| Definition | Ralstonia pickettii 12J chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010682 |
| Length | 3,942,557 |
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The map label for this gene is lon [H]
Identifier: 187928948
GI number: 187928948
Start: 1965578
End: 1967992
Strand: Reverse
Name: lon [H]
Synonym: Rpic_1867
Alternate gene names: 187928948
Gene position: 1967992-1965578 (Counterclockwise)
Preceding gene: 187928949
Following gene: 187928947
Centisome position: 49.92
GC content: 61.04
Gene sequence:
>2415_bases ATGTCCGGAACCCAACTTTTACCCGCTGAGCAGATTCGCCTGCCGCTGTTGCCGCTGCGTGACGTCGTGGTGTTTCCGCA CATGGTGATTCCGCTGTTCGTGGGGCGCCCCAAATCCATCAAGGCGCTGGAAGCTGCGATGGAGGCGGGCAAGAGCATCA TGCTCGTGGCGCAAAAGACTGCCGCCAAGGACGAGCCGACCGATAAGGATCTGTATGAGGTCGGCTGTATCGCCAACATT CTGCAGATGCTGAAGCTGCCGGACGGCACCGTGAAGGTGCTGGTCGAGGGCACGCAGCGCGCCAATATCCTGTCCGTCAC CGACGACGAATCGCACTTCTTCTGCGAAGCTGTGCCCGTCGGCCCGGAACCCACTGAATCGGCTGAGACCGAGGCGCTGC GTCGCGCCATCGTGTCGCAGTTCGATCAGTACGTGAAGCTGAACAAGAAGATCCCGCCTGAAATCCTGACTTCGTTGTCG GGCATCGACGAGCCGGGTCGTCTGGCCGACACCATTGCTGCGCATCTGCCGATTAAGCTCGAGCAGAAGCAGAAGATTCT CGAGATGTTCAATGTGACCGAACGTCTGGAGAGCCTGCTTTCGCAGCTGGAAGGCGAGATCGACATCCTGCAGGTGGAAA AGCGCATCCGTGGCCGCGTCAAGCGCCAGATGGAGAAGAGCCAGCGCGAGTACTACCTGAACGAGCAGGTCAAGGCCATC CAGAAGGAACTGGGCGAAGGCGAGGAAGGCGCCGATCTCGAAGAGCTGGACAAGAAGATCAAGGCCGCCCGCATGCCGAA GGAGGCCAAGAAGAAGGCCGAGTCCGAGTTCAAGAAGCTCAAGCTGATGTCGCCGATGTCGGCCGAGGCGACGGTCGTGC GCAACTACATCGACACGTTGGTTGGTCTGCCGTGGCGCAAGAAGAGCAAGGTGAACAACGATCTGTCGAACGCCGAGCAG GTGCTGGATCAGGACCACTATGGTTTGGAGAAGGTCAAGGAACGCATCCTTGAATACCTCGCGGTGCAACAGCGCGTCGA CAAACTGAAGGCGCCGATCCTGTGCCTCGTGGGGCCGCCGGGGGTTGGCAAGACGTCGCTCGGGCAGTCGGTGGCGCGTG CAACGAACCGCAAGTTCGTGCGCATGGCGCTGGGTGGCGTGCGTGACGAGGCCGAGATTCGCGGTCACCGCCGTACGTAC ATCGGGTCGATGCCGGGCAAGATCCTGCAGAGCCTGACGAAGGTCGGCGTGCGCAATCCGTTGTTCCTGCTGGACGAGAT CGACAAGATGGGTGCGGATTTCCGCGGCGATCCGTCGTCGGCCCTGCTCGAAGTGCTGGACCCGGAACAGAACCACACGT TCCAGGACCACTACATCGAAGTGGACTTCGACCTGTCGGATGTGATGTTCGTGGCGACGTCGAACTCGCTGAACATTCCG GCGCCGCTGCTGGACCGGATGGAAGTGATTCGTCTGTCGGGCTACACGGAAGACGAAAAGGTCAACATCGCCCGTCGCTA CTTGCTGCCCAAGCAGATCAAGAACAATGGTCTGAAAGAGGGCGAGATCGAGGTGACCGAAGCCGCGCTGCGCGACATCA TCCGCTACTACACGCGGGAAGCTGGTGTGCGTTCCCTGGAACGCGAGGTCTCGAAGATCTGCCGCAAGGTCGTCAAGCAA CTGCTGCTGAAGAAGGAAGCCAATACGTCCGTGAAGGTGGATTCGGACAACCTGGACAAATTCCTTGGCGTGCGTCGTTT CGACTTCGGTCTGGCCGGCAAGGAAGACCAGGTGGGCCAGGTGACTGGTTTGGCATGGACCGAAGTGGGCGGCGATCTGC TGACCATCGAGGCAGCGCTGATGCCGGGCAAGGGCAACATCACCCGCACCGGTTCGTTGGGCGACGTGATGAAGGAGTCG GTTGAGGCTGCGCGGTCGGTGGTGCGTTCGCGTTCGGCACGGCTGGGTATCAAGGATGAGATGTTCGAGAAGCGCGACAT TCACATCCACGTGCCCGAAGGTGCGACGCCCAAGGATGGCCCTTCGGCGGGTATTGCGATGACGACGGCGCTGGTGTCGG TGCTGACCGGGATCCCGGTGCGCGCTGATGTGGCGATGACCGGCGAAATCACCCTGCGCGGCGAAGTGCTGCCGATCGGC GGCTTGAAGGAAAAGCTGCTGGCTGCACACCGCGGCGGCATCAAGCTGGCGCTGATTCCGGAGGAGAACGTCAAGGACTT GGCGGACATTCCGGACAACGTGAAGAACAGCATCGAGATTCAGCCGGTGCGCTGGATCGACAAGGTGCTGGAACTCGCGC TGGTGCGCAAGCCGGAGCCTCTTCCGGAGGAAGAAGCCAAGCCGGCGCCCGCCCAGGGCGATGACGGCAAGTCGCAGGAA ATGGTGCATCACTGA
Upstream 100 bases:
>100_bases TTGCTTCGGGAAACCGGGTCGGCATGCGACTTGCAGCAGCGGTCTTGTAAAACCGCCGCTGTGCCCAATTTAGCCCTTAC ATGACTTTCTGGGGAAAATA
Downstream 100 bases:
>100_bases CACCGTAGCCTGCCGAGGTTGAAGAAGGGCCCGACATGTTCGGGCCCTTTTTCTTTGCGCTGGCTGCGACATGTGGCACA CAGTTCTTCGCCTTGACACG
Product: ATP-dependent protease La
Products: NA
Alternate protein names: ATP-dependent protease La [H]
Number of amino acids: Translated: 804; Mature: 803
Protein sequence:
>804_residues MSGTQLLPAEQIRLPLLPLRDVVVFPHMVIPLFVGRPKSIKALEAAMEAGKSIMLVAQKTAAKDEPTDKDLYEVGCIANI LQMLKLPDGTVKVLVEGTQRANILSVTDDESHFFCEAVPVGPEPTESAETEALRRAIVSQFDQYVKLNKKIPPEILTSLS GIDEPGRLADTIAAHLPIKLEQKQKILEMFNVTERLESLLSQLEGEIDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAI QKELGEGEEGADLEELDKKIKAARMPKEAKKKAESEFKKLKLMSPMSAEATVVRNYIDTLVGLPWRKKSKVNNDLSNAEQ VLDQDHYGLEKVKERILEYLAVQQRVDKLKAPILCLVGPPGVGKTSLGQSVARATNRKFVRMALGGVRDEAEIRGHRRTY IGSMPGKILQSLTKVGVRNPLFLLDEIDKMGADFRGDPSSALLEVLDPEQNHTFQDHYIEVDFDLSDVMFVATSNSLNIP APLLDRMEVIRLSGYTEDEKVNIARRYLLPKQIKNNGLKEGEIEVTEAALRDIIRYYTREAGVRSLEREVSKICRKVVKQ LLLKKEANTSVKVDSDNLDKFLGVRRFDFGLAGKEDQVGQVTGLAWTEVGGDLLTIEAALMPGKGNITRTGSLGDVMKES VEAARSVVRSRSARLGIKDEMFEKRDIHIHVPEGATPKDGPSAGIAMTTALVSVLTGIPVRADVAMTGEITLRGEVLPIG GLKEKLLAAHRGGIKLALIPEENVKDLADIPDNVKNSIEIQPVRWIDKVLELALVRKPEPLPEEEAKPAPAQGDDGKSQE MVHH
Sequences:
>Translated_804_residues MSGTQLLPAEQIRLPLLPLRDVVVFPHMVIPLFVGRPKSIKALEAAMEAGKSIMLVAQKTAAKDEPTDKDLYEVGCIANI LQMLKLPDGTVKVLVEGTQRANILSVTDDESHFFCEAVPVGPEPTESAETEALRRAIVSQFDQYVKLNKKIPPEILTSLS GIDEPGRLADTIAAHLPIKLEQKQKILEMFNVTERLESLLSQLEGEIDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAI QKELGEGEEGADLEELDKKIKAARMPKEAKKKAESEFKKLKLMSPMSAEATVVRNYIDTLVGLPWRKKSKVNNDLSNAEQ VLDQDHYGLEKVKERILEYLAVQQRVDKLKAPILCLVGPPGVGKTSLGQSVARATNRKFVRMALGGVRDEAEIRGHRRTY IGSMPGKILQSLTKVGVRNPLFLLDEIDKMGADFRGDPSSALLEVLDPEQNHTFQDHYIEVDFDLSDVMFVATSNSLNIP APLLDRMEVIRLSGYTEDEKVNIARRYLLPKQIKNNGLKEGEIEVTEAALRDIIRYYTREAGVRSLEREVSKICRKVVKQ LLLKKEANTSVKVDSDNLDKFLGVRRFDFGLAGKEDQVGQVTGLAWTEVGGDLLTIEAALMPGKGNITRTGSLGDVMKES VEAARSVVRSRSARLGIKDEMFEKRDIHIHVPEGATPKDGPSAGIAMTTALVSVLTGIPVRADVAMTGEITLRGEVLPIG GLKEKLLAAHRGGIKLALIPEENVKDLADIPDNVKNSIEIQPVRWIDKVLELALVRKPEPLPEEEAKPAPAQGDDGKSQE MVHH >Mature_803_residues SGTQLLPAEQIRLPLLPLRDVVVFPHMVIPLFVGRPKSIKALEAAMEAGKSIMLVAQKTAAKDEPTDKDLYEVGCIANIL QMLKLPDGTVKVLVEGTQRANILSVTDDESHFFCEAVPVGPEPTESAETEALRRAIVSQFDQYVKLNKKIPPEILTSLSG IDEPGRLADTIAAHLPIKLEQKQKILEMFNVTERLESLLSQLEGEIDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAIQ KELGEGEEGADLEELDKKIKAARMPKEAKKKAESEFKKLKLMSPMSAEATVVRNYIDTLVGLPWRKKSKVNNDLSNAEQV LDQDHYGLEKVKERILEYLAVQQRVDKLKAPILCLVGPPGVGKTSLGQSVARATNRKFVRMALGGVRDEAEIRGHRRTYI GSMPGKILQSLTKVGVRNPLFLLDEIDKMGADFRGDPSSALLEVLDPEQNHTFQDHYIEVDFDLSDVMFVATSNSLNIPA PLLDRMEVIRLSGYTEDEKVNIARRYLLPKQIKNNGLKEGEIEVTEAALRDIIRYYTREAGVRSLEREVSKICRKVVKQL LLKKEANTSVKVDSDNLDKFLGVRRFDFGLAGKEDQVGQVTGLAWTEVGGDLLTIEAALMPGKGNITRTGSLGDVMKESV EAARSVVRSRSARLGIKDEMFEKRDIHIHVPEGATPKDGPSAGIAMTTALVSVLTGIPVRADVAMTGEITLRGEVLPIGG LKEKLLAAHRGGIKLALIPEENVKDLADIPDNVKNSIEIQPVRWIDKVLELALVRKPEPLPEEEAKPAPAQGDDGKSQEM VHH
Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced
COG id: COG0466
COG function: function code O; ATP-dependent Lon protease, bacterial type
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Lon domain [H]
Homologues:
Organism=Homo sapiens, GI31377667, Length=828, Percent_Identity=38.4057971014493, Blast_Score=529, Evalue=1e-150, Organism=Homo sapiens, GI21396489, Length=677, Percent_Identity=41.2112259970458, Blast_Score=508, Evalue=1e-143, Organism=Escherichia coli, GI1786643, Length=771, Percent_Identity=70.6874189364462, Blast_Score=1100, Evalue=0.0, Organism=Caenorhabditis elegans, GI17505831, Length=708, Percent_Identity=40.5367231638418, Blast_Score=495, Evalue=1e-140, Organism=Caenorhabditis elegans, GI17556486, Length=542, Percent_Identity=39.4833948339483, Blast_Score=421, Evalue=1e-117, Organism=Saccharomyces cerevisiae, GI6319449, Length=709, Percent_Identity=41.0437235543018, Blast_Score=514, Evalue=1e-146, Organism=Drosophila melanogaster, GI24666867, Length=631, Percent_Identity=44.3740095087163, Blast_Score=518, Evalue=1e-147, Organism=Drosophila melanogaster, GI221513036, Length=631, Percent_Identity=44.3740095087163, Blast_Score=518, Evalue=1e-147,
Paralogues:
None
Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR003959 - InterPro: IPR008269 - InterPro: IPR004815 - InterPro: IPR003111 - InterPro: IPR001984 - InterPro: IPR015947 - InterPro: IPR020568 [H]
Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]
EC number: =3.4.21.53 [H]
Molecular weight: Translated: 89173; Mature: 89042
Theoretical pI: Translated: 6.55; Mature: 6.55
Prosite motif: PS01046 LON_SER
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSGTQLLPAEQIRLPLLPLRDVVVFPHMVIPLFVGRPKSIKALEAAMEAGKSIMLVAQKT CCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEHH AAKDEPTDKDLYEVGCIANILQMLKLPDGTVKVLVEGTQRANILSVTDDESHFFCEAVPV CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEECC GPEPTESAETEALRRAIVSQFDQYVKLNKKIPPEILTSLSGIDEPGRLADTIAAHLPIKL CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCH EQKQKILEMFNVTERLESLLSQLEGEIDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAI HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QKELGEGEEGADLEELDKKIKAARMPKEAKKKAESEFKKLKLMSPMSAEATVVRNYIDTL HHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH VGLPWRKKSKVNNDLSNAEQVLDQDHYGLEKVKERILEYLAVQQRVDKLKAPILCLVGPP HCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC GVGKTSLGQSVARATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQSLTKVGVRNP CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCC LFLLDEIDKMGADFRGDPSSALLEVLDPEQNHTFQDHYIEVDFDLSDVMFVATSNSLNIP HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCC APLLDRMEVIRLSGYTEDEKVNIARRYLLPKQIKNNGLKEGEIEVTEAALRDIIRYYTRE HHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH AGVRSLEREVSKICRKVVKQLLLKKEANTSVKVDSDNLDKFLGVRRFDFGLAGKEDQVGQ HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCHHHCCCCCCCCCCCCC VTGLAWTEVGGDLLTIEAALMPGKGNITRTGSLGDVMKESVEAARSVVRSRSARLGIKDE EECEEHHHCCCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH MFEKRDIHIHVPEGATPKDGPSAGIAMTTALVSVLTGIPVRADVAMTGEITLRGEVLPIG HHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECEEEECEEEEECEEEECC GLKEKLLAAHRGGIKLALIPEENVKDLADIPDNVKNSIEIQPVRWIDKVLELALVRKPEP CHHHHHHHHHCCCEEEEEECCCCHHHHHCCCHHHHCCEEECHHHHHHHHHHHHHHCCCCC LPEEEAKPAPAQGDDGKSQEMVHH CCCCCCCCCCCCCCCCCCHHHCCC >Mature Secondary Structure SGTQLLPAEQIRLPLLPLRDVVVFPHMVIPLFVGRPKSIKALEAAMEAGKSIMLVAQKT CCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEEEHH AAKDEPTDKDLYEVGCIANILQMLKLPDGTVKVLVEGTQRANILSVTDDESHFFCEAVPV CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCCEEEEEECC GPEPTESAETEALRRAIVSQFDQYVKLNKKIPPEILTSLSGIDEPGRLADTIAAHLPIKL CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCH EQKQKILEMFNVTERLESLLSQLEGEIDILQVEKRIRGRVKRQMEKSQREYYLNEQVKAI HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH QKELGEGEEGADLEELDKKIKAARMPKEAKKKAESEFKKLKLMSPMSAEATVVRNYIDTL HHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH VGLPWRKKSKVNNDLSNAEQVLDQDHYGLEKVKERILEYLAVQQRVDKLKAPILCLVGPP HCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC GVGKTSLGQSVARATNRKFVRMALGGVRDEAEIRGHRRTYIGSMPGKILQSLTKVGVRNP CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHCCCCHHHHHHHHHHHCCCCC LFLLDEIDKMGADFRGDPSSALLEVLDPEQNHTFQDHYIEVDFDLSDVMFVATSNSLNIP HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEEECCCCCCC APLLDRMEVIRLSGYTEDEKVNIARRYLLPKQIKNNGLKEGEIEVTEAALRDIIRYYTRE HHHHHHHHHHHHCCCCCCHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH AGVRSLEREVSKICRKVVKQLLLKKEANTSVKVDSDNLDKFLGVRRFDFGLAGKEDQVGQ HHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCHHHCCCCCCCCCCCCC VTGLAWTEVGGDLLTIEAALMPGKGNITRTGSLGDVMKESVEAARSVVRSRSARLGIKDE EECEEHHHCCCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH MFEKRDIHIHVPEGATPKDGPSAGIAMTTALVSVLTGIPVRADVAMTGEITLRGEVLPIG HHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECEEEECEEEEECEEEECC GLKEKLLAAHRGGIKLALIPEENVKDLADIPDNVKNSIEIQPVRWIDKVLELALVRKPEP CHHHHHHHHHCCCEEEEEECCCCHHHHHCCCHHHHCCEEECHHHHHHHHHHHHHHCCCCC LPEEEAKPAPAQGDDGKSQEMVHH CCCCCCCCCCCCCCCCCCHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8981986; 12620739 [H]