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The map label for this gene is pabB [H]

Identifier: 187929936

GI number: 187929936

Start: 2971536

End: 2973434

Strand: Reverse

Name: pabB [H]

Synonym: Rpic_2868

Alternate gene names: 187929936

Gene position: 2973434-2971536 (Counterclockwise)

Preceding gene: 187929937

Following gene: 187929926

Centisome position: 75.42

GC content: 67.3

Gene sequence:

>1899_bases
ATGCAGCCGCTCCAAGCGCCAGACGCCGGCGCGCCGTTCGCGCTGCTGGACGATGCCACCTCGGGCGACGCGCCGTGCTC
GCGCTGGTACGCCGGTTATGTCGGCGAGTTCTTCCGGCCGGCCGGCATGCTCGAGGGGCTGGACGATGATCTTCGTGCCG
CCTGGCGCGAGGGTTTGCATGCCCTGATCATTGCGCCGTATGAGTTTGGTGGGCCGCTGGTCGGTCTGCCGGCTTCCACG
GAAACGTCTTCTTCATTGCCTGGCCACGATGGCCGCCTGCGCGTGCTGCTGTTTCGCACGATGCAGGTGCTGTCGCCGGC
AGAGGTCGATACGTTGTTCGACGCGTGGCCCGAAGCGAGCGGGGCAGCGGGCCTGTTCGATTGTGCGGCCAGCGTCGATC
ACGCCACCTATACCGACGCCATCGCGCGCATCCACGACTGGATTGCGGCGGGCGATACCTACGAAGTCAACTACACGTAC
CGCCTGCGCATGACGGCGTTTGGCGCGCCAGCGGCGTTGTATCGGCGCCTGCGTGCGCGTCAGCCGGTGCCGTACGGCGC
CTTCATCGGGCTGCCGGAGGGCGCCGCGATTCTGTCGTGCTCGCCGGAGCTGTTCTTTTCGCATCGCGCCGGCCAGCTTG
TCGCGCGGCCGATGAAGGGCACCGCGCCAGCCTCCGGCGACGTCGAAGTCGACGAAGCCCGCGCCATCGCACTGGCCGCA
GACGAAAAGAACCGCGCCGAGAACTTGATGATCGTCGACCTCTTGCGCAACGATCTGGGCCGCCTCGCGCGAGCGGGGTC
AGTGCACGTGCCGGCGTTGTTCGAGGTGACGCCGTTCGGCAGCGTGCTCCAGATGACGTCAACCGTCGAGGCCGAGATTC
CGCCCGCCACCGGCCTTGCCGATTGCCTGCGAGCGTTGTTCCCGTGCGGCTCGATCACCGGCGCGCCCAAGCGGCGGACC
ATGGAGATCATCGAGGCGCTCGAGCCCGAGCCGCGTGGTCTGTACACCGGCGCCATCGGCTGGATCGATGCGCCTGCCGA
CGATCGAGCGATGGGCGACGCATGCTTCTCGGTGGCGATCCGCACGCTGGTCCTTGGCGCGCCCGGCACCGATGGTCTGC
GTCGCGGCGAACTAGGCATTGGCTCCGGCATCGTGCACGACAGCATCGCCGATGAGGAGTACGCGGAGTGCCAACTGAAA
GCGCGCTTCGTGACGGCGCTTGACCCGGGGTTATCGCTGTTTGAGACGATGCGCGCGACGCGCGAGGGCGTGGCGCTGCT
GGATTGGCATCTGGCGCGGCTGGAGCGTTCAGCGGCAGCCTTTGGTTTCCCGTTCGATCGGACTGCACTGACGAATGATG
TGGCGCGTGCGTGCGCAACGCTGGAAGGCGAGGGCGCCTATCGCATGCGCCTGTTGCTTACCCCGGACGGTGGAGCAAAC
GTATCGGCCGTGCCGCTGTCACCGCTGCATGCCAGCTGGGATGCGCCGGTCCGCCTGCTGGTCGCATCGCAACCGCGTGA
GGTCACGCACAGTCTGCCGACGCACAAGACCACGTTGCGCGAAGGCTACGATGCAGCCTGGCAGGCCGCCGAGCGCGCAG
GTGCATTCGATGCCGTGTTCTTCAACGCCGATGGCACATTGGCCGAAGGGGGGCGCAGCACGTTGCTGGTCAAGCTCGAT
GGCGCGTGGTGCACTCCGCCGCTGTCCGCAGGCGTCTTGCCGGGGGTGATGCGTGCCGTGCTGTTGAACGACGCTTTGCC
ATGGCTTGGCGGGCCGCTGCAAGAGCGTTCGCTCACCCGCGCCGATGTTGCCCGCGCAGAGGCCATCGCCGTATGCAACG
CCTTACGCGGTGTGGTGCCCGCGCATTTCGAGCCGGCCTTGACCGTTGACGTGCTCTAG

Upstream 100 bases:

>100_bases
GTCGTACCGATGTACGGCTGCGCTTCTCGTACCAACCTCGGGCCGCTCGCTACGCTTTTCGAGGCTTCTTGAACACCATC
TTTTCGATCAGGACTTCGTC

Downstream 100 bases:

>100_bases
CTTCCAGCGCGCCACGCCGGGCAGGTTGATCAGTTCGCGGTCGTGGCAGACCATCAGCAGTGTGCGGCCCTCTGCTGCCA
GTTCTCCCACAAGCGCAATG

Product: para-aminobenzoate synthase subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 632; Mature: 632

Protein sequence:

>632_residues
MQPLQAPDAGAPFALLDDATSGDAPCSRWYAGYVGEFFRPAGMLEGLDDDLRAAWREGLHALIIAPYEFGGPLVGLPAST
ETSSSLPGHDGRLRVLLFRTMQVLSPAEVDTLFDAWPEASGAAGLFDCAASVDHATYTDAIARIHDWIAAGDTYEVNYTY
RLRMTAFGAPAALYRRLRARQPVPYGAFIGLPEGAAILSCSPELFFSHRAGQLVARPMKGTAPASGDVEVDEARAIALAA
DEKNRAENLMIVDLLRNDLGRLARAGSVHVPALFEVTPFGSVLQMTSTVEAEIPPATGLADCLRALFPCGSITGAPKRRT
MEIIEALEPEPRGLYTGAIGWIDAPADDRAMGDACFSVAIRTLVLGAPGTDGLRRGELGIGSGIVHDSIADEEYAECQLK
ARFVTALDPGLSLFETMRATREGVALLDWHLARLERSAAAFGFPFDRTALTNDVARACATLEGEGAYRMRLLLTPDGGAN
VSAVPLSPLHASWDAPVRLLVASQPREVTHSLPTHKTTLREGYDAAWQAAERAGAFDAVFFNADGTLAEGGRSTLLVKLD
GAWCTPPLSAGVLPGVMRAVLLNDALPWLGGPLQERSLTRADVARAEAIAVCNALRGVVPAHFEPALTVDVL

Sequences:

>Translated_632_residues
MQPLQAPDAGAPFALLDDATSGDAPCSRWYAGYVGEFFRPAGMLEGLDDDLRAAWREGLHALIIAPYEFGGPLVGLPAST
ETSSSLPGHDGRLRVLLFRTMQVLSPAEVDTLFDAWPEASGAAGLFDCAASVDHATYTDAIARIHDWIAAGDTYEVNYTY
RLRMTAFGAPAALYRRLRARQPVPYGAFIGLPEGAAILSCSPELFFSHRAGQLVARPMKGTAPASGDVEVDEARAIALAA
DEKNRAENLMIVDLLRNDLGRLARAGSVHVPALFEVTPFGSVLQMTSTVEAEIPPATGLADCLRALFPCGSITGAPKRRT
MEIIEALEPEPRGLYTGAIGWIDAPADDRAMGDACFSVAIRTLVLGAPGTDGLRRGELGIGSGIVHDSIADEEYAECQLK
ARFVTALDPGLSLFETMRATREGVALLDWHLARLERSAAAFGFPFDRTALTNDVARACATLEGEGAYRMRLLLTPDGGAN
VSAVPLSPLHASWDAPVRLLVASQPREVTHSLPTHKTTLREGYDAAWQAAERAGAFDAVFFNADGTLAEGGRSTLLVKLD
GAWCTPPLSAGVLPGVMRAVLLNDALPWLGGPLQERSLTRADVARAEAIAVCNALRGVVPAHFEPALTVDVL
>Mature_632_residues
MQPLQAPDAGAPFALLDDATSGDAPCSRWYAGYVGEFFRPAGMLEGLDDDLRAAWREGLHALIIAPYEFGGPLVGLPAST
ETSSSLPGHDGRLRVLLFRTMQVLSPAEVDTLFDAWPEASGAAGLFDCAASVDHATYTDAIARIHDWIAAGDTYEVNYTY
RLRMTAFGAPAALYRRLRARQPVPYGAFIGLPEGAAILSCSPELFFSHRAGQLVARPMKGTAPASGDVEVDEARAIALAA
DEKNRAENLMIVDLLRNDLGRLARAGSVHVPALFEVTPFGSVLQMTSTVEAEIPPATGLADCLRALFPCGSITGAPKRRT
MEIIEALEPEPRGLYTGAIGWIDAPADDRAMGDACFSVAIRTLVLGAPGTDGLRRGELGIGSGIVHDSIADEEYAECQLK
ARFVTALDPGLSLFETMRATREGVALLDWHLARLERSAAAFGFPFDRTALTNDVARACATLEGEGAYRMRLLLTPDGGAN
VSAVPLSPLHASWDAPVRLLVASQPREVTHSLPTHKTTLREGYDAAWQAAERAGAFDAVFFNADGTLAEGGRSTLLVKLD
GAWCTPPLSAGVLPGVMRAVLLNDALPWLGGPLQERSLTRADVARAEAIAVCNALRGVVPAHFEPALTVDVL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=375, Percent_Identity=36.8, Blast_Score=188, Evalue=1e-48,
Organism=Escherichia coli, GI1787518, Length=285, Percent_Identity=29.1228070175439, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786809, Length=285, Percent_Identity=23.859649122807, Blast_Score=72, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6320935, Length=273, Percent_Identity=33.6996336996337, Blast_Score=132, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6324361, Length=309, Percent_Identity=28.8025889967638, Blast_Score=100, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 67260; Mature: 67260

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLQAPDAGAPFALLDDATSGDAPCSRWYAGYVGEFFRPAGMLEGLDDDLRAAWREGLH
CCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCE
ALIIAPYEFGGPLVGLPASTETSSSLPGHDGRLRVLLFRTMQVLSPAEVDTLFDAWPEAS
EEEEEECCCCCCEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHCCCCCC
GAAGLFDCAASVDHATYTDAIARIHDWIAAGDTYEVNYTYRLRMTAFGAPAALYRRLRAR
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCHHHHHHHHHHC
QPVPYGAFIGLPEGAAILSCSPELFFSHRAGQLVARPMKGTAPASGDVEVDEARAIALAA
CCCCCCEEEECCCCCEEEECCHHHHHCCCCCHHHCCCCCCCCCCCCCEEECCCEEEEEEE
DEKNRAENLMIVDLLRNDLGRLARAGSVHVPALFEVTPFGSVLQMTSTVEAEIPPATGLA
CCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHH
DCLRALFPCGSITGAPKRRTMEIIEALEPEPRGLYTGAIGWIDAPADDRAMGDACFSVAI
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHH
RTLVLGAPGTDGLRRGELGIGSGIVHDSIADEEYAECQLKARFVTALDPGLSLFETMRAT
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCHHHHHHHHHH
REGVALLDWHLARLERSAAAFGFPFDRTALTNDVARACATLEGEGAYRMRLLLTPDGGAN
HCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
VSAVPLSPLHASWDAPVRLLVASQPREVTHSLPTHKTTLREGYDAAWQAAERAGAFDAVF
EEEEECCCCCCCCCCCEEEEEECCCHHHHHCCCCCHHHHHHCHHHHHHHHHHCCCEEEEE
FNADGTLAEGGRSTLLVKLDGAWCTPPLSAGVLPGVMRAVLLNDALPWLGGPLQERSLTR
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCHHHHHHHH
ADVARAEAIAVCNALRGVVPAHFEPALTVDVL
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC
>Mature Secondary Structure
MQPLQAPDAGAPFALLDDATSGDAPCSRWYAGYVGEFFRPAGMLEGLDDDLRAAWREGLH
CCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHCCCE
ALIIAPYEFGGPLVGLPASTETSSSLPGHDGRLRVLLFRTMQVLSPAEVDTLFDAWPEAS
EEEEEECCCCCCEEECCCCCCCCCCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHCCCCCC
GAAGLFDCAASVDHATYTDAIARIHDWIAAGDTYEVNYTYRLRMTAFGAPAALYRRLRAR
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCHHHHHHHHHHC
QPVPYGAFIGLPEGAAILSCSPELFFSHRAGQLVARPMKGTAPASGDVEVDEARAIALAA
CCCCCCEEEECCCCCEEEECCHHHHHCCCCCHHHCCCCCCCCCCCCCEEECCCEEEEEEE
DEKNRAENLMIVDLLRNDLGRLARAGSVHVPALFEVTPFGSVLQMTSTVEAEIPPATGLA
CCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCHH
DCLRALFPCGSITGAPKRRTMEIIEALEPEPRGLYTGAIGWIDAPADDRAMGDACFSVAI
HHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHH
RTLVLGAPGTDGLRRGELGIGSGIVHDSIADEEYAECQLKARFVTALDPGLSLFETMRAT
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEECCCCCHHHHHHHHHH
REGVALLDWHLARLERSAAAFGFPFDRTALTNDVARACATLEGEGAYRMRLLLTPDGGAN
HCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCC
VSAVPLSPLHASWDAPVRLLVASQPREVTHSLPTHKTTLREGYDAAWQAAERAGAFDAVF
EEEEECCCCCCCCCCCEEEEEECCCHHHHHCCCCCHHHHHHCHHHHHHHHHHCCCEEEEE
FNADGTLAEGGRSTLLVKLDGAWCTPPLSAGVLPGVMRAVLLNDALPWLGGPLQERSLTR
ECCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHCCCCHHHHHHHH
ADVARAEAIAVCNALRGVVPAHFEPALTVDVL
HHHHHHHHHHHHHHHHCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]