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The map label for this gene is ureC [H]

Identifier: 187929263

GI number: 187929263

Start: 2294686

End: 2296404

Strand: Reverse

Name: ureC [H]

Synonym: Rpic_2184

Alternate gene names: 187929263

Gene position: 2296404-2294686 (Counterclockwise)

Preceding gene: 187929264

Following gene: 187929262

Centisome position: 58.25

GC content: 64.46

Gene sequence:

>1719_bases
ATGACATTGAAGATCAATCGCCGCGCCTATGCGGAAATGTTCGGCCCCACGACGGGCGACCGCCTGCGTCTGGCCGACAC
CGACCTCATCGTCGAAGTCGAGCGCGACTTCACCGTCTACGGCGAGGAAGTGAAATTCGGCGGCGGCAAGGTCATCCGCG
ACGGCATGGGCCAGAGCCAGCGCGAATCGAAAGACTGCACCGACACCGTCATCACCAACGCGCTGATCATCGACCACTGG
GGCATCGTCAAGGCTGACATCGGCCTGAAGAACGGGCGCATCTCGGCGATCGGCAAGGCGGGCAATCCGGACATCCAGCC
CGGCGTGACCATCGTCATCGGCCCCGGCACCGAGATCATCGCGGGCGAAGGCATGATCGTCACCGCCGGCGGCGTCGACA
CGCACATCCACTTCATCTGCCCGCAGCAGATCGATGAGGCGCTCAACAGCGGCGTGACGACGATGATTGGCGGCGGCACT
GGCCCCGCCACCGGCACCTATGCCACCACCTGCACGCCGGGCCCGTGGCACATGCAGCGCATGCTGCAGGCCGCGGATGC
GTACCCGATGAACATCGGCTTCCTCGGCAAGGGCAACGGCAGCCTGCCGGGCGCGCTGCGCGAGCAGATCGACGCAGGCG
CCATCGGCCTGAAGCTGCACGAAGACTGGGGCTCCACGCCCGCCGCCATCGATTGCTGCTTGGGCGTGGCCGACGACACC
GATACGCAGGTCGCCATCCACACCGATACGTTGAACGAATCGGGCTTCGTTGAAGCGACCGTCGCTGCGTTCAAGGGCCG
CACGATCCACACGTATCACACGGAAGGCGCGGGCGGCGGGCATGCACCGGACATCATCCGTGTGTGCGGTGAATCGAACG
TGCTGCCGTCATCGACCAACCCGACGCGGCCGTTCACCGTCAACACGCTGGACGAGCACCTCGACATGTTGATGGTGTGC
CATCACCTCGATGCGTCCATCGCCGAAGACATCGCCTTTGCCGAAAGCCGCATCCGCCGCGAGACGATCGCCGCCGAAGA
CATCCTGCACGACCTGGGCGCGTTCTCGATGATCTCCAGCGATTCGCAGGCCATGGGCCGCGTCGGCGAAGTCGTGCTGC
GTACGTGGCAGACCGCACACAAGATGAAGGTGCAGCGCGGCAAGCTGGCCGGTGATCCGAACGATGCGCGGGGCGGACAT
GACAACTTCCGCGTCAAGCGGTACGTGGCGAAGTACACGATCAACCCCGCGCTCACGCACGGCATCGCACATGAAGTCGG
CTCGGTTGAAGTCGGCAAGTGGGCAGACCTCGTGCTGTGGAAGCCTGCGTTCTTTGGCGTGAAGCCGAGCCTGATCCTGA
AGGGCGGGATGATTGCCTCTGCGGCGATGGGCGATGCGAATGCGTCGATCCCAACGCCGCAGCCAGTGCACTATCGGCCG
ATGTTTGGGGCAGCGGGCGGGGCGCTGGGGCGGACGTCGTTGACGTTCCTGTCGCAATCGGCTGCTGCGGCTGGCGTGGC
GGAGCAGTATGGGTTGGCCAAGACCACGGCGGTCGTCAAGGGCACGCGTACTGTGAGCAAGGCGGACATGATTCATAACG
ACTGGCAGCCGGATATTTCGGTGGATCCGGAGACGTATCAGGTGGTGGCGGATGGGACGGTGCTGACTTGTGAGCCGGCG
GAGGTGTTGCCGATGGCGCAGCGGTATTTCTTGTTCTAG

Upstream 100 bases:

