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The map label for this gene is ndh [H]

Identifier: 187929513

GI number: 187929513

Start: 2539722

End: 2541056

Strand: Reverse

Name: ndh [H]

Synonym: Rpic_2434

Alternate gene names: 187929513

Gene position: 2541056-2539722 (Counterclockwise)

Preceding gene: 187929514

Following gene: 187929512

Centisome position: 64.45

GC content: 65.32

Gene sequence:

>1335_bases
ATGGCAGGGCAGACGGGTGGCGCAGGCGGTACGAACGGGCCTCGCATTGTGGTGGTCGGCGGGGGCGCCGGCGGGTTGGA
GCTTGCAACACGGCTCGGCGACAAGCTCGGCAAGCGCGGCGCGGCGCAGATCATTCTGGTCGACCGCAACCCCACACACA
TCTGGAAACCGCTGCTGCATGAAGTTGCTGCCGGCAGCATGGATCCGAACACGCATCAGCTCGAATACGCTGCGCAGGCG
CGCTGGCATGGCTTCGAATTCCAGCAGGGCGAGCTGAAGGGCCTCGATCGCGTCGCCAAATCCATCATGGTGTCCGGATG
CGTTGACGCGGACGGCACCGAGGTGCTTCCCGAGCGCGCCATTTCGTACGACACGCTGGTGCTGTCAATCGGCAGCGTGA
CGCATTTCTTCGGCGTGCCTGGCACGGCCGAGCACGCCATCGCCCTCGACACCGCATGGCAGGCCGAGCGCTTTCGCCGC
AGGCTCATCGCAGCGTGCATGCGCGCGCAGAACGGTGTGGGCGATGCACGTCCGCAGGTGGATATCGCCATCGTCGGGGC
GGGTGCCACGGGCGTCGAACTGTCGGCTGAGCTGCGCAACACCGCCCACGTGTTGGCGGCTTATGGGCTGCACAAGCTGG
ACCCGCGCCACGACATCCGCATCCATCTGATCGAAGGCGGTCCGCGTATTTTGCCGGTGCTCAAGGAGCGCATTTCGGCT
GCGACCACGGAGCTGCTGCGCAAGCTCGACGTGGACGTCATCACCAGCGAACGCGTGACCGAAGTCACCGCCAGCGCCGT
CAACACGGCCAGCGGCAAGTTCATTCCGGCGGATCTGACCGTGTGGGCTGCAGGCATCCGTGCACCGTCGGTGCTGGGCG
AACTGGGGCTGCCGGTGAACAAGCTGGGGCAGGTGATCGTTTCGCGCACGCTGCAAGTAGAAGGCGATGATTCGATCTAC
GCGTTTGGCGATTGCGCAAGCTGCCCCTGGCCCGAGGCGTCGTCCAGCGTGCCGCCGCGTGCCCAGGCTGCGCATCAGCA
AGCCACGTATCTGTTCGATGCGCTGCGCAAGCGCATGGACGGCAGGCCAGTCCAACCCTTCGCGTTCAAGGATCTCGGCT
CGCTGGTGTCGCTCGGCCATTTCAGCGCGGTCGGAAGCCTGATGGGCGGGCTGATCGGCGGTTCGATGTTCATCGAAGGC
TTGATGGCGCGGCTGATGTACACGTCGCTGTATCGCATGCACGTGCTGGCGCTGCACGGCTGGGTGCGCATGTCGGTCGA
TACGGTCATGCACTGGCTGCGCAGCAAGACGAATCCGCGCGTCAAGCTGCACTAG

Upstream 100 bases:

>100_bases
CGTATCCATGCGCCTGGGGTTGCGGCGGATTTTGCGTTGCAGCAGACTGCACCTGACAGATCGAGTGATCGAAAAGATTC
AACGGCTCCAGGAGAGGCAC

Downstream 100 bases:

>100_bases
GCCCGTCCTCGTGGCCGAGCCGGATGTCTGGCTCGGCAACAATGCATTTGCTTCGGTAGACTAGCCGCTTCGTTCACCGT
AACCGCCCGTGGGCGCGAGG

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAGQTGGAGGTNGPRIVVVGGGAGGLELATRLGDKLGKRGAAQIILVDRNPTHIWKPLLHEVAAGSMDPNTHQLEYAAQA
RWHGFEFQQGELKGLDRVAKSIMVSGCVDADGTEVLPERAISYDTLVLSIGSVTHFFGVPGTAEHAIALDTAWQAERFRR
RLIAACMRAQNGVGDARPQVDIAIVGAGATGVELSAELRNTAHVLAAYGLHKLDPRHDIRIHLIEGGPRILPVLKERISA
ATTELLRKLDVDVITSERVTEVTASAVNTASGKFIPADLTVWAAGIRAPSVLGELGLPVNKLGQVIVSRTLQVEGDDSIY
AFGDCASCPWPEASSSVPPRAQAAHQQATYLFDALRKRMDGRPVQPFAFKDLGSLVSLGHFSAVGSLMGGLIGGSMFIEG
LMARLMYTSLYRMHVLALHGWVRMSVDTVMHWLRSKTNPRVKLH

Sequences:

>Translated_444_residues
MAGQTGGAGGTNGPRIVVVGGGAGGLELATRLGDKLGKRGAAQIILVDRNPTHIWKPLLHEVAAGSMDPNTHQLEYAAQA
RWHGFEFQQGELKGLDRVAKSIMVSGCVDADGTEVLPERAISYDTLVLSIGSVTHFFGVPGTAEHAIALDTAWQAERFRR
RLIAACMRAQNGVGDARPQVDIAIVGAGATGVELSAELRNTAHVLAAYGLHKLDPRHDIRIHLIEGGPRILPVLKERISA
ATTELLRKLDVDVITSERVTEVTASAVNTASGKFIPADLTVWAAGIRAPSVLGELGLPVNKLGQVIVSRTLQVEGDDSIY
AFGDCASCPWPEASSSVPPRAQAAHQQATYLFDALRKRMDGRPVQPFAFKDLGSLVSLGHFSAVGSLMGGLIGGSMFIEG
LMARLMYTSLYRMHVLALHGWVRMSVDTVMHWLRSKTNPRVKLH
>Mature_443_residues
AGQTGGAGGTNGPRIVVVGGGAGGLELATRLGDKLGKRGAAQIILVDRNPTHIWKPLLHEVAAGSMDPNTHQLEYAAQAR
WHGFEFQQGELKGLDRVAKSIMVSGCVDADGTEVLPERAISYDTLVLSIGSVTHFFGVPGTAEHAIALDTAWQAERFRRR
LIAACMRAQNGVGDARPQVDIAIVGAGATGVELSAELRNTAHVLAAYGLHKLDPRHDIRIHLIEGGPRILPVLKERISAA
TTELLRKLDVDVITSERVTEVTASAVNTASGKFIPADLTVWAAGIRAPSVLGELGLPVNKLGQVIVSRTLQVEGDDSIYA
FGDCASCPWPEASSSVPPRAQAAHQQATYLFDALRKRMDGRPVQPFAFKDLGSLVSLGHFSAVGSLMGGLIGGSMFIEGL
MARLMYTSLYRMHVLALHGWVRMSVDTVMHWLRSKTNPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=431, Percent_Identity=49.8839907192575, Blast_Score=398, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6323515, Length=477, Percent_Identity=23.2704402515723, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320118, Length=465, Percent_Identity=24.7311827956989, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6323794, Length=466, Percent_Identity=22.9613733905579, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47568; Mature: 47437

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGQTGGAGGTNGPRIVVVGGGAGGLELATRLGDKLGKRGAAQIILVDRNPTHIWKPLLH
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHH
EVAAGSMDPNTHQLEYAAQARWHGFEFQQGELKGLDRVAKSIMVSGCVDADGTEVLPERA
HHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ISYDTLVLSIGSVTHFFGVPGTAEHAIALDTAWQAERFRRRLIAACMRAQNGVGDARPQV
CCHHHHEEEHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
DIAIVGAGATGVELSAELRNTAHVLAAYGLHKLDPRHDIRIHLIEGGPRILPVLKERISA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHH
ATTELLRKLDVDVITSERVTEVTASAVNTASGKFIPADLTVWAAGIRAPSVLGELGLPVN
HHHHHHHHHCCHHCCCHHHHHHHHHHHHCCCCCEEECCHHHHHHCCCCHHHHHHHCCCHH
KLGQVIVSRTLQVEGDDSIYAFGDCASCPWPEASSSVPPRAQAAHQQATYLFDALRKRMD
HHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GRPVQPFAFKDLGSLVSLGHFSAVGSLMGGLIGGSMFIEGLMARLMYTSLYRMHVLALHG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVRMSVDTVMHWLRSKTNPRVKLH
HHHHHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure 
AGQTGGAGGTNGPRIVVVGGGAGGLELATRLGDKLGKRGAAQIILVDRNPTHIWKPLLH
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHH
EVAAGSMDPNTHQLEYAAQARWHGFEFQQGELKGLDRVAKSIMVSGCVDADGTEVLPERA
HHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ISYDTLVLSIGSVTHFFGVPGTAEHAIALDTAWQAERFRRRLIAACMRAQNGVGDARPQV
CCHHHHEEEHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
DIAIVGAGATGVELSAELRNTAHVLAAYGLHKLDPRHDIRIHLIEGGPRILPVLKERISA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHH
ATTELLRKLDVDVITSERVTEVTASAVNTASGKFIPADLTVWAAGIRAPSVLGELGLPVN
HHHHHHHHHCCHHCCCHHHHHHHHHHHHCCCCCEEECCHHHHHHCCCCHHHHHHHCCCHH
KLGQVIVSRTLQVEGDDSIYAFGDCASCPWPEASSSVPPRAQAAHQQATYLFDALRKRMD
HHHHHHHHHHEEECCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GRPVQPFAFKDLGSLVSLGHFSAVGSLMGGLIGGSMFIEGLMARLMYTSLYRMHVLALHG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WVRMSVDTVMHWLRSKTNPRVKLH
HHHHHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]