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The map label for this gene is 187929242

Identifier: 187929242

GI number: 187929242

Start: 2276633

End: 2277778

Strand: Reverse

Name: 187929242

Synonym: Rpic_2163

Alternate gene names: NA

Gene position: 2277778-2276633 (Counterclockwise)

Preceding gene: 187929243

Following gene: 187929231

Centisome position: 57.77

GC content: 64.83

Gene sequence:

>1146_bases
ATGACTGCCAATCAACCGCACATCTCCAGCGCGTTCGACAGCGGCGCCATCGAAATCGTCGATGCCGCACGCGCCGATGC
CATCCGCCTGCGCATTCGCCGCGATTCGCACGCTGACTTCACGCAGTGGTTCCACTTTCGCCTGCAAGGCGTGCAGGGCC
AGGCCTGCAAGTTGGCCCTGGAAAACGCCGGCGAATGCACCTACGCCTCCGGCTGGAAGGACTACCGCGCCGTCGCCTCG
TATGACCGCGAGCACTGGTTTCGTGTGCCGACCCGCTATGACGGCAAGACGTTGACGGTCGAGGTGACGCCCGAGCACGA
CAGCATCTGGTTTGCCTATTTCGAGCCGTATTCGGACGAGCGACACCTTTCGCTCGTGGCCGCTGCGCAAACGCAGCCGG
GCGTGCGCACGCAGCGCCTGGGGCAAACGGTGCAGGGCCGCGACATGACCAGCATCACCGTCGGTGAACCCGGCCCCGGC
AAGAAAAACGTGTGGATCATCGCGCGCCAGCATCCGGGCGAGACGATGGCCGAATGGTTCGTTGAAGGGCTGCTCGCACG
CCTGACGCGTCAGGGTGTCTGGCGCGGCGATCCCATCGGCCGTGTGCTCGCCGAGCGCGCCGTCTTCCATATCGTGCCGA
ACATGAACCCGGATGGCTCGTCCCTGGGCAACCTGCGCACCAATGCCGCAGGCGCCAACCTGAACCGCGAGTGGATGGAA
CCCGACGCGCAGCGCAGTCCCGAGGTGTTGGCTGTGCGGCAGGCCATCGAGCAAACCGGCGTCGACCTGTTTTTCGACAT
CCACGGCGACGAGGCGCTGCCTTATGTGTTTGTGGCCGGCAGTGAAATGCTGCCCGGCTTTACCGATGCACAGCGTGCCG
ATCAGGACCGCTTTGTCGCGGCCTTCCTGCGGGCATCACCGGATTTCCAGACGCGATACGGCTACGAGGCCAGCAGGTAC
AACGAAGACGCGCTCAAGCTCGCCTCCAAGTACATCGGCCACACCTATGGCTGCCTGTCGTTGACGCTGGAAATGCCGTT
CAAGGACAACGCCGACCTGCCCGACGCACGCGTGGGCTGGGACGGCGCCCGCAGCGCCGCTTTGGGTGCGGCCATGCTGC
AGGCGATCCTGGAGTATCTCGGCTGA

Upstream 100 bases:

>100_bases
TCAAGGCGTTCGATGTCGACGGCTATGCCTTTGCCGCTGCCGATTCCGACGACGAGCGCTGGGTCTTCCGCCGCAAGCTC
ACCTGATCGCAGGATCTGAC

Downstream 100 bases:

>100_bases
AGACAAACGCTGCGCCGCCTGTGTGGGCGGCGCGTTGCGCTTAGTTGGAAGACGACTTCTTCGTCGTCTTCTTTGCCGTC
GACTTGGCGGTGGATTTGCT

Product: peptidase M14 carboxypeptidase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MTANQPHISSAFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACKLALENAGECTYASGWKDYRAVAS
YDREHWFRVPTRYDGKTLTVEVTPEHDSIWFAYFEPYSDERHLSLVAAAQTQPGVRTQRLGQTVQGRDMTSITVGEPGPG
KKNVWIIARQHPGETMAEWFVEGLLARLTRQGVWRGDPIGRVLAERAVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
PDAQRSPEVLAVRQAIEQTGVDLFFDIHGDEALPYVFVAGSEMLPGFTDAQRADQDRFVAAFLRASPDFQTRYGYEASRY
NEDALKLASKYIGHTYGCLSLTLEMPFKDNADLPDARVGWDGARSAALGAAMLQAILEYLG

Sequences:

>Translated_381_residues
MTANQPHISSAFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACKLALENAGECTYASGWKDYRAVAS
YDREHWFRVPTRYDGKTLTVEVTPEHDSIWFAYFEPYSDERHLSLVAAAQTQPGVRTQRLGQTVQGRDMTSITVGEPGPG
KKNVWIIARQHPGETMAEWFVEGLLARLTRQGVWRGDPIGRVLAERAVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
PDAQRSPEVLAVRQAIEQTGVDLFFDIHGDEALPYVFVAGSEMLPGFTDAQRADQDRFVAAFLRASPDFQTRYGYEASRY
NEDALKLASKYIGHTYGCLSLTLEMPFKDNADLPDARVGWDGARSAALGAAMLQAILEYLG
>Mature_380_residues
TANQPHISSAFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACKLALENAGECTYASGWKDYRAVASY
DREHWFRVPTRYDGKTLTVEVTPEHDSIWFAYFEPYSDERHLSLVAAAQTQPGVRTQRLGQTVQGRDMTSITVGEPGPGK
KNVWIIARQHPGETMAEWFVEGLLARLTRQGVWRGDPIGRVLAERAVFHIVPNMNPDGSSLGNLRTNAAGANLNREWMEP
DAQRSPEVLAVRQAIEQTGVDLFFDIHGDEALPYVFVAGSEMLPGFTDAQRADQDRFVAAFLRASPDFQTRYGYEASRYN
EDALKLASKYIGHTYGCLSLTLEMPFKDNADLPDARVGWDGARSAALGAAMLQAILEYLG

Specific function: Unknown

COG id: COG2866

COG function: function code E; Predicted carboxypeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI190194403, Length=377, Percent_Identity=28.9124668435013, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI31657119, Length=311, Percent_Identity=26.3665594855305, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI120444924, Length=211, Percent_Identity=30.8056872037915, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI170763513, Length=325, Percent_Identity=24.9230769230769, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI222352158, Length=306, Percent_Identity=25.1633986928105, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI78482633, Length=97, Percent_Identity=34.020618556701, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI118421091, Length=109, Percent_Identity=32.1100917431193, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI115533904, Length=412, Percent_Identity=25, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193202888, Length=331, Percent_Identity=25.6797583081571, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571179, Length=201, Percent_Identity=28.3582089552239, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641847, Length=201, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161077807, Length=201, Percent_Identity=28.3582089552239, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24641845, Length=201, Percent_Identity=28.3582089552239, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000834 [H]

Pfam domain/function: PF00246 Peptidase_M14 [H]

EC number: NA

Molecular weight: Translated: 42473; Mature: 42342

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANQPHISSAFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACKLAL
CCCCCCCCHHHCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEE
ENAGECTYASGWKDYRAVASYDREHWFRVPTRYDGKTLTVEVTPEHDSIWFAYFEPYSDE
CCCCCCEECCCCHHHHHHHHCCCHHEEECCCCCCCEEEEEEEECCCCCEEEEEECCCCCC
RHLSLVAAAQTQPGVRTQRLGQTVQGRDMTSITVGEPGPGKKNVWIIARQHPGETMAEWF
CEEEEEEECCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHH
VEGLLARLTRQGVWRGDPIGRVLAERAVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCC
PDAQRSPEVLAVRQAIEQTGVDLFFDIHGDEALPYVFVAGSEMLPGFTDAQRADQDRFVA
CCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHCCHHHHHH
AFLRASPDFQTRYGYEASRYNEDALKLASKYIGHTYGCLSLTLEMPFKDNADLPDARVGW
HHHHCCCCCHHHCCCCHHHCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCC
DGARSAALGAAMLQAILEYLG
CCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TANQPHISSAFDSGAIEIVDAARADAIRLRIRRDSHADFTQWFHFRLQGVQGQACKLAL
CCCCCCCHHHCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCCEEEEEE
ENAGECTYASGWKDYRAVASYDREHWFRVPTRYDGKTLTVEVTPEHDSIWFAYFEPYSDE
CCCCCCEECCCCHHHHHHHHCCCHHEEECCCCCCCEEEEEEEECCCCCEEEEEECCCCCC
RHLSLVAAAQTQPGVRTQRLGQTVQGRDMTSITVGEPGPGKKNVWIIARQHPGETMAEWF
CEEEEEEECCCCCCCHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHH
VEGLLARLTRQGVWRGDPIGRVLAERAVFHIVPNMNPDGSSLGNLRTNAAGANLNREWME
HHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCHHHCC
PDAQRSPEVLAVRQAIEQTGVDLFFDIHGDEALPYVFVAGSEMLPGFTDAQRADQDRFVA
CCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCCCCCHHHCCHHHHHH
AFLRASPDFQTRYGYEASRYNEDALKLASKYIGHTYGCLSLTLEMPFKDNADLPDARVGW
HHHHCCCCCHHHCCCCHHHCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCCC
DGARSAALGAAMLQAILEYLG
CCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8320209 [H]