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The map label for this gene is yhdH [H]

Identifier: 187930200

GI number: 187930200

Start: 3281976

End: 3282992

Strand: Reverse

Name: yhdH [H]

Synonym: Rpic_3133

Alternate gene names: 187930200

Gene position: 3282992-3281976 (Counterclockwise)

Preceding gene: 187930201

Following gene: 187930199

Centisome position: 83.27

GC content: 69.71

Gene sequence:

>1017_bases
ATGTCGTTTCGCGCGCTGATGCTGGAAAAGCAGGATGGCGGGCCGCTGGCCCACATCGTCGACCTCGATGACGCGGCGTT
GTCCGCACCCGAAGCGCTGGCCAACGAGGTGACCGCCGGCGATGTGCTGATCCGCGTGGACTGGTCGACCATCAATTACA
AGGACGGCCTGGCCATCACCGGCAAAGGCCCGGTCGTGCGCAAATGGCCGATGGTGGCCGGCATCGACGGCGCGGGTGTC
GTGCTCGATTCCTCGCATCCGGACTGGAGGACGGGCGATGCGGTCGTGCTCAACGGCTGGGGCGTCGGCGAGACGCATTG
GGGGTGCCTCGCCCAGCAGGCGCGGCTTTCGGGCAATTGGCTGGTGGCATTGCCGGCGGGGCTCGACGCGCGGCAGGCCA
TGGCGATCGGCACGGCCGGCTACACGGCGATGCTGTCGGTGCTGGCGTTGGAGCGTGCCGGCGTGAAACCGGGCGACGGC
GAGGTCCTGGTGACGGGCGCATCGGGCGGCGTGGGCTCGATCGCCATCGCGCTGCTCGGCAAGCTGGGCTACCGCGTGGT
GGCGTCCACCGGCAAGACGAGCGAGGCCGATTTCCTGCAGGCGCTGGGCGCGACGGAGGTGATCGACCGCGCCGAGCTTT
CCGCCCCCGGCAAGCCGTTGCAGAAGGAACGCTGGGCGGCGGTGGTCGATTCGGTGGGCTCGCACACGCTGGCGAACGCG
TGCGCACAGGTGCGCTATGGCGGTGTGGTCACGGCGTGCGGGCTTGCGCAGGGGATGGATTTTCCGGCCACGGTCGCACC
GTTCATCCTGCGTGGCGTGACCCTGTGCGGGATCGACAGCGTGATGGCGCCACGCGCGCTGCGCCAGACCGCGTGGCAGC
GTCTGGCCGCCGATCTGCTGCCCGATCGCCTGGCCGCCATCACGCGCGAGGTGACGCTTTCCGAGGCCATCGACGCAGCC
CACGACATCATGGCCGGCAAGATGCGCGGGCGCGTCGTGGTCGACGTCAACCGATAG

Upstream 100 bases:

>100_bases
CGCCGCGCTCAAGAAGTCATAATTCACGCGAAGGAAGCGCCGGTCGATCCGGCGCTTTTTCTTTGGGCGCTTGCATTCAA
CTCACCTTTGGAGACTTGGT

Downstream 100 bases:

>100_bases
GCTGGCAGGCCGGTTTGCGGACGATTTGGCTTCGGCGGCGTGGGACGGCAACGCTACAATGTCCGCCATGAAGCCGATCC
GCTACACCATTGCCCCCGCC

Product: quinone oxidoreductase, YhdH/YhfP family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSFRALMLEKQDGGPLAHIVDLDDAALSAPEALANEVTAGDVLIRVDWSTINYKDGLAITGKGPVVRKWPMVAGIDGAGV
VLDSSHPDWRTGDAVVLNGWGVGETHWGCLAQQARLSGNWLVALPAGLDARQAMAIGTAGYTAMLSVLALERAGVKPGDG
EVLVTGASGGVGSIAIALLGKLGYRVVASTGKTSEADFLQALGATEVIDRAELSAPGKPLQKERWAAVVDSVGSHTLANA
CAQVRYGGVVTACGLAQGMDFPATVAPFILRGVTLCGIDSVMAPRALRQTAWQRLAADLLPDRLAAITREVTLSEAIDAA
HDIMAGKMRGRVVVDVNR

Sequences:

>Translated_338_residues
MSFRALMLEKQDGGPLAHIVDLDDAALSAPEALANEVTAGDVLIRVDWSTINYKDGLAITGKGPVVRKWPMVAGIDGAGV
VLDSSHPDWRTGDAVVLNGWGVGETHWGCLAQQARLSGNWLVALPAGLDARQAMAIGTAGYTAMLSVLALERAGVKPGDG
EVLVTGASGGVGSIAIALLGKLGYRVVASTGKTSEADFLQALGATEVIDRAELSAPGKPLQKERWAAVVDSVGSHTLANA
CAQVRYGGVVTACGLAQGMDFPATVAPFILRGVTLCGIDSVMAPRALRQTAWQRLAADLLPDRLAAITREVTLSEAIDAA
HDIMAGKMRGRVVVDVNR
>Mature_337_residues
SFRALMLEKQDGGPLAHIVDLDDAALSAPEALANEVTAGDVLIRVDWSTINYKDGLAITGKGPVVRKWPMVAGIDGAGVV
LDSSHPDWRTGDAVVLNGWGVGETHWGCLAQQARLSGNWLVALPAGLDARQAMAIGTAGYTAMLSVLALERAGVKPGDGE
VLVTGASGGVGSIAIALLGKLGYRVVASTGKTSEADFLQALGATEVIDRAELSAPGKPLQKERWAAVVDSVGSHTLANAC
AQVRYGGVVTACGLAQGMDFPATVAPFILRGVTLCGIDSVMAPRALRQTAWQRLAADLLPDRLAAITREVTLSEAIDAAH
DIMAGKMRGRVVVDVNR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789651, Length=335, Percent_Identity=54.3283582089552, Blast_Score=353, Evalue=8e-99,
Organism=Caenorhabditis elegans, GI71988145, Length=358, Percent_Identity=26.536312849162, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319621, Length=373, Percent_Identity=26.2734584450402, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323961, Length=371, Percent_Identity=25.0673854447439, Blast_Score=73, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=341, Percent_Identity=26.9794721407625, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=353, Percent_Identity=25.4957507082153, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR014188 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35121; Mature: 34990

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRALMLEKQDGGPLAHIVDLDDAALSAPEALANEVTAGDVLIRVDWSTINYKDGLAIT
CCCCEEEEEECCCCCEEEEEECCHHHHCCHHHHHHCCCCCCEEEEEECCEEECCCCEEEE
GKGPVVRKWPMVAGIDGAGVVLDSSHPDWRTGDAVVLNGWGVGETHWGCLAQQARLSGNW
CCCCCEEECCEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCE
LVALPAGLDARQAMAIGTAGYTAMLSVLALERAGVKPGDGEVLVTGASGGVGSIAIALLG
EEEECCCCCHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
KLGYRVVASTGKTSEADFLQALGATEVIDRAELSAPGKPLQKERWAAVVDSVGSHTLANA
HHCCEEEECCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHH
CAQVRYGGVVTACGLAQGMDFPATVAPFILRGVTLCGIDSVMAPRALRQTAWQRLAADLL
HHHHHCCCEEEEHHHHCCCCCCHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
PDRLAAITREVTLSEAIDAAHDIMAGKMRGRVVVDVNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
>Mature Secondary Structure 
SFRALMLEKQDGGPLAHIVDLDDAALSAPEALANEVTAGDVLIRVDWSTINYKDGLAIT
CCCEEEEEECCCCCEEEEEECCHHHHCCHHHHHHCCCCCCEEEEEECCEEECCCCEEEE
GKGPVVRKWPMVAGIDGAGVVLDSSHPDWRTGDAVVLNGWGVGETHWGCLAQQARLSGNW
CCCCCEEECCEEECCCCCCEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCE
LVALPAGLDARQAMAIGTAGYTAMLSVLALERAGVKPGDGEVLVTGASGGVGSIAIALLG
EEEECCCCCHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHH
KLGYRVVASTGKTSEADFLQALGATEVIDRAELSAPGKPLQKERWAAVVDSVGSHTLANA
HHCCEEEECCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHH
CAQVRYGGVVTACGLAQGMDFPATVAPFILRGVTLCGIDSVMAPRALRQTAWQRLAADLL
HHHHHCCCEEEEHHHHCCCCCCHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
PDRLAAITREVTLSEAIDAAHDIMAGKMRGRVVVDVNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1370469; 9278503 [H]