGGTTTTAGAGCAACGACAGCGTAACGAATGGGTCGCTCTA
AAATTGCTTAAAAAACAATCAATAAATTAA

Upstream 100 bases:

>100_bases
TACGGCTTTGAAAGCGGGCGTGAATAACTACATTGTGAAGCCTTTTACCCCCCAGGTTTTGAAAGAAAAATTAGAGGTTG
TTTTAGGGACAAACGATTGA

Downstream 100 bases:

>100_bases
GGATTATAATGAAACCAACGAACGAACCTAAAAAACCTTTTTTTCAAAGTCCCATTATCCTTGCGGTTCTTGGAGGGATT
TTACTCATCTTTTTCCTACG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MLKPMYYEFFFIFPKEQELFESFLLDTTHLALEESSLESLKAFDDKETIEFISQSSWHYFATHDPLKENLKEKPPHLKNF
VILRSQKDLNDSLIPALKAFCLSLQQNLQSGFDFFYLSRNLASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHVATDDS
IMIDPALAFGSGHHESTSICLELLSNLDLKRKNALDVGCGSGILSIALKKQGVSALSACDTDSLAVEETLKNFSLNQITL
LAQDKVIHGSTQKIEGRFDIIVANIVADVIKSLYSEFVRLCNHTLILSGILETHLNSVLQIYYNGFEVLEQRQRNEWVAL
KLLKKQSIN

Sequences:

>Translated_329_residues
MLKPMYYEFFFIFPKEQELFESFLLDTTHLALEESSLESLKAFDDKETIEFISQSSWHYFATHDPLKENLKEKPPHLKNF
VILRSQKDLNDSLIPALKAFCLSLQQNLQSGFDFFYLSRNLASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHVATDDS
IMIDPALAFGSGHHESTSICLELLSNLDLKRKNALDVGCGSGILSIALKKQGVSALSACDTDSLAVEETLKNFSLNQITL
LAQDKVIHGSTQKIEGRFDIIVANIVADVIKSLYSEFVRLCNHTLILSGILETHLNSVLQIYYNGFEVLEQRQRNEWVAL
KLLKKQSIN
>Mature_329_residues
MLKPMYYEFFFIFPKEQELFESFLLDTTHLALEESSLESLKAFDDKETIEFISQSSWHYFATHDPLKENLKEKPPHLKNF
VILRSQKDLNDSLIPALKAFCLSLQQNLQSGFDFFYLSRNLASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHVATDDS
IMIDPALAFGSGHHESTSICLELLSNLDLKRKNALDVGCGSGILSIALKKQGVSALSACDTDSLAVEETLKNFSLNQITL
LAQDKVIHGSTQKIEGRFDIIVANIVADVIKSLYSEFVRLCNHTLILSGILETHLNSVLQIYYNGFEVLEQRQRNEWVAL
KLLKKQSIN

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=215, Percent_Identity=33.0232558139535, Blast_Score=97, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 37446; Mature: 37446

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKPMYYEFFFIFPKEQELFESFLLDTTHLALEESSLESLKAFDDKETIEFISQSSWHYF
CCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
ATHDPLKENLKEKPPHLKNFVILRSQKDLNDSLIPALKAFCLSLQQNLQSGFDFFYLSRN
ECCCHHHHHHHHCCCCHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHC
LASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHVATDDSIMIDPALAFGSGHHESTSIC
CCCHHHHHHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCCEEECCHHHCCCCCCHHHHHH
LELLSNLDLKRKNALDVGCGSGILSIALKKQGVSALSACDTDSLAVEETLKNFSLNQITL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCEEEE
LAQDKVIHGSTQKIEGRFDIIVANIVADVIKSLYSEFVRLCNHTLILSGILETHLNSVLQ
EECCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYYNGFEVLEQRQRNEWVALKLLKKQSIN
HHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLKPMYYEFFFIFPKEQELFESFLLDTTHLALEESSLESLKAFDDKETIEFISQSSWHYF
CCCCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
ATHDPLKENLKEKPPHLKNFVILRSQKDLNDSLIPALKAFCLSLQQNLQSGFDFFYLSRN
ECCCHHHHHHHHCCCCHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEHHC
LASKDWLEAYKQAILPVQCAKFYIHPSWHQKPSHVATDDSIMIDPALAFGSGHHESTSIC
CCCHHHHHHHHHHHCHHHHHHEEECCCCCCCCCCCCCCCCEEECCHHHCCCCCCHHHHHH
LELLSNLDLKRKNALDVGCGSGILSIALKKQGVSALSACDTDSLAVEETLKNFSLNQITL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCEEEE
LAQDKVIHGSTQKIEGRFDIIVANIVADVIKSLYSEFVRLCNHTLILSGILETHLNSVLQ
EECCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYYNGFEVLEQRQRNEWVALKLLKKQSIN
HHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9244252; 9252185 [H]