>100_bases
GGGCAGGAGCGTACGGTCGAACTCGTGGCGCTGGCGGGTGATCGCGTGGTCTACGGCTTCGCCGGCCGTGTGATGGGCAA
GCTTTGAGCGAGACACGGAC

Downstream 100 bases:

>100_bases
CTGGTGGTGCGGGGTGGGCTCGGGTTTCTTGTTGTTGGTCCATCCGTCGTATCGTCCCCGGCAGGAGGTGAAACAAGGGA
TGCCACGCCGCTCCGAGATC

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha [H]

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MTLKINRRAYAEMFGPTTGDRLRLADTDLIVEVERDFTVYGEEVKFGGGKVIRDGMGQSQRESKDCTDTVITNALIIDHW
GIVKADIGLKNGRISAIGKAGNPDIQPGVTIVIGPGTEIIAGEGMIVTAGGVDTHIHFICPQQIDEALNSGVTTMIGGGT
GPATGTYATTCTPGPWHMQRMLQAADAYPMNIGFLGKGNGSLPGALREQIDAGAIGLKLHEDWGSTPAAIDCCLGVADDT
DTQVAIHTDTLNESGFVEATVAAFKGRTIHTYHTEGAGGGHAPDIIRVCGESNVLPSSTNPTRPFTVNTLDEHLDMLMVC
HHLDASIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVVLRTWQTAHKMKVQRGKLAGDPNDARGGH
DNFRVKRYVAKYTINPALTHGIAHEVGSVEVGKWADLVLWKPAFFGVKPSLILKGGMIASAAMGDANASIPTPQPVHYRP
MFGAAGGALGRTSLTFLSQSAAAAGVAEQYGLAKTTAVVKGTRTVSKADMIHNDWQPDISVDPETYQVVADGTVLTCEPA
EVLPMAQRYFLF

Sequences:

>Translated_572_residues
MTLKINRRAYAEMFGPTTGDRLRLADTDLIVEVERDFTVYGEEVKFGGGKVIRDGMGQSQRESKDCTDTVITNALIIDHW
GIVKADIGLKNGRISAIGKAGNPDIQPGVTIVIGPGTEIIAGEGMIVTAGGVDTHIHFICPQQIDEALNSGVTTMIGGGT
GPATGTYATTCTPGPWHMQRMLQAADAYPMNIGFLGKGNGSLPGALREQIDAGAIGLKLHEDWGSTPAAIDCCLGVADDT
DTQVAIHTDTLNESGFVEATVAAFKGRTIHTYHTEGAGGGHAPDIIRVCGESNVLPSSTNPTRPFTVNTLDEHLDMLMVC
HHLDASIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVVLRTWQTAHKMKVQRGKLAGDPNDARGGH
DNFRVKRYVAKYTINPALTHGIAHEVGSVEVGKWADLVLWKPAFFGVKPSLILKGGMIASAAMGDANASIPTPQPVHYRP
MFGAAGGALGRTSLTFLSQSAAAAGVAEQYGLAKTTAVVKGTRTVSKADMIHNDWQPDISVDPETYQVVADGTVLTCEPA
EVLPMAQRYFLF
>Mature_571_residues
TLKINRRAYAEMFGPTTGDRLRLADTDLIVEVERDFTVYGEEVKFGGGKVIRDGMGQSQRESKDCTDTVITNALIIDHWG
IVKADIGLKNGRISAIGKAGNPDIQPGVTIVIGPGTEIIAGEGMIVTAGGVDTHIHFICPQQIDEALNSGVTTMIGGGTG
PATGTYATTCTPGPWHMQRMLQAADAYPMNIGFLGKGNGSLPGALREQIDAGAIGLKLHEDWGSTPAAIDCCLGVADDTD
TQVAIHTDTLNESGFVEATVAAFKGRTIHTYHTEGAGGGHAPDIIRVCGESNVLPSSTNPTRPFTVNTLDEHLDMLMVCH
HLDASIAEDIAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVVLRTWQTAHKMKVQRGKLAGDPNDARGGHD
NFRVKRYVAKYTINPALTHGIAHEVGSVEVGKWADLVLWKPAFFGVKPSLILKGGMIASAAMGDANASIPTPQPVHYRPM
FGAAGGALGRTSLTFLSQSAAAAGVAEQYGLAKTTAVVKGTRTVSKADMIHNDWQPDISVDPETYQVVADGTVLTCEPAE
VLPMAQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950 [H]

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha [H]

EC number: =3.5.1.5 [H]

Molecular weight: Translated: 60829; Mature: 60698

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS01120 UREASE_1 ; PS00145 UREASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLKINRRAYAEMFGPTTGDRLRLADTDLIVEVERDFTVYGEEVKFGGGKVIRDGMGQSQ
CEEEECCHHHHHHHCCCCCCEEEEECCEEEEEEECCEEEECCEEEECCCEEEECCCCCCH
RESKDCTDTVITNALIIDHWGIVKADIGLKNGRISAIGKAGNPDIQPGVTIVIGPGTEII
HHCCCHHHHHHHCEEEEECCCEEEEECCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEE
AGEGMIVTAGGVDTHIHFICPQQIDEALNSGVTTMIGGGTGPATGTYATTCTPGPWHMQR
ECCCEEEEECCCCEEEEEECHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCHHHHHH
MLQAADAYPMNIGFLGKGNGSLPGALREQIDAGAIGLKLHEDWGSTPAAIDCCLGVADDT
HHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCEEEEEEECCCCCCCHHHHHEEECCCCC
DTQVAIHTDTLNESGFVEATVAAFKGRTIHTYHTEGAGGGHAPDIIRVCGESNVLPSSTN
CCEEEEEECCCCCCCCEEEEHHHHCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCC
PTRPFTVNTLDEHLDMLMVCHHLDASIAEDIAFAESRIRRETIAAEDILHDLGAFSMISS
CCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSQAMGRVGEVVLRTWQTAHKMKVQRGKLAGDPNDARGGHDNFRVKRYVAKYTINPALTH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEEEEEEEECCHHHHH
GIAHEVGSVEVGKWADLVLWKPAFFGVKPSLILKGGMIASAAMGDANASIPTPQPVHYRP
HHHHHCCCEECCCCEEEEEECCHHHCCCHHEEEECCEEEEEECCCCCCCCCCCCCCEECC
MFGAAGGALGRTSLTFLSQSAAAAGVAEQYGLAKTTAVVKGTRTVSKADMIHNDWQPDIS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHEEEECCCCHHHHHHHCCCCCCCCC
VDPETYQVVADGTVLTCEPAEVLPMAQRYFLF
CCCCEEEEEECCEEEEECCHHHHHHHHHHHCC
>Mature Secondary Structure 
TLKINRRAYAEMFGPTTGDRLRLADTDLIVEVERDFTVYGEEVKFGGGKVIRDGMGQSQ
EEEECCHHHHHHHCCCCCCEEEEECCEEEEEEECCEEEECCEEEECCCEEEECCCCCCH
RESKDCTDTVITNALIIDHWGIVKADIGLKNGRISAIGKAGNPDIQPGVTIVIGPGTEII
HHCCCHHHHHHHCEEEEECCCEEEEECCCCCCCEEEEECCCCCCCCCCEEEEECCCCEEE
AGEGMIVTAGGVDTHIHFICPQQIDEALNSGVTTMIGGGTGPATGTYATTCTPGPWHMQR
ECCCEEEEECCCCEEEEEECHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCHHHHHH
MLQAADAYPMNIGFLGKGNGSLPGALREQIDAGAIGLKLHEDWGSTPAAIDCCLGVADDT
HHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCCEEEEEEECCCCCCCHHHHHEEECCCCC
DTQVAIHTDTLNESGFVEATVAAFKGRTIHTYHTEGAGGGHAPDIIRVCGESNVLPSSTN
CCEEEEEECCCCCCCCEEEEHHHHCCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCC
PTRPFTVNTLDEHLDMLMVCHHLDASIAEDIAFAESRIRRETIAAEDILHDLGAFSMISS
CCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DSQAMGRVGEVVLRTWQTAHKMKVQRGKLAGDPNDARGGHDNFRVKRYVAKYTINPALTH
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHEEEEEEEEECCHHHHH
GIAHEVGSVEVGKWADLVLWKPAFFGVKPSLILKGGMIASAAMGDANASIPTPQPVHYRP
HHHHHCCCEECCCCEEEEEECCHHHCCCHHEEEECCEEEEEECCCCCCCCCCCCCCEECC
MFGAAGGALGRTSLTFLSQSAAAAGVAEQYGLAKTTAVVKGTRTVSKADMIHNDWQPDIS
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHEEEECCCCHHHHHHHCCCCCCCCC
VDPETYQVVADGTVLTCEPAEVLPMAQRYFLF
CCCCEEEEEECCEEEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]