Click here to switch to the map view.

The map label for this gene is lolA

Identifier: 187929628

GI number: 187929628

Start: 2660823

End: 2661470

Strand: Reverse

Name: lolA

Synonym: Rpic_2555

Alternate gene names: 187929628

Gene position: 2661470-2660823 (Counterclockwise)

Preceding gene: 187929629

Following gene: 187929627

Centisome position: 67.51

GC content: 62.35

Gene sequence:

>648_bases
ATGTTTGTGTTGAACGCGCGTCACCTGATGGCCGCCGGGCTGGTCTCTCTGGCGGCATGGTCTGCCGGCGCCTATGCAGG
TGCGGTCGAACAGCTCAACGCCTTTGTGAGCAACGTCAGCACTGCGCGCGGCGAGTTCGTGCAACGGCAGGTGAAGGGCG
GCACCAACGGCAGCCCGCTGCGCGTGGCCGGGACGTCCAACGGCGATTTTGTCTTCTCGCGCCCGGGCCGCTTCGTCTGG
CGCTATGTGAAGCCGTACGAACAGCAGCTCTCGGCCGACGGCCAGATGCTGTACATCTTCGACAAGGACCTGAACCAGAT
CACGGAGCGCAAGCTTGATGCGTCGCTGGGCTCCAGCCCCGCTGCCATCCTGTTTGGCAGCAATGATCTGGCCAAAAACT
TCACGCTTAAGGAAGGCGGCACCAAGGACGGCATCGACTGGGTCGAACTCACCCCCAAGGCAAAGGACACCCAGTTCCAG
CGCATCGCCATCGGTTTTCGCAGCGGCGAGCTGCAGGGGATGGAGCTGCGCGACGCCTTCGGGAACACCACCTTGCTGAC
GTTCTCGAACATCCAGAAGAATCCGCAACTGCCGGCCAACGTGTTCCGCTTTACGCCGCCCAAAGGGGCCGACGTCATCA
AGCAATGA

Upstream 100 bases:

>100_bases
CGCGCTGCGCGCATTTGCCGTTACATCGCGTTACCGCACGGGCGGAATGTTCCGTCGCTGCCGGCCACTAACAACAAGAT
CAACTGAAACCGGGATTCCT

Downstream 100 bases:

>100_bases
CGCGTGCAGGCCGGTTTTCGACCAGGAGACCGACCATGCCTTTGCCGTTCACCACGTCGCTGCACCGAGCAGCCGCTGTT
GCCGTCGCTGCGTCAGCGGC

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MFVLNARHLMAAGLVSLAAWSAGAYAGAVEQLNAFVSNVSTARGEFVQRQVKGGTNGSPLRVAGTSNGDFVFSRPGRFVW
RYVKPYEQQLSADGQMLYIFDKDLNQITERKLDASLGSSPAAILFGSNDLAKNFTLKEGGTKDGIDWVELTPKAKDTQFQ
RIAIGFRSGELQGMELRDAFGNTTLLTFSNIQKNPQLPANVFRFTPPKGADVIKQ

Sequences:

>Translated_215_residues
MFVLNARHLMAAGLVSLAAWSAGAYAGAVEQLNAFVSNVSTARGEFVQRQVKGGTNGSPLRVAGTSNGDFVFSRPGRFVW
RYVKPYEQQLSADGQMLYIFDKDLNQITERKLDASLGSSPAAILFGSNDLAKNFTLKEGGTKDGIDWVELTPKAKDTQFQ
RIAIGFRSGELQGMELRDAFGNTTLLTFSNIQKNPQLPANVFRFTPPKGADVIKQ
>Mature_215_residues
MFVLNARHLMAAGLVSLAAWSAGAYAGAVEQLNAFVSNVSTARGEFVQRQVKGGTNGSPLRVAGTSNGDFVFSRPGRFVW
RYVKPYEQQLSADGQMLYIFDKDLNQITERKLDASLGSSPAAILFGSNDLAKNFTLKEGGTKDGIDWVELTPKAKDTQFQ
RIAIGFRSGELQGMELRDAFGNTTLLTFSNIQKNPQLPANVFRFTPPKGADVIKQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

None

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_RALPJ (B2U9Y9)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001900115.1
- ProteinModelPortal:   B2U9Y9
- SMR:   B2U9Y9
- GeneID:   6289387
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_2555
- HOGENOM:   HBG688940
- OMA:   MELRDAF
- ProtClustDB:   PRK00031
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23470; Mature: 23470

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLNARHLMAAGLVSLAAWSAGAYAGAVEQLNAFVSNVSTARGEFVQRQVKGGTNGSPL
CEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
RVAGTSNGDFVFSRPGRFVWRYVKPYEQQLSADGQMLYIFDKDLNQITERKLDASLGSSP
EEEECCCCCEEEECCCCEEHHHHCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCC
AAILFGSNDLAKNFTLKEGGTKDGIDWVELTPKAKDTQFQRIAIGFRSGELQGMELRDAF
EEEEECCCCHHCCEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCCEEHHHHC
GNTTLLTFSNIQKNPQLPANVFRFTPPKGADVIKQ
CCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHCC
>Mature Secondary Structure
MFVLNARHLMAAGLVSLAAWSAGAYAGAVEQLNAFVSNVSTARGEFVQRQVKGGTNGSPL
CEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
RVAGTSNGDFVFSRPGRFVWRYVKPYEQQLSADGQMLYIFDKDLNQITERKLDASLGSSP
EEEECCCCCEEEECCCCEEHHHHCHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHCCCCC
AAILFGSNDLAKNFTLKEGGTKDGIDWVELTPKAKDTQFQRIAIGFRSGELQGMELRDAF
EEEEECCCCHHCCEEECCCCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCCEEHHHHC
GNTTLLTFSNIQKNPQLPANVFRFTPPKGADVIKQ
CCEEEEEECCCCCCCCCCCCEEEECCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA