BacMap

Definition	Ralstonia pickettii 12J chromosome chromosome 1, complete sequence.
Accession	NC_010682
Length	3,942,557

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The map label for this gene is fabG [H]

Identifier: 187929462

GI number: 187929462

Start: 2477142

End: 2477933

Strand: Reverse

Name: fabG [H]

Synonym: Rpic_2383

Alternate gene names: 187929462

Gene position: 2477933-2477142 (Counterclockwise)

Preceding gene: 187929463

Following gene: 187929461

Centisome position: 62.85

GC content: 66.16

Gene sequence:

>792_bases
ATGGACTTGGGGCTGAAAGGCAAGCGTGCGCTGGTGTGTGGCGCAAGCAAGGGATTGGGCTTTGCGTGCGCCGATGCGCT
GGCTGCCGAAGGCGTGGACGTGGTGATCGTCGCGCGCGGTGCCGAAGCGTTGTCGGCAGCGGCCGAGCGCATCCGCACGG
CGCACGGCGTGCGCGTGGAAGCAGTGGCGACCGACATCACCACGCCGGAAGGCCGTGCCGAAGCGCTGCTCGCATGCGAG
CGTCTGGGCGGCTCGCCCGACATCCTCATCAACAACGCAGGCGGCCCGCCGCCGGGCAACTTCCGCGATTGGGACCGCGA
CGTATGGAATGCCGCGCTCAACGCCAACATGCTCACGCCGATCGACCTCATCAAAGCCACCGTCGACAAGATGATCGAGC
GCCGCTGGGGCCGCATCGTCAATATCACCAGCGGTGCCGTCAAGGCGCCGATCGACGTGCTGGGTTTGTCCAACGGCGCG
CGCTCCGGCCTGACCGGCTTCGTTGCCGGCCTGGCGCGTGAAGTCGCCAAGCACGGCGTGACCATCAACAACCTGCTGCC
GGGCCAGTTCGAGACCGACCGCCTGACCAAGACGCTGGAGGCAGGCGCCAAGGCTGCCGGCATCAGCGCAGAAGAGAATT
TCGACCGCAAGCGGCAGGGCAATCCGGCTCGACGCTTTGGCCAACCGGCCGAATTTGGCGCCGTCTGTGCCTTCCTGTGT
AGCCAGCATGCCGGCTACCTGAACGCGCAAAACATCCTGCTGGATGGCGGCAGCTTCCCTGGCACCTTTTAA

Upstream 100 bases:

>100_bases
TGCCGGCAGCGCGCTGGTGCTTGCCGGTATGGCGCTGCTGTCACGCCGTCGCGGCTGACGGGCGGCCAATCCAAATAGCA
ATCACAAGGAGTCAGACAAG

Downstream 100 bases:

>100_bases
GCCAATCGACATGACCACCCTTACGCCCGCTACGCCCGAAAGCGCAGTTCGCAAACGCCGCGTCGCCCTGATCGCACACG
ACCACAAGAAAGACGACATG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MDLGLKGKRALVCGASKGLGFACADALAAEGVDVVIVARGAEALSAAAERIRTAHGVRVEAVATDITTPEGRAEALLACE
RLGGSPDILINNAGGPPPGNFRDWDRDVWNAALNANMLTPIDLIKATVDKMIERRWGRIVNITSGAVKAPIDVLGLSNGA
RSGLTGFVAGLAREVAKHGVTINNLLPGQFETDRLTKTLEAGAKAAGISAEENFDRKRQGNPARRFGQPAEFGAVCAFLC
SQHAGYLNAQNILLDGGSFPGTF

Sequences:

>Translated_263_residues
MDLGLKGKRALVCGASKGLGFACADALAAEGVDVVIVARGAEALSAAAERIRTAHGVRVEAVATDITTPEGRAEALLACE
RLGGSPDILINNAGGPPPGNFRDWDRDVWNAALNANMLTPIDLIKATVDKMIERRWGRIVNITSGAVKAPIDVLGLSNGA
RSGLTGFVAGLAREVAKHGVTINNLLPGQFETDRLTKTLEAGAKAAGISAEENFDRKRQGNPARRFGQPAEFGAVCAFLC
SQHAGYLNAQNILLDGGSFPGTF
>Mature_263_residues
MDLGLKGKRALVCGASKGLGFACADALAAEGVDVVIVARGAEALSAAAERIRTAHGVRVEAVATDITTPEGRAEALLACE
RLGGSPDILINNAGGPPPGNFRDWDRDVWNAALNANMLTPIDLIKATVDKMIERRWGRIVNITSGAVKAPIDVLGLSNGA
RSGLTGFVAGLAREVAKHGVTINNLLPGQFETDRLTKTLEAGAKAAGISAEENFDRKRQGNPARRFGQPAEFGAVCAFLC
SQHAGYLNAQNILLDGGSFPGTF

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=28.2352941176471, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=28.2352941176471, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI19923817, Length=257, Percent_Identity=28.0155642023346, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=29.3193717277487, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI33667109, Length=210, Percent_Identity=27.1428571428571, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=27.8350515463918, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=27.1653543307087, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4503301, Length=258, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI7705855, Length=197, Percent_Identity=28.4263959390863, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI126723750, Length=260, Percent_Identity=25, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=29.6703296703297, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI66933014, Length=202, Percent_Identity=24.7524752475248, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=209, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=33.2046332046332, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=26.6666666666667, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=28.4584980237154, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082100, Length=265, Percent_Identity=31.3207547169811, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082160, Length=265, Percent_Identity=29.0566037735849, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1789208, Length=263, Percent_Identity=28.8973384030418, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787905, Length=257, Percent_Identity=28.4046692607004, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=26.4367816091954, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=26.0869565217391, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=27.0588235294118, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=28.6245353159851, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=27.8810408921933, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=272, Percent_Identity=29.7794117647059, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=30.1115241635688, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.1368821292776, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=273, Percent_Identity=29.6703296703297, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=267, Percent_Identity=26.5917602996255, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=268, Percent_Identity=30.9701492537313, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=27.5471698113208, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17561272, Length=265, Percent_Identity=31.6981132075472, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=26.3358778625954, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=28.2527881040892, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=26.4591439688716, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=26.5917602996255, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=29.811320754717, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=26.8199233716475, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=27.6, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=263, Percent_Identity=26.615969581749, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=26.8, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=26.007326007326, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=26.7441860465116, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=24.907063197026, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=266, Percent_Identity=27.4436090225564, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=27.734375, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=269, Percent_Identity=30.4832713754647, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI23397609, Length=261, Percent_Identity=31.0344827586207, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=30.1075268817204, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=30.1075268817204, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=28.0155642023346, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24640442, Length=210, Percent_Identity=27.1428571428571, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27444; Mature: 27444

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLKGKRALVCGASKGLGFACADALAAEGVDVVIVARGAEALSAAAERIRTAHGVRVE
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCEEE
AVATDITTPEGRAEALLACERLGGSPDILINNAGGPPPGNFRDWDRDVWNAALNANMLTP
EEEECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCH
IDLIKATVDKMIERRWGRIVNITSGAVKAPIDVLGLSNGARSGLTGFVAGLAREVAKHGV
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHCCC
TINNLLPGQFETDRLTKTLEAGAKAAGISAEENFDRKRQGNPARRFGQPAEFGAVCAFLC
EEECCCCCCCCHHHHHHHHHHCCHHCCCCCHHCCHHHHCCCHHHHCCCCHHHHHHHHHHH
SQHAGYLNAQNILLDGGSFPGTF
HHCCCCCCCCEEEEECCCCCCCC
>Mature Secondary Structure
MDLGLKGKRALVCGASKGLGFACADALAAEGVDVVIVARGAEALSAAAERIRTAHGVRVE
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCEEE
AVATDITTPEGRAEALLACERLGGSPDILINNAGGPPPGNFRDWDRDVWNAALNANMLTP
EEEECCCCCCCHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCH
IDLIKATVDKMIERRWGRIVNITSGAVKAPIDVLGLSNGARSGLTGFVAGLAREVAKHGV
HHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHEEECCCCCCCHHHHHHHHHHHHHHHCCC
TINNLLPGQFETDRLTKTLEAGAKAAGISAEENFDRKRQGNPARRFGQPAEFGAVCAFLC
EEECCCCCCCCHHHHHHHHHHCCHHCCCCCHHCCHHHHCCCHHHHCCCCHHHHHHHHHHH
SQHAGYLNAQNILLDGGSFPGTF
HHCCCCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]