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The map label for this gene is arcB

Identifier: 187929898

GI number: 187929898

Start: 2938618

End: 2939544

Strand: Reverse

Name: arcB

Synonym: Rpic_2830

Alternate gene names: 187929898

Gene position: 2939544-2938618 (Counterclockwise)

Preceding gene: 187929900

Following gene: 187929894

Centisome position: 74.56

GC content: 61.06

Gene sequence:

>927_bases
ATGAACCCACCAAGCTCGATCAAGCACTACCTGCAGTTCAAGGACTTTTCTCTGGAAGAGTACGAATACCTGCTGGACCG
TTCCGCGATCCTCAAGGCCAAGTTCAAGAACTACGAGACGTGGCACCCGCTGCACGACCGCACGCTGGCCATGATCTTCG
AGAAGAATTCCACGCGTACGCGCCTGTCGTTCGAAGCCGGCATTCACCAGCTCGGCGGTCACGCAGTCTTCCTGAATACG
CGCGATTCCCAGCTTGGGCGCGGTGAGCCGATCGAAGACGCGGCGCAGGTCATCTCCCGCATGACCGACATCATCATGAT
CCGCACCTTCGGGCAGGAGATCATCGAGCGCTTTGCTGCGCATTCGCGCGTGCCGGTCATCAACGGGCTGACCAACGAAT
ACCACCCGTGCCAGGTGCTGGCCGACATCTTTACCTTCATCGAGCAGCGCGGCCCCATCAAGGGCAAGACCGTCACCTGG
GTGGGCGATGCCAACAACATGGCCTACACGTGGGTCCAGGCGGCGGAGATTCTCGGCTTCCGCTTCCATTTTTCTGCGCC
GAAGGGCTATCAGCTGGATCCGGCCATGGTGGCCGATTCCGCCTTGCCGTTCGTGCATGTGTTCGAAAACCCGCTCGAAG
CCTGCGACGGCGCGCATCTGGTGACCACGGACGTGTGGACCAGCATGGGCTACGAAGCTGAAAACGAAGCGCGCAAGAAG
GCCTTTGGCGACTGGATGGTCACCGAGGCGATGATGCAGCGCGCGCAACCCGATGCGCTGTTCATGCACTGCCTGCCCGC
TCACCGCGGCGAGGAAGTCGAAGCGGCCGTCATCGACGGCAAGCAGAGCGTCGTGTGGGACGAGGCGGAAAACCGCCTGC
ACGTGCAGAAGGCGCTGATGGAATATCTGCTCTGCGGTCGCTACTGA

Upstream 100 bases:

>100_bases
ATCCCGTATGATGGCCTGAATCTTCAACAGGCAAGGCGGCTAGGGCGACGTGCCACGGGATGTTCCCGGTGCGTCAACTG
CAGGCCGCCTTCGTTGTTTT

Downstream 100 bases:

>100_bases
GCGCGCAGTCGCCCAGATCTGCAGGCATAAAAAAGGCCGCTCCGATTGACGTCGGAGCGGCCTTTTTGCCTTGAAGCGGC
AGGCAGTTACTTCTTGCCGC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNPPSSIKHYLQFKDFSLEEYEYLLDRSAILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNT
RDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFAAHSRVPVINGLTNEYHPCQVLADIFTFIEQRGPIKGKTVTW
VGDANNMAYTWVQAAEILGFRFHFSAPKGYQLDPAMVADSALPFVHVFENPLEACDGAHLVTTDVWTSMGYEAENEARKK
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALMEYLLCGRY

Sequences:

>Translated_308_residues
MNPPSSIKHYLQFKDFSLEEYEYLLDRSAILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNT
RDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFAAHSRVPVINGLTNEYHPCQVLADIFTFIEQRGPIKGKTVTW
VGDANNMAYTWVQAAEILGFRFHFSAPKGYQLDPAMVADSALPFVHVFENPLEACDGAHLVTTDVWTSMGYEAENEARKK
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALMEYLLCGRY
>Mature_308_residues
MNPPSSIKHYLQFKDFSLEEYEYLLDRSAILKAKFKNYETWHPLHDRTLAMIFEKNSTRTRLSFEAGIHQLGGHAVFLNT
RDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFAAHSRVPVINGLTNEYHPCQVLADIFTFIEQRGPIKGKTVTW
VGDANNMAYTWVQAAEILGFRFHFSAPKGYQLDPAMVADSALPFVHVFENPLEACDGAHLVTTDVWTSMGYEAENEARKK
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALMEYLLCGRY

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family

Homologues:

Organism=Homo sapiens, GI38788445, Length=305, Percent_Identity=39.0163934426229, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI18105007, Length=311, Percent_Identity=28.2958199356913, Blast_Score=112, Evalue=4e-25,
Organism=Escherichia coli, GI1790703, Length=325, Percent_Identity=37.8461538461538, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1786469, Length=325, Percent_Identity=37.8461538461538, Blast_Score=193, Evalue=1e-50,
Organism=Escherichia coli, GI2367364, Length=207, Percent_Identity=34.7826086956522, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193204318, Length=296, Percent_Identity=27.3648648648649, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322373, Length=326, Percent_Identity=34.0490797546012, Blast_Score=183, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6322331, Length=163, Percent_Identity=31.2883435582822, Blast_Score=82, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24642586, Length=314, Percent_Identity=27.3885350318471, Blast_Score=111, Evalue=8e-25,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): OTC_RALPJ (B2UBA4)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001900385.1
- ProteinModelPortal:   B2UBA4
- SMR:   B2UBA4
- GeneID:   6287502
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_2830
- HOGENOM:   HBG579429
- OMA:   KHETLLE
- ProtClustDB:   PRK00779
- HAMAP:   MF_01109
- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292
- PRINTS:   PR00100
- PRINTS:   PR00102
- TIGRFAMs:   TIGR00658

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N; SSF53671 Asp/Orn_carbamoyltranf

EC number: =2.1.3.3

Molecular weight: Translated: 35116; Mature: 35116

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: BINDING 108-108 BINDING 135-135

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPSSIKHYLQFKDFSLEEYEYLLDRSAILKAKFKNYETWHPLHDRTLAMIFEKNSTRT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCE
RLSFEAGIHQLGGHAVFLNTRDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFAA
EEEHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSRVPVINGLTNEYHPCQVLADIFTFIEQRGPIKGKTVTWVGDANNMAYTWVQAAEILGF
CCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHEE
RFHFSAPKGYQLDPAMVADSALPFVHVFENPLEACDGAHLVTTDVWTSMGYEAENEARKK
EEEECCCCCCCCCHHHHHHCCCCHHHHHHCHHHHCCCCEEEEHHHHHHCCCCCHHHHHHH
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALM
HHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
EYLLCGRY
HHHHHCCC
>Mature Secondary Structure
MNPPSSIKHYLQFKDFSLEEYEYLLDRSAILKAKFKNYETWHPLHDRTLAMIFEKNSTRT
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCE
RLSFEAGIHQLGGHAVFLNTRDSQLGRGEPIEDAAQVISRMTDIIMIRTFGQEIIERFAA
EEEHHHHHHHHCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSRVPVINGLTNEYHPCQVLADIFTFIEQRGPIKGKTVTWVGDANNMAYTWVQAAEILGF
CCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHEE
RFHFSAPKGYQLDPAMVADSALPFVHVFENPLEACDGAHLVTTDVWTSMGYEAENEARKK
EEEECCCCCCCCCHHHHHHCCCCHHHHHHCHHHHCCCCEEEEHHHHHHCCCCCHHHHHHH
AFGDWMVTEAMMQRAQPDALFMHCLPAHRGEEVEAAVIDGKQSVVWDEAENRLHVQKALM
HHHHHHHHHHHHHHCCCCCEEHHHHCCCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHH
EYLLCGRY
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA