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The map label for this gene is nahR [H]

Identifier: 187929324

GI number: 187929324

Start: 2354850

End: 2355797

Strand: Reverse

Name: nahR [H]

Synonym: Rpic_2245

Alternate gene names: 187929324

Gene position: 2355797-2354850 (Counterclockwise)

Preceding gene: 187929331

Following gene: 187929322

Centisome position: 59.75

GC content: 63.4

Gene sequence:

>948_bases
ATGCACGGCAAAGATCACCTCGATACCTATCTCCTGCGCGTTCTCTACACGCTGCTCACCGAGCAGAGCGTGACCCGTAC
GGCGGTCAAGCTTGGCCAGTCACAGCCGGCCATCAGCAACACGCTCAAGCGCCTGCGCGAGATCACCGGCGACGCCATTC
TGGTGCGCGGCAAGAACGGCATGGTGCCGACCGAGCGGGGGCATGACTTGCTGTCGCTGGCCCAGCAAAGCCTGGAGGCG
ATGGAGCGCATCGCCCGACCTTCGCAGGATTTCGATCCCGGCAACACGACGCGCACGTTCCACCTGGGTGCACCGGACTA
TCTTGATGCCTTTTTCCTGCCCAACATCGTCGAGCGCCTACGCAAGCAGGCGCCGCACGCCAAGTTGGTGGTGCATCCGC
TCAATGCCGGGGTCGACTACCTGGCCGCCCTGGAGCAAGGCGGCATGGACCTGGTGATCGGCAACTGGCTTTCACCGCCC
GAACATCTGCACATTTCACCGCTGTTCGACGATGAAGTCGTCTGCATGCTGGGCGCACAGCACCCGCTGGCGCGCAAGGG
CATCTCGCTCAAGCACTATGTGGAGATGCCCCATCTGGCGCCTGCGCCATATGCCGTCATGCAGCGCAGCATGATCGATC
AGGCTCTTGCGGAGCAGGGGCTCAAGCGGCAGATCCAGGTGTCGCTGCCGTATTTCGGGCTGGTGCCATATGTGCTGATG
CGCACCGATCTGGTGTTCACCACCGGCCGCCAGTTCGCCGCGCACTGCGCCCAGTATTTGCCGATCCGCATCCTGCCGAC
ACCCATGGCATTTCCCAAGATGCGCTTCTATCAGCTCTGGCACGAGCGCAGCCACGCGGCGCCCGATGTGATGTGGCTGC
GCCGCATGATCGGCGAAGTGGCGGCCGAGTTACCGCAGCATCCGCAGTTGGAATCGGCGGTGGCCTGA

Upstream 100 bases:

>100_bases
CCGGTAGCGGTCTGGCGGCGCGGCGTGCAGGTGACATACACTGACAGCGTCCTCAAGCACGTTTTTTAGAAGGGTCGGCG
CAGCCGTTACCCGCCTCCAG

Downstream 100 bases:

>100_bases
ACTGAACCGCCGTCGTCCTGCCCTGCGGCGGGGCAGGCAGGAAGCTATTTTCCGGTTGCGACCGCCTTCCCGTAGTCCGG
GAAGAACACCTGCTCTCCGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNGMVPTERGHDLLSLAQQSLEA
MERIARPSQDFDPGNTTRTFHLGAPDYLDAFFLPNIVERLRKQAPHAKLVVHPLNAGVDYLAALEQGGMDLVIGNWLSPP
EHLHISPLFDDEVVCMLGAQHPLARKGISLKHYVEMPHLAPAPYAVMQRSMIDQALAEQGLKRQIQVSLPYFGLVPYVLM
RTDLVFTTGRQFAAHCAQYLPIRILPTPMAFPKMRFYQLWHERSHAAPDVMWLRRMIGEVAAELPQHPQLESAVA

Sequences:

>Translated_315_residues
MHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNGMVPTERGHDLLSLAQQSLEA
MERIARPSQDFDPGNTTRTFHLGAPDYLDAFFLPNIVERLRKQAPHAKLVVHPLNAGVDYLAALEQGGMDLVIGNWLSPP
EHLHISPLFDDEVVCMLGAQHPLARKGISLKHYVEMPHLAPAPYAVMQRSMIDQALAEQGLKRQIQVSLPYFGLVPYVLM
RTDLVFTTGRQFAAHCAQYLPIRILPTPMAFPKMRFYQLWHERSHAAPDVMWLRRMIGEVAAELPQHPQLESAVA
>Mature_315_residues
MHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNGMVPTERGHDLLSLAQQSLEA
MERIARPSQDFDPGNTTRTFHLGAPDYLDAFFLPNIVERLRKQAPHAKLVVHPLNAGVDYLAALEQGGMDLVIGNWLSPP
EHLHISPLFDDEVVCMLGAQHPLARKGISLKHYVEMPHLAPAPYAVMQRSMIDQALAEQGLKRQIQVSLPYFGLVPYVLM
RTDLVFTTGRQFAAHCAQYLPIRILPTPMAFPKMRFYQLWHERSHAAPDVMWLRRMIGEVAAELPQHPQLESAVA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=304, Percent_Identity=28.2894736842105, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790147, Length=306, Percent_Identity=25.4901960784314, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081904, Length=253, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35438; Mature: 35438

Theoretical pI: Translated: 8.28; Mature: 8.28

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCC
MVPTERGHDLLSLAQQSLEAMERIARPSQDFDPGNTTRTFHLGAPDYLDAFFLPNIVERL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
RKQAPHAKLVVHPLNAGVDYLAALEQGGMDLVIGNWLSPPEHLHISPLFDDEVVCMLGAQ
HHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCCCCCEEECCC
HPLARKGISLKHYVEMPHLAPAPYAVMQRSMIDQALAEQGLKRQIQVSLPYFGLVPYVLM
CCHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHH
RTDLVFTTGRQFAAHCAQYLPIRILPTPMAFPKMRFYQLWHERSHAAPDVMWLRRMIGEV
HHHHHHCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAELPQHPQLESAVA
HHHCCCCCCHHHHCC
>Mature Secondary Structure
MHGKDHLDTYLLRVLYTLLTEQSVTRTAVKLGQSQPAISNTLKRLREITGDAILVRGKNG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCCC
MVPTERGHDLLSLAQQSLEAMERIARPSQDFDPGNTTRTFHLGAPDYLDAFFLPNIVERL
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHH
RKQAPHAKLVVHPLNAGVDYLAALEQGGMDLVIGNWLSPPEHLHISPLFDDEVVCMLGAQ
HHHCCCCEEEEEECCCCHHHHHHHHHCCCEEEECCCCCCCCCEEECCCCCCCCCEEECCC
HPLARKGISLKHYVEMPHLAPAPYAVMQRSMIDQALAEQGLKRQIQVSLPYFGLVPYVLM
CCHHHHCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHH
RTDLVFTTGRQFAAHCAQYLPIRILPTPMAFPKMRFYQLWHERSHAAPDVMWLRRMIGEV
HHHHHHCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAELPQHPQLESAVA
HHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]