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The map label for this gene is pip [H]

Identifier: 187929564

GI number: 187929564

Start: 2602026

End: 2602970

Strand: Reverse

Name: pip [H]

Synonym: Rpic_2487

Alternate gene names: 187929564

Gene position: 2602970-2602026 (Counterclockwise)

Preceding gene: 187929570

Following gene: 187929562

Centisome position: 66.02

GC content: 68.25

Gene sequence:

>945_bases
ATGCCCACCTCCGACTGGCCAACCACATCCGCCCGCTTTCACCTGCGCACGCCGGACGGCCACTGCCTGCATGTGCGCCA
ATGCGGGCCTGACAGCGGAGAACCGTGGCTGGTGCTGCATGGCGGCCCGGGCAGCGGCTGCGCGCCTTCGATGGCTGCGT
GGTTCGATCCGCTGCGGCATCGCGCCGTGCTGCCGGACCAGCGCGGTGCCGGGCGCTCGCGACCCGCCGGCACGCTACGG
CGCAATACGGTGACGGCGCTGCTGGCCGATCTGGAGCAACTGCGCATTGCGCTCGGCATTGCGCGCTGGGGCGTGGTCGG
TGGGTCATGGGGCGCAGCGCTGGCGTTGGCCTATGCCGATCGCTTTCCCCATGCCGTATCGGCGCTGGTGCTGCGCGGCA
CCTTCCTGACCGGTTTCGACGATGTGCAGTCGTTGTTCAACGCGCGCGGCGCCGGTCGTGATCTCTTGCGAGGCGTCGGT
GGGCGAGGTGAGGGTTTTCCTGCGGCCCGTGGTCGTCTTCGCGTTGCAACAGACATGTTGCAGCCTGGTACAACTGTTCA
GAAATTGAACATTGCCACGGCATGGCAGCGTGCGGAACGTCGGCTGTTGGGCCTGTGGCCGCTGGCACGTCGCCAAACCT
GGCAGCAGCGCATGGCCCTCGTGCGCAAGTACCAGTTGCAGGCGCATTACCTGCATCGGCGAGCAGGGCTGGGGAAGGCA
GCGTTGCTGCGGGCGGCCACGCGCATCGGGGCGAGGGGTTTGCCGGTGACGCTGCTGCATGGGCGGGAAGACAAGGTTTG
CCGGCCCGGCAATGCGCTGCGGTTGTCTGTAGCGATCCCGCATGCGCGGTTGGTGTGGGTGCCGGGTGGGCACCTGGCGG
TGGGTGAGATGGCGAAAGCGCTGGGCGCCGCCATCCGTGCGTCGGCGTGGTCAGTCGGTGTCTGA

Upstream 100 bases:

>100_bases
TCCTCCTTGAGGGTTGGCATAGTTAGTGAATGCACAGCGTTGTTCAGCGGTTGCACAGGCGTTTGCCGAACGCAGCCGCA
TCGTCCTCAAGGCAACATCC

Downstream 100 bases:

>100_bases
AGGCAAGCCGCCGGCCTCGTCGATCCGGCGGTAGATTGTGTTGCGCGAAATGCCGAGCGCTTTCGCAGCGGCGGAAATGT
TGCCGTTGTGCGCCTGCACG

Product: Prolyl aminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MPTSDWPTTSARFHLRTPDGHCLHVRQCGPDSGEPWLVLHGGPGSGCAPSMAAWFDPLRHRAVLPDQRGAGRSRPAGTLR
RNTVTALLADLEQLRIALGIARWGVVGGSWGAALALAYADRFPHAVSALVLRGTFLTGFDDVQSLFNARGAGRDLLRGVG
GRGEGFPAARGRLRVATDMLQPGTTVQKLNIATAWQRAERRLLGLWPLARRQTWQQRMALVRKYQLQAHYLHRRAGLGKA
ALLRAATRIGARGLPVTLLHGREDKVCRPGNALRLSVAIPHARLVWVPGGHLAVGEMAKALGAAIRASAWSVGV

Sequences:

>Translated_314_residues
MPTSDWPTTSARFHLRTPDGHCLHVRQCGPDSGEPWLVLHGGPGSGCAPSMAAWFDPLRHRAVLPDQRGAGRSRPAGTLR
RNTVTALLADLEQLRIALGIARWGVVGGSWGAALALAYADRFPHAVSALVLRGTFLTGFDDVQSLFNARGAGRDLLRGVG
GRGEGFPAARGRLRVATDMLQPGTTVQKLNIATAWQRAERRLLGLWPLARRQTWQQRMALVRKYQLQAHYLHRRAGLGKA
ALLRAATRIGARGLPVTLLHGREDKVCRPGNALRLSVAIPHARLVWVPGGHLAVGEMAKALGAAIRASAWSVGV
>Mature_313_residues
PTSDWPTTSARFHLRTPDGHCLHVRQCGPDSGEPWLVLHGGPGSGCAPSMAAWFDPLRHRAVLPDQRGAGRSRPAGTLRR
NTVTALLADLEQLRIALGIARWGVVGGSWGAALALAYADRFPHAVSALVLRGTFLTGFDDVQSLFNARGAGRDLLRGVGG
RGEGFPAARGRLRVATDMLQPGTTVQKLNIATAWQRAERRLLGLWPLARRQTWQQRMALVRKYQLQAHYLHRRAGLGKAA
LLRAATRIGARGLPVTLLHGREDKVCRPGNALRLSVAIPHARLVWVPGGHLAVGEMAKALGAAIRASAWSVGV

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 33881; Mature: 33750

Theoretical pI: Translated: 12.18; Mature: 12.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTSDWPTTSARFHLRTPDGHCLHVRQCGPDSGEPWLVLHGGPGSGCAPSMAAWFDPLRH
CCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
RAVLPDQRGAGRSRPAGTLRRNTVTALLADLEQLRIALGIARWGVVGGSWGAALALAYAD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RFPHAVSALVLRGTFLTGFDDVQSLFNARGAGRDLLRGVGGRGEGFPAARGRLRVATDML
HCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHCCCEEEHHHHC
QPGTTVQKLNIATAWQRAERRLLGLWPLARRQTWQQRMALVRKYQLQAHYLHRRAGLGKA
CCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALLRAATRIGARGLPVTLLHGREDKVCRPGNALRLSVAIPHARLVWVPGGHLAVGEMAKA
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHH
LGAAIRASAWSVGV
HHHHHHHCCCCCCC
>Mature Secondary Structure 
PTSDWPTTSARFHLRTPDGHCLHVRQCGPDSGEPWLVLHGGPGSGCAPSMAAWFDPLRH
CCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
RAVLPDQRGAGRSRPAGTLRRNTVTALLADLEQLRIALGIARWGVVGGSWGAALALAYAD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RFPHAVSALVLRGTFLTGFDDVQSLFNARGAGRDLLRGVGGRGEGFPAARGRLRVATDML
HCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHCCCEEEHHHHC
QPGTTVQKLNIATAWQRAERRLLGLWPLARRQTWQQRMALVRKYQLQAHYLHRRAGLGKA
CCCCCEEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ALLRAATRIGARGLPVTLLHGREDKVCRPGNALRLSVAIPHARLVWVPGGHLAVGEMAKA
HHHHHHHHHCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHH
LGAAIRASAWSVGV
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]