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The map label for this gene is glpR [H]

Identifier: 187930393

GI number: 187930393

Start: 3480284

End: 3481057

Strand: Reverse

Name: glpR [H]

Synonym: Rpic_3326

Alternate gene names: 187930393

Gene position: 3481057-3480284 (Counterclockwise)

Preceding gene: 187930402

Following gene: 187930392

Centisome position: 88.29

GC content: 64.73

Gene sequence:

>774_bases
ATGCTTCCGCGACACCGCCAGATCCTCGAATACGTCCGCCAACACGGCGATGCCTCCGTCGACGCGCTTGCCCGCGTGCT
CGGCGTCACGACGCAAACCATCCGTCGCGATATCCGGCAGCTCGAAGACGAGCGCCTGCTCGCGCGCTATCACGGCGGCG
TCGGCCTGCCTTCGTCGGTCGAAAACATCGACTACGACCAGCGCCAGGTCCTGCACATCGACGCCAAGCGGCGTATCGCC
GAGGTCGTTGCGCGCCACGTCGAGCCCGGCCGTTCGCTCATCATCAATATTGGAACGACCACCGAAGAAGTCTCCAAGGC
ACTGGTCGGCCAGAACGGGCCCCGCGGTCTGCGTGTCATCACCAATAATCTGAACGTCGCGTCGATCCTCTCCGGCAGCC
CGGACGCGGAGGTCATTGTCGCCGGCGGCCTCGTGCGCAACCGCGACCGCGGCATCGTTGGCGAGGCCACGATCGACTTC
ATGAAGCAGTTTCGCGTCGACATCGGCATCATCGGCGTCTCCAGCATCGACGAAGACGGCACGCTGCTCGACTATGACTA
CCGTGAAGTGCGCGTCGCCCAGTCCATCATCGAGCAGTCCCGCGAAGTCTGGCTCGTGGCCGATCACTCCAAGTTCGGTC
GCCGCGCTGTTGTCCGCCTGGGCCATGTCTCGCAGATCGACAAGTTCTTCACCGACGTCCCCGTGCCTGAGCCGATGGCC
GAAGTCCTCCGCGCCGCCGAGGTGGACGTGATCGTCGCCAGCGAAACGCGCTGA

Upstream 100 bases:

>100_bases
GACGCGTTGGCGGATAGTTTAGTGAAGGGCGAAAATAAAGCAACATAGGGAATCGCCTAATCCGCTCATATGTGTTCGTT
TGTGTTCATTTCGTGACTTG

Downstream 100 bases:

>100_bases
CGTTTGATCCAGCTTCTCTGCGGTCTTCGACCGTTCCACTACAGTGAAATGACAAGGCGCGCACCTTGCGTGCTTCCCTG
TCATCCAGACTCGTCACACG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MLPRHRQILEYVRQHGDASVDALARVLGVTTQTIRRDIRQLEDERLLARYHGGVGLPSSVENIDYDQRQVLHIDAKRRIA
EVVARHVEPGRSLIINIGTTTEEVSKALVGQNGPRGLRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEATIDF
MKQFRVDIGIIGVSSIDEDGTLLDYDYREVRVAQSIIEQSREVWLVADHSKFGRRAVVRLGHVSQIDKFFTDVPVPEPMA
EVLRAAEVDVIVASETR

Sequences:

>Translated_257_residues
MLPRHRQILEYVRQHGDASVDALARVLGVTTQTIRRDIRQLEDERLLARYHGGVGLPSSVENIDYDQRQVLHIDAKRRIA
EVVARHVEPGRSLIINIGTTTEEVSKALVGQNGPRGLRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEATIDF
MKQFRVDIGIIGVSSIDEDGTLLDYDYREVRVAQSIIEQSREVWLVADHSKFGRRAVVRLGHVSQIDKFFTDVPVPEPMA
EVLRAAEVDVIVASETR
>Mature_257_residues
MLPRHRQILEYVRQHGDASVDALARVLGVTTQTIRRDIRQLEDERLLARYHGGVGLPSSVENIDYDQRQVLHIDAKRRIA
EVVARHVEPGRSLIINIGTTTEEVSKALVGQNGPRGLRVITNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEATIDF
MKQFRVDIGIIGVSSIDEDGTLLDYDYREVRVAQSIIEQSREVWLVADHSKFGRRAVVRLGHVSQIDKFFTDVPVPEPMA
EVLRAAEVDVIVASETR

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=240, Percent_Identity=48.3333333333333, Blast_Score=234, Evalue=5e-63,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=39.9209486166008, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1789059, Length=260, Percent_Identity=28.4615384615385, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789519, Length=255, Percent_Identity=27.4509803921569, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788069, Length=240, Percent_Identity=29.5833333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI226510968, Length=256, Percent_Identity=29.6875, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790753, Length=241, Percent_Identity=27.3858921161826, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787540, Length=235, Percent_Identity=28.0851063829787, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=23.4042553191489, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787063, Length=234, Percent_Identity=24.7863247863248, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=24.8031496062992, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28554; Mature: 28554

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRHRQILEYVRQHGDASVDALARVLGVTTQTIRRDIRQLEDERLLARYHGGVGLPSSV
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENIDYDQRQVLHIDAKRRIAEVVARHVEPGRSLIINIGTTTEEVSKALVGQNGPRGLRVI
CCCCCCCHHEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEE
TNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEATIDFMKQFRVDIGIIGVSSIDEDG
ECCCCEEEEECCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCC
TLLDYDYREVRVAQSIIEQSREVWLVADHSKFGRRAVVRLGHVSQIDKFFTDVPVPEPMA
CEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHH
EVLRAAEVDVIVASETR
HHHHHHCCEEEEECCCC
>Mature Secondary Structure
MLPRHRQILEYVRQHGDASVDALARVLGVTTQTIRRDIRQLEDERLLARYHGGVGLPSSV
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
ENIDYDQRQVLHIDAKRRIAEVVARHVEPGRSLIINIGTTTEEVSKALVGQNGPRGLRVI
CCCCCCCHHEEEHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEEE
TNNLNVASILSGSPDAEVIVAGGLVRNRDRGIVGEATIDFMKQFRVDIGIIGVSSIDEDG
ECCCCEEEEECCCCCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHEEEEEECCCCCCC
TLLDYDYREVRVAQSIIEQSREVWLVADHSKFGRRAVVRLGHVSQIDKFFTDVPVPEPMA
CEEECCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCHHHHHHHHHCCCCCCHHH
EVLRAAEVDVIVASETR
HHHHHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]