Click here to switch to the map view.

The map label for this gene is aat

Identifier: 187929010

GI number: 187929010

Start: 2037508

End: 2038254

Strand: Direct

Name: aat

Synonym: Rpic_1930

Alternate gene names: 187929010

Gene position: 2037508-2038254 (Clockwise)

Preceding gene: 187929009

Following gene: 187929011

Centisome position: 51.68

GC content: 66.27

Gene sequence:

>747_bases
ATGATTGCCTGGCTGGATCCGCACGATCCCTTCCCGCCGGTCGATCGCGCGCTCGGGCCGGAGTCCGAAGCGCCCGGCCT
GCTGGCCGCCAGCGCTGAGCTATCGCCGCAACGGCTGCTGATTGCGTATCGACAAGGCATTTTTCCGTGGTATGCCCAGG
GCCAGCCGGTGTTGTGGTGGAGCACCGATCCACGCATGGTGCTCCGCCCCGAAGACTTTCGCGTATCAACCACGTTTCGC
AAGACGCTGCGCCGCGTGCTTGACGACCCGGCCTGGGAAATCCGCATCGACCACGCCTTCCGCGAAACGATGGTCGCGTG
CGCCACCACAGCGCGCCCTGGACAGCACGGCACGTGGATCACCGAAGACGTCATCCAGGCGTACACAGCCCTGCACCGCC
GCGGCTACGCGCACAGCGTGGAGACGTGGCACGCCGGGCAACGTGTGGGTGGCCTGTACGGCGTGGCGCTTGGCCGCATG
TTCTACGGTGAATCGATGTTTGCGCATCGCACCGATGCCTCGAAAATCGCGCTGGCAGCGCTCTGCGCCTTCCTCGGCGG
TCAGGGCGTCGCGATGATAGACTGCCAGCAGGAAACCGAGCATCTGGCGTCGCTGGGCGGTGCCCCGGTGCCGCGCGCGG
CGTTTCTCGCACATGTGCGCGAAGCGGCCAGCGCGCCGGCCATTGTGCCGTGGCACTTCGACAAATCGGTGCTCCGCCGG
TGGACCGTACGCAATGAGCAAGCTTAA

Upstream 100 bases:

>100_bases
CTTCCGCCTCCACACGCTCGACATCTACAAGCCGATGCGCTCGGCTGCAATCGACACGCCGGCCACGACGCCGTAACACA
CAACCAACGTTGTCCGCATC

Downstream 100 bases:

>100_bases
GGAACTCCCCCTCTCGGCATTGCAGTTCTATGCCACCGCGCCTTACGCATGCAGCTACCTCGATGGCCGCCTGGCGCGCT
CGCAGGTCGCCACCCCGGCG

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIAWLDPHDPFPPVDRALGPESEAPGLLAASAELSPQRLLIAYRQGIFPWYAQGQPVLWWSTDPRMVLRPEDFRVSTTFR
KTLRRVLDDPAWEIRIDHAFRETMVACATTARPGQHGTWITEDVIQAYTALHRRGYAHSVETWHAGQRVGGLYGVALGRM
FYGESMFAHRTDASKIALAALCAFLGGQGVAMIDCQQETEHLASLGGAPVPRAAFLAHVREAASAPAIVPWHFDKSVLRR
WTVRNEQA

Sequences:

>Translated_248_residues
MIAWLDPHDPFPPVDRALGPESEAPGLLAASAELSPQRLLIAYRQGIFPWYAQGQPVLWWSTDPRMVLRPEDFRVSTTFR
KTLRRVLDDPAWEIRIDHAFRETMVACATTARPGQHGTWITEDVIQAYTALHRRGYAHSVETWHAGQRVGGLYGVALGRM
FYGESMFAHRTDASKIALAALCAFLGGQGVAMIDCQQETEHLASLGGAPVPRAAFLAHVREAASAPAIVPWHFDKSVLRR
WTVRNEQA
>Mature_248_residues
MIAWLDPHDPFPPVDRALGPESEAPGLLAASAELSPQRLLIAYRQGIFPWYAQGQPVLWWSTDPRMVLRPEDFRVSTTFR
KTLRRVLDDPAWEIRIDHAFRETMVACATTARPGQHGTWITEDVIQAYTALHRRGYAHSVETWHAGQRVGGLYGVALGRM
FYGESMFAHRTDASKIALAALCAFLGGQGVAMIDCQQETEHLASLGGAPVPRAAFLAHVREAASAPAIVPWHFDKSVLRR
WTVRNEQA

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=211, Percent_Identity=43.1279620853081, Blast_Score=181, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_RALPJ (B2UFW4)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001899497.1
- ProteinModelPortal:   B2UFW4
- SMR:   B2UFW4
- GeneID:   6286559
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_1930
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- ProtClustDB:   PRK00301
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 27650; Mature: 27650

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAWLDPHDPFPPVDRALGPESEAPGLLAASAELSPQRLLIAYRQGIFPWYAQGQPVLWW
CCEECCCCCCCCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEECCCCEEEEE
STDPRMVLRPEDFRVSTTFRKTLRRVLDDPAWEIRIDHAFRETMVACATTARPGQHGTWI
CCCCCEEECCCCCEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCH
TEDVIQAYTALHRRGYAHSVETWHAGQRVGGLYGVALGRMFYGESMFAHRTDASKIALAA
HHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHH
LCAFLGGQGVAMIDCQQETEHLASLGGAPVPRAAFLAHVREAASAPAIVPWHFDKSVLRR
HHHHHCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHH
WTVRNEQA
HHCCCCCC
>Mature Secondary Structure
MIAWLDPHDPFPPVDRALGPESEAPGLLAASAELSPQRLLIAYRQGIFPWYAQGQPVLWW
CCEECCCCCCCCCHHHHCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCCEECCCCEEEEE
STDPRMVLRPEDFRVSTTFRKTLRRVLDDPAWEIRIDHAFRETMVACATTARPGQHGTWI
CCCCCEEECCCCCEEHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCH
TEDVIQAYTALHRRGYAHSVETWHAGQRVGGLYGVALGRMFYGESMFAHRTDASKIALAA
HHHHHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHH
LCAFLGGQGVAMIDCQQETEHLASLGGAPVPRAAFLAHVREAASAPAIVPWHFDKSVLRR
HHHHHCCCCEEEEECHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHH
WTVRNEQA
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA