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The map label for this gene is pyrF

Identifier: 187930086

GI number: 187930086

Start: 3146081

End: 3146896

Strand: Reverse

Name: pyrF

Synonym: Rpic_3018

Alternate gene names: 187930086

Gene position: 3146896-3146081 (Counterclockwise)

Preceding gene: 187930088

Following gene: 187930085

Centisome position: 79.82

GC content: 65.2

Gene sequence:

>816_bases
ATGCGATTTACCGAACAACTGGCTGCCGCCTGGCAACGCAACAACTCCCTGCTGTGCGTCGGGCTCGATCCTGACCCGGC
ACGCCTGCCGGCGTCGCTGACCGGCACGGGCGGAGCGATCTTCTCATTCTGCCGCGCCATCGTGGACGCGACCGCCGACC
TTGTCTGCGCGTTCAAGCCGCAGATCGCCTACTTTGCCTCGCAGCGCGCTGAAGACCAGCTCGAGCAGCTCATCAGCTAC
ATCCACGAAGCCTATCCGGGCGTTCCCGTCATTCTTGATGCCAAGCGCGGCGATATCGGCTCAACCGCCGAGCACTACGC
CAAGGAAGCCTTCGAGCGCTACCAGGCCGACGCCGTCACCGTCAGCCCGTACATGGGTTTTGACTCGATGCAGCCGTATC
TCGCGCACGCCGACAAGGGCGTGATCGTGCTGTGCCGCACGTCCAACGCCGGCGGCAGCGATGTGCAGTTCCTCGAAACC
GACGGCCGCCCTGTCTATCAGGTCGTGGCCGAACGTGCGCGCGACGTGTGGAACACCAGCGGCCAGATGGGCCTGGTGGT
GGGTGCGACCTTTCCCGAAGAGATTGCCAAGGTGCGGGAGATTGTCGGCGACATGCCGCTGCTGATTCCGGGCGTTGGCG
CCCAGGGAGGCGACATCGAAGCCACGGTGCGCGCCGGCCGCACGGCCGACGGTACCGGCATGATGATCAACTCGTCGCGG
GCCATTCTCTACGCGAGCACCGACAGCGATTTCGCCGATGCCGCTCGCCGCGTGGCGCTTGCCACCCGAGACCAGATCAA
CCAGTTCCGCAACTGA

Upstream 100 bases:

>100_bases
GGCCGATGCCACGTCCGGAAGATGCCGCCACCGGGCCGCCCGACGGGTAAAATGAACGCAAGTCATGCGGCCGTCCGGCC
GCTCTCACATTCCCGACACC

Downstream 100 bases:

>100_bases
TCCGCTCTGTCGGTCCGGTTGCGGTAAGAGCGAGGACGCCATGACCACGCATCCGCACGGCCCCGTTGCCGGTACGCACC
GGGAAGAGACCGGCAAGGAC

Product: orotidine 5'-phosphate decarboxylase

Products: NA

Alternate protein names: OMP decarboxylase; OMPDCase; OMPdecase

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MRFTEQLAAAWQRNNSLLCVGLDPDPARLPASLTGTGGAIFSFCRAIVDATADLVCAFKPQIAYFASQRAEDQLEQLISY
IHEAYPGVPVILDAKRGDIGSTAEHYAKEAFERYQADAVTVSPYMGFDSMQPYLAHADKGVIVLCRTSNAGGSDVQFLET
DGRPVYQVVAERARDVWNTSGQMGLVVGATFPEEIAKVREIVGDMPLLIPGVGAQGGDIEATVRAGRTADGTGMMINSSR
AILYASTDSDFADAARRVALATRDQINQFRN

Sequences:

>Translated_271_residues
MRFTEQLAAAWQRNNSLLCVGLDPDPARLPASLTGTGGAIFSFCRAIVDATADLVCAFKPQIAYFASQRAEDQLEQLISY
IHEAYPGVPVILDAKRGDIGSTAEHYAKEAFERYQADAVTVSPYMGFDSMQPYLAHADKGVIVLCRTSNAGGSDVQFLET
DGRPVYQVVAERARDVWNTSGQMGLVVGATFPEEIAKVREIVGDMPLLIPGVGAQGGDIEATVRAGRTADGTGMMINSSR
AILYASTDSDFADAARRVALATRDQINQFRN
>Mature_271_residues
MRFTEQLAAAWQRNNSLLCVGLDPDPARLPASLTGTGGAIFSFCRAIVDATADLVCAFKPQIAYFASQRAEDQLEQLISY
IHEAYPGVPVILDAKRGDIGSTAEHYAKEAFERYQADAVTVSPYMGFDSMQPYLAHADKGVIVLCRTSNAGGSDVQFLET
DGRPVYQVVAERARDVWNTSGQMGLVVGATFPEEIAKVREIVGDMPLLIPGVGAQGGDIEATVRAGRTADGTGMMINSSR
AILYASTDSDFADAARRVALATRDQINQFRN

Specific function: Unknown

COG id: COG0284

COG function: function code F; Orotidine-5'-phosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OMP decarboxylase family. Type 2 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRF_RALPJ (B2UCD6)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001900573.1
- GeneID:   6286972
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_3018
- HOGENOM:   HBG348634
- OMA:   LLCRTSN
- ProtClustDB:   PRK00125
- HAMAP:   MF_01215
- InterPro:   IPR013785
- InterPro:   IPR018089
- InterPro:   IPR011995
- InterPro:   IPR001754
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00934
- TIGRFAMs:   TIGR02127

Pfam domain/function: PF00215 OMPdecase; SSF51366 RibP_bind_barrel

EC number: =4.1.1.23

Molecular weight: Translated: 29219; Mature: 29219

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00156 OMPDECASE

Important sites: ACT_SITE 95-95

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTEQLAAAWQRNNSLLCVGLDPDPARLPASLTGTGGAIFSFCRAIVDATADLVCAFKP
CCHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCC
QIAYFASQRAEDQLEQLISYIHEAYPGVPVILDAKRGDIGSTAEHYAKEAFERYQADAVT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEE
VSPYMGFDSMQPYLAHADKGVIVLCRTSNAGGSDVQFLETDGRPVYQVVAERARDVWNTS
ECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
GQMGLVVGATFPEEIAKVREIVGDMPLLIPGVGAQGGDIEATVRAGRTADGTGMMINSSR
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCC
AILYASTDSDFADAARRVALATRDQINQFRN
EEEEEECCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRFTEQLAAAWQRNNSLLCVGLDPDPARLPASLTGTGGAIFSFCRAIVDATADLVCAFKP
CCHHHHHHHHHHCCCCEEEEECCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCC
QIAYFASQRAEDQLEQLISYIHEAYPGVPVILDAKRGDIGSTAEHYAKEAFERYQADAVT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEE
VSPYMGFDSMQPYLAHADKGVIVLCRTSNAGGSDVQFLETDGRPVYQVVAERARDVWNTS
ECCCCCCCCCCHHHHCCCCCEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCC
GQMGLVVGATFPEEIAKVREIVGDMPLLIPGVGAQGGDIEATVRAGRTADGTGMMINSSR
CCEEEEEECCCHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCC
AILYASTDSDFADAARRVALATRDQINQFRN
EEEEEECCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA