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The map label for this gene is btuE [C]

Identifier: 187929978

GI number: 187929978

Start: 3023397

End: 3023894

Strand: Reverse

Name: btuE [C]

Synonym: Rpic_2910

Alternate gene names: 187929978

Gene position: 3023894-3023397 (Counterclockwise)

Preceding gene: 187929979

Following gene: 187929967

Centisome position: 76.7

GC content: 61.04

Gene sequence:

>498_bases
ATGAGTGACGTCTATGCATTCGAGGCCGATTCGTTAACCGGCCAGCGCGTGCCGCTGTCGCAGTACAAGGGCAAGGTCCT
GCTGATCGTCAACACGGCGAGCAAGTGCGGATTCACGCCGCAGTACGCGGGGCTGGAGGCGGTGTACAAGCGGCTGCACG
ACAAAGGGCTAGAGGTGCTCGGCTTTCCGTGCAACCAGTTCGGCAAGCAGGAACCGGGCGGCGAAGACGAGATCGGCGCC
TTCTGCGAAAAGAACTACGGCGTCTCGTTTCCGATGTTCGGCAAGATCGACGTGAATGGCTCCAACGCGCATCCGCTCTA
CAAGTGGCTGACCTCGGAAAAGCCCGGCGTGCTCGGTATCGGAGCCATCAAATGGAATTTCACCAAGTTCCTGCTGCGCC
GCGACGGCACGGTCTACAAGCGCTACGCGCCCATGACCAAGCCGGAAGAGATTGCCGACGATATTGAGCGGCTGCTGGCG
GAGCCCGATCCCGCCTGA

Upstream 100 bases:

>100_bases
CACTGACCTGCATCTCCCAACGGCCCGCCCCGCGCGGGCCGTTACAATTCCGGCCAGATGCCGGAGCATTTCCGTTCCCG
CAACCATCCGGAGAGTAGCC

Downstream 100 bases:

>100_bases
CGTTGCGGTCGTCAATCCGACGAGCCTCGCACCTTGCGCATGAAATCCGCCAGCGAGCGCTCGGCGGATTCGGCAAAGTG
GCGCTCCAGAATGTCGACCT

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MSDVYAFEADSLTGQRVPLSQYKGKVLLIVNTASKCGFTPQYAGLEAVYKRLHDKGLEVLGFPCNQFGKQEPGGEDEIGA
FCEKNYGVSFPMFGKIDVNGSNAHPLYKWLTSEKPGVLGIGAIKWNFTKFLLRRDGTVYKRYAPMTKPEEIADDIERLLA
EPDPA

Sequences:

>Translated_165_residues
MSDVYAFEADSLTGQRVPLSQYKGKVLLIVNTASKCGFTPQYAGLEAVYKRLHDKGLEVLGFPCNQFGKQEPGGEDEIGA
FCEKNYGVSFPMFGKIDVNGSNAHPLYKWLTSEKPGVLGIGAIKWNFTKFLLRRDGTVYKRYAPMTKPEEIADDIERLLA
EPDPA
>Mature_164_residues
SDVYAFEADSLTGQRVPLSQYKGKVLLIVNTASKCGFTPQYAGLEAVYKRLHDKGLEVLGFPCNQFGKQEPGGEDEIGAF
CEKNYGVSFPMFGKIDVNGSNAHPLYKWLTSEKPGVLGIGAIKWNFTKFLLRRDGTVYKRYAPMTKPEEIADDIERLLAE
PDPA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=155, Percent_Identity=47.0967741935484, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI90903240, Length=155, Percent_Identity=47.0967741935484, Blast_Score=137, Evalue=4e-33,
Organism=Homo sapiens, GI15618997, Length=160, Percent_Identity=43.75, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI192455698, Length=162, Percent_Identity=39.5061728395062, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=47.3282442748092, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI4557629, Length=183, Percent_Identity=36.6120218579235, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI41406084, Length=188, Percent_Identity=37.2340425531915, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI6006001, Length=177, Percent_Identity=37.2881355932203, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI33186887, Length=178, Percent_Identity=33.7078651685393, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI32967607, Length=179, Percent_Identity=31.8435754189944, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788003, Length=171, Percent_Identity=44.4444444444444, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=163, Percent_Identity=50.920245398773, Blast_Score=156, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=48.7654320987654, Blast_Score=151, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71993584, Length=160, Percent_Identity=40, Blast_Score=127, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=41.1042944785276, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=182, Percent_Identity=35.1648351648352, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=182, Percent_Identity=33.5164835164835, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71993573, Length=97, Percent_Identity=37.1134020618557, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71999642, Length=75, Percent_Identity=41.3333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507603, Length=108, Percent_Identity=37.037037037037, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=57.1428571428571, Blast_Score=201, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=53.125, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322826, Length=162, Percent_Identity=45.0617283950617, Blast_Score=155, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=46.25, Blast_Score=143, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=46.25, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=46.25, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=42.1383647798742, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18329; Mature: 18198

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVYAFEADSLTGQRVPLSQYKGKVLLIVNTASKCGFTPQYAGLEAVYKRLHDKGLEVL
CCCCEEEECCCCCCCCCCHHHHCCEEEEEEECCHHCCCCCCCCCHHHHHHHHHHCCCEEE
GFPCNQFGKQEPGGEDEIGAFCEKNYGVSFPMFGKIDVNGSNAHPLYKWLTSEKPGVLGI
ECCHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCEEEE
GAIKWNFTKFLLRRDGTVYKRYAPMTKPEEIADDIERLLAEPDPA
EEEHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SDVYAFEADSLTGQRVPLSQYKGKVLLIVNTASKCGFTPQYAGLEAVYKRLHDKGLEVL
CCCEEEECCCCCCCCCCHHHHCCEEEEEEECCHHCCCCCCCCCHHHHHHHHHHCCCEEE
GFPCNQFGKQEPGGEDEIGAFCEKNYGVSFPMFGKIDVNGSNAHPLYKWLTSEKPGVLGI
ECCHHHHCCCCCCCCCHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCEEEE
GAIKWNFTKFLLRRDGTVYKRYAPMTKPEEIADDIERLLAEPDPA
EEEHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]