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The map label for this gene is argS

Identifier: 188527123

GI number: 188527123

Start: 318162

End: 319787

Strand: Reverse

Name: argS

Synonym: HPSH_01650

Alternate gene names: 188527123

Gene position: 319787-318162 (Counterclockwise)

Preceding gene: 188527124

Following gene: 188527122

Centisome position: 19.88

GC content: 38.25

Gene sequence:

>1626_bases
ATGCACACTCTCATTAAGGGCGTTTTAGAAGAGATTTTAGAAGAAGAAGTCATTATTGAATACCCTAAAGACAGAGAGCA
TGGGCATTACGCTACGCCCATTGCTTTCAATCTCGCCAAAGTTTTTAAAAAATCGCCCTTAGTTATCGCTGAAGAATTAG
CCCTTAAGATCAGCACGCATGAAAAAACTCAAGGGCTTTTTGACAGCGTAGTGGCTTGTAAGGGCTATATCAATTTCACG
CTTTCTTTAGATTTTTTAGAGCGTTTCACCCAAAAGGCTTTAGAATTAAAAGAAAAATTCGGCTCTCAGCCTAAAAGCGA
GCGTTCTCAAAAAATCTTTTTAGAATTTGTGAGCGCTAACCCCACAGGGCCTTTACACATAGGGCATGCTAGAGGGGCGG
TGTTTGGCGATAGTTTGGCTAAAATCGCTCGCTTTTTAGGGCATGAAGTTTTGTGCGAATATTATGTTAATGACATGGGA
TCTCAAATCCGCTTGTTAGGGCTTTCTGTATGGCTCGCTTACAGAGAGCATGTTTTAAAAGAAAGCGTAACTTACCCAGA
AGTCTTTTACAAAGGCGAATACATCATTGAGATCGCTAAAAAGGCGAACAACGATTTAGAGCCAAGCCTTTTTAAAGAAA
ACGAAGAAACTATTATTGAAGTTTTAAGCGGCTATGCTAAAGATTTAATGCTTTTAGAAATTAAAGATAATTTAGACGCT
TTAGGCATTCATTTTGATTCTTATGCGAGCGAAAGAGAAGTTTTTAAACATAAAGATGCGGTGTTTGAACGATTAGAAAA
AGCGAACGCCCTTTATGAAAAGGATTCTAAAATCTGGCTCAAATCTTCACTCTACCAGGATGAAAGCGATCGGGTGCTCA
TTAAAGAAGACAAGAGCTACACTTATTTAGCGGGCGATATTGTCTATCATGATGAAAAATTCAAGCAAAACTACACCAAA
TATATCAACATTTGGGGGGCAGACCACCACGGCTATATCGCTAGAGTGAAAGCCAGCCTTGAGTTTTTGGGCTATGATTC
CAATAAGCTTGAAGTCTTGCTCGCTCAAATGGTGCGCTTGCTCAAAGATAACGAGCCTTACAAAATGAGTAAAAGAGCGG
GTAATTTCATTTTGATTAAAGATGTGATTGATGATGTGGGTAAAGACGCTTTAAGGTTTATTTTTTTAAGCAAACGGCTT
GACACGCATTTAGAATTTGATGTCAATACTTTAAAAAAGCAAGACAGCTCAAACCCTATTTACTATATCCATTACGCTAA
TTCGCGCATCCACACCATGCTAGAAAAATCGCCCTTTTCTAAAGAAGAGGTTTTACAAACCCCTTTAACCGATTTGAACG
CTGAAGAAAAATACCTGCTTTTTAGCGCTTTAAGCTTGCCTAAAATCATTGAATCTTCTTTTGAAGAATACGGCTTGCAA
AAAATGTGCGAATACGCAAAAACCCTCGCCTCAGAATTCCACCGCTTCTATAACGCTGGCAAAATTTTAGACACCCCTAA
AGCTAAAGAGCTTTTAAAAATTTGTTTGATGGTGAGTTTGAGTTTGAGCAACGCTTTCAAACTTTTAGGCATAGAGATAA
AAACCAAAATTTCCGCTAAAGATTAA

Upstream 100 bases:

>100_bases
AAGAAGAGGCTAAAAACGAGCCAAAAACCCTAGACGCTCAAGTAGCACAAACCAAAGTGCATGAAACTAGCGAGATTAAA
AGCAAACAAGAAAGTTAAAC

Downstream 100 bases:

>100_bases
GCTAATATTTAATTTTTTGTTATAACATTCCCCTTATTTTTTGAAATTAAGGAGAATATTTTGCTTAATCGTATTATAGA
ACACATGAACGCTCACCATG

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSVVACKGYINFT
LSLDFLERFTQKALELKEKFGSQPKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
LGIHFDSYASEREVFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQNYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTDLNAEEKYLLFSALSLPKIIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLSNAFKLLGIEIKTKISAKD

Sequences:

>Translated_541_residues
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSVVACKGYINFT
LSLDFLERFTQKALELKEKFGSQPKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
LGIHFDSYASEREVFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQNYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTDLNAEEKYLLFSALSLPKIIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLSNAFKLLGIEIKTKISAKD
>Mature_541_residues
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTHEKTQGLFDSVVACKGYINFT
LSLDFLERFTQKALELKEKFGSQPKSERSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMG
SQIRLLGLSVWLAYREHVLKESVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
LGIHFDSYASEREVFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSYTYLAGDIVYHDEKFKQNYTK
YINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRLLKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRL
DTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEVLQTPLTDLNAEEKYLLFSALSLPKIIESSFEEYGLQ
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLSNAFKLLGIEIKTKISAKD

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=600, Percent_Identity=22, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI197100773, Length=327, Percent_Identity=24.7706422018349, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1788184, Length=559, Percent_Identity=22.3613595706619, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321883, Length=555, Percent_Identity=21.981981981982, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28571570, Length=319, Percent_Identity=27.8996865203762, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 62212; Mature: 62212

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTH
CHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHEEECC
EKTQGLFDSVVACKGYINFTLSLDFLERFTQKALELKEKFGSQPKSERSQKIFLEFVSAN
HHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEECCC
PTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ESVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
HCCCCCHHHCCCHHEEEEHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCE
LGIHFDSYASEREVFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSY
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCEEEEEECCCE
TYLAGDIVYHDEKFKQNYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRL
EEEEEEEEECCHHHHCCCEEEEEEECCCCCCCCEEEEEHHHEECCCCCHHHHHHHHHHHH
LKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPI
HCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCE
YYIHYANSRIHTMLEKSPFSKEEVLQTPLTDLNAEEKYLLFSALSLPKIIESSFEEYGLQ
EEEEECCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLSNAFKLLGIEIKTKISAK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCC
D
C
>Mature Secondary Structure
MHTLIKGVLEEILEEEVIIEYPKDREHGHYATPIAFNLAKVFKKSPLVIAEELALKISTH
CHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHHHHEEECC
EKTQGLFDSVVACKGYINFTLSLDFLERFTQKALELKEKFGSQPKSERSQKIFLEFVSAN
HHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHEEEEEEECCC
PTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLK
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ESVTYPEVFYKGEYIIEIAKKANNDLEPSLFKENEETIIEVLSGYAKDLMLLEIKDNLDA
HCCCCCHHHCCCHHEEEEHHHCCCCCCCHHHCCCHHHHHHHHHHHHHCEEEEEECCCCCE
LGIHFDSYASEREVFKHKDAVFERLEKANALYEKDSKIWLKSSLYQDESDRVLIKEDKSY
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCCCEEEEEECCCE
TYLAGDIVYHDEKFKQNYTKYINIWGADHHGYIARVKASLEFLGYDSNKLEVLLAQMVRL
EEEEEEEEECCHHHHCCCEEEEEEECCCCCCCCEEEEEHHHEECCCCCHHHHHHHHHHHH
LKDNEPYKMSKRAGNFILIKDVIDDVGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPI
HCCCCCCCHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHCCCCCCCE
YYIHYANSRIHTMLEKSPFSKEEVLQTPLTDLNAEEKYLLFSALSLPKIIESSFEEYGLQ
EEEEECCCHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KMCEYAKTLASEFHRFYNAGKILDTPKAKELLKICLMVSLSLSNAFKLLGIEIKTKISAK
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA