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The map label for this gene is mntH [H]

Identifier: 187930017

GI number: 187930017

Start: 3068336

End: 3069979

Strand: Reverse

Name: mntH [H]

Synonym: Rpic_2949

Alternate gene names: 187930017

Gene position: 3069979-3068336 (Counterclockwise)

Preceding gene: 187930018

Following gene: 187930015

Centisome position: 77.87

GC content: 65.02

Gene sequence:

>1644_bases
ATGACCCAACTGACTTCGGGCATCGACACACCACCACGTCATGCCGCTCTCGACGACGCCCATGTGGGCGACATCCGTGG
GGCGCTCGGCACCATCGCCCACCATGACACCGGCGCGCGTGATAGCTGGCGTGCGCGCTTGCGTACATTGCTCGCCATCC
TCGGGCCCGGCCTGATCGTGATGGTCGGCGACAACGATGCCGGCGCCTTCGGCACCTACACGCAGGCCGGGCAGAACTAC
GGCACCACGCTGCTCTGGACGTTGCTGCTGCTGATCCCTGTGCTGTACGTGAACCAGGAGATGGTGCTGCGCCTGGGCGC
CGTCACGCGCGTCGGCCATGCGCGGCTGATCTTTGCGCGCTTCGGCAAGTTCTGGGGCAGCTTCTCCGTCATCGACCTGT
TTCTGGTGAACGCGCTGACCTTGGTGACGGAATTCATCGGCATCAGCCTGGCGCTGGAGTATCTCGGCATCCCGCGTCAT
TGGGGCGTGTGTGCAGCGGCCGCGCTGGTGATGCTGGCCGCCTCCACGGGCGACTTCCGCCGCTTCGAGCGCTTTGCGCT
GCTGCTGGTGGCGGGCAGCCTCACGCTTATTCCCATCTTTGTGATGGTGCACCCGCCGATGGGGCAGGTGGCGCGCGACT
TCTTCGTGCCTGCTCTACCGGCCGGTGCACCGCTGGCGGAGGTAATGCTGCTGATCATCGCCATCGTGGGGACGACGGTG
GCGCCGTGGCAGTTGTTCTTCCAGCAGAGCTACGTGATCGACAAGCGGATCACCGCGCGCTTCATCCGCTATGAGCGAGC
GGACCTGTGGCTGGGCATCGTGCTCGTGATTGCCGGTGCCGTGGCGATGATCGCCTTCAGCGCGCAGGCCTTCCACGGTA
CGCCAGAGTTTGGCAACTACACCGATGCACTGGGCACGGCGAAAGGGTTGGAAGCGCACTCGGGCCGCTGGGCCGGTGTG
CTGTTTGCGATCGCGCTGTTGGACGCCAGCATCATCGGCGCATGCGCGGTGTCGCTGTCCACGGCCTATGCTATCGGCGA
TGTGTTCGCTGTACGGCATTCGCTGCATCGCAAGCCGACGGAGGCCAAGGGTTTCTATGCGATTTACTTCGGGCTGACGC
TGCTGGCCGCAGGGTTGGTGCTGACGCCGGGTGTGCCGCTCGGGCTGTTGACCAACGCGGTGCAATCACTGGCCGGCGTG
CTGCTGCCGAGCGCGACGGTGTTCCTGCTGCTGTTGTGCAATGACAAGGCTGTGCTGGGCCCCTGGACGAACGGCCGCGC
GATGAACATCTTCACCGGCGGTGTGGTGGCGGTGCTGGTGATGCTCTCCGTCATCCTGACGGCGGCGGTGCTGTTTCCCG
GCATCGGCGAATTCGAGATCGGCGCGATCCTGATCGGCGGTTCGCTCATCGCCATTGTCATGTCGCTGGTGTTGTGGCAC
ATCGAGCGGCGCAGTCATCGACCCCAGCATCCACTGCGCGTGAGCGTGCTCGATCGCGACCACTGGACCATGCCGCCGCT
GGAGCAGCTCACGCCAGCACGTTGGACACCGCTCAAGCGCACGTGGATGTTTGTGCTGCGGGCTTATCTCGTGGTGGCCG
CTGGACTGGTGCTGGTGCGGATCGCTGGGCTGGTGACGGGATGA

Upstream 100 bases:

>100_bases
CTCTCCAACCACGGCTACGCTGCCGCTGCCGTCCGGCTGTCGCGCACCTATTGGTAACCGGTGGGTCATCCAATCACCCA
ATAACAAATCGGAGGTCGCT

Downstream 100 bases:

>100_bases
GGCTAGGCCAACAGCCTACATACATCTTGCCTCACGCGCCGGGTAGCTGAAGCGGTTTTGAGTCCAGTTTGCCAACGGGG
ACAAGGGGTTGCTCGCAATC

Product: natural resistance-associated macrophage protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MTQLTSGIDTPPRHAALDDAHVGDIRGALGTIAHHDTGARDSWRARLRTLLAILGPGLIVMVGDNDAGAFGTYTQAGQNY
GTTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFARFGKFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRH
WGVCAAAALVMLAASTGDFRRFERFALLLVAGSLTLIPIFVMVHPPMGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTV
APWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGTPEFGNYTDALGTAKGLEAHSGRWAGV
LFAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPTEAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGV
LLPSATVFLLLLCNDKAVLGPWTNGRAMNIFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAIVMSLVLWH
IERRSHRPQHPLRVSVLDRDHWTMPPLEQLTPARWTPLKRTWMFVLRAYLVVAAGLVLVRIAGLVTG

Sequences:

>Translated_547_residues
MTQLTSGIDTPPRHAALDDAHVGDIRGALGTIAHHDTGARDSWRARLRTLLAILGPGLIVMVGDNDAGAFGTYTQAGQNY
GTTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFARFGKFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRH
WGVCAAAALVMLAASTGDFRRFERFALLLVAGSLTLIPIFVMVHPPMGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTV
APWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGTPEFGNYTDALGTAKGLEAHSGRWAGV
LFAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPTEAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGV
LLPSATVFLLLLCNDKAVLGPWTNGRAMNIFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAIVMSLVLWH
IERRSHRPQHPLRVSVLDRDHWTMPPLEQLTPARWTPLKRTWMFVLRAYLVVAAGLVLVRIAGLVTG
>Mature_546_residues
TQLTSGIDTPPRHAALDDAHVGDIRGALGTIAHHDTGARDSWRARLRTLLAILGPGLIVMVGDNDAGAFGTYTQAGQNYG
TTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFARFGKFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRHW
GVCAAAALVMLAASTGDFRRFERFALLLVAGSLTLIPIFVMVHPPMGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTVA
PWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGTPEFGNYTDALGTAKGLEAHSGRWAGVL
FAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPTEAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGVL
LPSATVFLLLLCNDKAVLGPWTNGRAMNIFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAIVMSLVLWHI
ERRSHRPQHPLRVSVLDRDHWTMPPLEQLTPARWTPLKRTWMFVLRAYLVVAAGLVLVRIAGLVTG

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NRAMP family [H]

Homologues:

Organism=Escherichia coli, GI1788736, Length=418, Percent_Identity=23.9234449760766, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 58813; Mature: 58682

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLTSGIDTPPRHAALDDAHVGDIRGALGTIAHHDTGARDSWRARLRTLLAILGPGLIV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEE
MVGDNDAGAFGTYTQAGQNYGTTLLWTLLLLIPVLYVNQEMVLRLGAVTRVGHARLIFAR
EECCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHH
FGKFWGSFSVIDLFLVNALTLVTEFIGISLALEYLGIPRHWGVCAAAALVMLAASTGDFR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHH
RFERFALLLVAGSLTLIPIFVMVHPPMGQVARDFFVPALPAGAPLAEVMLLIIAIVGTTV
HHHHHHHHHHHCHHHHHHHHEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
APWQLFFQQSYVIDKRITARFIRYERADLWLGIVLVIAGAVAMIAFSAQAFHGTPEFGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TDALGTAKGLEAHSGRWAGVLFAIALLDASIIGACAVSLSTAYAIGDVFAVRHSLHRKPT
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
EAKGFYAIYFGLTLLAAGLVLTPGVPLGLLTNAVQSLAGVLLPSATVFLLLLCNDKAVLG
CCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHEEEEECCCEEEC
PWTNGRAMNIFTGGVVAVLVMLSVILTAAVLFPGIGEFEIGAILIGGSLIAIVMSLVLWH
CCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEECHHHHHHHHHHHHHH
IERRSHRPQHPLRVSVLDRDHWTMPPLEQLTPARWTPLKRTWMFVLRAYLVVAAGLVLVR
HHHHCCCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAGLVTG
HHHHHCC
>Mature Secondary Structure 
TQLTSGIDTPPRHAALDDAHVGDIRGALGTIAHHDTGARDSWRARLRTLLAILGPGLIV
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEE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HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA