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The map label for this gene is ftsK2 [H]

Identifier: 187929629

GI number: 187929629

Start: 2661580

End: 2663925

Strand: Reverse

Name: ftsK2 [H]

Synonym: Rpic_2556

Alternate gene names: 187929629

Gene position: 2663925-2661580 (Counterclockwise)

Preceding gene: 187929633

Following gene: 187929628

Centisome position: 67.57

GC content: 64.75

Gene sequence:

>2346_bases
ATGGCTCGAGCTTCCACCACTCCGACAACCCGCACCGATCCGTCCGCACTGCCGTCCCGCATTGGGCGGCTGCTGGGGGA
GGTCCGCTGGTTCCTGTTGCTGGCGGTGACCATCGCCTTCCTGATCATTCTCCTGTCATACAACCGCGCCGATCCCGGTT
TCACCCACGCCAGCCAGGTCGACGAAATCCGCAACCTGGGCGGCCGCGTGGGCGCGTGGCTGGCCGATCTGCTGCTGTTT
GTCTTTGGCGCGTCCGCCTACTGGTGGGCGGTGCTGCTCGTGCGCAAGGTCTGGCGCGGCTGGCGCGAGCTGATGTCGGA
CGAACGCCTGCCGCGCACCTCCATGCCGCGCGTTGATGCCAGTGTCACGTGGATCGGCTTTGCGCTCATCCTGGCTTCCA
GCATGGGTTTGGAAGCCATCCGCATGTACTCGCTGCACATGAAGCTGCCGCGTGCGCCGGGCGGCGTGCTGGGCGATGTG
ATCGGCGGGGCGATGCAGCATTCGCTGGGCTTTACCGGCGGCACGCTGGCGCTGCTGTTTACGTTCCTGGTCGGGCTGTC
GCTGTTCTTCCATTTCTCGTGGCTGAACCTGGCCGAGCAGATCGGCGCCGGCGTCGAGATGCTGTTCGTCGGCTTCAAGA
CGCGCCGCGAGAGCAAACAGGACCGCGCCATCGGCGAGGCGGCCAAGGTCGAGCGCGAGGAAGTGGTCGAAACCCGCCGC
GTGCGCATTGAAGAATCGCCGCCGGTGCAGATCGTGCGCCCGACCGCCGTGGTCAAGAGCGAGCGCGTGGAGCGCGAGAA
GCAGCAGCCGCTGTTTGTCGACATGCACGATTCCGACCTGCCCCCGCTCGCGCTGCTCGATCCGATTCCGCCGGTTGTGG
AAACCGTGAGCGCCGAGACGCTGGAATTCACCTCGCGCCTGATCGAGAAGAAGCTCAAGGATTTCGGCGTGGAAGTGCAG
GTGGTGGCGGCCTATCCGGGCCCGGTCATCACGCGCTACGAAATCGAGCCCGCCACGGGCGTCAAGGGCAGCCAGATCGT
CAACCTGGCGAAGGACCTGGCGCGTTCGCTGTCGTTGGTGTCGATCCGCGTGGTGGAGACAATTCCAGGCAAGAACTGCA
TGGGCCTGGAGCTGCCGAACCCGAAGCGCCAAGCGGTGCGCCTGTCGGAGATTCTCGGCTCGCAGGTCTACAACGAGAGC
GCATCGCAGCTCACGCTGGCGCTGGGCAAGGATATTGCCGGCAAGCCGGTCGTGGCCGACCTGGCCAAGATGCCGCACTG
CATGGTGGCTGGTACCACGGGCTCAGGTAAGTCGGTCGGGATCAACGCGATGATCCTGTCGCTGCTGTACAAGGCGAAGG
CCGACGCGGTGCGCCTGATTCTGATCGACCCGAAGATGCTGGAACTGAGCATCTACGAAGGCATTCCCCATCTGCTGTGC
CCAGTCGTGACGGACATGCGCCAAGCCGGTCACGCGCTCAACTGGGCTGTGGGCGAGATGGAGCGCCGCTACAAGCTCAT
GAGCAAGATGGGCGTGCGAAACCTGGCCGGCTTCAACAAGAAGATCGAAGAAGCCGCTGCGCGCGAAGAAAAGATTCCCA
ACCCGTTCAGCCTGACGCCTGACGCGCCGGAGCCGCTCGACAAGCTGCCGATGATTGTCATCGTGATCGACGAACTGGCC
GACCTGATGATGGTGGTCGGCAAGAAGGTCGAAGAGCTGATCGCGCGGATTGCGCAGAAGGCGCGTGCCGCCGGTATCCA
CCTCGTGCTGGCAACGCAGCGTCCGTCGGTGGACGTGATTACGGGCCTGATCAAGGCCAACGTGCCGACGCGGATCGCGT
TCCAGGTCAGCAGCAAGATCGACTCGCGCACCATCCTTGACCAGCAGGGCGCCGAAGCGCTGCTGGGCATGGGCGACATG
CTGTATCTCGCGCCGGGCACCGGCTTGCCAGTGCGCGTGCACGGCGCGTTCGTGTCGGACGAGGAAGTCCACCGCATCGT
CGATAACCTGAAGGCGCAAGGCGAGCCGAACTACATCGAAGGCATTCTCGAAGGCGGTGTGGCCGATGGCGAGGGCGGTG
GCGATGGCTCTGGTGGCGGTGCTGGCCTTGTGGGTGCGGGCGGCGGCGAGGCCGATCCACTGTACGACCAGGCTGTCGAT
GTGGTGCTCAAGAATCGCCGCGCGTCGATCTCGCTGGTGCAGCGTCACCTGCGCATCGGCTACAACCGCGCCGCACGCCT
GCTCGAAGACATGGAAAAGGCGGGGCTCGTGTCCGCCATGTCGGGCAACGGCAACCGTGAAATCCTGGCGCCCAACCGCA
ACGGCAACGTCGTCGAAGAGGAATGA

Upstream 100 bases:

>100_bases
ATTCCAATGGCGGTGATAGGGCCGCGTTACAATCGTTGGCATCGTATTTGTGCTGTCCCAAGCCGCGCGGCCTCGTCCAA
GCGGCGCACCCGTCTCCCGC

Downstream 100 bases:

>100_bases
CGCTGCCCGCGCGCTGCGCGCATTTGCCGTTACATCGCGTTACCGCACGGGCGGAATGTTCCGTCGCTGCCGGCCACTAA
CAACAAGATCAACTGAAACC

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:

>781_residues
MARASTTPTTRTDPSALPSRIGRLLGEVRWFLLLAVTIAFLIILLSYNRADPGFTHASQVDEIRNLGGRVGAWLADLLLF
VFGASAYWWAVLLVRKVWRGWRELMSDERLPRTSMPRVDASVTWIGFALILASSMGLEAIRMYSLHMKLPRAPGGVLGDV
IGGAMQHSLGFTGGTLALLFTFLVGLSLFFHFSWLNLAEQIGAGVEMLFVGFKTRRESKQDRAIGEAAKVEREEVVETRR
VRIEESPPVQIVRPTAVVKSERVEREKQQPLFVDMHDSDLPPLALLDPIPPVVETVSAETLEFTSRLIEKKLKDFGVEVQ
VVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNCMGLELPNPKRQAVRLSEILGSQVYNES
ASQLTLALGKDIAGKPVVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKADAVRLILIDPKMLELSIYEGIPHLLC
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIPNPFSLTPDAPEPLDKLPMIVIVIDELA
DLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDM
LYLAPGTGLPVRVHGAFVSDEEVHRIVDNLKAQGEPNYIEGILEGGVADGEGGGDGSGGGAGLVGAGGGEADPLYDQAVD
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEEE

Sequences:

>Translated_781_residues
MARASTTPTTRTDPSALPSRIGRLLGEVRWFLLLAVTIAFLIILLSYNRADPGFTHASQVDEIRNLGGRVGAWLADLLLF
VFGASAYWWAVLLVRKVWRGWRELMSDERLPRTSMPRVDASVTWIGFALILASSMGLEAIRMYSLHMKLPRAPGGVLGDV
IGGAMQHSLGFTGGTLALLFTFLVGLSLFFHFSWLNLAEQIGAGVEMLFVGFKTRRESKQDRAIGEAAKVEREEVVETRR
VRIEESPPVQIVRPTAVVKSERVEREKQQPLFVDMHDSDLPPLALLDPIPPVVETVSAETLEFTSRLIEKKLKDFGVEVQ
VVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNCMGLELPNPKRQAVRLSEILGSQVYNES
ASQLTLALGKDIAGKPVVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKADAVRLILIDPKMLELSIYEGIPHLLC
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIPNPFSLTPDAPEPLDKLPMIVIVIDELA
DLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDM
LYLAPGTGLPVRVHGAFVSDEEVHRIVDNLKAQGEPNYIEGILEGGVADGEGGGDGSGGGAGLVGAGGGEADPLYDQAVD
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEEE
>Mature_780_residues
ARASTTPTTRTDPSALPSRIGRLLGEVRWFLLLAVTIAFLIILLSYNRADPGFTHASQVDEIRNLGGRVGAWLADLLLFV
FGASAYWWAVLLVRKVWRGWRELMSDERLPRTSMPRVDASVTWIGFALILASSMGLEAIRMYSLHMKLPRAPGGVLGDVI
GGAMQHSLGFTGGTLALLFTFLVGLSLFFHFSWLNLAEQIGAGVEMLFVGFKTRRESKQDRAIGEAAKVEREEVVETRRV
RIEESPPVQIVRPTAVVKSERVEREKQQPLFVDMHDSDLPPLALLDPIPPVVETVSAETLEFTSRLIEKKLKDFGVEVQV
VAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLVSIRVVETIPGKNCMGLELPNPKRQAVRLSEILGSQVYNESA
SQLTLALGKDIAGKPVVADLAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKADAVRLILIDPKMLELSIYEGIPHLLCP
VVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIPNPFSLTPDAPEPLDKLPMIVIVIDELAD
LMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVITGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDML
YLAPGTGLPVRVHGAFVSDEEVHRIVDNLKAQGEPNYIEGILEGGVADGEGGGDGSGGGAGLVGAGGGEADPLYDQAVDV
VLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEEE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=496, Percent_Identity=64.3145161290323, Blast_Score=609, Evalue=1e-175,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 84747; Mature: 84616

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARASTTPTTRTDPSALPSRIGRLLGEVRWFLLLAVTIAFLIILLSYNRADPGFTHASQV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DEIRNLGGRVGAWLADLLLFVFGASAYWWAVLLVRKVWRGWRELMSDERLPRTSMPRVDA
HHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SVTWIGFALILASSMGLEAIRMYSLHMKLPRAPGGVLGDVIGGAMQHSLGFTGGTLALLF
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
TFLVGLSLFFHFSWLNLAEQIGAGVEMLFVGFKTRRESKQDRAIGEAAKVEREEVVETRR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VRIEESPPVQIVRPTAVVKSERVEREKQQPLFVDMHDSDLPPLALLDPIPPVVETVSAET
HEECCCCCCEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHH
LEFTSRLIEKKLKDFGVEVQVVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLV
HHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SIRVVETIPGKNCMGLELPNPKRQAVRLSEILGSQVYNESASQLTLALGKDIAGKPVVAD
EEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHEEHHHCCCCCCCCHHHH
LAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKADAVRLILIDPKMLELSIYEGIPHLLC
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHCCHHHHH
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIPNPFSLTP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DAPEPLDKLPMIVIVIDELADLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVI
CCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHH
TGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSD
HHHHHCCCCCEEEEEECCCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEECCCCH
EEVHRIVDNLKAQGEPNYIEGILEGGVADGEGGGDGSGGGAGLVGAGGGEADPLYDQAVD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHH
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEE
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEECCCCCCEEECCCCCCCCCCC
E
C
>Mature Secondary Structure 
ARASTTPTTRTDPSALPSRIGRLLGEVRWFLLLAVTIAFLIILLSYNRADPGFTHASQV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
DEIRNLGGRVGAWLADLLLFVFGASAYWWAVLLVRKVWRGWRELMSDERLPRTSMPRVDA
HHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
SVTWIGFALILASSMGLEAIRMYSLHMKLPRAPGGVLGDVIGGAMQHSLGFTGGTLALLF
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHH
TFLVGLSLFFHFSWLNLAEQIGAGVEMLFVGFKTRRESKQDRAIGEAAKVEREEVVETRR
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VRIEESPPVQIVRPTAVVKSERVEREKQQPLFVDMHDSDLPPLALLDPIPPVVETVSAET
HEECCCCCCEEECCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHH
LEFTSRLIEKKLKDFGVEVQVVAAYPGPVITRYEIEPATGVKGSQIVNLAKDLARSLSLV
HHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
SIRVVETIPGKNCMGLELPNPKRQAVRLSEILGSQVYNESASQLTLALGKDIAGKPVVAD
EEEEEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHEEHHHCCCCCCCCHHHH
LAKMPHCMVAGTTGSGKSVGINAMILSLLYKAKADAVRLILIDPKMLELSIYEGIPHLLC
HHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHCCHHHHH
PVVTDMRQAGHALNWAVGEMERRYKLMSKMGVRNLAGFNKKIEEAAAREEKIPNPFSLTP
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
DAPEPLDKLPMIVIVIDELADLMMVVGKKVEELIARIAQKARAAGIHLVLATQRPSVDVI
CCCCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHH
TGLIKANVPTRIAFQVSSKIDSRTILDQQGAEALLGMGDMLYLAPGTGLPVRVHGAFVSD
HHHHHCCCCCEEEEEECCCCCHHHHHHHCCHHHHHCCCCEEEECCCCCCCEEEEECCCCH
EEVHRIVDNLKAQGEPNYIEGILEGGVADGEGGGDGSGGGAGLVGAGGGEADPLYDQAVD
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHH
VVLKNRRASISLVQRHLRIGYNRAARLLEDMEKAGLVSAMSGNGNREILAPNRNGNVVEE
HHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEEEECCCCCCEEECCCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]