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The map label for this gene is mntH [H]

Identifier: 187930231

GI number: 187930231

Start: 3315564

End: 3317207

Strand: Reverse

Name: mntH [H]

Synonym: Rpic_3164

Alternate gene names: 187930231

Gene position: 3317207-3315564 (Counterclockwise)

Preceding gene: 187930232

Following gene: 187930230

Centisome position: 84.14

GC content: 65.27

Gene sequence:

>1644_bases
ATGACCCAATTCGCTTCGGGCATCGACGCACCGCCACGTCATGCCGCACTCGACGACGCTCATGTGGGCGACATCCGCGG
CGCGCTCGGCACCATCGCGCATCACGATACGGGCGCTCGTAACAGCTGGCGCGCGCGTCTGCGGACGCTGCTCGCCATCC
TCGGGCCCGGCCTGATCGTGATGGTCGGCGACAACGACGCCGGCGCCTTCGGCACGTACACGCAAGCCGGGCAGAACTAC
GGCACCACGCTGTTGTGGACGCTGTTGTTGCTCATCCCCGTGCTGTACGTGAACCAGGAGATGGTGCTGCGCCTGGGCGC
CGTCACGCGCGTTGGCCATGCGCGGTTGATCTTTGCCCGCTTCGGCAGGTTCTGGGGCAGCTTCTCTGTCATCGATCTGT
TTCTGGTGAACGCGCTGACGCTCGTGACAGAGTTCATCGGTATCAGCCTGGCGCTGGAGTACCTCGGCATCCCTAGACAC
TGGGGCGTGTGTGCGGCGGCGGCGCTGGTGATGCTGGCTGCCTCCACCGGCGACTTCCGCCGCTTCGAGCGCTTTGCGCT
GGCGCTGGTGGCCGGCAGTCTCACGCTCATTCCCGTGTTCGTGATGGTCCATCCGCCAATTGGGCAGGTGGCACGCGACT
TCTTTGTGCCCGCGCTACCGGCCGGCGCACCGCTAGCGGAGGTCATGCTGCTGATCATCGCCATCGTCGGGACGACCGTG
GCGCCGTGGCAATTGTTCTTCCAACAGAGCTACGTGATCGACAAGCGCATCACCGCCCGTTTCATCCGCTATGAACGCGC
GGATCTGTGGCTGGGCATCGTCCTCGTGATTGCCGGCGCGGTGGCGATGATCGCCTTCAGCGCCCAGGCCTTTCACGGTT
CGCCAGAGTTCGGCAACTACACCGATGCGCTCGGCACGGCGCACGGTCTGGAGCGCCACTCGGGCCGCTGGGCCGGTGTC
CTGTTTGCGATTGCGCTGCTGGATGCCAGCATCATCGGCGCCTGTGCGGTGTCGTTGTCGACCGCGTATGCGATCGGCGA
CGTGTTTGCCGTGCGGCACTCGCTGCATCGCAAGCCGACGGAAGCCAAGGGCTTCTACGCGATCTACTTCGGGCTGACCT
TGCTGGCCGCAGGATTGGTGCTGACGCCCGGCGTGCCGCTCGGTTTGTTGACCAATGCAGTGCAATCGCTGGCCGGCGTG
CTGCTGCCAAGCGCGACAGTGTTCCTGCTGCTTTTGTGCAACGACAAGGCCGTGCTGGGCCCGTGGACGAACGGCCGCGC
GATGAACCTCTTCACCGGCGGTGTGGTGGCGGTGCTGGTGATGCTCTCCGTCATCCTGACGGCGGCTGTGTTGTTTCCGG
GGATCGGAGAATTCGAGATCGGCGCCATCCTGATCGGCGGTTCGCTCATCGCCGTGGTCATGTCGCTGGTGCTATGGCGC
ATCGAGCGACGCAGGCACCGGCCGCACCATCCACAGCGTGTGAGCGTGCTGGATCGCAATCACTGGACGATGCCGCCGCT
CGAGCAGCTCACGCCTGCCCGTTGGACGCCGCTCAAGCGCACGTGGATGTTTGTGCTGCGCGGCTACCTCGTGGTGGCTG
CGGGGCTGGTGCTGGTACGGATTGCCGGGTTGCTCGCCCAATGA

Upstream 100 bases:

>100_bases
GACGGCGGTCAGCCGCTTTCCAACCACGGTTACGCGGCGGCGGCTGTGCGCCTGTCGCGCACGTACTGGTAATCCAACAA
CACAAAAAAAGGAGGTCGAC

Downstream 100 bases:

>100_bases
GGCCGTAGGGAAAAGCGCAGGGAGGCCGCTTCGGCGGCCTCTCCAAGATGAGAATTGTTCTTATTATCAGCTCAACCTTC
GGGCGCACATTTGGTGACAA

Product: natural resistance-associated macrophage protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MTQFASGIDAPPRHAALDDAHVGDIRGALGTIAHHDTGARNSWRARLRTLLAILGPGLIVMVGDNDAGAFGTYTQAGQNY
GTTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFARFGRFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRH
WGVCAAAALVMLAASTGDFRRFERFALALVAGSLTLIPVFVMVHPPIGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTV
APWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGSPEFGNYTDALGTAHGLERHSGRWAGV
LFAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPTEAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGV
LLPSATVFLLLLCNDKAVLGPWTNGRAMNLFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAVVMSLVLWR
IERRRHRPHHPQRVSVLDRNHWTMPPLEQLTPARWTPLKRTWMFVLRGYLVVAAGLVLVRIAGLLAQ

Sequences:

>Translated_547_residues
MTQFASGIDAPPRHAALDDAHVGDIRGALGTIAHHDTGARNSWRARLRTLLAILGPGLIVMVGDNDAGAFGTYTQAGQNY
GTTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFARFGRFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRH
WGVCAAAALVMLAASTGDFRRFERFALALVAGSLTLIPVFVMVHPPIGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTV
APWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGSPEFGNYTDALGTAHGLERHSGRWAGV
LFAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPTEAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGV
LLPSATVFLLLLCNDKAVLGPWTNGRAMNLFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAVVMSLVLWR
IERRRHRPHHPQRVSVLDRNHWTMPPLEQLTPARWTPLKRTWMFVLRGYLVVAAGLVLVRIAGLLAQ
>Mature_546_residues
TQFASGIDAPPRHAALDDAHVGDIRGALGTIAHHDTGARNSWRARLRTLLAILGPGLIVMVGDNDAGAFGTYTQAGQNYG
TTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFARFGRFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRHW
GVCAAAALVMLAASTGDFRRFERFALALVAGSLTLIPVFVMVHPPIGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTVA
PWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGSPEFGNYTDALGTAHGLERHSGRWAGVL
FAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPTEAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGVL
LPSATVFLLLLCNDKAVLGPWTNGRAMNLFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAVVMSLVLWRI
ERRRHRPHHPQRVSVLDRNHWTMPPLEQLTPARWTPLKRTWMFVLRGYLVVAAGLVLVRIAGLLAQ

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Escherichia coli, GI1788736, Length=421, Percent_Identity=23.7529691211401, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 58958; Mature: 58827

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFASGIDAPPRHAALDDAHVGDIRGALGTIAHHDTGARNSWRARLRTLLAILGPGLIV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEE
MVGDNDAGAFGTYTQAGQNYGTTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFAR
EECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHH
FGRFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRHWGVCAAAALVMLAASTGDFR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHH
RFERFALALVAGSLTLIPVFVMVHPPIGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
APWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGSPEFGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
TDALGTAHGLERHSGRWAGVLFAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGVLLPSATVFLLLLCNDKAVLG
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEC
PWTNGRAMNLFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAVVMSLVLWR
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEECHHHHHHHHHHHHHH
IERRRHRPHHPQRVSVLDRNHWTMPPLEQLTPARWTPLKRTWMFVLRGYLVVAAGLVLVR
HHHHHCCCCCCCEEHEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAGLLAQ
HHHHHCC
>Mature Secondary Structure 
TQFASGIDAPPRHAALDDAHVGDIRGALGTIAHHDTGARNSWRARLRTLLAILGPGLIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEE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HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA