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The map label for this gene is cynT [H]

Identifier: 188526816

GI number: 188526816

Start: 1726

End: 2391

Strand: Reverse

Name: cynT [H]

Synonym: HPSH_00020

Alternate gene names: 188526816

Gene position: 2391-1726 (Counterclockwise)

Preceding gene: 188526819

Following gene: 188526815

Centisome position: 0.15

GC content: 40.39

Gene sequence:

>666_bases
GTGAAAGCGTTTTTAGGAGCGTTAGAGTTTCAAGAGAATGAATACGAAGAGCTTAAAGAGCTTTATGAGAGCTTAAAGAC
CAAGCAAAAGCCCCACACTTTGTTCATTTCTTGCGTGGATTCACGAGTCGTGCCCAATCTAATCACAGGCACCAAGCCGG
GCGAATTGTATGTGATTCGCAACATGGGCAATGTGATCCCCCCTAAAACAAGCTATAAAGAGTCCCTTTCTACTATGGCG
AGCGTTGAATACGCTATCGTGCATGTGGGCGTTCAAAATTTAATTATTTGCGGGCATAGCGATTGTGGGGCTTGCGGGAG
CATTCATTTAATCAATGATGAAACCACCAAAGCTAAAACCCCCTACATTGCAGACTGGATACAATTCTTAGAGCCCATTA
AAGAAGAATTAAAAAACCACCCGCAATTCAGCAACCATTTCGCCAAGCGTTCATGGCTTACAGAGCGTTTGAATGTGCGC
TTGCAACTCAACAACCTCTTAAGCTATGATTTCATTCAAGAAAGAGTAATGAATAACGAACTGAAAATTTTTGGTTGGCA
CTACATCATAGAAACAGGCAGGATTTATAATTATAATTTTGAAAGCCATTTTTTTGAGCCGATTGAAGAAACCATTAAAC
AAAGGAAAAGTCATGAAAACTTCTAA

Upstream 100 bases:

>100_bases
TAACGCCATTATAACAAAAAGAAATGCAAGAATTTTAGCTATGATAAGCGTTTTAAAAATAAAACAAATTCTAATCAAAT
GAGATTTTAAGGGTTAAAGA

Downstream 100 bases:

>100_bases
AACAAAAACCCCTAAATCCGTTTTAATCGCTGGTCCATGCGTCATTGAGAGCTTAGAAAATCTAAGAAGTATCGCTATTA
AATTACAACCCCTAGCCAAC

Product: beta-carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIRNMGNVIPPKTSYKESLSTMA
SVEYAIVHVGVQNLIICGHSDCGACGSIHLINDETTKAKTPYIADWIQFLEPIKEELKNHPQFSNHFAKRSWLTERLNVR
LQLNNLLSYDFIQERVMNNELKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF

Sequences:

>Translated_221_residues
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIRNMGNVIPPKTSYKESLSTMA
SVEYAIVHVGVQNLIICGHSDCGACGSIHLINDETTKAKTPYIADWIQFLEPIKEELKNHPQFSNHFAKRSWLTERLNVR
LQLNNLLSYDFIQERVMNNELKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF
>Mature_221_residues
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIRNMGNVIPPKTSYKESLSTMA
SVEYAIVHVGVQNLIICGHSDCGACGSIHLINDETTKAKTPYIADWIQFLEPIKEELKNHPQFSNHFAKRSWLTERLNVR
LQLNNLLSYDFIQERVMNNELKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=204, Percent_Identity=34.3137254901961, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786318, Length=208, Percent_Identity=29.3269230769231, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147564, Length=238, Percent_Identity=24.7899159663866, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115532990, Length=240, Percent_Identity=25, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324292, Length=168, Percent_Identity=32.1428571428571, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24645213, Length=244, Percent_Identity=24.5901639344262, Blast_Score=97, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 25792; Mature: 25792

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIR
CCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHCCCCCCCEEEEC
NMGNVIPPKTSYKESLSTMASVEYAIVHVGVQNLIICGHSDCGACGSIHLINDETTKAKT
CCCCCCCCCCHHHHHHHHHHHHHHHHEEECHHHEEEECCCCCCCCCEEEEECCCCCCCCC
PYIADWIQFLEPIKEELKNHPQFSNHFAKRSWLTERLNVRLQLNNLLSYDFIQERVMNNE
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCC
LKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF
EEEEEEEEEEECCEEEEECHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAFLGALEFQENEYEELKELYESLKTKQKPHTLFISCVDSRVVPNLITGTKPGELYVIR
CCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCHHHCCCCCCCEEEEC
NMGNVIPPKTSYKESLSTMASVEYAIVHVGVQNLIICGHSDCGACGSIHLINDETTKAKT
CCCCCCCCCCHHHHHHHHHHHHHHHHEEECHHHEEEECCCCCCCCCEEEEECCCCCCCCC
PYIADWIQFLEPIKEELKNHPQFSNHFAKRSWLTERLNVRLQLNNLLSYDFIQERVMNNE
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHCCC
LKIFGWHYIIETGRIYNYNFESHFFEPIEETIKQRKSHENF
EEEEEEEEEEECCEEEEECHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]