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The map label for this gene is nuoC

Identifier: 187929291

GI number: 187929291

Start: 2323120

End: 2323722

Strand: Reverse

Name: nuoC

Synonym: Rpic_2212

Alternate gene names: 187929291

Gene position: 2323722-2323120 (Counterclockwise)

Preceding gene: 187929292

Following gene: 187929290

Centisome position: 58.94

GC content: 62.19

Gene sequence:

>603_bases
ATGACCGACAAGCTTGCCACCCTGAAGGCCGCGCTGGAAAAGGCGCTGGGCAATCGCGTTCAAAGCCTGACCGAGTCGGT
CGGTGAACTCACCCTCGTGGTGAAGGCTGCCGATTACCTCGACGCCATGCGCACGCTGCGCGACGACGCTTCGCTCAAAT
TTGAACAGCTGATGGACTTGTGCGGCGTCGACTACGCCGACTACGGCGACGGTGCCTGGAACGGCCCGCGTTTCGCTGCG
GTGTCGCATCTGCTGTCGATCACGCACAACTGGCGCGTTCGCGTGCGCGTGTTTGCGCCGGACGATGACCTGCCCGTGGT
GTCGTCGGTGACCACGATCTGGAATTCCGCTGACTGGTTCGAGCGCGAAGCGTTCGACCTTTACGGTCTTGTGTTCGAAG
GCCATCCGGACCTGCGCCGCATCCTGACCGACTACGGCTTCATTGGCCACCCGTTCCGCAAGGACTTCCCCGTGTCGGGT
TACGTTGAAATGCGTTACGACCCGGTGCAGCGCCGCGTGGTCTACCAGCCGGTCACCATCGAGCCGCGCGAGATTACGCC
GCGTGTGATCCGTGAGGATCAATACGGTGGTCTGAAGCACTGA

Upstream 100 bases:

>100_bases
GTGCCGGGCTGCCCGCCGACGGCCGAAGCACTGATCTACGGCATCATTCAGCTGCAGGCCAAGATCCGTCGCACCAACAC
CATCGCGCGCAAGGCCTGAC

Downstream 100 bases:

>100_bases
AGGGCGCCCGAACATGGCAGATATCAAGAACTACACCCTGAACTTCGGTCCGCAACACCCGGCAGCACACGGCGTGCTGC
GCCTGGTGCTTGAGTTGGAC

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTDKLATLKAALEKALGNRVQSLTESVGELTLVVKAADYLDAMRTLRDDASLKFEQLMDLCGVDYADYGDGAWNGPRFAA
VSHLLSITHNWRVRVRVFAPDDDLPVVSSVTTIWNSADWFEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPVQRRVVYQPVTIEPREITPRVIREDQYGGLKH

Sequences:

>Translated_200_residues
MTDKLATLKAALEKALGNRVQSLTESVGELTLVVKAADYLDAMRTLRDDASLKFEQLMDLCGVDYADYGDGAWNGPRFAA
VSHLLSITHNWRVRVRVFAPDDDLPVVSSVTTIWNSADWFEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSG
YVEMRYDPVQRRVVYQPVTIEPREITPRVIREDQYGGLKH
>Mature_199_residues
TDKLATLKAALEKALGNRVQSLTESVGELTLVVKAADYLDAMRTLRDDASLKFEQLMDLCGVDYADYGDGAWNGPRFAAV
SHLLSITHNWRVRVRVFAPDDDLPVVSSVTTIWNSADWFEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGY
VEMRYDPVQRRVVYQPVTIEPREITPRVIREDQYGGLKH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=178, Percent_Identity=40.4494382022472, Blast_Score=136, Evalue=1e-32,
Organism=Escherichia coli, GI145693162, Length=109, Percent_Identity=33.9449541284404, Blast_Score=76, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI32563621, Length=176, Percent_Identity=40.9090909090909, Blast_Score=138, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71990788, Length=176, Percent_Identity=40.9090909090909, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24656494, Length=168, Percent_Identity=40.4761904761905, Blast_Score=133, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_RALPJ (B2U7Q9)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001899778.1
- ProteinModelPortal:   B2U7Q9
- SMR:   B2U7Q9
- GeneID:   6287760
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_2212
- HOGENOM:   HBG727675
- OMA:   VFAPDDD
- ProtClustDB:   PRK06074
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 22839; Mature: 22708

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKLATLKAALEKALGNRVQSLTESVGELTLVVKAADYLDAMRTLRDDASLKFEQLMDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
CGVDYADYGDGAWNGPRFAAVSHLLSITHNWRVRVRVFAPDDDLPVVSSVTTIWNSADWF
HCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHH
EREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPVQRRVVYQPVTI
HHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHEEEECCCCC
EPREITPRVIREDQYGGLKH
CCHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure 
TDKLATLKAALEKALGNRVQSLTESVGELTLVVKAADYLDAMRTLRDDASLKFEQLMDL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
CGVDYADYGDGAWNGPRFAAVSHLLSITHNWRVRVRVFAPDDDLPVVSSVTTIWNSADWF
HCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHH
EREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPVQRRVVYQPVTI
HHHHHHHEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECHHHHEEEECCCCC
EPREITPRVIREDQYGGLKH
CCHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA