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The map label for this gene is 187929967

Identifier: 187929967

GI number: 187929967

Start: 3012910

End: 3013467

Strand: Reverse

Name: 187929967

Synonym: Rpic_2899

Alternate gene names: NA

Gene position: 3013467-3012910 (Counterclockwise)

Preceding gene: 187929978

Following gene: 187929961

Centisome position: 76.43

GC content: 68.46

Gene sequence:

>558_bases
GTGGGCAACCGCTTATCGAAGATCGCCACACGCACCGGCGACGACGGCACCACCGGCCTCGGCGACGGTAGCCGCACGGC
CAAGGACAGCCTGCGCATCGCCGCCATCGGCGACGTCGACGAGCTGAACTCGCACATCGGCGTGCTGCTGACGGAAACGC
TGCCCGACGGCGTGCGCACGGCGCTCACCGCCATCCAGCACGACCTGTTCGATCTGGGTGGCGAACTCTGCATTCCGGGC
TACACGATGGTGACGACCGCGCACGTGTTGCGGCTCGACCAATGGCTGGCCGACTACAACGCCGATCTTCCGCGGTTGGC
CGAATTCATCCTGCCCGGCGGCAGCCGCGCTGCGGCCCAGGCGCATGTCTGCCGCACCGTCGCGCGCCGTGCCGAGCGCA
GCATCGTCGCACTCGGCCGCGCCGAGACCATTGGCGAGGCGCCGCGCCAATACGTCAATCGACTGTCGGACCTGCTGTTC
GTGCTGGCGCGCGTGCTCAATCGCGCAGATGGCGGCACGGACGTCCTCTGGAAACGCGACGAGCACAAGCCGGCGTAA

Upstream 100 bases:

>100_bases
GCGGTCTGAAGCCGGCTCGGGCTGTCATTCTAACGCCGGGGTCGTGCCGCCCTTGCGATAATGGCGCCACCAACATTGAC
GCGATACAGGGAGACGCACC

Downstream 100 bases:

>100_bases
TCACCGTCGGCACCAAACAAAACGGCCCGGCGAGTGACGGCAACTCGCCGGGCCATTTTCTTGCAGCGCTGACTTAGTTC
ACGCTCGTTGGTGTCGTCGT

Product: ATP/cobalamin adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MGNRLSKIATRTGDDGTTGLGDGSRTAKDSLRIAAIGDVDELNSHIGVLLTETLPDGVRTALTAIQHDLFDLGGELCIPG
YTMVTTAHVLRLDQWLADYNADLPRLAEFILPGGSRAAAQAHVCRTVARRAERSIVALGRAETIGEAPRQYVNRLSDLLF
VLARVLNRADGGTDVLWKRDEHKPA

Sequences:

>Translated_185_residues
MGNRLSKIATRTGDDGTTGLGDGSRTAKDSLRIAAIGDVDELNSHIGVLLTETLPDGVRTALTAIQHDLFDLGGELCIPG
YTMVTTAHVLRLDQWLADYNADLPRLAEFILPGGSRAAAQAHVCRTVARRAERSIVALGRAETIGEAPRQYVNRLSDLLF
VLARVLNRADGGTDVLWKRDEHKPA
>Mature_184_residues
GNRLSKIATRTGDDGTTGLGDGSRTAKDSLRIAAIGDVDELNSHIGVLLTETLPDGVRTALTAIQHDLFDLGGELCIPGY
TMVTTAHVLRLDQWLADYNADLPRLAEFILPGGSRAAAQAHVCRTVARRAERSIVALGRAETIGEAPRQYVNRLSDLLFV
LARVLNRADGGTDVLWKRDEHKPA

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI16418349, Length=189, Percent_Identity=35.978835978836, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI115534154, Length=192, Percent_Identity=34.8958333333333, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- ProDom:   PD007457 [H]

Pfam domain/function: PF01923 Cob_adeno_trans [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19981; Mature: 19850

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRLSKIATRTGDDGTTGLGDGSRTAKDSLRIAAIGDVDELNSHIGVLLTETLPDGVRT
CCCHHHHHHHCCCCCCCCCCCCCCCCHHHCEEEEEECCHHHHHHHHHEEEHHHCCHHHHH
ALTAIQHDLFDLGGELCIPGYTMVTTAHVLRLDQWLADYNADLPRLAEFILPGGSRAAAQ
HHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
AHVCRTVARRAERSIVALGRAETIGEAPRQYVNRLSDLLFVLARVLNRADGGTDVLWKRD
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
EHKPA
CCCCC
>Mature Secondary Structure 
GNRLSKIATRTGDDGTTGLGDGSRTAKDSLRIAAIGDVDELNSHIGVLLTETLPDGVRT
CCHHHHHHHCCCCCCCCCCCCCCCCHHHCEEEEEECCHHHHHHHHHEEEHHHCCHHHHH
ALTAIQHDLFDLGGELCIPGYTMVTTAHVLRLDQWLADYNADLPRLAEFILPGGSRAAAQ
HHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHH
AHVCRTVARRAERSIVALGRAETIGEAPRQYVNRLSDLLFVLARVLNRADGGTDVLWKRD
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECC
EHKPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]