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The map label for this gene is hcpA [H]

Identifier: 188527015

GI number: 188527015

Start: 203212

End: 203964

Strand: Reverse

Name: hcpA [H]

Synonym: HPSH_01090

Alternate gene names: 188527015

Gene position: 203964-203212 (Counterclockwise)

Preceding gene: 188527016

Following gene: 188527012

Centisome position: 12.68

GC content: 39.97

Gene sequence:

>753_bases
ATGCTAGGAAGCGTTAAAAAAACCCTTTTTGGGGTCTTGTGTTTGGGCGCGTTGTGTTTGAGAGGGTTAATGGCAGAGCC
AGACGCTAAAGAGCTTGTTAATTTAGGTATAGAGAGCGCAAAGAAGCAAGATTTCACTCAAGCTAAAACGCATTTTGAAA
AAGCTTGTGAGTTAAAAGATGGCTTTGGGTGTGTTTTTTTAGGGGCGTTCTATGAAGAAGGGAAAGGAGTGGGAAAAGAC
TTGAAAAAAGCCGTTCAATTTTACACTAAAGGTTGTGAATTGAATGATGGTTATGGGTGCCGTCTGTTAGGCAATTTATA
CTATAACGGACAAGGCGTGCCTAAAGACGCCAAAAAAGCCTCACAATATTACTCTAAATCTTGCGAATTAAACCATGCTG
AAGGGTGTATGGTATTAGGAAGCTTGCATCATCATGGCGTAGGCACGCCTAAGGATTCAAGAAAGGCTCTTGATTTGTAT
GAAAAAGCTTGCGATTTAAAAGATAGCCCAGGGTGTATTAACGCAGGATACATATATGGTACAGCAAAGAATTTTAAGGA
GGCTGTCGTTCGTTATTCTCAAGCTTGCGAGTTGAATGATGGTAGGGGGTGTTATAATTTAGGGGTTATGCAATATAATG
GAAAAGGCACAGCAAAGGACGAAAAGCAAGCGGTAGAAAACTTTAAAAAAGGTTGCAAATCAGGCGTTAAAGAAGCATGT
GATGCTCTCAAGGAATTAAAAATAGAACTTTAG

Upstream 100 bases:

>100_bases
TTAAGCGAGAAGTAGAACCAAGGGGCATTCAATAAGGCTTTAATCGTCAATATTTGATTATAATTATAAAGGATTACATT
TCTTTAATAGGAGATATATC

Downstream 100 bases:

>100_bases
TTTCAAAACCACCCAAGCAGAAATCCTAAACATCTTTAGTGTTTGGGATGAATGTTGCTAATTTGTAGTATAATGCCCCC
ATGCATTTGTATCTAGCACA

Product: cysteine-rich protein A

Products: NA

Alternate protein names: Cysteine-rich 28 kDa protein [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFTQAKTHFEKACELKDGFGCVFLGAFYEEGKGVGKD
LKKAVQFYTKGCELNDGYGCRLLGNLYYNGQGVPKDAKKASQYYSKSCELNHAEGCMVLGSLHHHGVGTPKDSRKALDLY
EKACDLKDSPGCINAGYIYGTAKNFKEAVVRYSQACELNDGRGCYNLGVMQYNGKGTAKDEKQAVENFKKGCKSGVKEAC
DALKELKIEL

Sequences:

>Translated_250_residues
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFTQAKTHFEKACELKDGFGCVFLGAFYEEGKGVGKD
LKKAVQFYTKGCELNDGYGCRLLGNLYYNGQGVPKDAKKASQYYSKSCELNHAEGCMVLGSLHHHGVGTPKDSRKALDLY
EKACDLKDSPGCINAGYIYGTAKNFKEAVVRYSQACELNDGRGCYNLGVMQYNGKGTAKDEKQAVENFKKGCKSGVKEAC
DALKELKIEL
>Mature_250_residues
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFTQAKTHFEKACELKDGFGCVFLGAFYEEGKGVGKD
LKKAVQFYTKGCELNDGYGCRLLGNLYYNGQGVPKDAKKASQYYSKSCELNHAEGCMVLGSLHHHGVGTPKDSRKALDLY
EKACDLKDSPGCINAGYIYGTAKNFKEAVVRYSQACELNDGRGCYNLGVMQYNGKGTAKDEKQAVENFKKGCKSGVKEAC
DALKELKIEL

Specific function: Slowly hydrolyzes 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives. May be involved in the synthesis of the cell wall peptidoglycan [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 5 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI87081769, Length=241, Percent_Identity=24.0663900414938, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17563256, Length=203, Percent_Identity=25.615763546798, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355295, Length=171, Percent_Identity=30.9941520467836, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007256, Length=218, Percent_Identity=29.8165137614679, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 27226; Mature: 27226

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
5.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFTQAKTHFEKACELKD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFGCVFLGAFYEEGKGVGKDLKKAVQFYTKGCELNDGYGCRLLGNLYYNGQGVPKDAKKA
CCCCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECEEECCCCCCHHHHHH
SQYYSKSCELNHAEGCMVLGSLHHHGVGTPKDSRKALDLYEKACDLKDSPGCINAGYIYG
HHHHHHCCCCCCCCCHHEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCEEEE
TAKNFKEAVVRYSQACELNDGRGCYNLGVMQYNGKGTAKDEKQAVENFKKGCKSGVKEAC
CHHHHHHHHHHHHHHCCCCCCCCEEEECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
DALKELKIEL
HHHHHHHCCC
>Mature Secondary Structure
MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVNLGIESAKKQDFTQAKTHFEKACELKD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GFGCVFLGAFYEEGKGVGKDLKKAVQFYTKGCELNDGYGCRLLGNLYYNGQGVPKDAKKA
CCCCEEHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECEEECCCCCCHHHHHH
SQYYSKSCELNHAEGCMVLGSLHHHGVGTPKDSRKALDLYEKACDLKDSPGCINAGYIYG
HHHHHHCCCCCCCCCHHEEHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCEECCEEEE
TAKNFKEAVVRYSQACELNDGRGCYNLGVMQYNGKGTAKDEKQAVENFKKGCKSGVKEAC
CHHHHHHHHHHHHHHCCCCCCCCEEEECEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
DALKELKIEL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]