Click here to switch to the map view.

The map label for this gene is dsbC [H]

Identifier: 187930201

GI number: 187930201

Start: 3283071

End: 3283817

Strand: Reverse

Name: dsbC [H]

Synonym: Rpic_3134

Alternate gene names: 187930201

Gene position: 3283817-3283071 (Counterclockwise)

Preceding gene: 187930202

Following gene: 187930200

Centisome position: 83.29

GC content: 65.19

Gene sequence:

>747_bases
ATGTCGTTTCGTATTCGGGTGGCGGCCATCGCCTCTGCGGTGGCAGTGGCAGCCATTGGCGCGGGCTATGTATTGAGCGC
CGGTGCCGCCGAGCCCGCATTGGACAAGGTGAAGGCCACGGTGCAGAAGGCCCTGGGCCCGAACGTGGAGATCAAGAGCG
TCACCAAGTCGCCGCTGGCCGGCCTGTACGAGATCAACCTCGGCAGCCAGGTCGTCTACAGCGATGCCACCGGCCGCTAC
GTGCTCAACGGCGATCTGCTGGACACGCAGACCGCCACGAACCTCACGCAGGAGCGCCTGGCCGAGCTGAACCGCGTCAA
GTGGTCCGACCTGCCGCTGGACCGCGCCGTGAAGTGGGTCAAGGGCAACGGTGCACGCAAGATCGCCGTGTTCTCCGATC
CGAACTGCCCGTACTGCCACAAGCTGGAGCAGATGCTCACGCAGGTCGACAACGTCACCGTCTACACCTTCCTGTTCCCG
ATCCTGTCGGAAGACTCGAACACCAAGGCCAAGCAGATCTGGTGTTCGGCCGACCGCGCCAAGGCCTGGCGCGACTGGAT
GACCGCCAAGACCGCCCCGGGCGGCGCCGGCACCTGCGATACACCGCTGGAAGCCAACCTGAAGCTTGGCCAGCAACTGA
ACGTGACCGGCACGCCGGCCATCATCTTCCCGGACGGCTCGCGGGCCCCGGGCCTGATCGATGCAGCCACGCTGGAGCGT
AAGTTCGCCGCGCTCAAGAAGTCATAA

Upstream 100 bases:

>100_bases
GTGGGCATGACGCCATTTATCAAACGCTTGTTGATCAGGCACGCACTCGGCTGAGGCACTCTCAGCGGATTTGTGGTTTT
TCGGGGTTCCAGGAGTCGTT

Downstream 100 bases:

>100_bases
TTCACGCGAAGGAAGCGCCGGTCGATCCGGCGCTTTTTCTTTGGGCGCTTGCATTCAACTCACCTTTGGAGACTTGGTAT
GTCGTTTCGCGCGCTGATGC

Product: putative thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MSFRIRVAAIASAVAVAAIGAGYVLSAGAAEPALDKVKATVQKALGPNVEIKSVTKSPLAGLYEINLGSQVVYSDATGRY
VLNGDLLDTQTATNLTQERLAELNRVKWSDLPLDRAVKWVKGNGARKIAVFSDPNCPYCHKLEQMLTQVDNVTVYTFLFP
ILSEDSNTKAKQIWCSADRAKAWRDWMTAKTAPGGAGTCDTPLEANLKLGQQLNVTGTPAIIFPDGSRAPGLIDAATLER
KFAALKKS

Sequences:

>Translated_248_residues
MSFRIRVAAIASAVAVAAIGAGYVLSAGAAEPALDKVKATVQKALGPNVEIKSVTKSPLAGLYEINLGSQVVYSDATGRY
VLNGDLLDTQTATNLTQERLAELNRVKWSDLPLDRAVKWVKGNGARKIAVFSDPNCPYCHKLEQMLTQVDNVTVYTFLFP
ILSEDSNTKAKQIWCSADRAKAWRDWMTAKTAPGGAGTCDTPLEANLKLGQQLNVTGTPAIIFPDGSRAPGLIDAATLER
KFAALKKS
>Mature_247_residues
SFRIRVAAIASAVAVAAIGAGYVLSAGAAEPALDKVKATVQKALGPNVEIKSVTKSPLAGLYEINLGSQVVYSDATGRYV
LNGDLLDTQTATNLTQERLAELNRVKWSDLPLDRAVKWVKGNGARKIAVFSDPNCPYCHKLEQMLTQVDNVTVYTFLFPI
LSEDSNTKAKQIWCSADRAKAWRDWMTAKTAPGGAGTCDTPLEANLKLGQQLNVTGTPAIIFPDGSRAPGLIDAATLERK
FAALKKS

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=203, Percent_Identity=30.5418719211823, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26581; Mature: 26450

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRIRVAAIASAVAVAAIGAGYVLSAGAAEPALDKVKATVQKALGPNVEIKSVTKSPLA
CCEEEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GLYEINLGSQVVYSDATGRYVLNGDLLDTQTATNLTQERLAELNRVKWSDLPLDRAVKWV
CEEEECCCCEEEEECCCCCEEEECCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KGNGARKIAVFSDPNCPYCHKLEQMLTQVDNVTVYTFLFPILSEDSNTKAKQIWCSADRA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHEEECCHHH
KAWRDWMTAKTAPGGAGTCDTPLEANLKLGQQLNVTGTPAIIFPDGSRAPGLIDAATLER
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCHHHHHHH
KFAALKKS
HHHHHCCC
>Mature Secondary Structure 
SFRIRVAAIASAVAVAAIGAGYVLSAGAAEPALDKVKATVQKALGPNVEIKSVTKSPLA
CEEEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GLYEINLGSQVVYSDATGRYVLNGDLLDTQTATNLTQERLAELNRVKWSDLPLDRAVKWV
CEEEECCCCEEEEECCCCCEEEECCEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
KGNGARKIAVFSDPNCPYCHKLEQMLTQVDNVTVYTFLFPILSEDSNTKAKQIWCSADRA
CCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHCCCCCCHHHHEEECCHHH
KAWRDWMTAKTAPGGAGTCDTPLEANLKLGQQLNVTGTPAIIFPDGSRAPGLIDAATLER
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCCCCCCCHHHHHHH
KFAALKKS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]