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The map label for this gene is murA [H]

Identifier: 187930298

GI number: 187930298

Start: 3377374

End: 3378738

Strand: Reverse

Name: murA [H]

Synonym: Rpic_3231

Alternate gene names: 187930298

Gene position: 3378738-3377374 (Counterclockwise)

Preceding gene: 187930299

Following gene: 187930297

Centisome position: 85.7

GC content: 65.93

Gene sequence:

>1365_bases
ATGGCCGAGCTTGATCCCACACCGGTTACCGTTTCAACCGATTCCGACCTTGCGCTCGCCGAGCGCCCCTCCCAAAGTGA
TCGACGAGACGTCTCGCTCATGGACAAACTGCTGATCGAAGGCAATGGCCCGCTCTCGGGCCAAATCCGCGTGTCTGGCG
CCAAGAACGCCGCGCTGCCCATCATGTGTGCCGCGCTGCTGACGGCCGAGCCGCTGGCGCTGAGCAACGTGCCGAACCTG
CAGGACGTGCGCACGATGCTCAAGCTGCTGCGCCAGATGGGCGTGGAAGGCGTGCTCGACGGTCACAACCTCACGCTCGA
CGCTGCGGCGATCCACACGCCCGAAGCTTCGTACGACCTGGTGAAGACCATGCGTGCGTCGATCCTGGTGCTTGGCCCGC
TGCTGGCGCGCTTCGGCCATGCGCGTGTGTCGCTGCCGGGCGGTTGCGGCATCGGCGCGCGTCCGGTGGATCAGCACATC
AAGGGGCTGCAATTGATGGGCGCCGAGATCGTCATCGAGCACGGCTACATTGAAGCCAAGCTTGCCGATGGCGCAAAGCG
TCTGCGCGGCGCGCGCATCGTCACCGACATGGTGACGGTCACGGGTACGGAAAACCTGCTGATGGCAGCCGCGCTTGCCG
ACGGCGAAACCGTGCTGGAAAACGCCGCGCGCGAGCCCGAGGTGACCGACCTCGCCAATCTGCTCGTGAAGATGGGTGCG
CGCATCGAGGGCATCGGCACCGACCGCCTCGTCATCCAGGGCGTTCAAGCGCTGCACGGCGCTGCGCACACGGTGATTGC
CGATCGGATCGAAGCCGGTACGTTCCTGTGCGCTGTGGCGGCGGCCGGTGGCGACGTGACGCTGCGCGCCGTGCCGCCCG
GCATTCTCGATGCCGTGCTCGACAAGCTGCGCGAAGCCGGCGTGACGCTCACCACGGGCGATGACTGGATCCGCGTGCAG
ATGACGGGCCGCCCCAAGGCCGTGAGCTTCCGCACGTCGGAATACCCGGCGTTCCCGACCGACATGCAGGCGCAGTTCAT
GATGCTCAACGCCATCGCCGAGGGCTCTGCCACAGTGACGGAGACCATCTTCGAAAACCGCTTCATGCACGTGCAGGAAC
TGAACCGCCTGGGCGCCAATATCGTGATCGATGGCAAGACCGCCGTGGTGACGGGCGTCGAGCAGTTGTCGGGCGCGACC
GTCATGGCGACCGACCTGCGTGCCTCGGCCAGCCTTGTCATCGCCGGGCTGATCGCGCAGGGCGAGACGCTGGTCGACCG
CATTTATCACCTCGACCGCGGCTACGACCGCATCGAGGACAAGCTGTCCGCTGTCGGCGCCAAGATCCGCCGCATTCAAG
CGTAA

Upstream 100 bases:

>100_bases
AGCGTCACCAGCTCGTCTATGCCGCGCTGGGTGAGCGGATGCGCGCCGAAATTCACGCGCTGTCCATGAAGACGCTCACC
CCGGCGGAGTGGCAGTCCTG

Downstream 100 bases:

>100_bases
GGTAAGGAACCCGCTGGCCATGAACGCATTCCAGTCCGCCTCCAACCAGCTCACGCTGGCGCTGTCCAAAGGGCGCATCT
TTGAAGAGACGCTGCCGTTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAELDPTPVTVSTDSDLALAERPSQSDRRDVSLMDKLLIEGNGPLSGQIRVSGAKNAALPIMCAALLTAEPLALSNVPNL
QDVRTMLKLLRQMGVEGVLDGHNLTLDAAAIHTPEASYDLVKTMRASILVLGPLLARFGHARVSLPGGCGIGARPVDQHI
KGLQLMGAEIVIEHGYIEAKLADGAKRLRGARIVTDMVTVTGTENLLMAAALADGETVLENAAREPEVTDLANLLVKMGA
RIEGIGTDRLVIQGVQALHGAAHTVIADRIEAGTFLCAVAAAGGDVTLRAVPPGILDAVLDKLREAGVTLTTGDDWIRVQ
MTGRPKAVSFRTSEYPAFPTDMQAQFMMLNAIAEGSATVTETIFENRFMHVQELNRLGANIVIDGKTAVVTGVEQLSGAT
VMATDLRASASLVIAGLIAQGETLVDRIYHLDRGYDRIEDKLSAVGAKIRRIQA

Sequences:

>Translated_454_residues
MAELDPTPVTVSTDSDLALAERPSQSDRRDVSLMDKLLIEGNGPLSGQIRVSGAKNAALPIMCAALLTAEPLALSNVPNL
QDVRTMLKLLRQMGVEGVLDGHNLTLDAAAIHTPEASYDLVKTMRASILVLGPLLARFGHARVSLPGGCGIGARPVDQHI
KGLQLMGAEIVIEHGYIEAKLADGAKRLRGARIVTDMVTVTGTENLLMAAALADGETVLENAAREPEVTDLANLLVKMGA
RIEGIGTDRLVIQGVQALHGAAHTVIADRIEAGTFLCAVAAAGGDVTLRAVPPGILDAVLDKLREAGVTLTTGDDWIRVQ
MTGRPKAVSFRTSEYPAFPTDMQAQFMMLNAIAEGSATVTETIFENRFMHVQELNRLGANIVIDGKTAVVTGVEQLSGAT
VMATDLRASASLVIAGLIAQGETLVDRIYHLDRGYDRIEDKLSAVGAKIRRIQA
>Mature_453_residues
AELDPTPVTVSTDSDLALAERPSQSDRRDVSLMDKLLIEGNGPLSGQIRVSGAKNAALPIMCAALLTAEPLALSNVPNLQ
DVRTMLKLLRQMGVEGVLDGHNLTLDAAAIHTPEASYDLVKTMRASILVLGPLLARFGHARVSLPGGCGIGARPVDQHIK
GLQLMGAEIVIEHGYIEAKLADGAKRLRGARIVTDMVTVTGTENLLMAAALADGETVLENAAREPEVTDLANLLVKMGAR
IEGIGTDRLVIQGVQALHGAAHTVIADRIEAGTFLCAVAAAGGDVTLRAVPPGILDAVLDKLREAGVTLTTGDDWIRVQM
TGRPKAVSFRTSEYPAFPTDMQAQFMMLNAIAEGSATVTETIFENRFMHVQELNRLGANIVIDGKTAVVTGVEQLSGATV
MATDLRASASLVIAGLIAQGETLVDRIYHLDRGYDRIEDKLSAVGAKIRRIQA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=57.957244655582, Blast_Score=482, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 48105; Mature: 47974

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50297 ANK_REP_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELDPTPVTVSTDSDLALAERPSQSDRRDVSLMDKLLIEGNGPLSGQIRVSGAKNAALP
CCCCCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
IMCAALLTAEPLALSNVPNLQDVRTMLKLLRQMGVEGVLDGHNLTLDAAAIHTPEASYDL
HHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCHHHH
VKTMRASILVLGPLLARFGHARVSLPGGCGIGARPVDQHIKGLQLMGAEIVIEHGYIEAK
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHEECCEEEEECCEEEEE
LADGAKRLRGARIVTDMVTVTGTENLLMAAALADGETVLENAAREPEVTDLANLLVKMGA
EHHHHHHHCCCEEEEHEEEECCCCHHEEEEHHCCCHHHHHHCCCCCCHHHHHHHHHHHCC
RIEGIGTDRLVIQGVQALHGAAHTVIADRIEAGTFLCAVAAAGGDVTLRAVPPGILDAVL
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCHHHHHHH
DKLREAGVTLTTGDDWIRVQMTGRPKAVSFRTSEYPAFPTDMQAQFMMLNAIAEGSATVT
HHHHHCCCEEEECCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHH
ETIFENRFMHVQELNRLGANIVIDGKTAVVTGVEQLSGATVMATDLRASASLVIAGLIAQ
HHHHHHCCHHHHHHHHCCCEEEECCCCEEEECHHHHCCCEEEEECCCCHHHHHHHHHHHC
GETLVDRIYHLDRGYDRIEDKLSAVGAKIRRIQA
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AELDPTPVTVSTDSDLALAERPSQSDRRDVSLMDKLLIEGNGPLSGQIRVSGAKNAALP
CCCCCCCEEEECCCCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
IMCAALLTAEPLALSNVPNLQDVRTMLKLLRQMGVEGVLDGHNLTLDAAAIHTPEASYDL
HHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEEEEECCCCHHHH
VKTMRASILVLGPLLARFGHARVSLPGGCGIGARPVDQHIKGLQLMGAEIVIEHGYIEAK
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHEECCEEEEECCEEEEE
LADGAKRLRGARIVTDMVTVTGTENLLMAAALADGETVLENAAREPEVTDLANLLVKMGA
EHHHHHHHCCCEEEEHEEEECCCCHHEEEEHHCCCHHHHHHCCCCCCHHHHHHHHHHHCC
RIEGIGTDRLVIQGVQALHGAAHTVIADRIEAGTFLCAVAAAGGDVTLRAVPPGILDAVL
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECCCHHHHHHH
DKLREAGVTLTTGDDWIRVQMTGRPKAVSFRTSEYPAFPTDMQAQFMMLNAIAEGSATVT
HHHHHCCCEEEECCCEEEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHH
ETIFENRFMHVQELNRLGANIVIDGKTAVVTGVEQLSGATVMATDLRASASLVIAGLIAQ
HHHHHHCCHHHHHHHHCCCEEEECCCCEEEECHHHHCCCEEEEECCCCHHHHHHHHHHHC
GETLVDRIYHLDRGYDRIEDKLSAVGAKIRRIQA
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]