Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 187929056

GI number: 187929056

Start: 2084529

End: 2085050

Strand: Reverse

Name: infC [H]

Synonym: Rpic_1976

Alternate gene names: 187929056

Gene position: 2085050-2084529 (Counterclockwise)

Preceding gene: 187929057

Following gene: 187929055

Centisome position: 52.89

GC content: 58.81

Gene sequence:

>522_bases
ATCGCTACTGAGAAATCTCACCGCATCAACCGCGAGATCAGCGCACCGGAAGTCCGGCTGACCGGGGTTGAGGGAGAAGC
GCTCGGCATCGTCAAGCTGTTCGACGCGCTGCGTCTGGCAGAAGAGAAAGACGTCGACCTGGTCGAGATCGCGCCGACCG
CGCAGCCGCCCGTCTGCCGCCTGATGGACTATGGCAAGTTCAAGTATCAGGAGCAGAAAAAGGCCCATGACGCCAAGCTG
AAGCAGAAGGTGATCCAGGTGAAGGAAGTCAAGTTCCGCCCTGGCACCGACGACAACGACTACGGCGTCAAGCTGCGCAA
CGCGACGCGCTTCCTGGAGGATGGCGACAGGGTAAAGGTGACCTTGCGTTTCCGCGGCCGCGAAATGGCTCACCAGGAAC
TCGGCATGCGCGTGCTGGAGCGTATCAAGTCTGACCTGGAGGAATTCGGTCAGGTTGAGCAGATGCCTAAGATGGAAGGT
CGCCAGGCAGTGATGATGTTGGCGCCCAAGAAGAAAAAATAA

Upstream 100 bases:

>100_bases
CATGCCGTTGTCGGCGTTCGTTGAGCGACTGAAGAACGATCTCGCCAACAAGTCATGAGCTGGGCACGGCCTGTTTTTTT
GATTCTTTGAGGACATCAAC

Downstream 100 bases:

>100_bases
TGCAGCGGCGGCCGGGCGGTTCCGGCTGCGCTGAGCAGGTTCCAGACGGAAACGTCGGAAGACGCGGCAGATGTCAAAGC
CTGCCGCGATACAACAAGTG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MATEKSHRINREISAPEVRLTGVEGEALGIVKLFDALRLAEEKDVDLVEIAPTAQPPVCRLMDYGKFKYQEQKKAHDAKL
KQKVIQVKEVKFRPGTDDNDYGVKLRNATRFLEDGDRVKVTLRFRGREMAHQELGMRVLERIKSDLEEFGQVEQMPKMEG
RQAVMMLAPKKKK

Sequences:

>Translated_173_residues
MATEKSHRINREISAPEVRLTGVEGEALGIVKLFDALRLAEEKDVDLVEIAPTAQPPVCRLMDYGKFKYQEQKKAHDAKL
KQKVIQVKEVKFRPGTDDNDYGVKLRNATRFLEDGDRVKVTLRFRGREMAHQELGMRVLERIKSDLEEFGQVEQMPKMEG
RQAVMMLAPKKKK
>Mature_172_residues
ATEKSHRINREISAPEVRLTGVEGEALGIVKLFDALRLAEEKDVDLVEIAPTAQPPVCRLMDYGKFKYQEQKKAHDAKLK
QKVIQVKEVKFRPGTDDNDYGVKLRNATRFLEDGDRVKVTLRFRGREMAHQELGMRVLERIKSDLEEFGQVEQMPKMEGR
QAVMMLAPKKKK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=65.6976744186046, Blast_Score=217, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 19909; Mature: 19778

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATEKSHRINREISAPEVRLTGVEGEALGIVKLFDALRLAEEKDVDLVEIAPTAQPPVCR
CCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHH
LMDYGKFKYQEQKKAHDAKLKQKVIQVKEVKFRPGTDDNDYGVKLRNATRFLEDGDRVKV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEHHHHHHHCCCCEEEE
TLRFRGREMAHQELGMRVLERIKSDLEEFGQVEQMPKMEGRQAVMMLAPKKKK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
ATEKSHRINREISAPEVRLTGVEGEALGIVKLFDALRLAEEKDVDLVEIAPTAQPPVCR
CCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHH
LMDYGKFKYQEQKKAHDAKLKQKVIQVKEVKFRPGTDDNDYGVKLRNATRFLEDGDRVKV
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEHHHHHHHCCCCEEEE
TLRFRGREMAHQELGMRVLERIKSDLEEFGQVEQMPKMEGRQAVMMLAPKKKK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]