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The map label for this gene is prsA [H]

Identifier: 187929591

GI number: 187929591

Start: 2628675

End: 2629460

Strand: Reverse

Name: prsA [H]

Synonym: Rpic_2516

Alternate gene names: 187929591

Gene position: 2629460-2628675 (Counterclockwise)

Preceding gene: 187929592

Following gene: 187929590

Centisome position: 66.69

GC content: 62.47

Gene sequence:

>786_bases
ATGAGCATGCAGGCAACGTCCGGCAGTGCAACCGTGGTGCGCATCAACGGTGTGGTGATCGACGCTGCGTTGATCGCAGA
GGAAGAGCAGCACCACGCAGGCGAGCCCGAGCCGCTGGCTGCGGCGGCCTGTGCGTTGGCAATCCACGAGTTGCTGAGGC
AACGCGCTGTGGCGTTGCAGCTCATTTCAGACAGCGATGCGCTGGATGATGCGTGCGTCGATGCGTTGCTCGAACGCGAG
CTGGCCGTACCCGAGCCAACCCGTGCCGATTGCGAGCGGTACTACCAGAACCACCCGGCTCGCTTCCGGCGCAACGATAT
CGTCTATGCCAGCCATATCCTGTTTGCGGTGACCGACCGTGCGCCGGTCGCGTTGCTGTTGCAAAAGGCGCAGCAGACAC
TGCAGCAGGTGTTGGAGGCCCCAGAAACATTCGAGGCCGTGGCGCGCGAAGTCTCCAATTGCCCATCTGCGGGCGTGGGC
GGCAGCCTTGGCCAGTTGTTGCGTGGCGATAGCGTTCCGGAGTTTGAGCGCGTGCTGTTCGATTCAACTGAAACGGGGGT
TCTGCCGCGCATCGTCAAGACGCGGTTCGGATTCCACGTTGTGCGCATCGAGCATCGCGTGGCGGGCGACACCGTGCCGT
TCGATGCGGTCGAGGCCGAGATTGCTCAATACCTTGAAGCGCGCGTCAGACACAAGGCCACGCAGCAATACGTGTCGATA
CTGGCTTCGCAGGCGCAAGTCGAAGGTGTGGATCTTGGGGCCGCCAACGGACCCCTGGTTCAATAG

Upstream 100 bases:

>100_bases
GCGGATGGTCCATATCTGGAGCGGCTTTGCGTCACTGGCGTATCTGATCCGGCCGTATCAGTTGGTGCGCAAGCGTTAAC
GCTGAATGGGGGGAGGCTTG

Downstream 100 bases:

>100_bases
GTCGGCAACGCACAGAGGAAGGGGAGCCAGCATGCGAGCACCAGGCGCAACGAACAATCAGGCCGGCGCCCCGGCCATTT
CGGCCCAAGCGTGGTCAGTG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSMQATSGSATVVRINGVVIDAALIAEEEQHHAGEPEPLAAAACALAIHELLRQRAVALQLISDSDALDDACVDALLERE
LAVPEPTRADCERYYQNHPARFRRNDIVYASHILFAVTDRAPVALLLQKAQQTLQQVLEAPETFEAVAREVSNCPSAGVG
GSLGQLLRGDSVPEFERVLFDSTETGVLPRIVKTRFGFHVVRIEHRVAGDTVPFDAVEAEIAQYLEARVRHKATQQYVSI
LASQAQVEGVDLGAANGPLVQ

Sequences:

>Translated_261_residues
MSMQATSGSATVVRINGVVIDAALIAEEEQHHAGEPEPLAAAACALAIHELLRQRAVALQLISDSDALDDACVDALLERE
LAVPEPTRADCERYYQNHPARFRRNDIVYASHILFAVTDRAPVALLLQKAQQTLQQVLEAPETFEAVAREVSNCPSAGVG
GSLGQLLRGDSVPEFERVLFDSTETGVLPRIVKTRFGFHVVRIEHRVAGDTVPFDAVEAEIAQYLEARVRHKATQQYVSI
LASQAQVEGVDLGAANGPLVQ
>Mature_260_residues
SMQATSGSATVVRINGVVIDAALIAEEEQHHAGEPEPLAAAACALAIHELLRQRAVALQLISDSDALDDACVDALLEREL
AVPEPTRADCERYYQNHPARFRRNDIVYASHILFAVTDRAPVALLLQKAQQTLQQVLEAPETFEAVAREVSNCPSAGVGG
SLGQLLRGDSVPEFERVLFDSTETGVLPRIVKTRFGFHVVRIEHRVAGDTVPFDAVEAEIAQYLEARVRHKATQQYVSIL
ASQAQVEGVDLGAANGPLVQ

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 28279; Mature: 28148

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMQATSGSATVVRINGVVIDAALIAEEEQHHAGEPEPLAAAACALAIHELLRQRAVALQ
CCCCCCCCCEEEEEECCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LISDSDALDDACVDALLERELAVPEPTRADCERYYQNHPARFRRNDIVYASHILFAVTDR
HHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCEEEHHHHHHEECCC
APVALLLQKAQQTLQQVLEAPETFEAVAREVSNCPSAGVGGSLGQLLRGDSVPEFERVLF
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHH
DSTETGVLPRIVKTRFGFHVVRIEHRVAGDTVPFDAVEAEIAQYLEARVRHKATQQYVSI
CCCCCCHHHHHHHHHHCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASQAQVEGVDLGAANGPLVQ
HHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SMQATSGSATVVRINGVVIDAALIAEEEQHHAGEPEPLAAAACALAIHELLRQRAVALQ
CCCCCCCCEEEEEECCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LISDSDALDDACVDALLERELAVPEPTRADCERYYQNHPARFRRNDIVYASHILFAVTDR
HHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHCCCEEEHHHHHHEECCC
APVALLLQKAQQTLQQVLEAPETFEAVAREVSNCPSAGVGGSLGQLLRGDSVPEFERVLF
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHH
DSTETGVLPRIVKTRFGFHVVRIEHRVAGDTVPFDAVEAEIAQYLEARVRHKATQQYVSI
CCCCCCHHHHHHHHHHCEEEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LASQAQVEGVDLGAANGPLVQ
HHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]