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The map label for this gene is yyaJ [H]

Identifier: 187929142

GI number: 187929142

Start: 2174481

End: 2175920

Strand: Reverse

Name: yyaJ [H]

Synonym: Rpic_2063

Alternate gene names: 187929142

Gene position: 2175920-2174481 (Counterclockwise)

Preceding gene: 187929143

Following gene: 187929140

Centisome position: 55.19

GC content: 63.82

Gene sequence:

>1440_bases
ATGCAACGCCCCCTGACAGCGGACAGCGCGCCGACTGCCATCGCTCAACACGATCAAGACACCCGCGCCGCCACGGCGCT
TTCTTCGCGGATGGACCGCTTGCCCATCACACGTAACCTGTGGATGCTAGTGCTGTTGATTTCGCTGGGTGGCTTTTTCG
AGGTCTACGATCTGATCTTCACGGGCTATATCGCGCCCGGTATGGAAAAAAGCGGGCTGCTCAAGGCCACGACCGATGCG
TTCTTCGGGCTGCATGGCATGGCCGGCTTCATTGCCGCCACGTTTGCGGGGCTCTTCGTCGGCACGTTCGGCTTGGGCTG
GCTGCCCGATCGTTATGGGCGCCGCACGGTGTTCACGGTATCGCTGCTGTGGTACTCGATCGGCTCCGCCATCATGGCGT
GCCAGCAGAGCCCCGAAGGCCTGCTGATCTGGCGCTTTCTCACCGGCATCGGTGTCGGCATCGAGATCGTGACCATCGAC
AGCTACGTCACCGAACTCGTGCCGCAGCATATGCGCGGCCGCGCCATGGCGTTCAATCAGATGGTGATGTTTGCCGCCGC
ACCCGCTGCGGCCATTCTGTCGTACTGGCTCGTGCCGACCACCCTGCTGGGGTTCGAAGGCTGGCGCTGGGTGGTGCTGT
TGGGCTCTGCCGGCGCGGTGCTGGTGTGGTTCATCCGCCGCGCCGTACCGGAAAGCCCGCGCTGGCTGGCCATGCATGGC
CATATCGACCAGGCAGATGCCGTTGTCCGCCAGATGGAAGCCGCCGCCGAGCGCGAATCCGGCAAAGCCCTGCCACCGCC
GCTGCAGGCCGTCGTGCAGCCGCCGCACCGCCGCGCATCGCTGGCGGAACTGTGGCGCCCGCCGTATCGCTCGCGCCTGA
TCATGCTGATCGTCTTCAACTTCTGCCAGGCCATCGGCTACTACGGCTTTGCCAACTGGGTGCCGACGCTGCTCATCGGC
CACGGCATCACCGTGACCAAGAGCCTCCTGTATTCGTTCATCATCGCCATTGCGCTGCCCGTCGGGCCGTTGCTGGCCAT
GGCCTATGCCGACCGCATCCAGCGCAAGTGGCTGATCGTTGGTGCCGCGTTTGCCGTCATCGTGTTCGGCGTGACGTTCG
GGCAACTGAAAGATCCACTCGCGTTGATCGTGCTGGGCGTGCTGATCAGCCTCGCTGGGCAGACCATTTCGGTGTGCTAT
CACGCCTACCAGGCCGAGCTGTTCCCGACCTTCATCCGCTGTCGCGCCAATGGCATCGTGTATTCGGCCAGCCGCATCGG
CGCCATGTTCTCGGGCTTTTTGATTGCCTTCCTGTTGCGGCACTTAGGCGTGCCGGGCGTGTTTGCGGGGATCACCGTAT
GCATGCTGGTGGTGATGCTGGCGATTGGCGGCTTCGGGCCGAAGAGCAACGGCCTGCGGCTGGAAGAGCTGTCGCACTAG

Upstream 100 bases:

>100_bases
ACCGAGACGACGGTCTTGCCTGCGCGGGAATACGATGCCGATACCGGCGCCCCTGGCCCAACGCTCGATAGAAGCGCGGC
CATGCGTTAAGGAGACAACC

Downstream 100 bases:

>100_bases
CCCCACCGGAACACCGTAGCGCTCACGACGCGGAAGTGGTTTTCCGCGTCGTTTTCTTTTGCCGGGCAGGTGTTGTCGGT
TCGATAGCGGCAGTGGCGTC

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MQRPLTADSAPTAIAQHDQDTRAATALSSRMDRLPITRNLWMLVLLISLGGFFEVYDLIFTGYIAPGMEKSGLLKATTDA
FFGLHGMAGFIAATFAGLFVGTFGLGWLPDRYGRRTVFTVSLLWYSIGSAIMACQQSPEGLLIWRFLTGIGVGIEIVTID
SYVTELVPQHMRGRAMAFNQMVMFAAAPAAAILSYWLVPTTLLGFEGWRWVVLLGSAGAVLVWFIRRAVPESPRWLAMHG
HIDQADAVVRQMEAAAERESGKALPPPLQAVVQPPHRRASLAELWRPPYRSRLIMLIVFNFCQAIGYYGFANWVPTLLIG
HGITVTKSLLYSFIIAIALPVGPLLAMAYADRIQRKWLIVGAAFAVIVFGVTFGQLKDPLALIVLGVLISLAGQTISVCY
HAYQAELFPTFIRCRANGIVYSASRIGAMFSGFLIAFLLRHLGVPGVFAGITVCMLVVMLAIGGFGPKSNGLRLEELSH

Sequences:

>Translated_479_residues
MQRPLTADSAPTAIAQHDQDTRAATALSSRMDRLPITRNLWMLVLLISLGGFFEVYDLIFTGYIAPGMEKSGLLKATTDA
FFGLHGMAGFIAATFAGLFVGTFGLGWLPDRYGRRTVFTVSLLWYSIGSAIMACQQSPEGLLIWRFLTGIGVGIEIVTID
SYVTELVPQHMRGRAMAFNQMVMFAAAPAAAILSYWLVPTTLLGFEGWRWVVLLGSAGAVLVWFIRRAVPESPRWLAMHG
HIDQADAVVRQMEAAAERESGKALPPPLQAVVQPPHRRASLAELWRPPYRSRLIMLIVFNFCQAIGYYGFANWVPTLLIG
HGITVTKSLLYSFIIAIALPVGPLLAMAYADRIQRKWLIVGAAFAVIVFGVTFGQLKDPLALIVLGVLISLAGQTISVCY
HAYQAELFPTFIRCRANGIVYSASRIGAMFSGFLIAFLLRHLGVPGVFAGITVCMLVVMLAIGGFGPKSNGLRLEELSH
>Mature_479_residues
MQRPLTADSAPTAIAQHDQDTRAATALSSRMDRLPITRNLWMLVLLISLGGFFEVYDLIFTGYIAPGMEKSGLLKATTDA
FFGLHGMAGFIAATFAGLFVGTFGLGWLPDRYGRRTVFTVSLLWYSIGSAIMACQQSPEGLLIWRFLTGIGVGIEIVTID
SYVTELVPQHMRGRAMAFNQMVMFAAAPAAAILSYWLVPTTLLGFEGWRWVVLLGSAGAVLVWFIRRAVPESPRWLAMHG
HIDQADAVVRQMEAAAERESGKALPPPLQAVVQPPHRRASLAELWRPPYRSRLIMLIVFNFCQAIGYYGFANWVPTLLIG
HGITVTKSLLYSFIIAIALPVGPLLAMAYADRIQRKWLIVGAAFAVIVFGVTFGQLKDPLALIVLGVLISLAGQTISVCY
HAYQAELFPTFIRCRANGIVYSASRIGAMFSGFLIAFLLRHLGVPGVFAGITVCMLVVMLAIGGFGPKSNGLRLEELSH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI166064021, Length=416, Percent_Identity=26.9230769230769, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI203098995, Length=262, Percent_Identity=28.2442748091603, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI4506999, Length=365, Percent_Identity=25.7534246575342, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI7662270, Length=338, Percent_Identity=21.301775147929, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI302148518, Length=361, Percent_Identity=24.0997229916898, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI4507005, Length=405, Percent_Identity=23.9506172839506, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI24308167, Length=463, Percent_Identity=21.8142548596112, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI216548223, Length=292, Percent_Identity=25, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI21553331, Length=195, Percent_Identity=26.1538461538462, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI296080721, Length=369, Percent_Identity=25.2032520325203, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI296080734, Length=372, Percent_Identity=24.7311827956989, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI23510410, Length=355, Percent_Identity=25.3521126760563, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI296080719, Length=369, Percent_Identity=25.2032520325203, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI24497499, Length=369, Percent_Identity=25.2032520325203, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI262399383, Length=261, Percent_Identity=21.8390804597701, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI148664184, Length=365, Percent_Identity=23.013698630137, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI24497490, Length=408, Percent_Identity=24.7549019607843, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1788068, Length=478, Percent_Identity=28.8702928870293, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI1788074, Length=462, Percent_Identity=27.7056277056277, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786229, Length=468, Percent_Identity=26.9230769230769, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87082159, Length=423, Percent_Identity=27.1867612293144, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790463, Length=484, Percent_Identity=24.1735537190083, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1789207, Length=374, Percent_Identity=23.5294117647059, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082404, Length=427, Percent_Identity=22.9508196721311, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789312, Length=178, Percent_Identity=27.5280898876405, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI87082231, Length=167, Percent_Identity=30.5389221556886, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565978, Length=292, Percent_Identity=25.6849315068493, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI212645980, Length=248, Percent_Identity=27.0161290322581, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323653, Length=471, Percent_Identity=26.1146496815287, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319718, Length=326, Percent_Identity=26.3803680981595, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321100, Length=528, Percent_Identity=23.6742424242424, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324469, Length=382, Percent_Identity=23.0366492146597, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24640198, Length=463, Percent_Identity=22.2462203023758, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640196, Length=463, Percent_Identity=22.2462203023758, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640200, Length=463, Percent_Identity=22.2462203023758, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19922616, Length=396, Percent_Identity=22.979797979798, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI161080349, Length=258, Percent_Identity=23.6434108527132, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24654932, Length=258, Percent_Identity=23.6434108527132, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI17737517, Length=258, Percent_Identity=23.6434108527132, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161080351, Length=258, Percent_Identity=23.6434108527132, Blast_Score=66, Evalue=5e-11,
Organism=Drosophila melanogaster, GI161080353, Length=258, Percent_Identity=23.6434108527132, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 52342; Mature: 52342

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRPLTADSAPTAIAQHDQDTRAATALSSRMDRLPITRNLWMLVLLISLGGFFEVYDLIF
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
TGYIAPGMEKSGLLKATTDAFFGLHGMAGFIAATFAGLFVGTFGLGWLPDRYGRRTVFTV
HHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
SLLWYSIGSAIMACQQSPEGLLIWRFLTGIGVGIEIVTIDSYVTELVPQHMRGRAMAFNQ
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHH
MVMFAAAPAAAILSYWLVPTTLLGFEGWRWVVLLGSAGAVLVWFIRRAVPESPRWLAMHG
HHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEC
HIDQADAVVRQMEAAAERESGKALPPPLQAVVQPPHRRASLAELWRPPYRSRLIMLIVFN
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
FCQAIGYYGFANWVPTLLIGHGITVTKSLLYSFIIAIALPVGPLLAMAYADRIQRKWLIV
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAFAVIVFGVTFGQLKDPLALIVLGVLISLAGQTISVCYHAYQAELFPTFIRCRANGIV
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEE
YSASRIGAMFSGFLIAFLLRHLGVPGVFAGITVCMLVVMLAIGGFGPKSNGLRLEELSH
EEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCC
>Mature Secondary Structure
MQRPLTADSAPTAIAQHDQDTRAATALSSRMDRLPITRNLWMLVLLISLGGFFEVYDLIF
CCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHH
TGYIAPGMEKSGLLKATTDAFFGLHGMAGFIAATFAGLFVGTFGLGWLPDRYGRRTVFTV
HHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
SLLWYSIGSAIMACQQSPEGLLIWRFLTGIGVGIEIVTIDSYVTELVPQHMRGRAMAFNQ
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCHHHHHHH
MVMFAAAPAAAILSYWLVPTTLLGFEGWRWVVLLGSAGAVLVWFIRRAVPESPRWLAMHG
HHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCEEEEEC
HIDQADAVVRQMEAAAERESGKALPPPLQAVVQPPHRRASLAELWRPPYRSRLIMLIVFN
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
FCQAIGYYGFANWVPTLLIGHGITVTKSLLYSFIIAIALPVGPLLAMAYADRIQRKWLIV
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAFAVIVFGVTFGQLKDPLALIVLGVLISLAGQTISVCYHAYQAELFPTFIRCRANGIV
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCEE
YSASRIGAMFSGFLIAFLLRHLGVPGVFAGITVCMLVVMLAIGGFGPKSNGLRLEELSH
EEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]