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The map label for this gene is cusB [H]

Identifier: 187928890

GI number: 187928890

Start: 1898783

End: 1900315

Strand: Direct

Name: cusB [H]

Synonym: Rpic_1808

Alternate gene names: 187928890

Gene position: 1898783-1900315 (Clockwise)

Preceding gene: 187928889

Following gene: 187928891

Centisome position: 48.16

GC content: 65.95

Gene sequence:

>1533_bases
ATGAAAAAACAGATTATCGCCACGGCGGCCGGCCTCGCCATTCTCGGCGCCGCGATGTATGGCGCTTACCACTTCGGCGT
CACGCAGGGAGCACGGTCGGCACAATCGTCGGCGCCGGCCAGCGCGGCATCCGGTCTCAAGGCCGGCGACGTCGATCCCA
AGACCGGCAAAAAGGTACTGTACTGGCACGACCCCATGGTGCCCGGACAGCGTTTCGACAAGCCGGGCAAATCCCCCTTC
ATGGACATGCAGTTGGTGCCGGTCTATGCGGACGGGGATAGCGGTGCCAGCGGCATCACGGTCGATAGCCGTGTCGCGCA
AAACCTCGGCATCCGCACGGCCGAAGTCAAAGCCGGCCGGTTGAGCACGGTACTGGAGGCGCCCGGCAACATCGTCATCG
ACGAGCGCAGCGTGCAAGTAATCCAGGCGCGCACGAACGCCTTCGTCCAGCACGTCGCGGTCAGGGCGACGCTTGACCCA
GTTCGGCGTGGGCAGGCACTGGTGACTCTGTATTCGCCGGACTGGGTGGCGGCCCAGGAAGAGTATCTGGCCGTGTTGCG
CCAGTCGGCACACGGTCAGGCCGATCTCGCCAGTGCGGCCAAGGCGCGCATGCTGCAGACCGGCATGACGCCCGGGCAGG
TCAGCGCCGTCGAGGCATCCGGACGGCTGCAGCCCAGCGTGGGCATCGCGAGCCCCATCGATGGCATCGTGACCGAGGTC
GCGGTGCGAGACGGGATGACAGTCTCGCCCGGCATGACTCTGTTCCGTCTGGCCGACTTAAGCCAGGTCTGGGTGGTTGC
CGAGGTGCCGGAAGGCCAGGCCCGCACCATTGCGCCCGGCCTGGCGGTCAAGGTGACACCGACCGGGGCGGCCGAGCCGC
TGGTCGGCAAGGTCGACACCGTGTTGCCCGACGTCAACCCGGCGACGCGGACCATCAAGGTGCGCATCGTCCTGCCCAAC
AAGGGCCGGCACCTGTTGCCGGGCATGTTTGCCACGGTTCGCTTCGACAGCGGCGAGCAGCAGGACGTACTGACCATCCC
GTTGGAAGCCGTCATCCGTACCGGTCAGCGCAGCATTGTCATGGTCGATGGAGGCCAGGCCGGCTTTGTGGCCACCGAGA
TCAAGACCGGGCGCGAGGCCGGTGGAATGGTCGAGGTCCTGACTGGTCTCAAGGCTGGCCAGAAGGTCGTTACGTCCGGC
CAGTTCCTGATCGATTCGGAAGCCAGCCTGCGTGGAACCACCGAGCGTATGGCGGTACCGGCCGCGGCATCTGCGCCGGC
AGCGGCCAACGCCGAACACGAAGGCGTCGGTCGCATCGAGACCGTCACGGGTGAAGGCCTGACGATCTCGCATGGTCCGA
TTCCCTCGATCCAGTGGGGGGCCATGACAATGGAGTTTGCGGCACCTCCCACAGGGTTGCCCAAGGGTTTTAAGCCCGGC
GATCGCGTCCGCTTCCGCTTCCATCTGAACGCCGAGGGCATGGCGATTCTGTCTTCGGTCGAGCCCGCCGCTGGCACGGG
GAGCAAACCATGA

Upstream 100 bases:

>100_bases
GACTCGCGCTGGAGGCCAAGACGGCCAAGCTGTGGGCGGACCTGACCTTCCTGGTCCCGCTGCCCACCGCGCAGACCGAG
TCCGCCATCAAGGAACCCAA

Downstream 100 bases:

>100_bases
TCGCCCGGCTGATTCTCGCGTCCATCCGCAACCGCTTCCTGATCCTGCTGGCGACGCTGATGTTGACCGCGTGGGGATTG
TGGGCCGTCCGCAGCACCCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 510; Mature: 510

Protein sequence:

>510_residues
MKKQIIATAAGLAILGAAMYGAYHFGVTQGARSAQSSAPASAASGLKAGDVDPKTGKKVLYWHDPMVPGQRFDKPGKSPF
MDMQLVPVYADGDSGASGITVDSRVAQNLGIRTAEVKAGRLSTVLEAPGNIVIDERSVQVIQARTNAFVQHVAVRATLDP
VRRGQALVTLYSPDWVAAQEEYLAVLRQSAHGQADLASAAKARMLQTGMTPGQVSAVEASGRLQPSVGIASPIDGIVTEV
AVRDGMTVSPGMTLFRLADLSQVWVVAEVPEGQARTIAPGLAVKVTPTGAAEPLVGKVDTVLPDVNPATRTIKVRIVLPN
KGRHLLPGMFATVRFDSGEQQDVLTIPLEAVIRTGQRSIVMVDGGQAGFVATEIKTGREAGGMVEVLTGLKAGQKVVTSG
QFLIDSEASLRGTTERMAVPAAASAPAAANAEHEGVGRIETVTGEGLTISHGPIPSIQWGAMTMEFAAPPTGLPKGFKPG
DRVRFRFHLNAEGMAILSSVEPAAGTGSKP

Sequences:

>Translated_510_residues
MKKQIIATAAGLAILGAAMYGAYHFGVTQGARSAQSSAPASAASGLKAGDVDPKTGKKVLYWHDPMVPGQRFDKPGKSPF
MDMQLVPVYADGDSGASGITVDSRVAQNLGIRTAEVKAGRLSTVLEAPGNIVIDERSVQVIQARTNAFVQHVAVRATLDP
VRRGQALVTLYSPDWVAAQEEYLAVLRQSAHGQADLASAAKARMLQTGMTPGQVSAVEASGRLQPSVGIASPIDGIVTEV
AVRDGMTVSPGMTLFRLADLSQVWVVAEVPEGQARTIAPGLAVKVTPTGAAEPLVGKVDTVLPDVNPATRTIKVRIVLPN
KGRHLLPGMFATVRFDSGEQQDVLTIPLEAVIRTGQRSIVMVDGGQAGFVATEIKTGREAGGMVEVLTGLKAGQKVVTSG
QFLIDSEASLRGTTERMAVPAAASAPAAANAEHEGVGRIETVTGEGLTISHGPIPSIQWGAMTMEFAAPPTGLPKGFKPG
DRVRFRFHLNAEGMAILSSVEPAAGTGSKP
>Mature_510_residues
MKKQIIATAAGLAILGAAMYGAYHFGVTQGARSAQSSAPASAASGLKAGDVDPKTGKKVLYWHDPMVPGQRFDKPGKSPF
MDMQLVPVYADGDSGASGITVDSRVAQNLGIRTAEVKAGRLSTVLEAPGNIVIDERSVQVIQARTNAFVQHVAVRATLDP
VRRGQALVTLYSPDWVAAQEEYLAVLRQSAHGQADLASAAKARMLQTGMTPGQVSAVEASGRLQPSVGIASPIDGIVTEV
AVRDGMTVSPGMTLFRLADLSQVWVVAEVPEGQARTIAPGLAVKVTPTGAAEPLVGKVDTVLPDVNPATRTIKVRIVLPN
KGRHLLPGMFATVRFDSGEQQDVLTIPLEAVIRTGQRSIVMVDGGQAGFVATEIKTGREAGGMVEVLTGLKAGQKVVTSG
QFLIDSEASLRGTTERMAVPAAASAPAAANAEHEGVGRIETVTGEGLTISHGPIPSIQWGAMTMEFAAPPTGLPKGFKPG
DRVRFRFHLNAEGMAILSSVEPAAGTGSKP

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=370, Percent_Identity=36.7567567567568, Blast_Score=238, Evalue=7e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 53093; Mature: 53093

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQIIATAAGLAILGAAMYGAYHFGVTQGARSAQSSAPASAASGLKAGDVDPKTGKKVL
CCCEEEHHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCHHHCCCCCCCCCCCCCCEEE
YWHDPMVPGQRFDKPGKSPFMDMQLVPVYADGDSGASGITVDSRVAQNLGIRTAEVKAGR
EEECCCCCCHHCCCCCCCCCCCEEEEEEEECCCCCCCCCEEHHHHHHHCCCEEEEECCCC
LSTVLEAPGNIVIDERSVQVIQARTNAFVQHVAVRATLDPVRRGQALVTLYSPDWVAAQE
HHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
EYLAVLRQSAHGQADLASAAKARMLQTGMTPGQVSAVEASGRLQPSVGIASPIDGIVTEV
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
AVRDGMTVSPGMTLFRLADLSQVWVVAEVPEGQARTIAPGLAVKVTPTGAAEPLVGKVDT
HHHCCCEECCCCCEEEECCCCEEEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCHHH
VLPDVNPATRTIKVRIVLPNKGRHLLPGMFATVRFDSGEQQDVLTIPLEAVIRTGQRSIV
HCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEECHHHHHHCCCCEEE
MVDGGQAGFVATEIKTGREAGGMVEVLTGLKAGQKVVTSGQFLIDSEASLRGTTERMAVP
EEECCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEECCCEEEECCCCCCCCHHHEECC
AAASAPAAANAEHEGVGRIETVTGEGLTISHGPIPSIQWGAMTMEFAAPPTGLPKGFKPG
CCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEECCEEEEECCCCCCCCCCCCCC
DRVRFRFHLNAEGMAILSSVEPAAGTGSKP
CEEEEEEEECCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MKKQIIATAAGLAILGAAMYGAYHFGVTQGARSAQSSAPASAASGLKAGDVDPKTGKKVL
CCCEEEHHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCHHHCCCCCCCCCCCCCCEEE
YWHDPMVPGQRFDKPGKSPFMDMQLVPVYADGDSGASGITVDSRVAQNLGIRTAEVKAGR
EEECCCCCCHHCCCCCCCCCCCEEEEEEEECCCCCCCCCEEHHHHHHHCCCEEEEECCCC
LSTVLEAPGNIVIDERSVQVIQARTNAFVQHVAVRATLDPVRRGQALVTLYSPDWVAAQE
HHHHHHCCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHH
EYLAVLRQSAHGQADLASAAKARMLQTGMTPGQVSAVEASGRLQPSVGIASPIDGIVTEV
HHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHH
AVRDGMTVSPGMTLFRLADLSQVWVVAEVPEGQARTIAPGLAVKVTPTGAAEPLVGKVDT
HHHCCCEECCCCCEEEECCCCEEEEEEECCCCCCEEECCCEEEEEECCCCCCCCCCCHHH
VLPDVNPATRTIKVRIVLPNKGRHLLPGMFATVRFDSGEQQDVLTIPLEAVIRTGQRSIV
HCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCEEEECHHHHHHCCCCEEE
MVDGGQAGFVATEIKTGREAGGMVEVLTGLKAGQKVVTSGQFLIDSEASLRGTTERMAVP
EEECCCCCEEEEEECCCCCCCCHHHHHHHCCCCCEEEECCCEEEECCCCCCCCHHHEECC
AAASAPAAANAEHEGVGRIETVTGEGLTISHGPIPSIQWGAMTMEFAAPPTGLPKGFKPG
CCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEECCEEEEECCCCCCCCCCCCCC
DRVRFRFHLNAEGMAILSSVEPAAGTGSKP
CEEEEEEEECCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]