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The map label for this gene is atpD [H]

Identifier: 187930577

GI number: 187930577

Start: 3683390

End: 3684799

Strand: Reverse

Name: atpD [H]

Synonym: Rpic_3512

Alternate gene names: 187930577

Gene position: 3684799-3683390 (Counterclockwise)

Preceding gene: 187930578

Following gene: 187930576

Centisome position: 93.46

GC content: 62.84

Gene sequence:

>1410_bases
ATGAGTATCGCAAACGGAAATATCGTGCAGTGCATCGGCGCCGTGGTGGACATTCAGTTCCCGCGCGACGCGATGCCGAA
GGTCTACGACGCGCTGGTGCTGGACGACAGCAACGACGCTTCGTTCGCCGAGAAGGGCCTGACCTTCGAAGTGCAACAAC
AGCTGGGCGACGGCGTGGTGCGTACCATTGCGCTGGGTTCGTCCGACGGTCTGCGTCGCGGCATGCGCGTGGCGACCACC
GGTGCGCCGATCTCGGTGCCGGTCGGTCACGGCACGCTGGGCCGCATCATGGACGTGCTGGGTCGTCCGATTGACGAAGC
CGGCCCGATCGCCTGCGACGAAAAGCGCGCGATTCACCAGAAGGCCCCGAAGTTCGACGAGCTGTCGCCGTCGGTGGACC
TGCTGGAAACCGGCATCAAGGTGATCGACCTGGTCTGCCCGTTCGCCAAGGGCGGTAAGGTGGGTCTGTTTGGTGGCGCC
GGCGTCGGCAAGACCGTGAACATGATGGAGCTGATCAACAACATCGCCAAGCAGCACTCGGGCTTGTCGGTGTTTGCTGG
CGTGGGCGAGCGTACCCGTGAGGGCAACGACTTCTACCACGAAATGAAGGACTCCAACGTGCTCGACAAGGTGGCCATGG
TGTTCGGCCAGATGAACGAGCCGCCGGGCAACCGTCTGCGCGTGGCGCTGACCGGCCTGACGATGGCCGAGCGCTTCCGT
GACGAAGGCCGTGACATCCTGTTCTTCGTCGATAACATCTACCGCTACACGCTGGCCGGTACCGAAGTGTCGGCACTGCT
GGGCCGTATGCCTTCCGCCGTGGGCTATCAGCCGACGCTGGCTGAAGAAATGGGCAAGCTGCAGGAACGTATCACGTCGA
CCAAGACTGGCTCGATCACGTCGATCCAGGCCGTGTACGTGCCTGCCGATGACTTGACCGACCCGTCGCCGGCAACGACC
TTCCTGCACCTGGACTCGACCGTCGTGCTGTCGCGTGACATCGCTGCACTGGGTATCTACCCCGCAGTGGATCCGCTCGA
CTCGACGTCGCGCCAGCTCGACCCGCAAGTGGTTGGCCAGGAGCACTACGAAGTCGCCGACCGCGTGAAGAAGACGCTGC
AGCGCTACAAGGAACTGCGCGACATCATCGCGATTCTGGGCATGGACGAACTCTCGCCGGAAGACAAGCTGGCTGTGGGC
CGCGCCCGTAAGATCCAGCGTTTCCTGTCGCAGCCGTTCCACGTTGCAGAAGTGTTCACGGGCTCGCCGGGCAAGTACGT
GCCGCTGAAGGAAACCATCCGCGGCTTCAAGATGCTGGTGGACGGCGAGTGCGATCACCTGCCGGAACAGGCGTTCTACA
TGGTCGGCTCGATCGACGAAGCCTTCGAGAAGGCCAAGAAGCTCCAGTAA

Upstream 100 bases:

>100_bases
GACCCGTCAGGCAGCGATCACGAAGGAACTGTCCGAGATCGTCAGCGGCGCAGCTGCAGTCTGATAGCCACGGCAAAGAA
TCAAGTTATTGGAGATACAA

Downstream 100 bases:

>100_bases
GAGCAACGTCTGGCACCGCGCGTGAGCCGGGGCCAGTACTGGCTTCCTGAAGCCCCTTCAGGAAGCCGCTTTTCTGAGCA
AAGGAATCGAGATGGCAACC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MSIANGNIVQCIGAVVDIQFPRDAMPKVYDALVLDDSNDASFAEKGLTFEVQQQLGDGVVRTIALGSSDGLRRGMRVATT
GAPISVPVGHGTLGRIMDVLGRPIDEAGPIACDEKRAIHQKAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGA
GVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAERFR
DEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSITSIQAVYVPADDLTDPSPATT
FLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGQEHYEVADRVKKTLQRYKELRDIIAILGMDELSPEDKLAVG
RARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMLVDGECDHLPEQAFYMVGSIDEAFEKAKKLQ

Sequences:

>Translated_469_residues
MSIANGNIVQCIGAVVDIQFPRDAMPKVYDALVLDDSNDASFAEKGLTFEVQQQLGDGVVRTIALGSSDGLRRGMRVATT
GAPISVPVGHGTLGRIMDVLGRPIDEAGPIACDEKRAIHQKAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGA
GVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAERFR
DEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSITSIQAVYVPADDLTDPSPATT
FLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGQEHYEVADRVKKTLQRYKELRDIIAILGMDELSPEDKLAVG
RARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMLVDGECDHLPEQAFYMVGSIDEAFEKAKKLQ
>Mature_468_residues
SIANGNIVQCIGAVVDIQFPRDAMPKVYDALVLDDSNDASFAEKGLTFEVQQQLGDGVVRTIALGSSDGLRRGMRVATTG
APISVPVGHGTLGRIMDVLGRPIDEAGPIACDEKRAIHQKAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGAG
VGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAERFRD
EGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSITSIQAVYVPADDLTDPSPATTF
LHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGQEHYEVADRVKKTLQRYKELRDIIAILGMDELSPEDKLAVGR
ARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMLVDGECDHLPEQAFYMVGSIDEAFEKAKKLQ

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=472, Percent_Identity=66.9491525423729, Blast_Score=628, Evalue=1e-180,
Organism=Homo sapiens, GI50345984, Length=331, Percent_Identity=25.0755287009063, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI4757810, Length=331, Percent_Identity=25.0755287009063, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI19913424, Length=317, Percent_Identity=27.4447949526814, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI19913428, Length=371, Percent_Identity=24.7978436657682, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI19913426, Length=396, Percent_Identity=23.7373737373737, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1790170, Length=466, Percent_Identity=78.9699570815451, Blast_Score=749, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=324, Percent_Identity=29.6296296296296, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1790172, Length=340, Percent_Identity=26.4705882352941, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI25144756, Length=472, Percent_Identity=66.1016949152542, Blast_Score=619, Evalue=1e-177,
Organism=Caenorhabditis elegans, GI71988080, Length=381, Percent_Identity=25.4593175853018, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71988063, Length=381, Percent_Identity=25.4593175853018, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=350, Percent_Identity=25.4285714285714, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17565854, Length=318, Percent_Identity=27.6729559748428, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=350, Percent_Identity=24, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71988074, Length=342, Percent_Identity=23.6842105263158, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=462, Percent_Identity=64.5021645021645, Blast_Score=603, Evalue=1e-173,
Organism=Saccharomyces cerevisiae, GI6319603, Length=415, Percent_Identity=25.3012048192771, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6319370, Length=419, Percent_Identity=25.2983293556086, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=26.1802575107296, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24638766, Length=471, Percent_Identity=65.8174097664543, Blast_Score=620, Evalue=1e-178,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=62.4203821656051, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI281361666, Length=420, Percent_Identity=24.7619047619048, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646341, Length=420, Percent_Identity=24.7619047619048, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136796, Length=420, Percent_Identity=24.7619047619048, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20129479, Length=314, Percent_Identity=28.343949044586, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24583988, Length=354, Percent_Identity=25.9887005649718, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24583986, Length=354, Percent_Identity=25.9887005649718, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24583984, Length=354, Percent_Identity=25.9887005649718, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24583992, Length=325, Percent_Identity=27.0769230769231, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24658560, Length=381, Percent_Identity=24.1469816272966, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24638768, Length=98, Percent_Identity=47.9591836734694, Blast_Score=85, Evalue=9e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 51060; Mature: 50929

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIANGNIVQCIGAVVDIQFPRDAMPKVYDALVLDDSNDASFAEKGLTFEVQQQLGDGVV
CCCCCCCHHHHHHHHHEECCCCHHHHHHHHEEEEECCCCCHHHHCCCCHHHHHHHCCCCE
RTIALGSSDGLRRGMRVATTGAPISVPVGHGTLGRIMDVLGRPIDEAGPIACDEKRAIHQ
EEEEECCCHHHHHCCEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
KAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCC
GLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAERFR
CCEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHH
DEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSIT
HCCCEEEEEEEHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCE
SIQAVYVPADDLTDPSPATTFLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGQ
EEEEEEECCCCCCCCCCCEEEEEECCEEEEECCHHHHCCCCCCCCCCCHHHHCCHHHHCH
EHYEVADRVKKTLQRYKELRDIIAILGMDELSPEDKLAVGRARKIQRFLSQPFHVAEVFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHEEE
GSPGKYVPLKETIRGFKMLVDGECDHLPEQAFYMVGSIDEAFEKAKKLQ
CCCCCCCCHHHHHHHHHEEECCCCCCCCHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
SIANGNIVQCIGAVVDIQFPRDAMPKVYDALVLDDSNDASFAEKGLTFEVQQQLGDGVV
CCCCCCHHHHHHHHHEECCCCHHHHHHHHEEEEECCCCCHHHHCCCCHHHHHHHCCCCE
RTIALGSSDGLRRGMRVATTGAPISVPVGHGTLGRIMDVLGRPIDEAGPIACDEKRAIHQ
EEEEECCCHHHHHCCEEEECCCCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
KAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHS
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCC
GLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAERFR
CCEEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHH
DEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSIT
HCCCEEEEEEEHHHHHHCCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCE
SIQAVYVPADDLTDPSPATTFLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGQ
EEEEEEECCCCCCCCCCCEEEEEECCEEEEECCHHHHCCCCCCCCCCCHHHHCCHHHHCH
EHYEVADRVKKTLQRYKELRDIIAILGMDELSPEDKLAVGRARKIQRFLSQPFHVAEVFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEHEEE
GSPGKYVPLKETIRGFKMLVDGECDHLPEQAFYMVGSIDEAFEKAKKLQ
CCCCCCCCHHHHHHHHHEEECCCCCCCCHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA