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The map label for this gene is mcp4 [H]

Identifier: 188526904

GI number: 188526904

Start: 91315

End: 93351

Strand: Direct

Name: mcp4 [H]

Synonym: HPSH_00495

Alternate gene names: 188526904

Gene position: 91315-93351 (Clockwise)

Preceding gene: 188526901

Following gene: 188526905

Centisome position: 5.68

GC content: 39.37

Gene sequence:

>2037_bases
TTGTCTAAAGGTTTGAGTATCGGTAATAAAATCATATTGTGCGTGGCGTTGATTGTGATCGTGTGCGTGAGCATTTTAGG
GGTGTCCTTAAACAGCAGGGTGAAAGAGATTTTAAAAGAAAATGCCCTGCATTCTATGCAAGATAGTTTGCATTTCAAGG
TTAAGGAAGTGCAAGGGATTCTTGAAAACACTTATACGAGCATGGGCATTGTCAAAGAAATGCTCCCTAAAGACACCAAA
AGAGAAATCAAAATCCACTTGTTAAAAAACTTCATTTTAGCCAATTCGCATGTCGTTGGGGCGAGCATGTTTTTTAAAGA
CAGAGAAGATTTAAGATTCACGCTTTTAAGGGATAACGATACGATTAAGCTAGTGGAAAATCCGTCATTGGGGAATAACC
CTTTAGTGCAAAAAACGATGAAAAATAAAGAAATTTCCAAAAGCTTGCCTTATTATAGGAAAATGCCTAATGGGGCGGAA
GTTTATGGGGTTCATATTCTTTTACCTTTATTGAATGAAAACACCAAAGAGGTTGTAGGGACTTTGATGATTTTCTTTTC
CATTGACAGCTTCAGCAATGAAATCACTAAAAACAGGAGCGATTTGTTTTTAATTGGCGTTAAGGGTAAAGTGCTTTTGA
GCGCGAATAAGAGTTTGCAAGACAAATCTATCGCAGAAATTTATAAGAGCGTGCCTAAAGCCACCAACGAAGTGATGGCT
ATTTTAGAAAACGGCTCTAACGGCTCTAAAGCGACTTTAGAATACCTGGATCCCTTTAGCCATAAGGAAAATTTTTTAGC
CGTTGAAACCTTTAAAATGCTAGGCAAAACAGAAAGTAAAGACAATCTTAATTGGATGATCGCTTCAATCATTGAAAAAG
ACAAGGTCTATGAGCAAGTAGGATCGGTGCGTTTTATGGTGATCGTAGCGAGCGCTATCATGGTGTTAGCCTTGATTATA
GCGATCACTCTCTTAATGCGAGCGATTGTGAGCAATCGTTTGGAAGCCGTTTCTAGCACCTTATCTCATTTCTTCAAATT
ATTGAACAATCAAGCCAATTCCAGCGGTATTAAATTGGTTGAAGCGAAATCTAATGACGAATTAGGGCGCATGCAAACAG
CGATCAATAAAAATATCTTGCAAACCCAAAAAATCATGCAAGAAGACAGGCAAGCCGTCCAAGACACCATTAAAGTGGTT
TCAGATGTGAAAGCAGGGAATTTTACGGTGCGCATCACGGCTGAGCCCGCAAGCCCTGATTTGAAAGAATTGAGAAATGC
GCTAAATGGGATCATGGATTATTTGCAAGAAAGCGTAGGGACTCACATGCCAAGCATTTTCAAAATCTTTGAAAGCTATT
CTGGTTTGGATTTTAGAGGCCGGATCCAAAACGCTTCGGGTAGGGTGGAACTGGTTACTAACGCTTTAGGGCAAGAAATC
CAAAAAATGTTAGAAACTTCGTCTAATTTTGCCAAAGATTTAGCGAACGATAGCGCGAATTTAAAAGAATGCGTGCAAAA
TTTAGAAAAGGCTTCAAACTCCCAACACAAAAGCTTGATGGAAACTTCTAAAACGATAGAAAATATCACCACTTCCATTC
AAGGCGTGAGCTCTCAAAGTGAAGCCATGATTGGACAAGGGCAAGACATTAAAAGCATTGTAGAAATCATTAGAGATATT
GCCGATCAAACCAATCTTTTAGCCCTGAATGCTGCTATTGAAGCCGCAAGGGCCGGCGAGCATGGCAGAGGCTTTGCGGT
AGTGGCTGATGAAGTGAGAAAGCTCGCTGAAAGGACGCAAAAATCGCTCAGCGAGATTGAAGCCAATATTAATATCCTCG
TTCAAAGCATTTCAGACACGAGCGAGAGCATTAAAAACCAGGTTAAAGAAGTGGAAGAAATCAACGCTTCTATTGAAGCC
TTAAGATCAGTTACTGAGGGCAATCTAAAAATCGCTAGCGATTCTTTAGAAATCAGTCAAGAAATTGACAAAGTTTCTAA
CGATATTTTAGAAGATGTGAATAAAAAGCAGTTTTAA

Upstream 100 bases:

>100_bases
TTAATCCAATTTAATTTTTGATTTATGTTTAAAATACTATAATGCGGTTTAAAATTTTGCCACAAATAGGCAAAAAATTC
ATCATAGTCAAGGTTGTGTT

Downstream 100 bases:

>100_bases
TGCTCATTCATATTTGCTGTTCGGTGGATAACCTCTATTTCTTAAAAAAGGCTAAAGAGGCTTTTGTGGGTGAAAAAATG
ATAGGGTTTTTTTATAACCC

Product: methyl-accepting chemotaxis protein (tlpA)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 678; Mature: 677

Protein sequence:

>678_residues
MSKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKENALHSMQDSLHFKVKEVQGILENTYTSMGIVKEMLPKDTK
REIKIHLLKNFILANSHVVGASMFFKDREDLRFTLLRDNDTIKLVENPSLGNNPLVQKTMKNKEISKSLPYYRKMPNGAE
VYGVHILLPLLNENTKEVVGTLMIFFSIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKSIAEIYKSVPKATNEVMA
ILENGSNGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIASIIEKDKVYEQVGSVRFMVIVASAIMVLALII
AITLLMRAIVSNRLEAVSSTLSHFFKLLNNQANSSGIKLVEAKSNDELGRMQTAINKNILQTQKIMQEDRQAVQDTIKVV
SDVKAGNFTVRITAEPASPDLKELRNALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEI
QKMLETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAMIGQGQDIKSIVEIIRDI
ADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEA
LRSVTEGNLKIASDSLEISQEIDKVSNDILEDVNKKQF

Sequences:

>Translated_678_residues
MSKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKENALHSMQDSLHFKVKEVQGILENTYTSMGIVKEMLPKDTK
REIKIHLLKNFILANSHVVGASMFFKDREDLRFTLLRDNDTIKLVENPSLGNNPLVQKTMKNKEISKSLPYYRKMPNGAE
VYGVHILLPLLNENTKEVVGTLMIFFSIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKSIAEIYKSVPKATNEVMA
ILENGSNGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIASIIEKDKVYEQVGSVRFMVIVASAIMVLALII
AITLLMRAIVSNRLEAVSSTLSHFFKLLNNQANSSGIKLVEAKSNDELGRMQTAINKNILQTQKIMQEDRQAVQDTIKVV
SDVKAGNFTVRITAEPASPDLKELRNALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEI
QKMLETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAMIGQGQDIKSIVEIIRDI
ADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEA
LRSVTEGNLKIASDSLEISQEIDKVSNDILEDVNKKQF
>Mature_677_residues
SKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKENALHSMQDSLHFKVKEVQGILENTYTSMGIVKEMLPKDTKR
EIKIHLLKNFILANSHVVGASMFFKDREDLRFTLLRDNDTIKLVENPSLGNNPLVQKTMKNKEISKSLPYYRKMPNGAEV
YGVHILLPLLNENTKEVVGTLMIFFSIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKSIAEIYKSVPKATNEVMAI
LENGSNGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIASIIEKDKVYEQVGSVRFMVIVASAIMVLALIIA
ITLLMRAIVSNRLEAVSSTLSHFFKLLNNQANSSGIKLVEAKSNDELGRMQTAINKNILQTQKIMQEDRQAVQDTIKVVS
DVKAGNFTVRITAEPASPDLKELRNALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEIQ
KMLETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQSEAMIGQGQDIKSIVEIIRDIA
DQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEAL
RSVTEGNLKIASDSLEISQEIDKVSNDILEDVNKKQF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=211, Percent_Identity=34.5971563981043, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1787690, Length=285, Percent_Identity=30.5263157894737, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788195, Length=179, Percent_Identity=36.8715083798883, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1789453, Length=110, Percent_Identity=42.7272727272727, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788194, Length=204, Percent_Identity=31.3725490196078, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013163
- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF08269 Cache_2; PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 75072; Mature: 74941

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKENALHSMQDSLHFKVKEVQGI
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENTYTSMGIVKEMLPKDTKREIKIHLLKNFILANSHVVGASMFFKDREDLRFTLLRDND
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCEEEEEECCC
TIKLVENPSLGNNPLVQKTMKNKEISKSLPYYRKMPNGAEVYGVHILLPLLNENTKEVVG
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCEEEHEEEEEHHCCCHHHHHH
TLMIFFSIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKSIAEIYKSVPKATNEVMA
HHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHCHHHHHHHH
ILENGSNGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIASIIEKDKVYEQV
HHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
GSVRFMVIVASAIMVLALIIAITLLMRAIVSNRLEAVSSTLSHFFKLLNNQANSSGIKLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
EAKSNDELGRMQTAINKNILQTQKIMQEDRQAVQDTIKVVSDVKAGNFTVRITAEPASPD
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
LKELRNALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
QKMLETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQS
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAMIGQGQDIKSIVEIIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQ
HHHHCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
KSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEALRSVTEGNLKIASDSLEISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHH
EIDKVSNDILEDVNKKQF
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKGLSIGNKIILCVALIVIVCVSILGVSLNSRVKEILKENALHSMQDSLHFKVKEVQGI
CCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LENTYTSMGIVKEMLPKDTKREIKIHLLKNFILANSHVVGASMFFKDREDLRFTLLRDND
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHCCCCCCEEEEEECCC
TIKLVENPSLGNNPLVQKTMKNKEISKSLPYYRKMPNGAEVYGVHILLPLLNENTKEVVG
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCEEEHEEEEEHHCCCHHHHHH
TLMIFFSIDSFSNEITKNRSDLFLIGVKGKVLLSANKSLQDKSIAEIYKSVPKATNEVMA
HHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECCCCCCHHHHHHHHHHHCHHHHHHHH
ILENGSNGSKATLEYLDPFSHKENFLAVETFKMLGKTESKDNLNWMIASIIEKDKVYEQV
HHHCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
GSVRFMVIVASAIMVLALIIAITLLMRAIVSNRLEAVSSTLSHFFKLLNNQANSSGIKLV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEE
EAKSNDELGRMQTAINKNILQTQKIMQEDRQAVQDTIKVVSDVKAGNFTVRITAEPASPD
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
LKELRNALNGIMDYLQESVGTHMPSIFKIFESYSGLDFRGRIQNASGRVELVTNALGQEI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
QKMLETSSNFAKDLANDSANLKECVQNLEKASNSQHKSLMETSKTIENITTSIQGVSSQS
HHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCH
EAMIGQGQDIKSIVEIIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQ
HHHHCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHH
KSLSEIEANINILVQSISDTSESIKNQVKEVEEINASIEALRSVTEGNLKIASDSLEISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHH
EIDKVSNDILEDVNKKQF
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]