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The map label for this gene is mdtA [H]

Identifier: 187928973

GI number: 187928973

Start: 1994622

End: 1995830

Strand: Reverse

Name: mdtA [H]

Synonym: Rpic_1893

Alternate gene names: 187928973

Gene position: 1995830-1994622 (Counterclockwise)

Preceding gene: 187928975

Following gene: 187928972

Centisome position: 50.62

GC content: 67.16

Gene sequence:

>1209_bases
ATGCCAGCGTTGCGTTTGCCGTACCCGCATTCCGACTTCACCGGTTTCTCCGACACGCGATCTCGGCCGCGCCGGCGTTC
ATTGCCGACAGCGGCATCGGCGGCTTTGCTGGCCGGCGCGGCGCTACTGGCCGGCTGCAGCAAGGAGGCACCCAAGGCGC
CCGTGGTGCGCCCGGTGCGGACCATGACAGTGACCAGCGAGCAGGGCGCCGGCACAGCGGAATTCTCCGGCGACGTACGC
CCGCGCATTGAATCTCGCCTGGGCTTCCGCGTGCCCGGCAAGATCGTTGCCCGGCTGGTGGACGTCGGTGCCACGGTCAA
GAAAGGCCAGGTGCTGGCGAGGTTGGACCCCACGGATCTGGCCCTCGCCCAGCAATCGGCCCAGGCGCAGTTATCGGCGG
CCAAGACTGATCGCGATCTGGCCGCGGCTGACCTCAAGCGCTATTCCGAACTGTTCGCCAAGGGTTTCATCAGCGCGGCT
GAGCAGCAACGCCATCAAGCCAACTATGACGCCGCGCAAGCCCGCTACGAGCAGGCCGGAGCTGGCTATCGCAACCAGGT
GAATCAAGCCGGCTATGCCACGCTCGAAGCCGACGCCGATGGCGTGGTGACGGGCGTCGACGCCGAAGTCGGACAGGTGG
TGTCCGCAGGCCAACCGGTGGTGCGCGTGGCGCAAACGGCAGAGAAGGAAGTCGTGGTCGGCATTCCCGAGGATCAGGTG
GACACGCTGCGCAAATCGCCCGAGGTGAGCGTGAAGCTGTGGGCCGATCAGTCGCGCAGCATTCCGGCCAAGGTGCGCGA
GATTGCGCCGGCAGCCGACCCGGTCACACGCACGTACACCGTCAAGATTTCGGTACCGAATCCACCGCCGGAACTCAAGC
TTGGCATGACCGCAGCGGCCACCTTTGTGCGGCCCGGCGGCGGTGGCGATAGCGGCGGCATGGGCGTGCGGGTGCCGATG
AGCGCGCTGCTCCAGGATCAAGGCAAAAACGTGGTCTGGCTGTACGACGCCGCATCGCAAACGGTGAAGCCCGTGCCGGT
GACGGTGGGCGCGCCGCGCGACAACGTGCTACTGGTGACGAGCGGCCTGCAGCCCGGCCAGACGATCGTGACCGCTGGCG
TGCACTTGCTCAAGGCAGGCCAGAAGGTGATGCCGATGGCGCCAGCCGATCAGCCGTCGGCGCAGTCCGCCATCACGCCG
CGCCGGTAA

Upstream 100 bases:

>100_bases
CATCTGCCAAGAAAAGTCAATCAGACGCGGCCGTGTCGTTGACCCTGCGCATTGCCGTGGGTATATTACTGACCGGTCAG
TTATTTACTGAGAGCGTGTC

Downstream 100 bases:

>100_bases
GCCGCATCCGGCTCCCGCCCCAACACGCCAACCTTCGCGCGTATGGAACATTCCCGTTTCAACCTGTCACGCTGGGCGCT
TGAACATCAACCGCTCACGC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MPALRLPYPHSDFTGFSDTRSRPRRRSLPTAASAALLAGAALLAGCSKEAPKAPVVRPVRTMTVTSEQGAGTAEFSGDVR
PRIESRLGFRVPGKIVARLVDVGATVKKGQVLARLDPTDLALAQQSAQAQLSAAKTDRDLAAADLKRYSELFAKGFISAA
EQQRHQANYDAAQARYEQAGAGYRNQVNQAGYATLEADADGVVTGVDAEVGQVVSAGQPVVRVAQTAEKEVVVGIPEDQV
DTLRKSPEVSVKLWADQSRSIPAKVREIAPAADPVTRTYTVKISVPNPPPELKLGMTAAATFVRPGGGGDSGGMGVRVPM
SALLQDQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVTSGLQPGQTIVTAGVHLLKAGQKVMPMAPADQPSAQSAITP
RR

Sequences:

>Translated_402_residues
MPALRLPYPHSDFTGFSDTRSRPRRRSLPTAASAALLAGAALLAGCSKEAPKAPVVRPVRTMTVTSEQGAGTAEFSGDVR
PRIESRLGFRVPGKIVARLVDVGATVKKGQVLARLDPTDLALAQQSAQAQLSAAKTDRDLAAADLKRYSELFAKGFISAA
EQQRHQANYDAAQARYEQAGAGYRNQVNQAGYATLEADADGVVTGVDAEVGQVVSAGQPVVRVAQTAEKEVVVGIPEDQV
DTLRKSPEVSVKLWADQSRSIPAKVREIAPAADPVTRTYTVKISVPNPPPELKLGMTAAATFVRPGGGGDSGGMGVRVPM
SALLQDQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVTSGLQPGQTIVTAGVHLLKAGQKVMPMAPADQPSAQSAITP
RR
>Mature_401_residues
PALRLPYPHSDFTGFSDTRSRPRRRSLPTAASAALLAGAALLAGCSKEAPKAPVVRPVRTMTVTSEQGAGTAEFSGDVRP
RIESRLGFRVPGKIVARLVDVGATVKKGQVLARLDPTDLALAQQSAQAQLSAAKTDRDLAAADLKRYSELFAKGFISAAE
QQRHQANYDAAQARYEQAGAGYRNQVNQAGYATLEADADGVVTGVDAEVGQVVSAGQPVVRVAQTAEKEVVVGIPEDQVD
TLRKSPEVSVKLWADQSRSIPAKVREIAPAADPVTRTYTVKISVPNPPPELKLGMTAAATFVRPGGGGDSGGMGVRVPMS
ALLQDQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVTSGLQPGQTIVTAGVHLLKAGQKVMPMAPADQPSAQSAITPR
R

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=322, Percent_Identity=26.3975155279503, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42217; Mature: 42086

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALRLPYPHSDFTGFSDTRSRPRRRSLPTAASAALLAGAALLAGCSKEAPKAPVVRPVR
CCCCCCCCCCCCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
TMTVTSEQGAGTAEFSGDVRPRIESRLGFRVPGKIVARLVDVGATVKKGQVLARLDPTDL
EEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCHHH
ALAQQSAQAQLSAAKTDRDLAAADLKRYSELFAKGFISAAEQQRHQANYDAAQARYEQAG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGYRNQVNQAGYATLEADADGVVTGVDAEVGQVVSAGQPVVRVAQTAEKEVVVGIPEDQV
CCHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHH
DTLRKSPEVSVKLWADQSRSIPAKVREIAPAADPVTRTYTVKISVPNPPPELKLGMTAAA
HHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEECCEEHE
TFVRPGGGGDSGGMGVRVPMSALLQDQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVT
EEECCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEEE
SGLQPGQTIVTAGVHLLKAGQKVMPMAPADQPSAQSAITPRR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PALRLPYPHSDFTGFSDTRSRPRRRSLPTAASAALLAGAALLAGCSKEAPKAPVVRPVR
CCCCCCCCCCCCCCCCHHHCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
TMTVTSEQGAGTAEFSGDVRPRIESRLGFRVPGKIVARLVDVGATVKKGQVLARLDPTDL
EEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCHHH
ALAQQSAQAQLSAAKTDRDLAAADLKRYSELFAKGFISAAEQQRHQANYDAAQARYEQAG
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGYRNQVNQAGYATLEADADGVVTGVDAEVGQVVSAGQPVVRVAQTAEKEVVVGIPEDQV
CCHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHH
DTLRKSPEVSVKLWADQSRSIPAKVREIAPAADPVTRTYTVKISVPNPPPELKLGMTAAA
HHHHCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCEEEEEEEEECCCCCCCEEECCEEHE
TFVRPGGGGDSGGMGVRVPMSALLQDQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVT
EEECCCCCCCCCCCEEEHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEECCCCCCEEEEE
SGLQPGQTIVTAGVHLLKAGQKVMPMAPADQPSAQSAITPRR
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]